CRISPR-Mediated Engineering across the Central Dogma in Plant Biology for Basic Research and Crop Improvement

Genetic Engineering and Editing of Plants: An Analysis of New and Persisting Questions

(2020) Rebecca Mackelprang et al.   Annual Review of Plant Biology

Loss of salt tolerance during tomato domestication conferred by variation in a Na + /K + transporter

(2020) Zhen Wang et al.   EMBO JOURNAL

Construction and Analysis of GmFAD2-1A and GmFAD2-2A Soybean Fatty Acid Desaturase Mutants Based on CRISPR/Cas9 Technology

(2020) Nan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Base-Editing-Mediated Artificial Evolution of OsALS1 In Planta to Develop Novel Herbicide-Tolerant Rice Germplasms

(2020) Yongjie Kuang et al.   Molecular Plant

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

(2020) Marco Jost et al.   NATURE BIOTECHNOLOGY

Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors

(2020) Chao Li et al.   NATURE BIOTECHNOLOGY

Manipulating gene translation in plants by CRISPR–Cas9-mediated genome editing of upstream open reading frames

(2020) Xiaomin Si et al.   Nature Protocols

The R-loop Atlas of Arabidopsis Development and Responses to Environmental Stimuli

(2020) Wei Xu et al.   PLANT CELL

High-Throughput CRISPR/Cas9 Mutagenesis Streamlines Trait Gene Identification in Maize

(2020) Haijun Liu et al.   PLANT CELL

Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice

(2020) Kun Wu et al.   SCIENCE

Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9

(2020) Oliver Xiaoou Dong et al.   Nature Communications

Epigenetic Footprints of CRISPR/Cas9-Mediated Genome Editing in Plants

(2020) Jun Hyung Lee et al.   Frontiers in Plant Science

Cas9/gRNA-mediated genome editing of yeast mitochondria and Chlamydomonas chloroplasts

(2020) Byung-Chun Yoo et al.   PeerJ

m6A mRNA Modification as a New Layer of Gene Regulation in Plants

(2020) Jiwoo Kim et al.   JOURNAL OF PLANT BIOLOGY

CRISPR/Cas9 directed editing of lycopene epsilon-cyclase modulates metabolic flux for β-carotene biosynthesis in banana fruit

(2020) Navneet Kaur et al.   METABOLIC ENGINEERING

Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform

(2020) Thomas Gonatopoulos-Pournatzis et al.   NATURE BIOTECHNOLOGY

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

(2020) Xiaohui Zhang et al.   NATURE BIOTECHNOLOGY

A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing

(2020) Julian Grünewald et al.   NATURE BIOTECHNOLOGY

Highly efficient homology‐directed repair using CRISPR/Cpf1‐geminiviral replicon in tomato

(2020) Tien Van Vu et al.   PLANT BIOTECHNOLOGY JOURNAL

Modulation of shoot phosphate level and growth by PHOSPHATE1 upstream open reading frame

(2020) Rodrigo S Reis et al.   PLANT PHYSIOLOGY

m6A Editing: New Tool to Improve Crop Quality?

(2020) Hong-xiang Zheng et al.   TRENDS IN PLANT SCIENCE

The proportion of soil-borne pathogens increases with warming at the global scale

(2020) Manuel Delgado-Baquerizo et al.   Nature Climate Change

In-Frame and Frame-Shift Editing of the Ehd1 Gene to Develop Japonica Rice With Prolonged Basic Vegetative Growth Periods

(2020) Mingji Wu et al.   Frontiers in Plant Science

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing

(2020) Beverly Y. Mok et al.   NATURE

Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC–Cas9

(2020) Shengxing Wang et al.   NATURE BIOTECHNOLOGY

The Tomato Guanylate-Binding Protein SlGBP1 Enables Fruit Tissue Differentiation by Maintaining Endopolyploid Cells in a Non-proliferative State

(2020) Constance Musseau et al.   PLANT CELL

Very fast CRISPR on demand

(2020) Yang Liu et al.   SCIENCE

CRISPR artificial splicing factors

(2020) Menghan Du et al.   Nature Communications

CRISPR/Cas9-based precise excision of SlHyPRP1 domain(s) to obtain salt stress-tolerant tomato

