Neuronal Dopamine D3 Receptors: Translational Implications for Preclinical Research and CNS Disorders
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neuronal Dopamine D3 Receptors: Translational Implications for Preclinical Research and CNS Disorders
Authors
Keywords
-
Journal
Biomolecules
Volume 11, Issue 1, Pages 104
Publisher
MDPI AG
Online
2021-01-15
DOI
10.3390/biom11010104
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Characterising Inter-helical Interactions of G Protein-Coupled Receptors with the Fragment Molecular Orbital Method
- (2020) Alexander Heifetz et al. Journal of Chemical Theory and Computation
- Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands
- (2020) Luyu Fan et al. Nature Communications
- Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism
- (2020) J Robert Lane et al. eLife
- Expression of Melatonin and Dopamine D3 Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension
- (2020) Irene Reyes-Resina et al. Cells
- Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation
- (2020) Rita Maria Concetta Di Martino et al. ChemMedChem
- Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist
- (2020) Amy E. Moritz et al. JOURNAL OF MEDICINAL CHEMISTRY
- Preclinical pharmacology of [2-(3-fluoro-5-methanesulfonylphenoxy)ethyl](propyl)amine (IRL790), a novel dopamine transmission modulator for the treatment of motor and psychiatric complications in Parkinson’s disease
- (2020) Susanna Waters et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A novel molecular mechanism responsible for phosphorylation-independent desensitization of G protein-coupled receptors exemplified by the dopamine D3 receptor
- (2020) Mei Zheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment
- (2020) Tibor Stark et al. BIOCHEMICAL PHARMACOLOGY
- Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane
- (2020) Jie Yin et al. NATURE
- Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia
- (2020) Jean Claude Martel et al. Frontiers in Pharmacology
- The Long-Acting D3 Partial Agonist MC-25-41 Attenuates Motivation for Cocaine in Sprague-Dawley Rats
- (2020) Gregory L. Powell et al. Biomolecules
- Evidence for a Stereoselective Mechanism for Bitopic Activity by Extended-Length Antagonists of the D3 Dopamine Receptor
- (2020) Amy E. Moritz et al. ACS Chemical Neuroscience
- Pharmacology profile of F17464, a dopamine D3 receptor preferential antagonist
- (2020) Cristina Cosi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Dual-acting agents for improving cognition and real-world function in Alzheimer’s disease: Focus on 5-HT6 and D3 receptors as hubs
- (2020) Mark J. Millan et al. NEUROPHARMACOLOGY
- Association of dopamine D2/3 receptor binding potential measured using PET and [11C]-(+)-PHNO with post-mortem DRD2/3 gene expression in the human brain
- (2020) Arkadiusz Komorowski et al. NEUROIMAGE
- Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms
- (2019) Robert A. McCutcheon et al. TRENDS IN NEUROSCIENCES
- Randomized, double-blind, placebo-controlled study of F17464, a preferential D3 antagonist, in the treatment of acute exacerbation of schizophrenia
- (2019) Istvan Bitter et al. NEUROPSYCHOPHARMACOLOGY
- Biased G Protein-Independent Signaling of Dopamine D1-D3 Receptor Heteromers in the Nucleus Accumbens
- (2019) Xavier Guitart et al. MOLECULAR NEUROBIOLOGY
- Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study
- (2019) Willie Earley et al. AMERICAN JOURNAL OF PSYCHIATRY
- Functional lateralization in the prefrontal cortex of dopaminergic modulation of memory consolidation
- (2019) Mariusz Papp et al. BEHAVIOURAL PHARMACOLOGY
- The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors
- (2019) Wolfgang Fleischhacker et al. EUROPEAN PSYCHIATRY
- Biased signaling agonist of dopamine D3 receptor induces receptor internalization independent of β-arrestin recruitment
- (2019) Wei Xu et al. PHARMACOLOGICAL RESEARCH
- Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands
