The Association between Early-Life Gut Microbiota and Long-Term Health and Diseases

Gut microbiome and cardiovascular disease

(2020) Yongzhong Zhao et al.   CURRENT OPINION IN CARDIOLOGY

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

(2020) Ikuo Kimura et al.   SCIENCE

The Evolving Microbiome from Pregnancy to Early Infancy: A Comprehensive Review

(2020) María Dolores Mesa et al.   Nutrients

The Role of the Microbiota–Gut–Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases

(2020) Mark Obrenovich et al.   Microorganisms

Ecological succession in the vaginal microbiota during pregnancy and birth

(2020) M. A. Rasmussen et al.   ISME Journal

The Effects of Urbanization on the Infant Gut Microbiota and Health Outcomes

(2020) Siobhan Brushett et al.   Frontiers in Pediatrics

Amyotrophic lateral sclerosis and intestinal microbiota—toward establishing cause and effect

(2020) Marc Gotkine et al.   Gut Microbes

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Parkinson’s Disease in Mouse: Potential Association between Neurotransmitter Disturbance and Gut Microbiota Dysbiosis

(2020) Yuanhui Zhu et al.   ACS Chemical Neuroscience

Factors affecting early-life intestinal microbiota development

(2020) Yvan Vandenplas et al.   NUTRITION

The relationship between epigenetics and microbiota in neuropsychiatric diseases

(2020) Madia Lozupone et al.   Epigenomics

Longitudinal Microbiome Composition and Stability Correlate with Increased Weight and Length of Very-Low-Birth-Weight Infants

(2019) Alyson L. Yee et al.   mSystems

Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

(2019) Stephen S. Dominy et al.   Science Advances

Shaping the Gut Microbiota by Breastfeeding: The Gateway to Allergy Prevention?

(2019) Lieke W. J. van den Elsen et al.   Frontiers in Pediatrics

Mechanisms linking preterm birth to onset of cardiovascular disease later in adulthood

(2019) Mahesh Bavineni et al.   EUROPEAN HEART JOURNAL

Effects of early life NICU stress on the developing gut microbiome

(2019) Amy L. D’Agata et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Birth Mode, Breastfeeding, Pet Exposure, and Antibiotic Use: Associations With the Gut Microbiome and Sensitization in Children

(2019) Haejin Kim et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Man and the Microbiome: A New Theory of Everything?

(2019) Mary I. Butler et al.   Annual Review of Clinical Psychology

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk: A Cross-Sectional Study

(2019) Alexander Kurilshikov et al.   CIRCULATION RESEARCH

Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice

(2019) Joana Torres et al.   GUT

Factors influencing the gut microbiome in children: from infancy to childhood

(2019) Shreyas V Kumbhare et al.   JOURNAL OF BIOSCIENCES

The Preterm Gut Microbiota: An Inconspicuous Challenge in Nutritional Neonatal Care

(2019) Jannie G. E. Henderickx et al.   Frontiers in Cellular and Infection Microbiology

Potential roles of gut microbiome and metabolites in modulating ALS in mice

(2019) Eran Blacher et al.   NATURE

Impact of maternal smoking on the infant gut microbiota and its association with child overweight: a scoping review

(2019) Cara McLean et al.   World Journal of Pediatrics

Microbiome evolution during host aging

(2019) Francisco Daniel Davila Aleman et al.   PLoS Pathogens

Microbiome and type 1 diabetes

(2019) Heli Siljander et al.   EBioMedicine

Temporal development of the infant gut microbiome

(2019) Rebecca E. Moore et al.   Open Biology

Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice

(2019) Claudia Figueroa-Romero et al.   Disease Models & Mechanisms

Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

(2019) Marta Reyman et al.   Nature Communications

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

(2018) Richard G. Brown et al.   BMC Medicine

Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth

(2018) Caroline C. Gillis et al.   Cell Host & Microbe

Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease: a population-based study

(2018) Anne K Örtqvist et al.   GUT

Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease

(2018) Valentina Caputi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Altered gut microbiota profile in patients with generalized anxiety disorder

(2018) Hai-yin Jiang et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Healthy hosts rule within: ecological forces shaping the gut microbiota