(2020) Mil Thi Tran et al.   PLANT CELL REPORTS

Changing local recombination patterns in Arabidopsis by CRISPR/Cas mediated chromosome engineering

(2020) Carla Schmidt et al.   Nature Communications

Clonal seeds from hybrid rice by simultaneous genome engineering of meiosis and fertilization genes

(2019) Chun Wang et al.   NATURE BIOTECHNOLOGY

Synthetic glycolate metabolism pathways stimulate crop growth and productivity in the field

(2019) Paul F. South et al.   SCIENCE

Plant Genome Engineering for Targeted Improvement of Crop Traits

(2019) Khalid E. M. Sedeek et al.   Frontiers in Plant Science

Re-evaluation of transcription factor function in tomato fruit development and ripening with CRISPR/Cas9-mutagenesis

(2019) Rufang Wang et al.   Scientific Reports

Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems

(2019) Ashot Papikian et al.   Nature Communications

Efficient induction of heritable inversions in plant genomes using the CRISPR /Cas system

(2019) Carla Schmidt et al.   PLANT JOURNAL

Mimicking natural polymorphism in eIF4E by CRISPR-Cas9 base editing is associated with resistance to potyviruses

(2019) Anna Bastet et al.   PLANT BIOTECHNOLOGY JOURNAL

Does co-transcriptional regulation of alternative splicing mediate plant stress responses?

(2019) Ibtissam Jabre et al.   NUCLEIC ACIDS RESEARCH

A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool

(2019) Xi-Wen Wang et al.   NATURE CELL BIOLOGY

One-step genome editing of elite crop germplasm during haploid induction

(2019) Timothy Kelliher et al.   NATURE BIOTECHNOLOGY

Development of a Haploid-Inducer Mediated Genome Editing System for Accelerating Maize Breeding

(2019) Baobao Wang et al.   Molecular Plant

Application of CRISPR-Cas12a temperature sensitivity for improved genome editing in rice, maize, and Arabidopsis

(2019) Aimee A. Malzahn et al.   BMC BIOLOGY

CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture

(2019) Kunling Chen et al.   Annual Review of Plant Biology

The Scope, Functions, and Dynamics of Posttranslational Protein Modifications

(2019) A. Harvey Millar et al.   Annual Review of Plant Biology

Genome Editing in Cowpea Vigna unguiculata Using CRISPR-Cas9

(2019) Jie Ji et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

De Novo Domestication: An Alternative Route toward New Crops for the Future

(2019) Alisdair R. Fernie et al.   Molecular Plant

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

Micro RNA s and new biotechnological tools for its modulation and improving stress tolerance in plants

(2019) Marcos Fernando Basso et al.   PLANT BIOTECHNOLOGY JOURNAL

CRISPR/Cas9-mediated mutagenesis of phytoene desaturase in diploid and octoploid strawberry

(2019) Fiona M. Wilson et al.   Plant Methods

Overcoming Self-Incompatibility in Diploid Potato Using CRISPR-Cas9

(2019) Felix Enciso-Rodriguez et al.   Frontiers in Plant Science

Post-Translational Modifications of Proteins Have Versatile Roles in Regulating Plant Immune Responses

(2019) Junjie Yin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration

(2019) Sanne E. Klompe et al.   NATURE

Breeding crops to feed 10 billion

(2019) Lee T. Hickey et al.   NATURE BIOTECHNOLOGY

CRISPR /Cas9 knockout of leghemoglobin genes in Lotus japonicus uncovers their synergistic roles in symbiotic nitrogen fixation

(2019) Longlong Wang et al.   NEW PHYTOLOGIST

A New Rice Breeding Method: CRISPR /Cas9 System Editing of the Xa13 Promoter to Cultivate Transgene‐free Bacterial Blight‐resistant Rice

(2019) Changyan Li et al.   PLANT BIOTECHNOLOGY JOURNAL

CRISPR /Cas9‐mediated editing of 1‐aminocyclopropane‐1‐carboxylate oxidase1 enhances Petunia flower longevity