- (2019) Peng-Jen Chen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The EMBL-EBI search and sequence analysis tools APIs in 2019
- (2019) Fábio Madeira et al. NUCLEIC ACIDS RESEARCH
- Dopamine Receptor D3 Expression Is Altered in CD4+ T-Cells From Parkinson's Disease Patients and Its Pharmacologic Inhibition Attenuates the Motor Impairment in a Mouse Model
- (2019) Daniela Elgueta et al. Frontiers in Immunology
- Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole
- (2019) Carmen Klein Herenbrink et al. ACS Chemical Biology
- 2016 Philip S. Portoghese Medicinal Chemistry Lectureship: Designing Bivalent or Bitopic Molecules for G-Protein Coupled Receptors. The Whole Is Greater Than the Sum of Its Parts
- (2019) Amy Hauck Newman et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
- (2019) Mei Huang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans
- (2019) G. M. Leggio et al. MOLECULAR PSYCHIATRY
- Nicotine prevents alpha-synuclein accumulation in mouse and human iPSC-derived dopaminergic neurons through activation of the dopamine D3- acetylcholine nicotinic receptor heteromer
- (2019) Federica Bono et al. NEUROBIOLOGY OF DISEASE
- Blonanserin ameliorates social deficit through dopamine-D3 receptor antagonism in mice administered phencyclidine as an animal model of schizophrenia
- (2019) Saori Takeuchi et al. NEUROCHEMISTRY INTERNATIONAL
- Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine
- (2019) Béla Kiss et al. Drug Design Development and Therapy
- Efficacy and safety of cariprazine in bipolar I depression: A double‐blind, placebo‐controlled phase 3 study
- (2019) Willie R. Earley et al. BIPOLAR DISORDERS
- The novel antipsychotic cariprazine stabilizes gamma oscillations in rat hippocampal slices
- (2019) Maria A. Meier et al. BRITISH JOURNAL OF PHARMACOLOGY
- Binding of the D3-preferring antipsychotic candidate F17464 to dopamine D3 and D2 receptors: a PET study in healthy subjects with [11C]-(+)-PHNO
- (2019) Mark Slifstein et al. PSYCHOPHARMACOLOGY
- Is There a Role for GPCR Agonist Radiotracers in PET Neuroimaging?
- (2019) Matthieu Colom et al. Frontiers in Molecular Neuroscience
- Dopamine D3 receptor: A neglected participant in Parkinson Disease pathogenesis and treatment?
- (2019) Pengfei Yang et al. AGEING RESEARCH REVIEWS
- Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine
- (2019) Meagan L. Auger et al. NEUROPHARMACOLOGY
- A positron emission tomography occupancy study of brexpiprazole at dopamine D2 and D3 and serotonin 5-HT1A and 5-HT2A receptors, and serotonin reuptake transporters in subjects with schizophrenia
- (2019) Ragy R. Girgis et al. NEUROPSYCHOPHARMACOLOGY
- Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry
- (2018) Fernando Caravaggio et al. EXPERIMENTAL EYE RESEARCH
- Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction
- (2018) Sora Shin et al. NEURON
- Selectivity of probes for PET imaging of dopamine D3 receptors
- (2018) Robert K. Doot et al. NEUROSCIENCE LETTERS
- Effects of cariprazine on extracellular levels of glutamate, GABA, dopamine, noradrenaline and serotonin in the medial prefrontal cortex in the rat phencyclidine model of schizophrenia studied by microdialysis and simultaneous recordings of locomotor activity
- (2018) Jan Kehr et al. PSYCHOPHARMACOLOGY
- The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task
- (2018) Samuel A. Barnes et al. PSYCHOPHARMACOLOGY
- Molecular Dynamics Simulation of Biased Agonists at the Dopamine D2 Receptor Suggests the Mechanism of Receptor Functional Selectivity
- (2018) David Montgomery et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone
- (2018) Sheng Wang et al. NATURE
- New Dopamine D3-Selective Receptor Ligands Containing a 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol Motif
- (2018) Satishkumar Gadhiya et al. ACS Medicinal Chemistry Letters
- Binding kinetics of cariprazine and aripiprazole at the dopamine D3 receptor
- (2018) Annika Frank et al. Scientific Reports
- Dopamine Agonists for Pituitary Adenomas
