Glucose induces metabolic reprogramming in neutrophils during type 2 diabetes to form constitutive extracellular traps and decreased responsiveness to lipopolysaccharides

Neutrophil Metabolic Shift during Their Lifecycle: Impact on Their Survival and Activation

(2020) Louise Injarabian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycolysis – a key player in the inflammatory response

(2020) Gonzalo Soto‐Heredero et al.   FEBS Journal

Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency

(2019) Maria Veiga-da-Cunha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperglycemia Induces Neutrophil Extracellular Traps Formation Through an NADPH Oxidase-Dependent Pathway in Diabetic Retinopathy

(2019) Luoziyi Wang et al.   Frontiers in Immunology

Impact of advanced glycation end products (AGEs) signaling in coronary artery disease

(2019) Marinos Kosmopoulos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice

(2019) Taylor S. Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic analysis of peripheral blood polymorphonuclear cells (PBMCs) reveals alteration of neutrophil extracellular trap (NET) components in uncontrolled diabetes

(2019) J. Soongsathitanon et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Metabolite Repair Enzymes Control Metabolic Damage in Glycolysis

(2019) Guido T. Bommer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Metabolic Insight of Neutrophils in Health and Disease

(2019) Sachin Kumar et al.   Frontiers in Immunology

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

(2018) Pedro Escoll et al.   FEBS Journal

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

NETosis before and after Hyperglycemic Control in Type 2 Diabetes Mellitus Patients

(2017) Agostina Carestia et al.   PLoS One

Reactive Oxygen Species and Neutrophil Function

(2016) Christine C. Winterbourn et al.   Annual Review of Biochemistry

Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis

(2016) Marta Guasch-Ferré et al.   DIABETES CARE

Neutrophil extracellular traps — the dark side of neutrophils

(2016) Ole E. Sørensen et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Circulating Neutrophil Extracellular Trap Levels in Well-Controlled Type 2 Diabetes and Pathway Involved in Their Formation Induced by High-Dose Glucose

(2016) Arina Miyoshi et al.   PATHOBIOLOGY

Metabolic reprogramming & inflammation: Fuelling the host response to pathogens

(2016) Laura E. Gleeson et al.   SEMINARS IN IMMUNOLOGY

Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical Application

(2016) Matthias S. Klein et al.   Journal of Diabetes Research

Platelets: New Bricks in the Building of Neutrophil Extracellular Traps

(2016) Agostina Carestia et al.   Frontiers in Immunology

Elevated homocysteine levels in type 2 diabetes induce constitutive neutrophil extracellular traps

(2016) Manjunath B Joshi et al.   Scientific Reports

Metabolic requirements for neutrophil extracellular traps formation

(2015) Oscar Rodríguez-Espinosa et al.   IMMUNOLOGY

A Metabolic Shift toward Pentose Phosphate Pathway Is Necessary for Amyloid Fibril- and Phorbol 12-Myristate 13-Acetate-induced Neutrophil Extracellular Trap (NET) Formation

(2015) Estefania P. Azevedo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mediators and molecular pathways involved in the regulation of neutrophil extracellular trap formation mediated by activated platelets

(2015) Agostina Carestia et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

(2015) Siu Ling Wong et al.   NATURE MEDICINE

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil-macrophage communication in inflammation and atherosclerosis

(2015) M. Nahrendorf et al.   SCIENCE

NETosis is induced by high glucose and associated with type 2 diabetes

(2014) Lisa Menegazzo et al.   ACTA DIABETOLOGICA

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation

(2013) Manjunath B. Joshi et al.   FEBS LETTERS

Glutathione reductase is essential for host defense against bacterial infection

(2013) Jing Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metabolic Signature Shift in Type 2 Diabetes Mellitus Revealed by Mass Spectrometry-based Metabolomics

(2013) Fengguo Xu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Host Susceptibility Factors to Bacterial Infections in Type 2 Diabetes

(2013) Yunn-Hwen Gan   PLoS Pathogens

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Glutathione Reductase Facilitates Host Defense by Sustaining Phagocytic Oxidative Burst and Promoting the Development of Neutrophil Extracellular Traps

(2012) J. Yan et al.   JOURNAL OF IMMUNOLOGY

Novel biomarkers for pre-diabetes identified by metabolomics

(2012) Rui Wang-Sattler et al.   Molecular Systems Biology

Aldose Reductase, Oxidative Stress, and Diabetic Mellitus

(2012) Wai Ho Tang et al.   Frontiers in Pharmacology

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Novel Role for Aldose Reductase in Mediating Acute Inflammatory Responses in the Lung

(2009) T. M. Ravindranath et al.   JOURNAL OF IMMUNOLOGY

Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

(2009) A. B. Guimaraes-Costa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA