Nicotine prevents alpha-synuclein accumulation in mouse and human iPSC-derived dopaminergic neurons through activation of the dopamine D3- acetylcholine nicotinic receptor heteromer

Title
Nicotine prevents alpha-synuclein accumulation in mouse and human iPSC-derived dopaminergic neurons through activation of the dopamine D3- acetylcholine nicotinic receptor heteromer
Authors
Keywords
Alpha-synuclein, Ubiquitin-proteasome system (UPS), Nicotine, Dopamine D3 receptor, Heteromerization, Nicotinic receptor, Human induced pluripotent stem cell (hiPSC), Neuroprotection, Proximity Ligation Assay (PLA)
Journal
NEUROBIOLOGY OF DISEASE
Volume 129, Issue -, Pages 1-12
Publisher
Elsevier BV
Online
2019-05-01
DOI
10.1016/j.nbd.2019.04.017

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