CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells

(2016) Yunqing Ma et al.   NATURE METHODS

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

(2016) Gaelen T Hess et al.   NATURE METHODS

Whole-organism lineage tracing by combinatorial and cumulative genome editing

(2016) Aaron McKenna et al.   SCIENCE

Rationally engineered Cas9 nucleases with improved specificity

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Development of potent in vivo mutagenesis plasmids with broad mutational spectra

(2015) Ahmed H. Badran et al.   Nature Communications

Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA

(2014) Cosimo Ducani et al.   NUCLEIC ACIDS RESEARCH

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

A system for the continuous directed evolution of biomolecules

(2011) Kevin M. Esvelt et al.   NATURE

Functional and molecular analysis of Escherichia coli strains lacking multiple DEAD-box helicases

(2010) K. L. Jagessar et al.   RNA

Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis

(2009) B. M. Hall et al.   BIOINFORMATICS

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Optimization of DNA polymerase mutation rates during bacterial evolution

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