(2018) Mariana X. Byndloss et al.   Mucosal Immunology

The fecal microbiome of ALS patients

(2018) David Brenner et al.   NEUROBIOLOGY OF AGING

The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth

(2018) Diana A. Chernikova et al.   PEDIATRIC RESEARCH

Reduced microbiome alpha diversity in young patients with ADHD

(2018) Alexander Prehn-Kristensen et al.   PLoS One

Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

(2018) Filipe De Vadder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of the epigenome during early-life stress

(2018) S. Barnett Burns et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation

(2018) Juliana Durack et al.   Nature Communications

Changes of Colonic Bacterial Composition in Parkinson’s Disease and Other Neurodegenerative Diseases

(2018) Sara Gerhardt et al.   Nutrients

Factors Affecting Gastrointestinal Microbiome Development in Neonates

(2018) Clara Chong et al.   Nutrients

Intestinal microbiota development and gestational age in preterm neonates

(2018) Katri Korpela et al.   Scientific Reports

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

(2018) Bruno Bonaz et al.   Frontiers in Neuroscience

Disruption of maternal gut microbiota during gestation alters offspring microbiota and immunity

(2018) Donald D. Nyangahu et al.   Microbiome

Early differences in fecal microbiota composition in children may predict overweight

(2018) Marko Kalliomäki et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn’s Disease in Children

(2018) Livia Lindoso et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The association between antibiotic use in infancy and childhood overweight or obesity: a systematic review and meta-analysis

(2018) S. A. Miller et al.   Obesity Reviews

SCFAs strongly stimulate PYY production in human enteroendocrine cells

(2018) P. Larraufie et al.   Scientific Reports

Childhood adversity impact on gut microbiota and inflammatory response to stress during pregnancy

(2018) Liisa Hantsoo et al.   BRAIN BEHAVIOR AND IMMUNITY

The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications

(2018) Vadim Osadchiy et al.   Clinical Gastroenterology and Hepatology

The vermiform appendix impacts the risk of developing Parkinson’s disease

(2018) Bryan A. Killinger et al.   Science Translational Medicine

Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential

(2018) Linda Wampach et al.   Nature Communications

Obesity: A New Adverse Effect of Antibiotics?

(2018) Fernando S. Del Fiol et al.   Frontiers in Pharmacology

Developmental Tuning of Epigenetic Clock

(2018) Alexander Vaiserman   Frontiers in Genetics

Factors Influencing the Gut Microbiota, Inflammation, and Type 2 Diabetes

(2017) Li Wen et al.   JOURNAL OF NUTRITION

The gut microbiome composition associates with bipolar disorder and illness severity

(2017) Simon J. Evans et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

(2017) Erin M. Hill-Burns et al.   MOVEMENT DISORDERS

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

The vaginal microbiome of pregnant women is less rich and diverse, with lower prevalence of Mollicutes, compared to non-pregnant women

(2017) Aline C. Freitas et al.   Scientific Reports

Colonization and Succession within the Human Gut Microbiome by Archaea, Bacteria, and Microeukaryotes during the First Year of Life

(2017) Linda Wampach et al.   Frontiers in Microbiology

Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor 109A Signaling

(2017) Maria M. M. Kaisar et al.   Frontiers in Immunology

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Epigenetic Matters: The Link between Early Nutrition, Microbiome, and Long-term Health Development

(2017) Flavia Indrio et al.   Frontiers in Pediatrics

Analysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response

(2017) Emanuel Schwarz et al.   SCHIZOPHRENIA RESEARCH

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

(2017) T. Harach et al.   Scientific Reports

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma

(2016) L. T. Stiemsma et al.   CLINICAL SCIENCE

The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System

(2016) Yuuki Obata et al.   GASTROENTEROLOGY

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

(2016) Floris Imhann et al.   GUT

Maternal Antibiotic Treatment Impacts Development of the Neonatal Intestinal Microbiome and Antiviral Immunity

(2016) Gabriela Gonzalez-Perez et al.   JOURNAL OF IMMUNOLOGY

Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice

(2016) Joseph D. Planer et al.   NATURE

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

The microbiome in early life: implications for health outcomes

(2016) Sabrina Tamburini et al.   NATURE MEDICINE

The role of the intestinal microbiota in type 1 diabetes mellitus

(2016) Mikael Knip et al.   Nature Reviews Endocrinology

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

(2016) Marcus M. Unger et al.   PARKINSONISM & RELATED DISORDERS

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders

(2016) Ji Yoo et al.   Nutrients

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances

(2016) M. P. Francino   Frontiers in Microbiology

Evaluation of the Microbial Diversity in Amyotrophic Lateral Sclerosis Using High-Throughput Sequencing

