Review: Microglia of the aged brain: primed to be activated and resistant to regulation
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Title
Review: Microglia of the aged brain: primed to be activated and resistant to regulation
Authors
Keywords
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Journal
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Volume 39, Issue 1, Pages 19-34
Publisher
Wiley
Online
2012-10-06
DOI
10.1111/j.1365-2990.2012.01306.x
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Note: Only part of the references are listed.- Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX3CR1)-deficient mice
- (2012) Angela W. Corona et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglia Modulate Hippocampal Neural Precursor Activity in Response to Exercise and Aging
- (2012) J. Vukovic et al. JOURNAL OF NEUROSCIENCE
- Age-related changes in the hippocampus (loss of synaptophysin and glial–synaptic interaction) are modified by systemic treatment with an NCAM-derived peptide, FGL
- (2011) Bunmi Ojo et al. BRAIN BEHAVIOR AND IMMUNITY
- Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice
- (2011) Ashley M. Fenn et al. BRAIN BEHAVIOR AND IMMUNITY
- CD200 fusion protein decreases microglial activation in the hippocampus of aged rats
- (2011) F. Fionnuala Cox et al. BRAIN BEHAVIOR AND IMMUNITY
- Wheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged mice
- (2011) Rachel A. Kohman et al. BRAIN BEHAVIOR AND IMMUNITY
- Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning
- (2011) Michael D. Burton et al. BRAIN BEHAVIOR AND IMMUNITY
- Cognitive and Behavioral Consequences of Impaired Immunoregulation in Aging
- (2011) Angela W. Corona et al. Journal of Neuroimmune Pharmacology
- Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide
- (2011) Angela W Corona et al. Journal of Neuroinflammation
- Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment
- (2011) Heather D VanGuilder et al. Journal of Neuroinflammation
- Little Exercise, Big Effects: Reversing Aging and Infection-Induced Memory Deficits, and Underlying Processes
- (2011) R. M. Barrientos et al. JOURNAL OF NEUROSCIENCE
- Aging and a Peripheral Immune Challenge Interact to Reduce Mature Brain-Derived Neurotrophic Factor and Activation of TrkB, PLC 1, and ERK in Hippocampal Synaptoneurosomes
- (2011) G. P. Cortese et al. JOURNAL OF NEUROSCIENCE
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation
- (2011) Amar Sahay et al. NATURE
- Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus
- (2011) Timothy R. Chapman et al. NEUROBIOLOGY OF AGING
- Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior
- (2011) Ebrahim Haroon et al. NEUROPSYCHOPHARMACOLOGY
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
- Age-related alterations in the dynamic behavior of microglia
- (2010) Mausam R. Damani et al. AGING CELL
- CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models
- (2010) Sungho Lee et al. AMERICAN JOURNAL OF PATHOLOGY
- Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge
- (2010) Angela M. Wynne et al. BRAIN BEHAVIOR AND IMMUNITY
- Alternatively activated myeloid (M2) cells enhance cognitive function in immune compromised mice
- (2010) Noel C. Derecki et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis
- (2010) Amanda Sierra et al. Cell Stem Cell
- Dysregulated neuronal–microglial cross-talk during aging, stress and inflammation
- (2010) Heidi A. Jurgens et al. EXPERIMENTAL NEUROLOGY
- TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke
- (2010) Kristian P Doyle et al. Journal of Neuroinflammation
- Synaptic Correlates of Increased Cognitive Vulnerability with Aging: Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1
- (2010) T. R. Chapman et al. JOURNAL OF NEUROSCIENCE
- Luteolin Inhibits Microglia and Alters Hippocampal-Dependent Spatial Working Memory in Aged Mice
- (2010) Saebyeol Jang et al. JOURNAL OF NUTRITION
- Rosiglitazone attenuates the age-related changes in astrocytosis and the deficit in LTP
- (2010) Thelma R. Cowley et al. NEUROBIOLOGY OF AGING
- Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
- (2010) eMalick G. Njie et al. NEUROBIOLOGY OF AGING
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Microglial Interactions with Synapses Are Modulated by Visual Experience
- (2010) Marie-Ève Tremblay et al. PLOS BIOLOGY
- Microglial Physiology: Unique Stimuli, Specialized Responses
- (2009) Richard M. Ransohoff et al. Annual Review of Immunology