- (2018) Odelia Cooper et al. Frontiers in Endocrinology
- Differential Effects of D1 and D2 Dopamine Agonists on Memory, Motivation, Learning and Response Time in Non-human Primates
- (2018) Robert A Marino et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist
- (2018) Matthieu Masureel et al. Nature Chemical Biology
- Occupancy of dopamine D2 and D3 receptors by a novel D3 partial agonist BP1.4979: a [11C]-(+)-PHNO PET study in humans
- (2018) Patricia Di Ciano et al. NEUROPSYCHOPHARMACOLOGY
- UniProt: a worldwide hub of protein knowledge
- (2018) NUCLEIC ACIDS RESEARCH
- Dopamine D3 and acetylcholine nicotinic receptor heteromerization in midbrain dopamine neurons: Relevance for neuroplasticity
- (2017) Leonardo Bontempi et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Cariprazine Exhibits Anxiolytic and Dopamine D3 Receptor-Dependent Antidepressant Effects in the Chronic Stress Model
- (2017) Vanja Duric et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Dopamine System Dysregulation in Major Depressive Disorders
- (2017) Pauline Belujon et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor
- (2017) Mayako Michino et al. JOURNAL OF MEDICINAL CHEMISTRY
- Highly Selective Dopamine D3 Receptor Antagonists with Arylated Diazaspiro Alkane Cores
- (2017) Sean W. Reilly et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R)
- (2017) Vivek Kumar et al. JOURNAL OF MEDICINAL CHEMISTRY
- D3 Receptors Regulate Excitability in a Unique Class of Prefrontal Pyramidal Cells
- (2017) Rebecca L. Clarkson et al. JOURNAL OF NEUROSCIENCE
- Cariprazine versus risperidone monotherapy for treatment of predominant negative symptoms in patients with schizophrenia: a randomised, double-blind, controlled trial
- (2017) György Németh et al. LANCET
- Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs
- (2017) John D McCorvy et al. Nature Chemical Biology
- Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens
- (2017) Yolanda Mateo et al. NEURON
- The novel dopamine D3 receptor antagonists/partial agonists CAB2-015 and BAK4-54 inhibit oxycodone-taking and oxycodone-seeking behavior in rats
- (2017) Zhi-Bing You et al. NEUROPHARMACOLOGY
- GPCRdb in 2018: adding GPCR structure models and ligands
- (2017) Gáspár Pándy-Szekeres et al. NUCLEIC ACIDS RESEARCH
- The antipsychotic-like effects in rodents of YQA31 involve dopamine D3 and 5-HT1A receptor
- (2017) Hong-Yan Gou et al. Pharmacological Reports
- Dopaminergic mechanisms in memory consolidation and antidepressant reversal of a chronic mild stress-induced cognitive impairment`
- (2017) Mariusz Papp et al. PSYCHOPHARMACOLOGY
- Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2 -deficient mice
- (2017) Aslihan Selimbeyoglu et al. Science Translational Medicine
- Cortical high gamma network oscillations and connectivity: a translational index for antipsychotics to normalize aberrant neurophysiological activity
- (2017) A. Ahnaou et al. Translational Psychiatry
- Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade
- (2017) Sebastiano Alfio Torrisi et al. Frontiers in Pharmacology
- Selective Enhancement of Dopamine Release in the Ventral Pallidum of Methamphetamine-Sensitized Mice
- (2016) Kristen A. Stout et al. ACS Chemical Neuroscience
- Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects
- (2016) Travis T. Wager et al. ACS Chemical Neuroscience
- Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists
- (2016) Wei Xu et al. ACS Chemical Neuroscience
- An 8-Week Randomized, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Cariprazine in Patients With Bipolar I Depression
- (2016) Suresh Durgam et al. AMERICAN JOURNAL OF PSYCHIATRY
- The atypical antipsychotic blonanserin reverses (+)-PD-128907- and ketamine-induced deficit in executive function in common marmosets
- (2016) Manato Kotani et al. BEHAVIOURAL BRAIN RESEARCH
- GPCR Dynamics: Structures in Motion
- (2016) Naomi R. Latorraca et al. CHEMICAL REVIEWS
