Multiplexed CRISPR/Cas9-mediated metabolic engineering of γ-aminobutyric acid levels in Solanum lycopersicum

Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza

(2017) Bin Li et al.   Scientific Reports

Advances and perspectives on the use of CRISPR/Cas9 systems in plant genomics research

(2016) Degao Liu et al.   CURRENT OPINION IN PLANT BIOLOGY

Activating glutamate decarboxylase activity by removing the autoinhibitory domain leads to hyper γ-aminobutyric acid (GABA) accumulation in tomato fruit

(2016) Mariko Takayama et al.   PLANT CELL REPORTS

Plant GABA: Not Just a Metabolite

(2016) Alan W. Bown et al.   TRENDS IN PLANT SCIENCE

Opportunities for Products of New Plant Breeding Techniques

(2016) Jan G. Schaart et al.   TRENDS IN PLANT SCIENCE

Manipulating the Biosynthesis of Bioactive Compound Alkaloids for Next-Generation Metabolic Engineering in Opium Poppy Using CRISPR-Cas 9 Genome Editing Technology

(2016) Yagiz Alagoz et al.   Scientific Reports

Plant Metabolic Engineering Strategies for the Production of Pharmaceutical Terpenoids

(2016) Xu Lu et al.   Frontiers in Plant Science

CRISPR/Cas9-mediated efficient and heritable targeted mutagenesis in tomato plants in the first and later generations

(2016) Changtian Pan et al.   Scientific Reports

The CRISPR/Cas9 system for plant genome editing and beyond

(2015) Luisa Bortesi et al.   BIOTECHNOLOGY ADVANCES

Targeted genome modifications in soybean with CRISPR/Cas9

(2015) Thomas B Jacobs et al.   BMC BIOTECHNOLOGY

Editing plant genomes with CRISPR/Cas9

(2015) Khaoula Belhaj et al.   CURRENT OPINION IN BIOTECHNOLOGY

Genome editing in plants via designed zinc finger nucleases

(2015) Joseph F. Petolino   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae

(2015) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants

(2015) Xingliang Ma et al.   Molecular Plant

Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system

(2015) Shaohui Wang et al.   PLANT CELL REPORTS

A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis

(2015) Zhengjing Zhang et al.   PLANT CELL REPORTS

A tonoplast Glu/Asp/GABA exchanger that affects tomato fruit amino acid composition

(2015) Christopher J. Snowden et al.   PLANT JOURNAL

GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters

(2015) Sunita A. Ramesh et al.   Nature Communications

Modulation of GABA and resting state functional connectivity by transcranial direct current stimulation

(2015) Velicia Bachtiar et al.   eLife

How and why does tomato accumulate a large amount of GABA in the fruit?

(2015) Mariko Takayama et al.   Frontiers in Plant Science

CRISPR/Cas9-Mediated Genome Editing in Soybean Hairy Roots

(2015) Yupeng Cai et al.   PLoS One

TALEN-Based Mutagenesis of Lipoxygenase LOX3 Enhances the Storage Tolerance of Rice (Oryza sativa) Seeds

(2015) Lei Ma et al.   PLoS One

A CRISPR view of development

(2014) Melissa M. Harrison et al.   GENES & DEVELOPMENT

Exogenous γ-aminobutyric acid (GABA) affects pollen tube growth via modulating putative Ca2+-permeable membrane channels and is coupled to negative regulation on glutamate decarboxylase

(2014) Guang-Hui Yu et al.   JOURNAL OF EXPERIMENTAL BOTANY

An efficient TALEN mutagenesis system in rice

(2014) Kunling Chen et al.   METHODS

Genome editing in rice and wheat using the CRISPR/Cas system

(2014) Qiwei Shan et al.   Nature Protocols

Multigene Knockout Utilizing Off-Target Mutations of the CRISPR/Cas9 System in Rice

(2014) Masaki Endo et al.   PLANT AND CELL PHYSIOLOGY

DNA Replicons for Plant Genome Engineering

(2014) N. J. Baltes et al.   PLANT CELL

Virus-induced gene silencing reveals control of reactive oxygen species accumulation and salt tolerance in tomato byγ-aminobutyric acid metabolic pathway

(2014) HEXIGEDULENG BAO et al.   PLANT CELL AND ENVIRONMENT

Efficient Gene Editing in Tomato in the First Generation Using the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated9 System

(2014) C. Brooks et al.   PLANT PHYSIOLOGY

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

The history of tomato: From domestication to biopharming

(2013) Véronique Bergougnoux   BIOTECHNOLOGY ADVANCES

Suppression of γ-Aminobutyric Acid (GABA) Transaminases Induces Prominent GABA Accumulation, Dwarfism and Infertility in the Tomato (Solanum lycopersicum L.)

(2013) Satoshi Koike et al.   PLANT AND CELL PHYSIOLOGY

The role of GABAergic modulation in motor function related neuronal network activity

(2011) S.D. Hall et al.   NEUROIMAGE

GABA Accumulation Causes Cell Elongation Defects and a Decrease in Expression of Genes Encoding Secreted and Cell Wall-Related Proteins in Arabidopsis thaliana

(2011) Hugues Renault et al.   PLANT AND CELL PHYSIOLOGY

The Arabidopsis pop2-1 mutant reveals the involvement of GABA transaminase in salt stress tolerance

(2010) Hugues Renault et al.   BMC PLANT BIOLOGY

Antihypertensive Effect of a γ-Aminobutyric Acid Rich Tomato Cultivar ‘DG03-9’ in Spontaneously Hypertensive Rats

(2009) Mineka Yoshimura et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of exogenous GABA on gene expression ofCaragana intermediaroots under NaCl stress: regulatory roles for H2O2and ethylene production

(2009) SHENG-QING SHI et al.   PLANT CELL AND ENVIRONMENT

Biochemical Mechanism on GABA Accumulation During Fruit Development in Tomato

(2008) Takashi Akihiro et al.   PLANT AND CELL PHYSIOLOGY

Mutants of GABA Transaminase (POP2) Suppress the Severe Phenotype of succinic semialdehyde dehydrogenase (ssadh) Mutants in Arabidopsis

(2008) Frank Ludewig et al.   PLoS One

Highway or byway: the metabolic role of the GABA shunt in plants

(2007) Aaron Fait et al.   TRENDS IN PLANT SCIENCE