Reshuffling yeast chromosomes with CRISPR/Cas9

Long-read sequencing data analysis for yeasts

(2018) Jia-Xing Yue et al.   Nature Protocols

A history of genome editing in Saccharomyces cerevisiae

(2018) William G. Alexander   YEAST

History of genome editing in yeast

(2018) Marcin G. Fraczek et al.   YEAST

Heterozygous diploid and interspecies SCRaMbLEing

(2018) Michael J. Shen et al.   Nature Communications

L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast

(2018) Lena Hochrein et al.   Nature Communications

Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaks

(2018) Nobuhiko Muramoto et al.   Nature Communications

Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome

(2018) B. A. Blount et al.   Nature Communications

Precise control of SCRaMbLE in synthetic haploid and diploid yeast

(2018) Bin Jia et al.   Nature Communications

Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast

(2018) Jingchuan Luo et al.   NATURE

Creating a functional single-chromosome yeast

(2018) Yangyang Shao et al.   NATURE

Connecting genome structural variation with complex traits in crop plants

(2018) Iulian Gabur et al.   THEORETICAL AND APPLIED GENETICS

Contrasting evolutionary genome dynamics between domesticated and wild yeasts

(2017) Jia-Xing Yue et al.   NATURE GENETICS

The initiation, propagation and dynamics of CRISPR-SpyCas9 R-loop complex

(2017) Yan Zeng et al.   NUCLEIC ACIDS RESEARCH

CRISPR-Cas9–guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells

(2017) Fabio Vanoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast

(2017) Daniel C. Jeffares et al.   Nature Communications

Widespread Impact of Chromosomal Inversions on Gene Expression Uncovers Robustness via Phenotypic Buffering

(2016) Samina Naseeb et al.   MOLECULAR BIOLOGY AND EVOLUTION

Applications of CRISPR Genome Engineering in Cell Biology

(2016) Fangyuan Wang et al.   TRENDS IN CELL BIOLOGY

CRISPR-PCS: a powerful new approach to inducing multiple chromosome splitting in Saccharomyces cerevisiae

(2016) Yu Sasano et al.   Scientific Reports

CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae

(2015) Robert Mans et al.   FEMS YEAST RESEARCH

SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes

(2015) Yue Shen et al.   GENOME RESEARCH

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae

(2015) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

Chromosomal Rearrangements as a Major Mechanism in the Onset of Reproductive Isolation in Saccharomyces cerevisiae

(2014) Jing Hou et al.   CURRENT BIOLOGY

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

(2014) Danilo Maddalo et al.   NATURE

Landscape of target:guide homology effects on Cas9-mediated cleavage

(2014) Becky Xu Hua Fu et al.   NUCLEIC ACIDS RESEARCH

Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast

(2014) Guy-Franck Richard et al.   PLoS One

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Total Synthesis of a Functional Designer Eukaryotic Chromosome

(2014) N. Annaluru et al.   SCIENCE

Homology-Integrated CRISPR–Cas (HI-CRISPR) System for One-Step Multigene Disruption in Saccharomyces cerevisiae

(2014) Zehua Bao et al.   ACS Synthetic Biology

Cancer translocations in human cells induced by zinc finger and TALE nucleases

(2013) M. Piganeau et al.   GENOME RESEARCH

Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish

(2013) An Xiao et al.   NUCLEIC ACIDS RESEARCH

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Genome architecture is a selectable trait that can be maintained by antagonistic pleiotropy

(2013) Ana Teresa Avelar et al.   Nature Communications

Impact of Chromosomal Inversions on the Yeast DAL Cluster

(2012) Samina Naseeb et al.   PLoS One

Phenotypic variability and genetic susceptibility to genomic disorders

(2010) S. Girirajan et al.   HUMAN MOLECULAR GENETICS

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

(2010) Anastasia Baryshnikova et al.   NATURE METHODS

Chromosomal translocations induced at specified loci in human stem cells

(2009) E. Brunet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Double-strand breaks associated with repetitive DNA can reshape the genome

(2008) J. L. Argueso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms

(2008) Celia Payen et al.   PLoS Genetics