(2019) Junping Xu et al.   PLANT BIOTECHNOLOGY JOURNAL

Integrated Genome-Scale Analysis Identifies Novel Genes and Networks Underlying Senescence in Maize

(2019) Rajandeep S Sekhon et al.   PLANT CELL

Serine/Arginine-rich protein family of splicing regulators: New approaches to study splice isoform functions

(2019) Mitchell Morton et al.   PLANT SCIENCE

RNA-guided DNA insertion with CRISPR-associated transposases

(2019) Jonathan Strecker et al.   SCIENCE

A cytosine deaminase for programmable single-base RNA editing

(2019) Omar O. Abudayyeh et al.   SCIENCE

Alternative ORFs and small ORFs: shedding light on the dark proteome

(2019) Mona Wu Orr et al.   NUCLEIC ACIDS RESEARCH

CRISPR / dC as9 platforms in plants: strategies and applications beyond genome editing

(2019) Mahdi Moradpour et al.   PLANT BIOTECHNOLOGY JOURNAL

Evolution of plant mutagenesis tools: a shifting paradigm from random to targeted genome editing

(2019) Rahul Mahadev Shelake et al.   Plant Biotechnology Reports

CRISPR-TSKO: A Technique for Efficient Mutagenesis in Specific Cell Types, Tissues, or Organs in Arabidopsis

(2019) Ward Decaestecker et al.   PLANT CELL

Metabolite Control of Translation by Conserved Peptide uORFs: The Ribosome as a Metabolite Multi-sensor

(2019) Sjors van der Horst et al.   PLANT PHYSIOLOGY

Haploid Induction and Genome Instability

(2019) Luca Comai et al.   TRENDS IN GENETICS

Reshuffling yeast chromosomes with CRISPR/Cas9

(2019) Aubin Fleiss et al.   PLoS Genetics

Targeted deletion of floral development genes in Arabidopsis with CRISPR/Cas9 using the RNA endoribonuclease Csy4 processing system

(2019) Yingzhu Liu et al.   Horticulture Research

Exploration of Plant-Microbe Interactions for Sustainable Agriculture in CRISPR Era

(2019) Rahul Mahadev Shelake et al.   Microorganisms

Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement

(2019) Jes Alexander et al.   BMC BIOLOGY

Engineering Abiotic Stress Tolerance via CRISPR-Cas mediated genome editing

(2019) Syed Adeel Zafar et al.   JOURNAL OF EXPERIMENTAL BOTANY

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

Broad-spectrum resistance to bacterial blight in rice using genome editing

(2019) Ricardo Oliva et al.   NATURE BIOTECHNOLOGY

Biological plasticity rescues target activity in CRISPR knock outs

(2019) Arne H. Smits et al.   NATURE METHODS

Engineering CRISPR/ Lb Cas12a for highly efficient, temperature‐tolerant plant gene editing

(2019) Patrick Schindele et al.   PLANT BIOTECHNOLOGY JOURNAL

New era of precision plant breeding using genome editing

(2019) Jeong-Il Kim et al.   Plant Biotechnology Reports

De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens

(2019) Wei He et al.   Nature Communications

Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems

(2019) Liang-Zhong Yang et al.   MOLECULAR CELL

Plant gene editing through de novo induction of meristems

(2019) Michael F. Maher et al.   NATURE BIOTECHNOLOGY

Multiplex CRISPR/Cas9‐mediated metabolic engineering increases soya bean isoflavone content and resistance to soya bean mosaic virus

(2019) Peipei Zhang et al.   PLANT BIOTECHNOLOGY JOURNAL

Along the Central Dogma—Controlling Gene Expression with Small Molecules

(2018) Tilman Schneider-Poetsch et al.   Annual Review of Biochemistry

Transcriptional regulation of salinity stress: role and spatio-temporal expressions of ion-transporter gene promoters

(2018) P. K. Agarwal et al.   BIOLOGIA PLANTARUM

Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation

(2018) Ahmed Mahas et al.   BIOTECHNOLOGY ADVANCES

Phenotypic novelty by CRISPR in plants

(2018) Chen Liu et al.   DEVELOPMENTAL BIOLOGY

Efficient allelic replacement in rice by gene editing: A case study of the NRT1.1B gene

