The bacterial deubiquitinase Ceg23 regulates the association of Lys-63–linked polyubiquitin molecules on the Legionella phagosome

Breaking the chains: deubiquitylating enzyme specificity begets function

(2019) Michael J. Clague et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Post-translational regulation of ubiquitin signaling

(2019) Lei Song et al.   JOURNAL OF CELL BIOLOGY

A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling

(2019) Muyang Wan et al.   Nature Microbiology

LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth

(2018) Tomoko Kubori et al.   CELLULAR MICROBIOLOGY

RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases

(2018) Yi-Han Lin et al.   PLoS Pathogens

Revisiting Bacterial Ubiquitin Ligase Effectors: Weapons for Host Exploitation

(2018) Antonio Pisano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Emerging insights into bacterial deubiquitinases

(2018) Tomoko Kubori et al.   CURRENT OPINION IN MICROBIOLOGY

Legionella and Coxiella effectors: strength in diversity and activity

(2017) Jiazhang Qiu et al.   NATURE REVIEWS MICROBIOLOGY

Hijacking of the Host Ubiquitin Network by Legionella pneumophila

(2017) Jiazhang Qiu et al.   Frontiers in Cellular and Infection Microbiology

Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination

(2016) Sagar Bhogaraju et al.   CELL

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

The ubiquitin system: a critical regulator of innate immunity and pathogen–host interactions

(2016) Jie Li et al.   Cellular & Molecular Immunology

MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

(2016) Syed Arif Abdul Rehman et al.   MOLECULAR CELL

Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

(2016) Jiazhang Qiu et al.   NATURE

The increasing complexity of the ubiquitin code

(2016) Richard Yau et al.   NATURE CELL BIOLOGY

The Salmonella Effector Protein SopA Modulates Innate Immune Responses by Targeting TRIM E3 Ligase Family Members

(2016) Jana Kamanova et al.   PLoS Pathogens

Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination

(2015) Michael J. Sheedlo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploitation of the host ubiquitin system by human bacterial pathogens

(2014) Hiroshi Ashida et al.   NATURE REVIEWS MICROBIOLOGY

The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling

(2014) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

(2014) Maria Stella Ritorto et al.   Nature Communications

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

(2013) Tycho E.T. Mevissen et al.   CELL

The chlamydial OTU domain-containing proteinChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52

(2013) Ana Rita Furtado et al.   CELLULAR MICROBIOLOGY

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

(2013) Reggy Ekkebus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

(2013) A. F. A. Keszei et al.   MOLECULAR AND CELLULAR BIOLOGY

The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity

(2013) Amit P. Bhavsar et al.   PLoS Pathogens

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Generation and physiological roles of linear ubiquitin chains

(2012) Henning Walczak et al.   BMC BIOLOGY

Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation

(2011) Yang Cao et al.   BIOINFORMATICS

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

(2011) Alex C. Faesen et al.   CHEMISTRY & BIOLOGY

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

NleG Type 3 Effectors from Enterohaemorrhagic Escherichia coli Are U-Box E3 Ubiquitin Ligases

(2010) Bin Wu et al.   PLoS Pathogens

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway

(2009) Elsa Lauwers et al.   JOURNAL OF CELL BIOLOGY

DUBs at a glance

(2009) K. D. Wilkinson   JOURNAL OF CELL SCIENCE

Molecular Mimicry by an F-Box Effector of Legionella pneumophila Hijacks a Conserved Polyubiquitination Machinery within Macrophages and Protozoa

(2009) Christopher T. Price et al.   PLoS Pathogens

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Structure of a Shigella effector reveals a new class of ubiquitin ligases

(2008) Yongqun Zhu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

(2008) Alexander U Singer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

(2007) David Komander et al.   BIOCHEMICAL JOURNAL