Exosomes in HNSCC plasma as surrogate markers of tumour progression and immune competence

Separation of plasma-derived exosomes into CD3(+) and CD3(-) fractions allows for association of immune cell and tumour cell markers with disease activity in HNSCC patients

(2018) M.-N. Theodoraki et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Biological mechanisms of immune escape and implications for immunotherapy in head and neck squamous cell carcinoma

(2017) Jennifer D. Moy et al.   EUROPEAN JOURNAL OF CANCER

Influence of photodynamic therapy on peripheral immune cell populations and cytokine concentrations in head and neck cancer

(2017) M.N. Theodoraki et al.   Photodiagnosis and Photodynamic Therapy

Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages – a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape

(2016) Itsaso Montalbán del Barrio et al.   Journal for ImmunoTherapy of Cancer

Immunology and Immunotherapy of Head and Neck Cancer

(2015) Robert L. Ferris   JOURNAL OF CLINICAL ONCOLOGY

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Human CD4+CD39+regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+exosomes or CD73+cells

(2014) P. J. Schuler et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor

(2014) Takumi Kumai et al.   Journal of Translational Medicine

Hostile, Hypoxia-A2-Adenosinergic Tumor Biology as the Next Barrier to Overcome for Tumor Immunologists

(2014) M. V. Sitkovsky et al.   Cancer Immunology Research

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4+T effector cells in patients with head and neck squamous cell carcinoma

(2012) Magis Mandapathil et al.   OncoImmunology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Immune Suppression in Head and Neck Cancers: A Review

(2011) Anaëlle Duray et al.   Clinical & Developmental Immunology

Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets

(2011) Patrick J. Schuler et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Distribution of immune cells in head and neck cancer: CD8+ T-cells and CD20+B-cells in metastatic lymph nodes are associated with favourable outcome in patients with oro- and hypopharyngeal carcinoma

(2009) Dominik Pretscher et al.   BMC CANCER

Adenosine deaminase enhances T-cell response elicited by dendritic cells loaded with inactivated HIV

(2009) Núria Climent et al.   IMMUNOLOGY AND CELL BIOLOGY

Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25highFOXP3+Regulatory T Cells

(2009) Magis Mandapathil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Adenosinergic Immunosuppression: Tumor Protection by T Regulatory Cells and Cancerous Tissue Hypoxia

(2008) M. V. Sitkovsky et al.   CLINICAL CANCER RESEARCH