Molecular Mimicry: a Paradigm of Host-Microbe Coevolution Illustrated by Legionella
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Title
Molecular Mimicry: a Paradigm of Host-Microbe Coevolution Illustrated by Legionella
Authors
Keywords
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Journal
mBio
Volume 11, Issue 5, Pages -
Publisher
American Society for Microbiology
Online
2020-10-05
DOI
10.1128/mbio.01201-20
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Note: Only part of the references are listed.- The bacterial deubiquitinase Ceg23 regulates the association of Lys-63–linked polyubiquitin molecules on the Legionella phagosome
- (2020) Kelong Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterizing the microbiomes of Antarctic sponges: a functional metagenomic approach
- (2020) Mario Moreno-Pino et al. Scientific Reports
- Phosphoinositides and the Fate of Legionella in Phagocytes
- (2020) A. Leoni Swart et al. Frontiers in Immunology
- Combinatorial selection in amoebal hosts drives the evolution of the human pathogen Legionella pneumophila
- (2020) Jason M. Park et al. Nature Microbiology
- Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector
- (2020) Christopher Price et al. Cell Host & Microbe
- A Legionella effector kinase is activated by host inositol hexakisphosphate
- (2020) Anju Sreelatha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets
- (2020) A. Leoni Swart et al. mBio
- Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex
- (2020) Hyunmin Kim et al. Nature Communications
- TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation
- (2020) Pei-Chung Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mimicry of Short Linear Motifs by Bacterial Pathogens: A Drugging Opportunity
- (2020) Hugo Sámano-Sánchez et al. TRENDS IN BIOCHEMICAL SCIENCES
- More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells
- (2019) Laura Gomez-Valero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis
- (2019) Steven M. Moss et al. Cell Host & Microbe
- The Other Side of the Coin: What Beneficial Microbes Can Teach Us about Pathogenic Potential
- (2019) Travis J. Wiles et al. JOURNAL OF MOLECULAR BIOLOGY
- Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases
- (2019) Miles H. Black et al. SCIENCE
- A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling
- (2019) Muyang Wan et al. Nature Microbiology
- Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella
- (2019) Laure Gomez-Valero et al. MICROBES AND INFECTION
- Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
- (2019) Ninghai Gan et al. NATURE
- Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation
- (2019) Sagar Bhogaraju et al. NATURE
- Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex
- (2019) Juanita Von Dwingelo et al. mBio
- Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella
- (2019) Sonia Mondino et al. Annual Review of Pathology-Mechanisms of Disease
- Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
- (2019) Donghyuk Shin et al. MOLECULAR CELL
- Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ
- (2019) Alan Sulpizio et al. eLife
- LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth
- (2018) Tomoko Kubori et al. CELLULAR MICROBIOLOGY
- Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?
- (2018) Pedro Escoll et al. FEBS Journal
- TheLegionella pneumophilaeffector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways
- (2018) Andrew T. Quaile et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Legionella pneumophilaeffector Lem4 is a membrane-associated protein tyrosine phosphatase
- (2018) Ksenia Beyrakhova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection
- (2018) Maren Kirstin Schuhmacher et al. JOURNAL OF MOLECULAR BIOLOGY
- A Legionella pneumophila amylase is essential for intracellular replication in human macrophages and amoebae
- (2018) Ashley Best et al. Scientific Reports
- RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases
- (2018) Yi-Han Lin et al. PLoS Pathogens
- The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection
- (2018) Pei-Chung Lee et al. Cell Host & Microbe
- Revisiting Bacterial Ubiquitin Ligase Effectors: Weapons for Host Exploitation
- (2018) Antonio Pisano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase
- (2018) Nadezhda Levanova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Uncovering the Structural Basis of a New Twist in Protein Ubiquitination
- (2018) Kedar Puvar et al. TRENDS IN BIOCHEMICAL SCIENCES
- Identification and characterization of a large family of superbinding bacterial SH2 domains
- (2018) Tomonori Kaneko et al. Nature Communications
- Comparative Genomic Analysis of Acanthamoeba Endosymbionts Highlights the Role of Amoebae as a “Melting Pot” Shaping the Rickettsiales Evolution
- (2017) Zhang Wang et al. Genome Biology and Evolution
- Expression of eukaryotic-like protein in the microbiome of sponges
- (2017) C. Díez-Vives et al. MOLECULAR ECOLOGY
