The structure of Legionella pneumophila LegK4 type four secretion system (T4SS) effector reveals a novel dimeric eukaryotic-like kinase

Formation of a pathogen vacuole according toLegionella pneumophila: how to kill one bird with many stones

(2015) Ivo Finsel et al.   CELLULAR MICROBIOLOGY

Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host

(2015) Andrey M. Grishin et al.   PROTEIN SCIENCE

The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway

(2015) Céline Michard et al.   mBio

E2~Ub conjugates regulate the kinase activity ofShigellaeffector OspG during pathogenesis

(2014) Jonathan N Pruneda et al.   EMBO JOURNAL

Bacterial Serine/Threonine Protein Kinases in Host-Pathogen Interactions

(2014) Marc J. Canova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NleH Defines a New Family of Bacterial Effector Kinases

(2014) Andrey M. Grishin et al.   STRUCTURE

Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG

(2014) Andrey M. Grishin et al.   STRUCTURE

Dimerization-induced allostery in protein kinase regulation

(2014) Hugo Lavoie et al.   TRENDS IN BIOCHEMICAL SCIENCES

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

(2013) James M. Murphy et al.   BIOCHEMICAL JOURNAL

Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments

(2013) Dina Schneidman-Duhovny et al.   BIOPHYSICAL JOURNAL

Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation

(2013) Charlotte Cousin et al.   FEMS MICROBIOLOGY LETTERS

Molecular mimicry and original biochemical strategies for the biogenesis of a Legionella pneumophila replicative niche in phagocytic cells

(2013) Julie Allombert et al.   MICROBES AND INFECTION

The Structural Basis for Control of Eukaryotic Protein Kinases

(2012) Jane A. Endicott et al.   Annual Review of Biochemistry

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation

(2012) Jinsong Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation

(2012) Jon M. Steichen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of the eukaryotic protein kinases as dynamic molecular switches

(2012) S. S. Taylor et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

The Crystal Structure of the Catalytic Domain of the NF-κB Inducing Kinase Reveals a Narrow but Flexible Active Site

(2012) Gladys de Leon-Boenig et al.   STRUCTURE

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

(2011) Maruf M U Ali et al.   EMBO JOURNAL

Protein Kinase LegK2 Is a Type IV Secretion System Effector Involved in Endoplasmic Reticulum Recruitment and Intracellular Replication of Legionella pneumophila

(2011) Eva Hervet et al.   INFECTION AND IMMUNITY

Manipulation of kinase signaling by bacterial pathogens

(2011) Anne Marie Krachler et al.   JOURNAL OF CELL BIOLOGY

Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy

(2011) George T. Lountos et al.   JOURNAL OF STRUCTURAL BIOLOGY

Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF

(2011) J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori proinflammatory protein up-regulates NF- B as a cell-translocating Ser/Thr kinase

(2010) D. J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the conserved internal architecture of a protein kinase

(2009) Alexandr P. Kornev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Combined sampler robot and high-performance liquid chromatography: a fully automated system for biological small-angle X-ray scattering experiments at the Synchrotron SOLEIL SWING beamline

(2009) G. David et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9

(2009) Mark W. Richards et al.   MOLECULAR CELL

A Legionella type IV effector activates the NF- B pathway by phosphorylating the I B family of inhibitors

(2009) J. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

A helix scaffold for the assembly of active protein kinases

(2008) A. P. Kornev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved spatial patterns across the protein kinase family

(2007) Lynn F. Ten Eyck et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS