The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task

Neonatal Prefrontal Inactivation Results in Reversed Dopaminergic Responses in the Shell Subregion of the Nucleus Accumbens to NMDA Antagonists

(2016) Tiphaine Pouvreau et al.   ACS Chemical Neuroscience

Dopamine D1 receptor activation improves PCP-induced performance disruption in the 5C-CPT by reducing inappropriate responding

(2016) S.A. Barnes et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology

(2016) Jo C. Neill et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The dopamine D 3 -preferring D 2 /D 3 dopamine receptor partial agonist, cariprazine, reverses behavioural changes in a rat neurodevelopmental model for schizophrenia

(2016) David J.G. Watson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Premature responses in the five-choice serial reaction time task reflect rodents’ temporal strategies: evidence from no-light and pharmacological challenges

(2016) Zackary A. Cope et al.   PSYCHOPHARMACOLOGY

Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism

(2015) Andrea de Bartolomeis et al.   CNS DRUGS

Glutamate and dopamine in schizophrenia: An update for the 21st century

(2015) Oliver Howes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Deficits in Prefrontal Cortical and Extrastriatal Dopamine Release in Schizophrenia

(2015) Mark Slifstein et al.   JAMA Psychiatry

The effects of acute and repeated administration of ketamine on attentional performance in the five-choice serial reaction time task in rats

(2014) Agnieszka Nikiforuk et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Developing treatments for cognitive deficits in schizophrenia: The challenge of translation

(2014) JW Young et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Nucleus accumbens core and shell inactivation differentially affects impulsive behaviours in rats

(2014) Malte Feja et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Serotoninergic and dopaminergic modulation of cortico-striatal circuit in executive and attention deficits induced by NMDA receptor hypofunction in the 5-choice serial reaction time task

(2014) Mirjana Carli et al.   Frontiers in Neural Circuits

Social interaction and social withdrawal in rodents as readouts for investigating the negative symptoms of schizophrenia

(2013) Christina A. Wilson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Prefrontal dopamine and behavioral flexibility: shifting from an “inverted-U” toward a family of functions

(2013) Stan B. Floresco   Frontiers in Neuroscience

Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia

(2012) C S Weickert et al.   MOLECULAR PSYCHIATRY

Cariprazine, a dopamine D3-receptor-preferring partial agonist, blocks phencyclidine-induced impairments of working memory, attention set-shifting, and recognition memory in the mouse

(2012) Ross Zimnisky et al.   PSYCHOPHARMACOLOGY

Schizophrenia: Treatment Targets Beyond Monoamine Systems

(2011) Hisham M. Ibrahim et al.   Annual Review of Pharmacology and Toxicology

Pharmacologic Rescue of Motivational Deficit in an Animal Model of the Negative Symptoms of Schizophrenia

(2011) Eleanor H. Simpson et al.   BIOLOGICAL PSYCHIATRY

Enhanced Control of Attention by Stimulating Mesolimbic-Corticopetal Cholinergic Circuitry

(2011) M. St. Peters et al.   JOURNAL OF NEUROSCIENCE

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

(2011) István Gyertyán et al.   NEUROCHEMISTRY INTERNATIONAL

D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex

(2011) Y.-C. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

D1 receptor activation improves vigilance in rats as measured by the 5-choice continuous performance test

(2011) Samuel A. Barnes et al.   PSYCHOPHARMACOLOGY

Disruption of Performance in the Five-Choice Serial Reaction Time Task Induced By Administration of N-Methyl-D-Aspartate Receptor Antagonists: Relevance to Cognitive Dysfunction in Schizophrenia

(2010) Nurith Amitai et al.   BIOLOGICAL PSYCHIATRY

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

(2010) B. Kiss et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Animal models of cognitive dysfunction and negative symptoms of schizophrenia: Focus on NMDA receptor antagonism

(2010) Joanna C. Neill et al.   PHARMACOLOGY & THERAPEUTICS

Dissociation of acute and chronic intermittent phencyclidine-induced performance deficits in the 5-choice serial reaction time task: influence of clozapine

(2010) David M. Thomson et al.   PSYCHOPHARMACOLOGY

Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex

(2010) Mirjana Carli et al.   PSYCHOPHARMACOLOGY

Modelling prefrontal cortex deficits in schizophrenia: implications for treatment

(2008) J A Pratt et al.   BRITISH JOURNAL OF PHARMACOLOGY

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

(2008) István Gyertyán et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15

(2008) Béla Kiss et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Increased impulsivity and disrupted attention induced by repeated phencyclidine are not attenuated by chronic quetiapine treatment

(2008) Nurith Amitai et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors

(2008) Taku Nagai et al.   PSYCHOPHARMACOLOGY