The cancer metabolic reprogramming and immune response

Hyperactive PI3Kδ predisposes naive T cells to activation via aerobic glycolysis programs

(2020) Yanjun Jia et al.   Cellular & Molecular Immunology

Study of KIR gene expression at the mRNA level in specific donor-derived NK cells after allogeneic HSCT

(2020) Ying Li et al.   IMMUNOGENETICS

Cholesterol, Oxysterols and LXRs in Breast Cancer Pathophysiology

(2020) Hassan Nazih et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells

(2020) Boyoung Shin et al.   Cell Reports

Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions

(2020) Zixi Wang et al.   Frontiers in Immunology

Glutamine Metabolism and Its Role in Immunity, a Comprehensive Review

(2020) Ali Mujtaba Shah et al.   Animals

Diagnostic value of 18F-FDG-PET to predict the tumour immune status defined by tumoural PD-L1 and CD8+tumour-infiltrating lymphocytes in oral squamous cell carcinoma

(2020) Maria Togo et al.   BRITISH JOURNAL OF CANCER

In vitro 4-1BB stimulation promotes expansion of CD8+ tumor-infiltrating lymphocytes from various sarcoma subtypes

(2020) Morten Nielsen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

mTOR complex 2 is an integrator of cancer metabolism and epigenetics

(2020) Kenta Masui et al.   CANCER LETTERS

The Prognostic Role of High Blood Cholesterol in Advanced Cancer Patients Treated With Immune Checkpoint Inhibitors

(2020) Fabiana Perrone et al.   JOURNAL OF IMMUNOTHERAPY

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

(2020) Jonathan M. Ghergurovich et al.   Nature Chemical Biology

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

(2020) Franziska Püschel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostaglandin E Receptor 4 Antagonist in Cancer Immunotherapy: Mechanisms of Action

(2020) Yukinori Take et al.   Frontiers in Immunology

Metabolic Traits in Cutaneous Melanoma

(2020) Monica Neagu   Frontiers in Oncology

Metabolic Modulation of the Tumor Microenvironment Leads to Multiple Checkpoint Inhibition and Immune Cell Infiltration

(2020) David Kolb et al.   ACS Nano

Dietary Serine and Sulfate-Containing Amino Acids Related to the Nutritional Status of Selenium in Lactating Chinese Women

(2020) Feng Han et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells

(2020) J Amersfoort et al.   CARDIOVASCULAR RESEARCH

Chromatin accessibility of CD8 T cell differentiation and metabolic regulation

(2020) Haiyang Lu et al.   CELL BIOLOGY AND TOXICOLOGY

Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection

(2020) Maria L. Balmer et al.   Cell Metabolism

Metabolic signaling in T cells

(2020) Justin A. Shyer et al.   CELL RESEARCH

Metabolic crosstalk in the tumor microenvironment regulates antitumor immunosuppression and immunotherapy resisitance

(2020) Fang Wei et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Comprehensive assessment of multiple tryptophan metabolites as potential biomarkers for immune checkpoint inhibitors in patients with non-small cell lung cancer

(2020) M. Karayama et al.   Clinical & Translational Oncology

Low-Dose Metformin Reprograms the Tumor Immune Microenvironment in Human Esophageal Cancer: Results of a Phase II Clinical Trial

(2020) Shuhong Wang et al.   CLINICAL CANCER RESEARCH

Glutamine deprivation alters the origin and function of cancer cell exosomes

(2020) Shih‐Jung Fan et al.   EMBO JOURNAL

Targeting metabolism to reverse T‐cell exhaustion in chronic viral infections

(2020) John D. Sears et al.   IMMUNOLOGY

Regulation of cancer cell glucose metabolism is determinant for cancer cell fate after melatonin administration

(2020) Carmen Rodríguez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expression

(2020) Chenglai Xia et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma

(2020) Jiao Feng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Metformin and 2-Deoxyglucose Collaboratively Suppress Human CD4+ T Cell Effector Functions and Activation-Induced Metabolic Reprogramming

(2020) Stefanie Y. Tan et al.   JOURNAL OF IMMUNOLOGY

Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells

(2020) Harry J. Hurley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Frontline Science: Conversion of neutrophils into atypical Ly6G + SiglecF + immune cells with neurosupportive potential in olfactory neuroepithelium

(2020) Kei Ogawa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelet factor 4 enhances CD4 + T effector memory cell responses via Akt‐PGC1α‐TFAM signaling‐mediated mitochondrial biogenesis

(2020) Shuai Tan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

PGE2-HIF1α reciprocal induction regulates migration, phenotypic alteration and immunosuppressive capacity of macrophages in tumor microenvironment