- The role of the dopamine D1 receptor in social cognition: studies using a novel genetic rat model
- (2016) Judith R. Homberg et al. Disease Models & Mechanisms
- The dopamine D3 receptor, a quarter century later
- (2016) Pierre Sokoloff et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Effects of a potential D3/5-HT1A antipsychotic compound, F17464, in rat behavioural models of cognitive and negative symptoms of schizophrenia
- (2016) A. Auclair et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology
- (2016) Jo C. Neill et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- The dopamine D 3 -preferring D 2 /D 3 dopamine receptor partial agonist, cariprazine, reverses behavioural changes in a rat neurodevelopmental model for schizophrenia
- (2016) David J.G. Watson et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Targeting the dopamine D3 receptor: an overview of drug design strategies
- (2016) Antoni Cortés et al. Expert Opinion on Drug Discovery
- Efficacy and Safety of Adjunctive Cariprazine in Inadequate Responders to Antidepressants
- (2016) Suresh Durgam et al. JOURNAL OF CLINICAL PSYCHIATRY
- Dopamine Receptor D3 Signaling on CD4+T Cells Favors Th1- and Th17-Mediated Immunity
- (2016) Francisco Contreras et al. JOURNAL OF IMMUNOLOGY
- Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment
- (2016) Vivek Kumar et al. JOURNAL OF MEDICINAL CHEMISTRY
- Current drug treatments targeting dopamine D3 receptor
- (2016) Gian Marco Leggio et al. PHARMACOLOGY & THERAPEUTICS
- Effect of chronic social defeat stress on behaviors and dopamine receptor in adult mice
- (2016) Guang-Biao Huang et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Long-term cariprazine treatment for the prevention of relapse in patients with schizophrenia: A randomized, double-blind, placebo-controlled trial
- (2016) Suresh Durgam et al. SCHIZOPHRENIA RESEARCH
- PET radiotracer development for imaging high-affinity state of dopamine D2 and D3 receptors: Binding studies of fluorine-18 labeled aminotetralins in rodents
- (2016) Jogeshwar Mukherjee et al. SYNAPSE
- β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment
- (2016) Sungchil Yang et al. Cell Reports
- Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases
- (2016) Samuele Maramai et al. Frontiers in Neuroscience
- Dopamine D3 Receptors Inhibit Hippocampal Gamma Oscillations by Disturbing CA3 Pyramidal Cell Firing Synchrony
- (2016) Clément E. Lemercier et al. Frontiers in Pharmacology
- Immunomodulatory Effects Mediated by Dopamine
- (2016) Rodrigo Arreola et al. Journal of Immunology Research
- Alterations in Cortical Network Oscillations and Parvalbumin Neurons in Schizophrenia
- (2015) Guillermo Gonzalez-Burgos et al. BIOLOGICAL PSYCHIATRY
- Bitropic D3 Dopamine Receptor Selective Compounds s Potential Antipsychotics
- (2015) Robert Luedtke et al. CURRENT PHARMACEUTICAL DESIGN
- Dopamine D3 receptor agonists as pharmacological tools
- (2015) S. Kassel et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam
- (2015) Gian Marco Leggio et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Pharmacological targeting of dopamine D3 receptors: Possible clinical applications of selective drugs
- (2015) Emilio Merlo Pich et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Cariprazine in the treatment of acute mania in bipolar I disorder: A double-blind, placebo-controlled, Phase III trial
- (2015) Gary S. Sachs et al. JOURNAL OF AFFECTIVE DISORDERS
- Cariprazine in Acute Exacerbation of Schizophrenia
- (2015) Suresh Durgam et al. JOURNAL OF CLINICAL PSYCHIATRY
- Efficacy and Safety of Cariprazine in Acute Exacerbation of Schizophrenia
- (2015) John M. Kane et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Dopamine receptors D3 and D5 regulate CD4+T-cell activation and differentiation by modulating ERK activation and cAMP production
- (2015) Dafne Franz et al. JOURNAL OF NEUROIMMUNOLOGY
- Behavioral effects of D3 receptor inhibition and 5-HT4 receptor activation on animals undergoing chronic cannabinoid exposure during adolescence
