GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

(2012) Steffan D Bos et al.   ANNALS OF THE RHEUMATIC DISEASES

Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice

(2012) Hwanhee Oh et al.   ARTHRITIS AND RHEUMATISM

A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes

(2012) Bin Ma et al.   ARTHRITIS AND RHEUMATISM

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

(2012) J. C. H. Leijten et al.   ARTHRITIS AND RHEUMATISM

The effect of platelet lysate supplementation of a dextran-based hydrogel on cartilage formation

(2012) Liliana S. Moreira Teixeira et al.   BIOMATERIALS

Hypoxia Inhibits Hypertrophic Differentiation and Endochondral Ossification in Explanted Tibiae

(2012) Jeroen C. H. Leijten et al.   PLoS One

Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro

(2012) Anna E van der Windt et al.   ARTHRITIS RESEARCH & THERAPY

Apc bridges Wnt/β-catenin and BMP signaling during osteoblast differentiation of KS483 cells

(2011) Razvan L. Miclea et al.   EXPERIMENTAL CELL RESEARCH

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

(2011) B.Y. Chan et al.   OSTEOARTHRITIS AND CARTILAGE

Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis

(2011) Rhian S Thomas et al.   ARTHRITIS RESEARCH & THERAPY

Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs

(2010) F. Corallini et al.   ANNALS OF THE RHEUMATIC DISEASES

Human articular chondrocytes secrete parathyroid hormone-related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis

(2010) J. Fischer et al.   ARTHRITIS AND RHEUMATISM

rBMP represses Wnt signaling and influences skeletal progenitor cell fate specification during bone repair

(2010) Steve Minear et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders

(2010) Rita Dreier   ARTHRITIS RESEARCH & THERAPY

Transplanted Chondrocytes Inhibit Endochondral Ossification Within Cartilage Repair Tissue

(2009) M. Blanke et al.   CALCIFIED TISSUE INTERNATIONAL

Mechanical Loading Regulates NFATc1 and β-Catenin Signaling through a GSK3β Control Node

(2009) Buer Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3

(2009) P Kaler et al.   ONCOGENE

Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction

(2008) Mei Zhu et al.   ARTHRITIS AND RHEUMATISM

Wnt signaling and osteoarthritis

(2008) Frank P. Luyten et al.   BONE

Regulation of Osteoarthritis Development by Wnt–β-catenin Signaling Through the Endochondral Ossification Process

(2008) Hiroshi Kawaguchi   JOURNAL OF BONE AND MINERAL RESEARCH

Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

(2008) Mei Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis

(2008) Massoud Daheshia et al.   JOURNAL OF RHEUMATOLOGY