(2020) Jayasree Saha et al.   LIFE SCIENCES

Neutrophil Extracellular Traps (NETs) and Damage-Associated Molecular Patterns (DAMPs): Two Potential Targets for COVID-19 Treatment

(2020) Sebastiano Cicco et al.   MEDIATORS OF INFLAMMATION

Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target

(2020) Beatriz Lapa et al.   MEDICAL ONCOLOGY

Effects of Porphyromonas gingivalis and Fusobacterium nucleatum on inflammasomes and their regulators in H400 cells

(2020) Kübra Aral et al.   Molecular Oral Microbiology

Dynamics in protein translation sustaining T cell preparedness

(2020) Tobias Wolf et al.   NATURE IMMUNOLOGY

MAP3K2 augments Th1 cell differentiation via IL-18 to promote T cell-mediated colitis

(2020) Ningbo Wu et al.   Science China-Life Sciences

A listeriolysin O subunit vaccine is protective against Listeria monocytogenes

(2020) Christopher C. Phelps et al.   VACCINE

Alteration of immunophenotype of human macrophages and monocytes after exposure to cigarette smoke

(2020) Camila Oliveira da Silva et al.   Scientific Reports

Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy

(2020) Luana Guerra et al.   Cell Reports

Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells

(2020) Garvin Dodard et al.   Cell Reports

cROSsing the Line: Between Beneficial and Harmful Effects of Reactive Oxygen Species in B-Cell Malignancies

(2020) Krzysztof Domka et al.   Frontiers in Immunology

Metabolomics: Impact of comorbidities and inflammation on sickness behaviors for individuals with chronic wounds

(2020) Junglyun Kim et al.   Advances in Wound Care

Glutaminase Inhibition on NSCLC Depends on Extracellular Alanine Exploitation

(2020) Elisa Caiola et al.   Cells

Metabolic Adaptations in Cancer Stem Cells

(2020) Umesh Prasad Yadav et al.   Frontiers in Oncology

Metabolic Reprogramming of Chemoresistant Cancer Cells and the Potential Significance of Metabolic Regulation in the Reversal of Cancer Chemoresistance

(2020) Xun Chen et al.   Metabolites

Network Approaches for Dissecting the Immune System

(2020) Hao Shi et al.   iScience

Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery

(2020) Binfan Chen et al.   BIOMATERIALS

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

(2020) Takumi Kobayashi et al.   BLOOD

Biodegradable pH-responsive micelles loaded with 8-hydroxyquinoline glycoconjugates for Warburg effect based tumor targeting

(2020) Adrian Domiński et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway

(2020) Yun Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

OxLDL-mediated immunologic memory in endothelial cells

(2020) Yahya Sohrabi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Metabolic regulation of T lymphocyte motility and migration

(2020) Juho Vuononvirta et al.   MOLECULAR ASPECTS OF MEDICINE

Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer

(2020) Allison S. Cohen et al.   Translational Oncology

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

(2020) Hao Wu et al.   Nature Communications

Mechanisms of T-Cell Exhaustion in Pancreatic Cancer

(2020) Didem Saka et al.   Cancers

Glucose induces metabolic reprogramming in neutrophils during type 2 diabetes to form constitutive extracellular traps and decreased responsiveness to lipopolysaccharides

(2020) Manjunath B. Joshi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Control of regulatory T cell homeostasis

(2020) Maja Buszko et al.   CURRENT OPINION IN IMMUNOLOGY

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

(2020) Weiqiang Lu et al.   EMBO Molecular Medicine

Effects of chitosan and oligochitosans on the phosphatidylinositol 3-kinase-AKT pathway in cancer therapy

(2020) Elaheh Amirani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment

(2019) Elena De Marchi et al.   ONCOGENE

NK cell metabolism

(2019) Clair M. Gardiner   JOURNAL OF LEUKOCYTE BIOLOGY

AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging

(2019) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Acetate Promotes T Cell Effector Function during Glucose Restriction

(2019) Jing Qiu et al.   Cell Reports

Metabolism as a key regulator in the pathogenesis of systemic lupus erythematosus

(2019) Yusuke Takeshima et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Concise Review: Metabolism and Gut Microbiota in Cancer Immunoediting, CD8/Treg Ratios, Immune Cell Homeostasis, and Cancer (Immuno)Therapy

(2019) Irina Kareva   STEM CELLS

High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation

(2019) Dunfang Zhang et al.   IMMUNITY

Metabolic Insight of Neutrophils in Health and Disease

(2019) Sachin Kumar et al.   Frontiers in Immunology

STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth

(2019) Chunyan Zhang et al.   Cell Metabolism

Effect of (R)‐salbutamol on the switch of phenotype and metabolic pattern in LPS‐induced macrophage cells