- (2015) Oualid Abboussi et al. METABOLIC BRAIN DISEASE
- Effects of ziprasidone, SCH23390 and SB277011 on spatial memory in the Morris water maze test in naive and MK-801 treated mice
- (2015) Pelin Tanyeri et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Antipsychotic binding to the dopamine-3 receptor in humans: A PET study with [11C]-(+)-PHNO
- (2015) Ragy R. Girgis et al. SCHIZOPHRENIA RESEARCH
- Dopamine receptor D3 deficiency results in chronic depression and anxiety
- (2014) Rodrigo Moraga-Amaro et al. BEHAVIOURAL BRAIN RESEARCH
- The efficacy and tolerability of cariprazine in acute mania associated with bipolar I disorder: a phase II trial
- (2014) Suresh Durgam et al. BIPOLAR DISORDERS
- Dopamine receptors - IUPHAR Review 13
- (2014) Jean-Martin Beaulieu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Glycogen Synthase Kinase-3 as a Therapeutic Target for Cognitive Dysfunction in Neuropsychiatric Disorders
- (2014) Olivia O’Leary et al. CNS DRUGS
- Efficacy and Safety of Low- and High-Dose Cariprazine in Acute and Mixed Mania Associated With Bipolar I Disorder
- (2014) Joseph R. Calabrese et al. JOURNAL OF CLINICAL PSYCHIATRY
- An evaluation of the safety and efficacy of cariprazine in patients with acute exacerbation of schizophrenia: A phase II, randomized clinical trial
- (2014) Suresh Durgam et al. SCHIZOPHRENIA RESEARCH
- Recent methods for measuring dopamine D3 receptor occupancy in vivo: importance for drug development
- (2014) Bernard Le Foll et al. Frontiers in Pharmacology
- Effects of a dopamine D1 agonist on ketamine-induced spatial working memory dysfunction in common marmosets
- (2013) Tomokazu Nakako et al. BEHAVIOURAL BRAIN RESEARCH
- Effects of immobilization stress on emotional behaviors in dopamine D3 receptor knockout mice
- (2013) Bo Xing et al. BEHAVIOURAL BRAIN RESEARCH
- Selective Overexpression of Dopamine D3 Receptors in the Striatum Disrupts Motivation but not Cognition
- (2013) Eleanor H. Simpson et al. BIOLOGICAL PSYCHIATRY
- Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3receptors
- (2013) C Min et al. BRITISH JOURNAL OF PHARMACOLOGY
- Dopamine D3 receptor as a new pharmacological target for the treatment of depression
- (2013) Gian Marco Leggio et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The potential role of dopamine D3 receptor neurotransmission in cognition
- (2013) Shinichiro Nakajima et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Transient and rapid activation of Akt/GSK-3β and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens
- (2013) Marie-Josèphe Salles et al. JOURNAL OF NEUROCHEMISTRY
- Minireview: Dopaminergic Regulation of Insulin Secretion from the Pancreatic Islet
- (2013) Alessandro Ustione et al. MOLECULAR ENDOCRINOLOGY
- Rationale in support of the use of selective dopamine D3 receptor antagonists for the pharmacotherapeutic management of substance use disorders
- (2013) Christian Heidbreder NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Dopamine D3 receptor antagonism—still a therapeutic option for the treatment of schizophrenia
- (2013) Gerhard Gross et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Direct and indirect interactions of the dopamine D3 receptor with glutamate pathways: implications for the treatment of schizophrenia
- (2013) Pierre Sokoloff et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Profile of blonanserin for the treatment of schizophrenia
- (2013) Tomomi Tenjin et al. Neuropsychiatric Disease and Treatment
- Medication discovery for addiction: Translating the dopamine D3 receptor hypothesis
- (2012) Amy Hauck Newman et al. BIOCHEMICAL PHARMACOLOGY
- First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3and D3receptors
- (2012) Steffen B Schulz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Current State of Agonist Radioligands for Imaging of Brain Dopamine D2/D3 Receptors In Vivo with Positron Emission Tomography