(2018) Jingying Li et al.   Journal of Integrative Plant Biology

Robust Transcriptional Activation in Plants Using Multiplexed CRISPR-Act2.0 and mTALE-Act Systems

(2018) Levi G. Lowder et al.   Molecular Plant

Next-Generation Plant Metabolic Engineering, Inspired by an Ancient Chinese Irrigation System

(2018) Rao Fu et al.   Molecular Plant

cis–trans Engineering: Advances and Perspectives on Customized Transcriptional Regulation in Plants

(2018) Ankita Shrestha et al.   Molecular Plant

The Intronic cis Element SE1 Recruits trans -Acting Repressor Complexes to Repress the Expression of ELONGATED UPPERMOST INTERNODE1 in Rice

(2018) Yongyao Xie et al.   Molecular Plant

CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β-1,2-xylose and core α-1,3-fucose

(2018) Julia Jansing et al.   PLANT BIOTECHNOLOGY JOURNAL

A chromatin loop represses WUSCHEL expression in Arabidopsis

(2018) Lin Guo et al.   PLANT JOURNAL

CRISPR/Cas9-mediated mutagenesis of lncRNA1459 alters tomato fruit ripening

(2018) Ran Li et al.   PLANT JOURNAL

CRISPR/Cas9-mediated mutagenesis of the EPHEMERAL1 locus that regulates petal senescence in Japanese morning glory

(2018) Kenichi Shibuya et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Concerns regarding ‘off-target’ activity of genome editing endonucleases

(2018) Ulhas Sopanrao Kadam et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Alternative Splicing Control of Abiotic Stress Responses

(2018) Tom Laloum et al.   TRENDS IN PLANT SCIENCE

Translational Research: Exploring and Creating Genetic Diversity

(2018) Pierre Jacob et al.   TRENDS IN PLANT SCIENCE

The CRISPR tool kit for genome editing and beyond

(2018) Mazhar Adli   Nature Communications

Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity

(2018) Yang Zhao et al.   Cell Reports

Lycopene Is Enriched in Tomato Fruit by CRISPR/Cas9-Mediated Multiplex Genome Editing

(2018) Xindi Li et al.   Frontiers in Plant Science

Activation of the Transducers of Unfolded Protein Response in Plants

(2018) Ganesh M. Nawkar et al.   Frontiers in Plant Science

Plant synthetic biology could drive a revolution in biofuels and medicine

(2018) Jenny C Mortimer   EXPERIMENTAL BIOLOGY AND MEDICINE

Targeted m6A Reader Proteins To Study Epitranscriptomic Regulation of Single RNAs

(2018) Simone Rauch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Application of CRISPR/Cas9 to Tragopogon (Asteraceae), an evolutionary model for the study of polyploidy

(2018) Shengchen Shan et al.   Molecular Ecology Resources

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

(2018) Shakked O. Halperin et al.   NATURE

Genome editing of upstream open reading frames enables translational control in plants

(2018) Huawei Zhang et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9-mediated efficient targeted mutagenesis of RAS in Salvia miltiorrhiza

(2018) Zheng Zhou et al.   PHYTOCHEMISTRY

CRISPR-Cas guides the future of genetic engineering

(2018) Gavin J. Knott et al.   SCIENCE

Manipulating mRNA splicing by base editing in plants

(2018) Chenxiao Xue et al.   Science China-Life Sciences

Alternative Splicing as a Regulator of Early Plant Development

(2018) Dóra Szakonyi et al.   Frontiers in Plant Science

Monitoring of Plant Protein Post-translational Modifications Using Targeted Proteomics

(2018) Borjana Arsova et al.   Frontiers in Plant Science

CRISPR/Cas9-Mediated Deletion of Large Genomic Fragments in Soybean

(2018) Yupeng Cai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sedoheptulose-1,7-Bisphosphatase is Involved in Methyl Jasmonate- and Dark-Induced Leaf Senescence in Tomato Plants