- Free-Living Amoebae as Hosts for and Vectors of Intracellular Microorganisms with Public Health Significance
- (2017) Carsten Balczun et al. Viruses-Basel
- Hijacking of the Host Ubiquitin Network by Legionella pneumophila
- (2017) Jiazhang Qiu et al. Frontiers in Cellular and Infection Microbiology
- From Many Hosts, One Accidental Pathogen: The Diverse Protozoan Hosts of Legionella
- (2017) David K. Boamah et al. Frontiers in Cellular and Infection Microbiology
- The Multifaceted Role of SNARE Proteins in Membrane Fusion
- (2017) Jing Han et al. Frontiers in Physiology
- Divergent evolution of Di-lysine ER retention vs. farnesylation motif-mediated anchoring of the AnkB virulence effector to the Legionella-containing vacuolar membrane
- (2017) John D. Perpich et al. Scientific Reports
- Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
- (2016) Sagar Bhogaraju et al. CELL
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- (2016) Alexander W Ensminger CURRENT OPINION IN MICROBIOLOGY
- Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila
- (2016) Malene L Urbanus et al. Molecular Systems Biology
- Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
- (2016) Jiazhang Qiu et al. NATURE
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- (2016) David Burstein et al. NATURE GENETICS
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- (2016) Xingqi Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Monica Rolando et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Emine Guven-Maiorov et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
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- (2016) Eva M. Campodonico et al. PLoS One
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- (2015) Ernest C. So et al. CANADIAN JOURNAL OF MICROBIOLOGY
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- (2015) Nathan P. King et al. CELLULAR MICROBIOLOGY
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- (2015) Pedro Escoll et al. NATURE REVIEWS MICROBIOLOGY
- Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination
- (2015) Michael J. Sheedlo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila
- (2015) Andrew T. Quaile et al. STRUCTURE
- How pathogens use linear motifs to perturb host cell networks
- (2015) Allegra Via et al. TRENDS IN BIOCHEMICAL SCIENCES
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- (2015) Céline Michard et al. mBio
- The structure of Legionella pneumophila LegK4 type four secretion system (T4SS) effector reveals a novel dimeric eukaryotic-like kinase
- (2015) Ali Flayhan et al. Scientific Reports
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- (2015) Rekha Seshadri et al. Scientific Reports
- The Legionella pneumophila Effector Protein, LegC7, Alters Yeast Endosomal Trafficking
- (2015) Kevin M. O’Brien et al. PLoS One
- Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication ofLegionella pneumophila
- (2014) Patrice Riedmaier et al. BIOCHEMICAL JOURNAL
- Icm/Dot-dependent inhibition of phagocyte migration byLegionellais antagonized by a translocated Ran GTPase activator
- (2014) Sylvia Simon et al. CELLULAR MICROBIOLOGY
- Arfs at a Glance
- (2014) C. L. Jackson et al. JOURNAL OF CELL SCIENCE
- Legionella pneumophila type IV effectors hijack the transcription and translation machinery of the host cell
- (2014) Monica Rolando et al. TRENDS IN CELL BIOLOGY
- Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires¿ disease
- (2014) Laura Gomez-Valero et al. GENOME BIOLOGY
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- (2014) Raúl Alvarez-Venegas Frontiers in Genetics
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- (2013) Monica Rolando et al. Cell Host & Microbe
- SET-domain bacterial effectors target heterochromatin protein 1 to activate host rDNA transcription
- (2013) Ting Li et al. EMBO REPORTS
- Anthrax SET Protein
- (2013) Shiraz Mujtaba et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ankyrin-repeat proteins from sponge symbionts modulate amoebal phagocytosis
- (2013) Mary T. H. D. Nguyen et al. MOLECULAR ECOLOGY
- Regulation of Small GTPases by GEFs, GAPs, and GDIs
- (2013) Jacqueline Cherfils et al. PHYSIOLOGICAL REVIEWS
- LegC3, an Effector Protein from Legionella pneumophila, Inhibits Homotypic Yeast Vacuole Fusion In Vivo and In Vitro
- (2013) Terry L. Bennett et al. PLoS One
- Molecular Mechanisms of SH2- and PTB-Domain-Containing Proteins in Receptor Tyrosine Kinase Signaling
- (2013) M. J. Wagner et al. Cold Spring Harbor Perspectives in Biology
- Genome Dynamics in Legionella: The Basis of Versatility and Adaptation to Intracellular Replication
- (2013) L. Gomez-Valero et al. Cold Spring Harbor Perspectives in Medicine
- Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection
- (2013) Eva Rothmeier et al. PLoS Pathogens
- The Ubiquitin System, an Immense Realm
- (2012) Alexander Varshavsky Annual Review of Biochemistry
- When bacteria target the nucleus: the emerging family of nucleomodulins