- Characterization of the sickness response in young and aging rats following E. coli infection
- (2009) Ruth M. Barrientos et al. BRAIN BEHAVIOR AND IMMUNITY
- Central inhibition of interleukin-1β ameliorates sickness behavior in aged mice
- (2009) Jayne Abraham et al. BRAIN BEHAVIOR AND IMMUNITY
- IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344×BN F1 rats
- (2009) Matthew G. Frank et al. BRAIN BEHAVIOR AND IMMUNITY
- Age and Neuroinflammation: A Lifetime of Psychoneuroimmune Consequences
- (2009) Jonathan P. Godbout et al. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
- Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior
- (2009) J. C. O'Connor et al. JOURNAL OF IMMUNOLOGY
- Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activationin vivoandin vitro
- (2009) Anthony Lyons et al. JOURNAL OF NEUROCHEMISTRY
- Life and Death of Microglia
- (2009) Wolfgang J. Streit et al. Journal of Neuroimmune Pharmacology
- Systemic lipopolysaccharide (LPS)-induced microglial activation results in different temporal reduction of CD200 and CD200 receptor gene expression in the brain
- (2009) Willias Masocha JOURNAL OF NEUROIMMUNOLOGY
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- (2009) H. Wake et al. JOURNAL OF NEUROSCIENCE
- Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
- (2009) K. A. Kigerl et al. JOURNAL OF NEUROSCIENCE
- Blood-brain barrier alterations in ageing and dementia
- (2009) Bogdan O. Popescu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats
- (2009) Adam D. Bachstetter et al. NEUROBIOLOGY OF AGING
- Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
- (2009) Kurt M. Lucin et al. NEURON
- Consuming a Diet Supplemented with Resveratrol Reduced Infection-Related Neuroinflammation and Deficits in Working Memory in Aged Mice
- (2009) Jayne Abraham et al. REJUVENATION RESEARCH
- Exercise Increases Neural Stem Cell Number in a Growth Hormone-Dependent Manner, Augmenting the Regenerative Response in Aged Mice
- (2009) Daniel G. Blackmore et al. STEM CELLS
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- (2008) Christopher J. Henry et al. BRAIN BEHAVIOR AND IMMUNITY
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- (2008) Ruth M. Barrientos et al. BRAIN BEHAVIOR AND IMMUNITY
- Dual modulation of synaptic transmission in the nucleus tractus solitarius by prostaglandin E2 synthesized downstream of IL-1
- (2008) Vincent Marty et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Neuroinflammation and cognitive function in aged mice following minor surgery
- (2008) H.A. Rosczyk et al. EXPERIMENTAL GERONTOLOGY
- Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
- (2008) Christopher J Henry et al. Journal of Neuroinflammation
- Reverse of Age-Dependent Memory Impairment and Mitochondrial DNA Damage in Microglia by an Overexpression of Human Mitochondrial Transcription Factor A in Mice
- (2008) Y. Hayashi et al. JOURNAL OF NEUROSCIENCE
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
- Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
- (2008) J C O'Connor et al. MOLECULAR PSYCHIATRY
- A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL
- (2008) Eric J. Downer et al. NEUROBIOLOGY OF AGING
- Early age-related changes in adult hippocampal neurogenesis in C57 mice
- (2008) Nada M.-B. Ben Abdallah et al. NEUROBIOLOGY OF AGING
- Comparison of Ionized Calcium-binding Adapter Molecule 1 Immunoreactivity of the Hippocampal Dentate Gyrus and CA1 Region in Adult and Aged Dogs
- (2008) In Koo Hwang et al. NEUROCHEMICAL RESEARCH
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- Cognitive and neuroinflammatory consequences of mild repeated stress are exacerbated in aged mice
- (2008) J.B. Buchanan et al. PSYCHONEUROENDOCRINOLOGY
- Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation
- (2008) Amy F. Richwine et al. PSYCHONEUROENDOCRINOLOGY
- Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
- (2007) Jing Chen et al. BRAIN BEHAVIOR AND IMMUNITY
- From inflammation to sickness and depression: when the immune system subjugates the brain
- (2007) Robert Dantzer et al. NATURE REVIEWS NEUROSCIENCE
- Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide
- (2007) Y. Huang et al. NEUROBIOLOGY OF AGING
- Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain
- (2007) David J. Loane et al. NEUROBIOLOGY OF AGING
- Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120
- (2006) J. Abraham et al. NEUROBIOLOGY OF AGING
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