(2019) Shanping Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of Metabolic Reprogramming in Pulmonary Innate Immunity and Its Impact on Lung Diseases

(2019) Charalambos Michaeloudes et al.   Journal of Innate Immunity

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

(2019) Robert D. Leone et al.   SCIENCE

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

(2019) Tushar D Bhagat et al.   eLife

Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine

(2019) Sidney Behringer et al.   Metabolites

Porphyran isolated from Pyropia yezoensis inhibits lipopolysaccharide-induced activation of dendritic cells in mice

(2019) Yuhua Wang et al.   CARBOHYDRATE POLYMERS

Cyclooxygenase 2 Promotes Proliferation and Invasion in Ovarian Cancer Cells via the PGE2/NF-κB Pathway

(2019) Xiao Zhang et al.   CELL TRANSPLANTATION

Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

(2019) John-Michael Williford et al.   Science Advances

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

(2018) Jan P. Böttcher et al.   CELL

PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells

(2018) Wenting Zheng et al.   LEUKEMIA

A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects

(2018) Yuki Kagoya et al.   NATURE MEDICINE

Prostaglandin E 2 as a Regulator of Immunity to Pathogens

(2018) Giovanny J. Martínez-Colón et al.   PHARMACOLOGY & THERAPEUTICS

mTOR at the Transmitting and Receiving Ends in Tumor Immunity

(2018) Yakir Guri et al.   Frontiers in Immunology

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

(2018) Sara Ricciardi et al.   Cell Metabolism

Exosomes in HNSCC plasma as surrogate markers of tumour progression and immune competence

(2018) M.-N. Theodoraki et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Impact of Retinoic Acid on Immune Cells and Inflammatory Diseases

(2018) Luana de Mendonça Oliveira et al.   MEDIATORS OF INFLAMMATION

Combating herpesvirus encephalitis by potentiating a TLR3–mTORC2 axis

(2018) Ryota Sato et al.   NATURE IMMUNOLOGY

Activation of peroxisome proliferator-activated receptors α and δ synergizes with inflammatory signals to enhance adoptive cell therapy

(2018) Samuel D Saibil et al.   CANCER RESEARCH

Reinforce the antitumor activity of CD8+ T cells via glutamine restriction

(2018) Shogo Nabe et al.   CANCER SCIENCE

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

(2018) Marc O. Johnson et al.   CELL

Fatty Acid Oxidation in Macrophages and T Cells: Time for Reassessment?

(2018) Jan Van den Bossche et al.   Cell Metabolism

Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression

(2018) Na Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

(2018) Shane J. F. Cronin et al.   NATURE

Altered cancer metabolism in mechanisms of immunotherapy resistance

(2018) Rishab Ramapriyan et al.   PHARMACOLOGY & THERAPEUTICS

1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis

(2018) Yutao Yan et al.   Journal for ImmunoTherapy of Cancer

Gut microbiota and plasma metabolites associated with diabetes in women with, or at high risk for, HIV infection

(2018) Jee-Young Moon et al.   EBioMedicine

Modulation of Naive CD8 T Cell Response Features by Ligand Density, Affinity, and Continued Signaling via Internalized TCRs

(2017) Renu Balyan et al.   JOURNAL OF IMMUNOLOGY

The Adenosinergic System as a Therapeutic Target in the Vasculature: New Ligands and Challenges

(2017) Joana Sousa et al.   MOLECULES

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

(2017) Amy E. Baek et al.   Nature Communications

Glucose represses dendritic cell-induced T cell responses

(2017) Simon J. Lawless et al.   Nature Communications

Prostaglandin E2 As a Modulator of Viral Infections

(2017) Willem J. Sander et al.   Frontiers in Physiology

Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin

(2017) Tina Tang et al.   Scientific Reports

Targeted delivery of let-7b to reprogramme tumor-associated macrophages and tumor infiltrating dendritic cells for tumor rejection

(2016) Zhen Huang et al.   BIOMATERIALS

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

(2016) Roger Geiger et al.   CELL

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

(2016) Almut Brand et al.   Cell Metabolism

Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress

(2016) De Huang et al.   CELL RESEARCH

Safety of mTOR inhibitors in adult solid organ transplantation

(2016) Pedro Ventura-Aguiar et al.   Expert Opinion On Drug Safety

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

(2016) Omkar U. Kawalekar et al.   IMMUNITY

Tumor-associated mesenchymal stem cells inhibit naïve T cell expansion by blocking cysteine export from dendritic cells