(2018) Fei Ding et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A male-expressed rice embryogenic trigger redirected for asexual propagation through seeds

(2018) Imtiyaz Khanday et al.   NATURE

Domestication of wild tomato is accelerated by genome editing

(2018) Tingdong Li et al.   NATURE BIOTECHNOLOGY

De novo domestication of wild tomato using genome editing

(2018) Agustin Zsögön et al.   NATURE BIOTECHNOLOGY

Gene disruption through base editing-induced mRNA mis-splicing in plants

(2018) Zhenxiang Li et al.   NEW PHYTOLOGIST

Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis

(2018) Rashid Aman et al.   Viruses-Basel

Contribution of major FLM isoforms to temperature-dependent flowering in Arabidopsis thaliana

(2017) Giovanna Capovilla et al.   JOURNAL OF EXPERIMENTAL BOTANY

Suppression or knockout of SaF /SaM overcomes the Sa -mediated hybrid male sterility in rice

(2017) Yongyao Xie et al.   Journal of Integrative Plant Biology

Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28

(2017) Aaron A. Smargon et al.   MOLECULAR CELL

Interspecific Hybrid Sterility in Rice Is Mediated by  OgTPR1 at the S1 Locus Encoding a Peptidase-like Protein

(2017) Yongyao Xie et al.   Molecular Plant

RNA targeting with CRISPR–Cas13

(2017) Omar O. Abudayyeh et al.   NATURE

uORF-mediated translation allows engineered plant disease resistance without fitness costs

(2017) Guoyong Xu et al.   NATURE

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

Targeted mutagenesis in tetraploid switchgrass (Panicum virgatum L.) using CRISPR/Cas9

(2017) Yang Liu et al.   PLANT BIOTECHNOLOGY JOURNAL

Multiplexed CRISPR/Cas9-mediated metabolic engineering of γ-aminobutyric acid levels in Solanum lycopersicum

(2017) Rui Li et al.   PLANT BIOTECHNOLOGY JOURNAL

Engineering canker-resistant plants through CRISPR/Cas9-targeted editing of the susceptibility gene CsLOB1 promoter in citrus

(2017) Aihong Peng et al.   PLANT BIOTECHNOLOGY JOURNAL

Significant enhancement of fatty acid composition in seeds of the allohexaploid, Camelina sativa , using CRISPR/Cas9 gene editing

(2017) Wen Zhi Jiang et al.   PLANT BIOTECHNOLOGY JOURNAL

Genome editing of the disease susceptibility gene CsLOB1 in citrus confers resistance to citrus canker

(2017) Hongge Jia et al.   PLANT BIOTECHNOLOGY JOURNAL

An InDel in the Promoter of Al-ACTIVATED MALATE TRANSPORTER9 Selected during Tomato Domestication Determines Fruit Malate Contents and Aluminum Tolerance

(2017) Jie Ye et al.   PLANT CELL

A multi-purpose toolkit to enable advanced genome engineering in plants

(2017) Tomas Cermak et al.   PLANT CELL

Deletion of a target gene in Indica rice via CRISPR/Cas9

(2017) Ying Wang et al.   PLANT CELL REPORTS

Translation regulation in plants: an interesting past, an exciting present and a promising future

(2017) Catharina Merchante et al.   PLANT JOURNAL

From classical mutagenesis to nuclease-based breeding - directing natural DNA repair for a natural end-product

(2017) Michael Pacher et al.   PLANT JOURNAL

Evaluation of the mature grain phytase candidate HvPAPhy_a gene in barley (Hordeum vulgare L.) using CRISPR/Cas9 and TALENs

(2017) Inger B. Holme et al.   PLANT MOLECULAR BIOLOGY

A uORF Represses the Transcription Factor AtHB1 in Aerial Tissues to Avoid a Deleterious Phenotype

(2017) Pamela A. Ribone et al.   PLANT PHYSIOLOGY

RNA editing with CRISPR-Cas13

(2017) David B. T. Cox et al.   SCIENCE

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Accelerating the Domestication of New Crops: Feasibility and Approaches