- (2012) Hélène Bierne et al. CELLULAR MICROBIOLOGY
- Cellular function and molecular structure of ecto-nucleotidases
- (2012) Herbert Zimmermann et al. Purinergic Signalling
- Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection
- (2012) Pavel Dolezal et al. PLoS Pathogens
- Identification of Two Legionella pneumophila Effectors that Manipulate Host Phospholipids Biosynthesis
- (2012) Ram Viner et al. PLoS Pathogens
- Insight into cross-talk between intra-amoebal pathogens
- (2011) Gregory Gimenez et al. BMC GENOMICS
- Molecular Mimicry as a Mechanism of Autoimmune Disease
- (2011) Matthew F. Cusick et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Protein Kinase LegK2 Is a Type IV Secretion System Effector Involved in Endoplasmic Reticulum Recruitment and Intracellular Replication of Legionella pneumophila
- (2011) Eva Hervet et al. INFECTION AND IMMUNITY
- GamA is a eukaryotic-like glucoamylase responsible for glycogen- and starch-degrading activity of Legionella pneumophila
- (2011) Vroni Herrmann et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- The Coxiella burnetii Cryptic Plasmid Is Enriched in Genes Encoding Type IV Secretion System Substrates
- (2011) D. E. Voth et al. JOURNAL OF BACTERIOLOGY
- Genome-Wide Identification of Molecular Mimicry Candidates in Parasites
- (2011) Philipp Ludin et al. PLoS One
- Host Proteasomal Degradation Generates Amino Acids Essential for Intracellular Bacterial Growth
- (2011) C. T. D. Price et al. SCIENCE
- Comparative and Functional Genomics of Legionella Identified Eukaryotic Like Proteins as Key Players in Host?Pathogen Interactions
- (2011) Laura Gomez-Valero et al. Frontiers in Microbiology
- The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication
- (2010) M. Lomma et al. CELLULAR MICROBIOLOGY
- Molecular Pathogenesis of Infections Caused by Legionella pneumophila
- (2010) H. J. Newton et al. CLINICAL MICROBIOLOGY REVIEWS
- Genome analysis of microorganisms living in amoebae reveals a melting pot of evolution
- (2010) Claire Moliner et al. FEMS MICROBIOLOGY REVIEWS
- The origins of eukaryotic-like proteins in Legionella pneumophila
- (2010) Mor N. Lurie-Weinberger et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization ofLegionella pneumophilaEffector Proteins
- (2010) Stanimir S. Ivanov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector ofLegionella pneumophila
- (2010) Christopher T.D. Price et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Effective--a database of predicted secreted bacterial proteins
- (2010) M.-A. Jehl et al. NUCLEIC ACIDS RESEARCH
- Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease
- (2010) Christel Cazalet et al. PLoS Genetics
- Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector
- (2010) Tomoko Kubori et al. PLoS Pathogens
- Histone Methylation by NUE, a Novel Nuclear Effector of the Intracellular Pathogen Chlamydia trachomatis
- (2010) Meghan E. Pennini et al. PLoS Pathogens
- ALegionellaeffector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria
- (2009) Elena Degtyar et al. CELLULAR MICROBIOLOGY
- The Genome of the Amoeba Symbiont "Candidatus Amoebophilus asiaticus" Reveals Common Mechanisms for Host Cell Interaction among Amoeba-Associated Bacteria
- (2009) S. Schmitz-Esser et al. JOURNAL OF BACTERIOLOGY
- Legionella, Protozoa, and Biofilms: Interactions Within Complex Microbial Systems
- (2009) Michael Taylor et al. MICROBIAL ECOLOGY
- The evolutionary conundrum of pathogen mimicry
- (2009) Nels C. Elde et al. NATURE REVIEWS MICROBIOLOGY
- A Legionella type IV effector activates the NF- B pathway by phosphorylating the I B family of inhibitors
- (2009) J. Ge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Mimicry by an F-Box Effector of Legionella pneumophila Hijacks a Conserved Polyubiquitination Machinery within Macrophages and Protozoa
- (2009) Christopher T. Price et al. PLoS Pathogens
- The RCC1 superfamily: From genes, to function, to disease
- (2008) Ouadah Hadjebi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Proteomic Characterization of the Whole Secretome of Legionella pneumophila and Functional Analysis of Outer Membrane Vesicles
- (2008) F. Galka et al. INFECTION AND IMMUNITY
- Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase fromLegionella pneumophila
- (2008) Fiona M. Sansom et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Dot/Icm-translocated ankyrin protein ofLegionella pneumophilais required for intracellular proliferation within human macrophages and protozoa
- (2008) Souhaila Al-Khodor et al. MOLECULAR MICROBIOLOGY
- Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions
- (2008) Tomoko Kubori et al. MOLECULAR MICROBIOLOGY
- I never met a microbe I didn't like
- (2008) Stanley Falkow NATURE MEDICINE
- The Legionella pneumophila replication vacuole: making a cosy niche inside host cells
- (2008) Ralph R. Isberg et al. NATURE REVIEWS MICROBIOLOGY
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