The Role of the Microbiota–Gut–Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases

The Microbiota–Gut–Brain Axis Heart Shunt Part I: The French Paradox, Heart Disease and the Microbiota

(2020) Mark Obrenovich et al.   Microorganisms

The Microbiota–Gut–Brain Axis–Heart Shunt Part II: Prosaic Foods and the Brain–Heart Connection in Alzheimer Disease

(2020) Mark Obrenovich et al.   Microorganisms

Repurposing of the β-Lactam Antibiotic, Ceftriaxone for Neurological Disorders: A Review

(2019) Ebrahim M. Yimer et al.   Frontiers in Neuroscience

Antibiotics Use and Risk of Amyotrophic Lateral Sclerosis in Sweden

(2019) Jiangwei Sun et al.   EUROPEAN JOURNAL OF NEUROLOGY

Modification of the gut microbiome to combat neurodegeneration

(2019) Andrew Octavian Sasmita   REVIEWS IN THE NEUROSCIENCES

Functional microglia neurotransmitters in amyotrophic lateral sclerosis

(2019) Cinzia Volonté et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Extracellular RNAs as Biomarkers of Sporadic Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases

(2019) Takashi Hosaka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Potential roles of gut microbiome and metabolites in modulating ALS in mice

(2019) Eran Blacher et al.   NATURE

ALS/SURV: a modification of the CAFS statistic

(2019) Stephen A. Goutman et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Systematic Evaluation of CRISPRa and CRISPRi Modalities Enables Development of a Multiplexed, Orthogonal Gene Activation and Repression System

(2019) Andrea Martella et al.   ACS Synthetic Biology

Potential Role of the Gut Microbiome in ALS: A Systematic Review

(2018) Michelle L. Wright et al.   Biological Research for Nursing

Faecalibacterium prausnitzii and a Prebiotic Protect Intestinal Health in a Mouse Model of Antibiotic and Clostridium difficile Exposure

(2018) Sanjoy Roychowdhury et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

(2018) Krista J. Spiller et al.   NATURE NEUROSCIENCE

Microbiome, Immunomodulation, and the Neuronal System

(2018) Eric Marietta et al.   Neurotherapeutics

Active Invasion of Porphyromonas gingivalis and Infection-Induced Complement Activation in ApoE-/- Mice Brains

(2018) Sophie Poole et al.   JOURNAL OF ALZHEIMERS DISEASE

Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs

(2018) Manoj Kumar Jaiswal   MEDICINAL RESEARCH REVIEWS

Vitamin D protects against hippocampal apoptosis related with seizures induced by kainic acid and pentylenetetrazol in rats

(2018) Sevim Şahin et al.   EPILEPSY RESEARCH

Coffee, tea, and caffeine intake and amyotrophic lateral sclerosis mortality in a pooled analysis of eight prospective cohort studies

(2018) J. Petimar et al.   EUROPEAN JOURNAL OF NEUROLOGY

Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology

(2018) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

The Emerging Role of Microbial Biofilm in Lyme Neuroborreliosis

(2018) Enea Gino Di Domenico et al.   Frontiers in Neurology

Vitamin D in amyotrophic lateral sclerosis

(2017) Laura Libonati   FUNCTIONAL NEUROLOGY

Towards a Better Understanding of GABAergic Remodeling in Alzheimer’s Disease

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Valery L Feigin et al.   LANCET NEUROLOGY

Lynn Margulis and the endosymbiont hypothesis: 50 years later

(2017) Michael W. Gray   MOLECULAR BIOLOGY OF THE CELL

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

A journey into the brain: insight into how bacterial pathogens cross blood–brain barriers

(2017) Mathieu Coureuil et al.   NATURE REVIEWS MICROBIOLOGY

Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury

(2017) Yinghui Zhong et al.   Neural Regeneration Research

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease

(2017) Amit U. Joshi et al.   Oncotarget

The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches

(2017) Maria Concetta Geloso et al.   Frontiers in Aging Neuroscience

Ciprofloxacin triggered glutamate production by Corynebacterium glutamicum

(2016) Dorit Lubitz et al.   BMC MICROBIOLOGY

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

Current Therapy of Drugs in Amyotrophic Lateral Sclerosis

(2016) Haiyan Lu et al.   Current Neuropharmacology

Formation of propionate and butyrate by the human colonic microbiota

(2016) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis

(2016) Tesfaye W. Tefera et al.   PLoS One

Correction: Importance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In Vivo

(2016) Brintha Parasumanna Girinathan et al.   PLoS One

Response to Comment on "A small-molecule antivirulence agent for treating Clostridium difficile infection"

(2016) K. O. Bender et al.   Science Translational Medicine

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

Human gut microbiota: the links with dementia development

(2016) Rashad Alkasir et al.   Protein & Cell

Genotype-phenotype correlations of amyotrophic lateral sclerosis

(2016) Hong-Fu Li et al.   Translational Neurodegeneration

Potential role of antimicrobial peptides in the early onset of Alzheimer's disease