(2017) Jeppe Thulin Østerberg et al.   TRENDS IN PLANT SCIENCE

Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping

(2017) Stefanie L. Morgan et al.   Nature Communications

60 years ago, Francis Crick changed the logic of biology

(2017) Matthew Cobb   PLOS BIOLOGY

Spatiotemporal Expression and Substrate Specificity Analysis of the Cucumber SWEET Gene Family

(2017) Yaxin Li et al.   Frontiers in Plant Science

Building a Genetic Manipulation Tool Box for Orchid Biology: Identification of Constitutive Promoters and Application of CRISPR/Cas9 in the Orchid, Dendrobium officinale

(2017) Ling Kui et al.   Frontiers in Plant Science

Genome Editing in Cotton with the CRISPR/Cas9 System

(2017) Wei Gao et al.   Frontiers in Plant Science

Post-translational Modifications in Regulation of Chloroplast Function: Recent Advances

(2017) Magda Grabsztunowicz et al.   Frontiers in Plant Science

Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 Cells by a Multiplex CRISPR/Cas9 Strategy Results in Glycoproteins without Plant-Specific Glycans

(2017) Sébastien Mercx et al.   Frontiers in Plant Science

CRISPR-Cas9 Based Genome Editing Reveals New Insights into MicroRNA Function and Regulation in Rice

(2017) Jianping Zhou et al.   Frontiers in Plant Science

Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza

(2017) Bin Li et al.   Scientific Reports

Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion

(2017) Vladimir Nekrasov et al.   Scientific Reports

Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology

(2016) Jeyabharathy Chandrasekaran et al.   MOLECULAR PLANT PATHOLOGY

Gene-edited CRISPR mushroom escapes US regulation

(2016) Emily Waltz   NATURE

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library

(2016) Shiyou Zhu et al.   NATURE BIOTECHNOLOGY

Genetic drift, selection and the evolution of the mutation rate

(2016) Michael Lynch et al.   NATURE REVIEWS GENETICS

ARGOS8 variants generated by CRISPR-Cas9 improve maize grain yield under field drought stress conditions

(2016) Jinrui Shi et al.   PLANT BIOTECHNOLOGY JOURNAL

Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts

(2016) Mariette Andersson et al.   PLANT CELL REPORTS

Generation of chromosomal deletions in dicotyledonous plants employing a user-friendly genome editing toolkit

(2016) Jana Ordon et al.   PLANT JOURNAL

Synthetic strategies for plant signalling studies: molecular toolbox and orthogonal platforms

(2016) Justine Braguy et al.   PLANT JOURNAL

Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems

(2016) K. Nishida et al.   SCIENCE

Manipulating the Biosynthesis of Bioactive Compound Alkaloids for Next-Generation Metabolic Engineering in Opium Poppy Using CRISPR-Cas 9 Genome Editing Technology

(2016) Yagiz Alagoz et al.   Scientific Reports

Quantitative Genetics Identifies Cryptic Genetic Variation Involved in the Paternal Regulation of Seed Development

(2016) Nuno D. Pires et al.   PLoS Genetics

A new synthetic biology approach allows transfer of an entire metabolic pathway from a medicinal plant to a biomass crop

(2016) Paulina Fuentes et al.   eLife

An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design

(2016) Yongping Zhao et al.   Scientific Reports

Targeting cellular mRNAs translation by CRISPR-Cas9

(2016) Yuchen Liu et al.   Scientific Reports

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

(2015) Bernd Zetsche et al.   CELL

Stress-induced structural changes in plant chromatin

(2015) Aline V Probst et al.   CURRENT OPINION IN PLANT BIOLOGY

Sequence determinants of improved CRISPR sgRNA design

(2015) Han Xu et al.   GENOME RESEARCH

Crop Epigenomics: Identifying, Unlocking, and Harnessing Cryptic Variation in Crop Genomes

(2015) Lexiang Ji et al.   Molecular Plant

A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants

(2015) Xingliang Ma et al.   Molecular Plant

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

(2015) Silvana Konermann et al.   NATURE

Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display

(2015) David M Shechner et al.   NATURE METHODS

Highly efficient Cas9-mediated transcriptional programming

(2015) Alejandro Chavez et al.   NATURE METHODS

A novel strategy to produce sweeter tomato fruits with high sugar contents by fruit-specific expression of a single bZIP transcription factor gene