- (2012) Sjoerd J. Finnema et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Indirect Comparisons of Adverse Events and Dropout Rates in Early Parkinson's Disease Trials of Pramipexole, Ropinirole, and Rasagiline
- (2012) Francisco J. Zagmutt et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Dopamine Synthesis and D3 Receptor Activation in Pancreatic β-Cells Regulates Insulin Secretion and Intracellular [Ca2+] Oscillations
- (2012) Alessandro Ustione et al. MOLECULAR ENDOCRINOLOGY
- Occupancy of Brain Dopamine D3 Receptors and Drug Craving: A Translational Approach
- (2012) Manolo Mugnaini et al. NEUROPSYCHOPHARMACOLOGY
- Multiple signaling routes involved in the regulation of adenylyl cyclase and extracellular regulated kinase by dopamine D2 and D3 receptors
- (2012) Mingli Jin et al. PHARMACOLOGICAL RESEARCH
- Cariprazine, a dopamine D3-receptor-preferring partial agonist, blocks phencyclidine-induced impairments of working memory, attention set-shifting, and recognition memory in the mouse
- (2012) Ross Zimnisky et al. PSYCHOPHARMACOLOGY
- Poster #16 CARIPRAZINE, A D3/D2 DOPAMINE RECEPTOR PARTIAL AGONIST ANTIPSYCHOTIC, DISPLAYS GREATER D3 RECEPTOR OCCUPANCY IN VIVO COMPARED WITH OTHER ANTIPSYCHOTICS
- (2012) Bela Kiss et al. SCHIZOPHRENIA RESEARCH
- Inverted-U–Shaped Dopamine Actions on Human Working Memory and Cognitive Control
- (2011) Roshan Cools et al. BIOLOGICAL PSYCHIATRY
- Blockade of dopamine D3 but not D2 receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment
- (2011) David J. G. Watson et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- A Double-Blind, Randomized, Placebo-Controlled Study of the Dopamine D3 Receptor Antagonist ABT-925 in Patients With Acute Schizophrenia
- (2011) Laura Redden et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- D2-like dopamine receptors differentially regulate unitary IPSCs depending on presynaptic GABAergic neuron subtypes in rat nucleus accumbens shell
- (2011) Shuntaro Kohnomi et al. JOURNAL OF NEUROPHYSIOLOGY
- Long-term safety and efficacy of rotigotine transdermal patch for moderate-to-severe idiopathic restless legs syndrome: a 5-year open-label extension study
- (2011) Wolfgang Oertel et al. LANCET NEUROLOGY
- Neocortical excitation/inhibition balance in information processing and social dysfunction
- (2011) Ofer Yizhar et al. NATURE
- Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents
- (2011) István Gyertyán et al. NEUROCHEMISTRY INTERNATIONAL
- Selective Blockade of Dopamine D3 Receptors Enhances while D2 Receptor Antagonism Impairs Social Novelty Discrimination and Novel Object Recognition in Rats: A Key Role for the Prefrontal Cortex
- (2011) David JG Watson et al. NEUROPSYCHOPHARMACOLOGY
- Dopamine D3-Like Receptors Modulate Anxiety-Like Behavior and Regulate GABAergic Transmission in the Rat Lateral/Basolateral Amygdala
- (2011) Marvin R Diaz et al. NEUROPSYCHOPHARMACOLOGY
- Effects of antipsychotics on D3 receptors: A clinical PET study in first episode antipsychotic naive patients with schizophrenia using [11C]-(+)-PHNO
- (2011) Romina Mizrahi et al. SCHIZOPHRENIA RESEARCH
- Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11C]PHNO, and a Selective D3 Receptor Antagonist
- (2010) Graham Searle et al. BIOLOGICAL PSYCHIATRY
- Dopamine Receptor Agonists for the Treatment of Early or Advanced Parkinsonʼs Disease
- (2010) Santiago Perez-Lloret et al. CNS DRUGS
- The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures
- (2010) Mark J. Millan et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex
- (2010) H. E. Covington et al. JOURNAL OF NEUROSCIENCE
- Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile
- (2010) B. Kiss et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Abnormal neural oscillations and synchrony in schizophrenia
- (2010) Peter J. Uhlhaas et al. NATURE REVIEWS NEUROSCIENCE
- In vitro hippocampal gamma oscillation power as an index of in vivo CA3 gamma oscillation strength and spatial reference memory