(2015) Mick M. Welling et al.   Alzheimers & Dementia

Potential role of gut microbiota and tissue barriers in Parkinson's disease and amyotrophic lateral sclerosis

(2015) Xin Fang   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

(2015) Silvana Konermann et al.   NATURE

Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease

(2015) Joannee Zumkehr et al.   NEUROBIOLOGY OF AGING

Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis

(2015) Giuseppe Battaglia et al.   NEUROBIOLOGY OF DISEASE

Treatment with Hydrogen-Rich Saline Delays Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis

(2015) Yu Zhang et al.   NEUROCHEMICAL RESEARCH

Microgliosis in the Injured Brain

(2015) Ting Li et al.   NEUROSCIENTIST

Quantification of Anthocyanins in Elderberry and Chokeberry Dietary Supplements

(2015) Christian Vlachojannis et al.   PHYTOTHERAPY RESEARCH

Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody

(2015) Kazuhiro Kurosawa et al.   Acta Neuropathologica Communications

Potential Therapeutic Drugs and Methods for the Treatment of Amyotrophic Lateral Sclerosis

(2014) G. Yacila et al.   CURRENT MEDICINAL CHEMISTRY

Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites

(2014) N. Simon-Delso et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Ceftriaxone pretreatment protects rats against cerebral ischemic injury by attenuating microglial activation-induced IL-1β expression

(2014) Yang Lujia et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial

(2014) Merit E Cudkowicz et al.   LANCET NEUROLOGY

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

(2014) David Bikard et al.   NATURE BIOTECHNOLOGY

7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis

(2014) Orhan Tansel Korkmaz et al.   NEUROSCIENCE LETTERS

Astrocytic Dysfunction and Addiction

(2014) Michael D. Scofield et al.   NEUROSCIENTIST

Early-Stage Treatment with Withaferin A Reduces Levels of Misfolded Superoxide Dismutase 1 and Extends Lifespan in a Mouse Model of Amyotrophic Lateral Sclerosis

(2014) Priyanka Patel et al.   Neurotherapeutics

Correction: A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis

(2014) Nico Melzer et al.   PLoS One

A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model

(2014) Kazunori Tanaka et al.   PLoS One

Pathogenic microbes, the microbiome, and Alzheimer’s disease (AD)

(2014)   Frontiers in Aging Neuroscience

Vitamin D3 at 50x AI Attenuates the Decline in Paw Grip Endurance, but Not Disease Outcomes, in the G93A Mouse Model of ALS, and Is Toxic in Females

(2013) Alexandro Gianforcaro et al.   PLoS One

γ-Aminobutyric acid production by culturable bacteria from the human intestine

(2012) E. Barrett et al.   JOURNAL OF APPLIED MICROBIOLOGY

Inflammation and neurovascular changes in amyotrophic lateral sclerosis

(2012) M.C. Evans et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Excitotoxic potential of the cyanotoxin β-methyl-amino-l-alanine (BMAA) in primary human neurons

(2012) Alexander S. Chiu et al.   TOXICON

Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites

(2011) N Brouwers et al.   MOLECULAR PSYCHIATRY

Astrogliosis in CNS Pathologies: Is There A Role for Microglia?

(2010) Dan Zhang et al.   MOLECULAR NEUROBIOLOGY

White Matter Lesions Suggestive of Amyotrophic Lateral Sclerosis Attributed to Celiac Disease

(2009) K.J. Brown et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

BMAA – an unusual cyanobacterial neurotoxin

(2009) Kaivalya J. Vyas et al.   Amyotrophic Lateral Sclerosis

A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis

(2009) Robert M. Pascuzzi et al.   Amyotrophic Lateral Sclerosis

Prognostic factors in ALS: A critical review

(2009) Adriano Chiò et al.   Amyotrophic Lateral Sclerosis

A high γ-aminobutyric acid-producingLactobacillus brevis isolated from Chinese traditionalpaocai

(2009) Haixing Li et al.   ANNALS OF MICROBIOLOGY

Improved heterologous gene expression in Trichoderma reesei by cellobiohydrolase I gene (cbh1) promoter optimization

(2008) Ti Liu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

(2008) Gjumrakch Aliev et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke

(2008) Christa Thöne-Reineke et al.   JOURNAL OF HYPERTENSION

Antioxidant Therapy in Alzheimers Disease: Theory and Practice

(2008) Gjumrakch Aliev et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Homeostasis of glutamate in brain fluids: An accelerated brain-to-blood efflux of excess glutamate is produced by blood glutamate scavenging and offers protection from neuropathologies

(2008) V.I. Teichberg et al.   NEUROSCIENCE

Metabolic regulation and overproduction of primary metabolites

(2008) Sergio Sanchez et al.   Microbial Biotechnology