(2015) G. H. M. Sagor et al.   PLANT BIOTECHNOLOGY JOURNAL

Modification of the PthA4 effector binding elements in Type I CsLOB1 promoter using Cas9/sgRNA to produce transgenic Duncan grapefruit alleviating XccΔpthA4:dCsLOB1.3 infection

(2015) Hongge Jia et al.   PLANT BIOTECHNOLOGY JOURNAL

Identification of a regulatory element responsible for salt induction of rice OsRAV2 through ex situ and in situ promoter analysis

(2015) Yong-Bo Duan et al.   PLANT MOLECULAR BIOLOGY

Living to Die and Dying to Live: The Survival Strategy behind Leaf Senescence

(2015) Jos H.M. Schippers et al.   PLANT PHYSIOLOGY

A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation

(2015) Levi G. Lowder et al.   PLANT PHYSIOLOGY

Cas9-mediated targeting of viral RNA in eukaryotic cells

(2015) Aryn A. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system

(2015) Kabin Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allele mining and enhanced genetic recombination for rice breeding

(2015) Hei Leung et al.   Rice

Interactions between circadian clocks and photosynthesis for the temporal and spatial coordination of metabolism

(2015) Antony N. Dodd et al.   Frontiers in Plant Science

Post-transcriptional and post-translational regulations of drought and heat response in plants: a spider’s web of mechanisms

(2015) Davide Guerra et al.   Frontiers in Plant Science

DNA damage and repair in plants – from models to crops

(2015) Vasilissa Manova et al.   Frontiers in Plant Science

Conferring resistance to geminiviruses with the CRISPR–Cas prokaryotic immune system

(2015) Nicholas J. Baltes et al.   Nature Plants

A CRISPR-based approach for proteomic analysis of a single genomic locus

(2014) Zachary J Waldrip et al.   Epigenetics

The stay-green trait

(2014) Howard Thomas et al.   JOURNAL OF EXPERIMENTAL BOTANY

Programmable RNA recognition and cleavage by CRISPR/Cas9

(2014) Mitchell R. O’Connell et al.   NATURE

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

(2014) Danilo Maddalo et al.   NATURE

Increasing CO2 threatens human nutrition

(2014) Samuel S. Myers et al.   NATURE

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

(2014) Yanpeng Wang et al.   NATURE BIOTECHNOLOGY

Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice

(2014) Huanbin Zhou et al.   NUCLEIC ACIDS RESEARCH

The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation

(2014) Hui Zhang et al.   PLANT BIOTECHNOLOGY JOURNAL

A Brief History of Epigenetics

(2014) G. Felsenfeld   Cold Spring Harbor Perspectives in Biology

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

(2013) Baohui Chen et al.   CELL

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Metabolic engineering of yeast for production of fuels and chemicals

(2013) Jens Nielsen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Plant leaf senescence and death - regulation by multiple layers of control and implications for aging in general

(2013) H. R. Woo et al.   JOURNAL OF CELL SCIENCE

Self-processing of ribozyme-flanked RNAs into guide RNAsin vitroandin vivofor CRISPR-mediated genome editing

(2013) Yangbin Gao et al.   Journal of Integrative Plant Biology

RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System

(2013) Kabin Xie et al.   Molecular Plant

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

Evidence of cryptic introgression in tomato (Solanum lycopersicum L.) based on wild tomato species alleles

(2012) Joanne A Labate et al.   BMC PLANT BIOLOGY

Modulation of endogenous pathways enhances bioethanol yield and productivity in Escherichia coli

(2012) Neha Munjal et al.   Microbial Cell Factories

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

A single nucleotide polymorphism at the Vrn-D1 promoter region in common wheat is associated with vernalization response

(2012) Jing Zhang et al.   THEORETICAL AND APPLIED GENETICS

Alternative splicing in plants – coming of age

(2012) Naeem H. Syed et al.   TRENDS IN PLANT SCIENCE

Allele mining in crops: Prospects and potentials

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