(2016) Xin Fang et al.   Frontiers in Microbiology

Microbiota in Breast Milk of Chinese Lactating Mothers

(2016) Olga Sakwinska et al.   PLoS One

Bacterial Communities Associated with Atherosclerotic Plaques from Russian Individuals with Atherosclerosis

(2016) Elvira E. Ziganshina et al.   PLoS One

Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid

(2016) Maria Carmen Collado et al.   Scientific Reports

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Gut microbiome and innate immune response patterns in IgE-associated eczema

(2015) C. E. West et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Antibiotics and the developing infant gut microbiota and resistome

(2015) Molly K Gibson et al.   CURRENT OPINION IN MICROBIOLOGY

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Spreading of pathology in neurodegenerative diseases: a focus on human studies

(2015) Johannes Brettschneider et al.   NATURE REVIEWS NEUROSCIENCE

Gut microbiota and aging

(2015) P. W. OToole et al.   SCIENCE

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Structure and function of the healthy pre-adolescent pediatric gut microbiome

(2015) Emily B. Hollister et al.   Microbiome

Intestinal Dysbiosis and Lowered Serum Lipopolysaccharide-Binding Protein in Parkinson’s Disease

(2015) Satoru Hasegawa et al.   PLoS One

The vaginal microbiome during pregnancy and the postpartum period in a European population

(2015) David A. MacIntyre et al.   Scientific Reports

The epigenetic side of human adaptation: hypotheses, evidences and theories

(2014) Cristina Giuliani et al.   ANNALS OF HUMAN BIOLOGY

Assessing the Public Health Impact of Developmental Origins of Health and Disease (DOHaD) Nutrition Interventions

(2014) Maria Luisa Garmendia et al.   ANNALS OF NUTRITION AND METABOLISM

Altered Fecal Microbiota Composition Associated with Food Allergy in Infants

(2014) Zongxin Ling et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Standard of hygiene and immune adaptation in newborn infants

(2014) Henna Kallionpää et al.   CLINICAL IMMUNOLOGY

Heterogeneity and phenotypic plasticity of glial cells in the mammalian enteric nervous system

(2014) Werend Boesmans et al.   GLIA

The intestinal microbiota composition and weight development in children: the KOALA Birth Cohort Study

(2014) L E J M Scheepers et al.   INTERNATIONAL JOURNAL OF OBESITY

Deletion of Serum Amyloid A3 Improves High Fat High Sucrose Diet-Induced Adipose Tissue Inflammation and Hyperlipidemia in Female Mice

(2014) Laura J. den Hartigh et al.   PLoS One

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic Treatment of Pregnant Non-Obese Diabetic Mice Leads to Altered Gut Microbiota and Intestinal Immunological Changes in the Offspring

(2014) N. Tormo-Badia et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The role of extracellular Tau in the spreading of neurofibrillary pathology

(2014) Miguel Medina et al.   Frontiers in Cellular Neuroscience

High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model

(2014) Jun Ma et al.   Nature Communications

Manipulation of the Intestinal Microbiome in Newborn Infants

(2014) Nicole Cacho et al.   Advances in Nutrition

Pathogenic microbes, the microbiome, and Alzheimer’s disease (AD)

(2014)   Frontiers in Aging Neuroscience

Diet and the development of the human intestinal microbiome

(2014) Noah Voreades et al.   Frontiers in Microbiology

Development of the preterm infant gut microbiome: a research priority

(2014) Maureen W Groer et al.   Microbiome

Microbes in the neonatal intensive care unit resemble those found in the gut of premature infants

(2014) Brandon Brooks et al.   Microbiome

The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women

(2014) Roberto Romero et al.   Microbiome

Early-Life Stress, HPA Axis Adaptation, and Mechanisms Contributing to Later Health Outcomes

(2014) Jayanthi Maniam et al.   Frontiers in Endocrinology

External Influence of Early Childhood Establishment of Gut Microbiota and Subsequent Health Implications

(2014) Peris Mumbi Munyaka et al.   Frontiers in Pediatrics

More than just a gut instinct–the potential interplay between a baby's nutrition, its gut microbiome, and the epigenome

(2013) Mona Mischke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The individual-specific and diverse nature of the preterm infant microbiota

(2013) Eoin Barrett et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Inflammation and immune system interactions in atherosclerosis

(2013) Bart Legein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antibiotic treatment during infancy and increased body mass index in boys: an international cross-sectional study

(2013) R Murphy et al.   INTERNATIONAL JOURNAL OF OBESITY

Surface Microbes in the Neonatal Intensive Care Unit: Changes with Routine Cleaning and over Time

(2013) N. A. Bokulich et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Preterm Birth and Neurodevelopment: A Review of Outcomes and Recommendations for Early Identification and Cost-effective Interventions

(2013) P. S. Sutton et al.   JOURNAL OF TROPICAL PEDIATRICS

Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy

(2013) Romy Gaillard et al.   Obesity

Bacterial Diversity in Two Neonatal Intensive Care Units (NICUs)

(2013) Krissi M. Hewitt et al.   PLoS One

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota

(2013) Deirdre E. O’Hanlon et al.   PLoS One

Development of intestinal microbiota in infants and its impact on health

(2013) Sebastien Matamoros et al.   TRENDS IN MICROBIOLOGY

The role of gut microbiota in programming the immune phenotype

(2013) M. Weng et al.   Journal of Developmental Origins of Health and Disease

Novel Developmental Analyses Identify Longitudinal Patterns of Early Gut Microbiota that Affect Infant Growth

(2013) Richard A. White et al.   PLoS Computational Biology

Infant antibiotic exposures and early-life body mass

(2012) L Trasande et al.   INTERNATIONAL JOURNAL OF OBESITY

Is maternal diabetes a risk factor for childhood obesity?

(2012) Shobha H. Mehta et al.   Journal of Maternal-Fetal & Neonatal Medicine

100 years of Lewy pathology

(2012) Michel Goedert et al.   Nature Reviews Neurology

Effect of Breast and Formula Feeding on Gut Microbiota Shaping in Newborns

(2012) Federica Guaraldi et al.   Frontiers in Cellular and Infection Microbiology

Microbiota profile in feces of breast- and formula-fed newborns by using fluorescence in situ hybridization (FISH)

(2011) Eugenia Bezirtzoglou et al.   ANAEROBE

Obesity and the gut microbiota: does up-regulating colonic fermentation protect against obesity and metabolic disease?

(2011) Lorenza Conterno et al.   Genes and Nutrition

Determinants of the human infant intestinal microbiota after the introduction of first complementary foods in infant samples from five European centres

(2011) M. Fallani et al.   MICROBIOLOGY-SGM

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Unravelling the effects of the environment and host genotype on the gut microbiome

(2011) Aymé Spor et al.   NATURE REVIEWS MICROBIOLOGY

The Role of Microbes in Developmental Immunologic Programming

(2011) Jess L Kaplan et al.   PEDIATRIC RESEARCH

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Effect of mother’s weight on infant’s microbiota acquisition, composition, and activity during early infancy: a prospective follow-up study initiated in early pregnancy

(2010) Maria Carmen Collado et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet

(2010) Mikael Bjursell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Programming infant gut microbiota: influence of dietary and environmental factors

(2010) Tatiana Milena Marques et al.   CURRENT OPINION IN BIOTECHNOLOGY

Poor maternal nutrition leads to alterations in oxidative stress, antioxidant defense capacity, and markers of fibrosis in rat islets: potential underlying mechanisms for development of the diabetic phenotype in later life

(2010) Jane L. Tarry-Adkins et al.   FASEB JOURNAL

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic Use in Children Is Associated With Increased Risk of Asthma

(2009) F. Marra et al.   PEDIATRICS

Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies

(2008) C. R. Cardwell et al.   DIABETOLOGIA

HelicobacterHypothesis for Idiopathic Parkinsonism: Before and Beyond

(2008) R. John Dobbs et al.   HELICOBACTER

Perinatal and Neonatal Manipulation of the Intestinal Microbiome: A Note of Caution

(2008) Josef Neu   NUTRITION REVIEWS

Microbial Prevalence, Diversity and Abundance in Amniotic Fluid During Preterm Labor: A Molecular and Culture-Based Investigation

(2008) Daniel B. DiGiulio et al.   PLoS One

Is meconium from healthy newborns actually sterile?

(2008) Esther Jiménez et al.   RESEARCH IN MICROBIOLOGY

Early life programming of obesity and metabolic disease

(2007) E.C. Cottrell et al.   PHYSIOLOGY & BEHAVIOR