- (2010) Cheng B. Lu et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy
- (2010) Andri C. Tziortzi et al. NEUROIMAGE
- Dopaminergic Modulation of Axon Initial Segment Calcium Channels Regulates Action Potential Initiation
- (2010) Kevin J. Bender et al. NEURON
- The Antipsychotics Olanzapine, Risperidone, Clozapine and Haloperidol Are D2-Selective Ex Vivo but Not In Vitro
- (2010) Patrick N McCormick et al. NEUROPSYCHOPHARMACOLOGY
- Influence of dopamine D3 receptor knockout on age-related decline of spatial memory
- (2010) Bo Xing et al. NEUROSCIENCE LETTERS
- Enhanced cognitive performance of dopamine D3 receptor “knock-out” mice in the step-through passive-avoidance test: Assessing the role of the endocannabinoid/endovanilloid systems
- (2010) Vincenzo Micale et al. PHARMACOLOGICAL RESEARCH
- Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist
- (2010) E. Y. T. Chien et al. SCIENCE
- The Effect of Antipsychotics on the High-Affinity State of D2 and D3 Receptors
- (2009) Ariel Graff-Guerrero et al. ARCHIVES OF GENERAL PSYCHIATRY
- Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925
- (2009) Ariel Graff-Guerrero et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- 1,2,4-Triazolyl Azabicyclo[3.1.0]hexanes: A New Series of Potent and Selective Dopamine D3Receptor Antagonists
- (2009) Fabrizio Micheli et al. JOURNAL OF MEDICINAL CHEMISTRY
- The structure and function of G-protein-coupled receptors
- (2009) Daniel M. Rosenbaum et al. NATURE
- Driving fast-spiking cells induces gamma rhythm and controls sensory responses
- (2009) Jessica A. Cardin et al. NATURE
- The Model- and the Data-Gamma
- (2009) Pascal Fries NEURON
- In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice
- (2009) Eugenii A. Rabiner et al. SYNAPSE
- Rotigotine Transdermal Patch
- (2008) Claudine M Baldwin et al. CNS DRUGS
- Blockade of dopamine D3 receptors in frontal cortex, but not in sub-cortical structures, enhances social recognition in rats: Similar actions of D1 receptor agonists, but not of D2 antagonists
- (2008) Florence Loiseau et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Postsynaptic dopamine D3 receptor modulation of evoked IPSCs via GABAA receptor endocytosis in rat hippocampus
- (2008) Jarod Swant et al. HIPPOCAMPUS
- G Protein Coupling and Ligand Selectivity of the D2L and D3 Dopamine Receptors
- (2008) J. R. Lane et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Asenapine: a novel psychopharmacologic agent with a unique human receptor signature
- (2008) M. Shahid et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Reciprocal Regulation of Dopamine D1 and D3 Receptor Function and Trafficking by Heterodimerization
- (2008) C. Fiorentini et al. MOLECULAR PHARMACOLOGY
- The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson’s disease
- (2008) Dieter Scheller et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15
- (2008) Béla Kiss et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Effect of D3 dopamine receptors blockade on the cognitive effects of angiotensin IV in rats
- (2008) Jan J. Braszko et al. NEUROPEPTIDES
- The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats
- (2008) Xiao-Qing Peng et al. NEUROPHARMACOLOGY
- Dopamine receptor 3 (D3) knockout mice show regular emotional behaviour
- (2008) S CHOURBAJI et al. PHARMACOLOGICAL RESEARCH
- Dopamine D2/D3 receptor agonist quinpirole impairs spatial reversal learning in rats: investigation of D3 receptor involvement in persistent behavior
- (2008) Vasileios Boulougouris et al. PSYCHOPHARMACOLOGY
- Efficacy and safety of bifeprunox in patients with an acute exacerbation of schizophrenia: results from a randomized, double-blind, placebo-controlled, multicenter, dose-finding study
- (2008) Daniel E. Casey et al. PSYCHOPHARMACOLOGY
- Brain region binding of the D2/3 agonist [11C]-(+)-PHNO and the D2/3 antagonist [11C]raclopride in healthy humans
- (2007) Ariel Graff-Guerrero et al. HUMAN BRAIN MAPPING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started