TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation

Thinking outside of the cell: Secreted protein kinases in bacteria, parasites, and mammals

(2019) Brenden C. Park et al.   IUBMB LIFE

Regulation of Shigella Effector Kinase OspG through Modulation of Its Dynamic Properties

(2018) Andrey M. Grishin et al.   JOURNAL OF MOLECULAR BIOLOGY

The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection

(2018) Pei-Chung Lee et al.   Cell Host & Microbe

MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway

(2017) Amber L. Couzens et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1

(2017) Johannes F. Weijman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control

(2017) Yavuz Kulaberoglu et al.   Nature Communications

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases

(2016) Stephanie Hamill et al.   MOLECULAR CELL

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

(2016) Fuqin Fan et al.   Science Translational Medicine

Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway

(2016) Sun-Yong Kim et al.   Scientific Reports

Structural basis for Mob1-dependent activation of the core Mst–Lats kinase cascade in Hippo signaling

(2015) Lisheng Ni et al.   GENES & DEVELOPMENT

Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host

(2015) Andrey M. Grishin et al.   PROTEIN SCIENCE

Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors

(2015) W. Michael Seganish et al.   ACS Medicinal Chemistry Letters

Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG

(2014) Andrey M. Grishin et al.   STRUCTURE

Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling

(2013) Alexander Hergovich   Cell and Bioscience

Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice

(2012) Miki Nishio et al.   JOURNAL OF CLINICAL INVESTIGATION

Premetazoan Origin of the Hippo Signaling Pathway

(2012) Arnau Sebé-Pedrós et al.   Cell Reports

MOB control: Reviewing a conserved family of kinase regulators

(2011) Alexander Hergovich   CELLULAR SIGNALLING

Prediction of 492 human protein kinase substrate specificities

(2011) Javad Safaei et al.   Proteome Science

Searching protein structure databases with DaliLite v.3

(2008) L. Holm et al.   BIOINFORMATICS

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

(2008) Maria Praskova et al.   CURRENT BIOLOGY

Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1

(2008) S Hirabayashi et al.   ONCOGENE