Trichostatin A ameliorates Alzheimer’s disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Trichostatin A ameliorates Alzheimer’s disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice
Authors
Keywords
-
Journal
Alzheimers Research & Therapy
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-05
DOI
10.1186/s13195-020-00746-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Abnormal Serum Bilirubin/Albumin Concentrations in Dementia Patients With Aβ Deposition and the Benefit of Intravenous Albumin Infusion for Alzheimer’s Disease Treatment
- (2020) Xiaomei Zhong et al. Frontiers in Neuroscience
- Targeting amyloid clearance in Alzheimer's disease as a therapeutic strategy
- (2019) Natalia N. Nalivaeva et al. BRITISH JOURNAL OF PHARMACOLOGY
- LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer’s Disease
- (2019) Bart Van Gool et al. MOLECULAR NEUROBIOLOGY
- Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics
- (2019) Alan Talevi et al. Expert Opinion on Drug Discovery
- TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
- (2018) Yingjun Zhao et al. NEURON
- Clearance of Amyloid Beta and Tau in Alzheimer’s Disease: from Mechanisms to Therapy
- (2018) Shu-Hui Xin et al. NEUROTOXICITY RESEARCH
- Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH
- (2018) Hari Prasad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The anti-tumor effects of dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A on inducing autophagy in esophageal squamous cell carcinoma
- (2018) Ning Wu et al. Journal of Cancer
- Tubastatin A/ACY-1215 Improves Cognition in Alzheimer's Disease Transgenic Mice
- (2018) Ling Zhang et al. JOURNAL OF ALZHEIMERS DISEASE
- Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model
- (2018) Karolina J. Janczura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial
- (2017) Mercè Boada et al. JOURNAL OF ALZHEIMERS DISEASE
- Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region
- (2017) Tae Su Choi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony
- (2017) Stefania Forner et al. TRENDS IN NEUROSCIENCES
- Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease
- (2017) Yitshak I. Francis et al. JOURNAL OF ALZHEIMERS DISEASE
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways
- (2015) Jianbin Zhang et al. Autophagy
- Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
- (2015) Steffen E. Storck et al. JOURNAL OF CLINICAL INVESTIGATION
- Alginate-Derived Oligosaccharide Inhibits Neuroinflammation and Promotes Microglial Phagocytosis of β-Amyloid
- (2015) Rui Zhou et al. Marine Drugs
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue
- (2015) Gavin Rumbaugh et al. NEUROPSYCHOPHARMACOLOGY
- Effect of Trichostatin A on Gelsolin Levels, Proteolysis of Amyloid Precursor Protein, and Amyloid Beta-Protein Load in the Brain of Transgenic Mouse Model of Alzheimer's Disease
- (2014) Wenzhong Yang et al. Current Alzheimer Research
- Trichostatin A increases the levels of plasma gelsolin and amyloid beta-protein in a transgenic mouse model of Alzheimer's disease
- (2014) Wenzhong Yang et al. LIFE SCIENCES
- Clearance of Amyloid-Beta in Alzheimer’s Disease: Shifting the Action Site from Center to Periphery
- (2014) Yu-Hui Liu et al. MOLECULAR NEUROBIOLOGY
- The histone deacetylase inhibitor trichostatin A induces neurite outgrowth in PC12 cells via the epigenetically regulated expression of the nur77 gene
- (2014) Takuma Tomioka et al. NEUROSCIENCE RESEARCH
- Epigenetic suppression of hippocampal BDNF mediates the memory deficiency induced by amyloid fibrils
- (2014) Bei-Yun Wang et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Neuronal Clearance of Amyloid- by Endocytic Receptor LRP1
- (2013) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Object recognition test in mice
- (2013) Marianne Leger et al. Nature Protocols
- Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
- (2013) Kurt M. Lucin et al. NEURON
- Ubiquitin B in Cervical Cancer: Critical for the Maintenance of Cancer Stem-Like Cell Characters
- (2013) Yuan Tian et al. PLoS One
- Review: Microglia of the aged brain: primed to be activated and resistant to regulation
- (2012) D. M. Norden et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Peripheral reduction of β-amyloid is sufficient to reduce brain β-amyloid: Implications for Alzheimer's disease
- (2011) J. Gregor Sutcliffe et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Sink Hypothesis and Therapeutic Strategies for Attenuating Aβ Levels
- (2011) Yan Zhang et al. NEUROSCIENTIST
- Microglia Mediate the Clearance of Soluble A through Fluid Phase Macropinocytosis
- (2009) S. Mandrekar et al. JOURNAL OF NEUROSCIENCE
- Human Microglial Cells Synthesize Albumin in Brain
- (2008) Sung-Min Ahn et al. PLoS One
- Aβ inhibits the proteasome and enhances amyloid and tau accumulation
- (2007) Bertrand P. Tseng et al. NEUROBIOLOGY OF AGING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More