(2016) Tithi Ghosh et al.   INTERNATIONAL JOURNAL OF CANCER

Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

(2016) R. Duffin et al.   SCIENCE

The role of dendritic cells in cancer

(2016) Morten Hansen et al.   Seminars in Immunopathology

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

(2016) Lianjun Zhang et al.   Cell Reports

Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma

(2016) Hao Liu et al.   Scientific Reports

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

(2015) Zachary T. Schug et al.   CANCER CELL

Nutrient Competition: A New Axis of Tumor Immunosuppression

(2015) Madhusudhanan Sukumar et al.   CELL

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions

(2015) Linchong Sun et al.   CELL RESEARCH

mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation

(2015) Kristen N. Pollizzi et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolic pathways promoting cancer cell survival and growth

(2015) Lindsey K. Boroughs et al.   NATURE CELL BIOLOGY

CREB pathway links PGE2 signaling with macrophage polarization

(2015) Bing Luan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

(2015) Nikolaos Patsoukis et al.   Nature Communications

Pasteurella multocida Toxin Manipulates T Cell Differentiation

(2015) Dagmar Hildebrand et al.   Frontiers in Microbiology

Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions

(2015) Clovis S. Palmer et al.   Frontiers in Immunology

Follow the ATP: Tumor Energy Production: A Perspective

(2014) Bryan Oronsky et al.   Anti-Cancer Agents in Medicinal Chemistry

Tumor cells and memory T cells converge at glycolysis

(2014) Swathi Karthikeyan et al.   CANCER BIOLOGY & THERAPY

Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics

(2014) J. G. Crompton et al.   CANCER RESEARCH

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

(2014) Tomoyuki Mashimo et al.   CELL

Adenosine 5′-Monophosphate–Activated Protein Kinase Regulates IL-10–Mediated Anti-Inflammatory Signaling Pathways in Macrophages

(2014) Yanfang Peipei Zhu et al.   JOURNAL OF IMMUNOLOGY

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Targeting Arginine-Dependent Cancers with Arginine-Degrading Enzymes: Opportunities and Challenges

(2014) Melissa M. Phillips et al.   Cancer Research and Treatment

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

(2013) Madhusudhanan Sukumar et al.   JOURNAL OF CLINICAL INVESTIGATION

The oxysterol–CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

(2013) Laura Raccosta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signaling through Purinergic Receptors for ATP Induces Human Cutaneous Innate and Adaptive Th17 Responses: Implications in the Pathogenesis of Psoriasis

(2013) M. E. Killeen et al.   JOURNAL OF IMMUNOLOGY

Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

(2013) Stefan Freigang et al.   NATURE IMMUNOLOGY

Fueling Immunity: Insights into Metabolism and Lymphocyte Function

(2013) E. L. Pearce et al.   SCIENCE

27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth

(2013) Qian Wu et al.   Cell Reports

Pro-tumorigenic function of autophagy in mammary oncogenesis

(2012) Huijun Wei et al.   Autophagy

Extracellular ATP Exerts Opposite Effects on Activated and Regulatory CD4+ T Cells via Purinergic P2 Receptor Activation

(2012) S. Trabanelli et al.   JOURNAL OF IMMUNOLOGY

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

The monocarboxylate transporter family-Structure and functional characterization

(2011) Andrew P. Halestrap   IUBMB LIFE

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

(2011) U. Schenk et al.   Science Signaling

RNAi-mediated CD73 suppression induces apoptosis and cell-cycle arrest in human breast cancer cells

(2010) Xiuling Zhi et al.   CANCER SCIENCE

Warburg phenotype in renal cell carcinoma: High expression of glucose-transporter 1 (GLUT-1) correlates with low CD8+ T-cell infiltration in the tumor

(2010) Katrin Singer et al.   INTERNATIONAL JOURNAL OF CANCER

Fatty Acids from Very Low-Density Lipoprotein Lipolysis Products Induce Lipid Droplet Accumulation in Human Monocytes

(2010) L. J. den Hartigh et al.   JOURNAL OF IMMUNOLOGY

Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation

(2010) E. L. Carr et al.   JOURNAL OF IMMUNOLOGY

Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes

(2010) Josef Ecker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Cancer Therapy by Skin Delivery of Indoleamine 2,3-Dioxygenase siRNA

(2009) M.-C. Yen et al.   CLINICAL CANCER RESEARCH

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Are side-chain oxidized oxysterols regulators also in vivo?

(2008) Ingemar Björkhem   JOURNAL OF LIPID RESEARCH