Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

Brucella abortus Induces a Warburg Shift in Host Metabolism That Is Linked to Enhanced Intracellular Survival of the Pathogen

(2017) Daniel M. Czyż et al.   JOURNAL OF BACTERIOLOGY

Lactate oxidation facilitates growth of Mycobacterium tuberculosis in human macrophages

(2017) Sandra Billig et al.   Scientific Reports

Legionella pneumophila CsrA regulates a metabolic switch from amino acid to glycerolipid metabolism

(2017) Ina Häuslein et al.   Open Biology

Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

(2017) Lindsey Araujo et al.   eLife

To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection

(2017) Wolfgang Eisenreich et al.   Frontiers in Cellular and Infection Microbiology

What Fuels Natural Killers? Metabolism and NK Cell Responses

(2017) Clair M. Gardiner et al.   Frontiers in Immunology

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence againstMycobacterium tuberculosisin human and murine cells

(2016) Ekta Lachmandas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cutting Edge:Mycobacterium tuberculosisInduces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication

(2016) Laura E. Gleeson et al.   JOURNAL OF IMMUNOLOGY

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

(2016) M. Peng et al.   SCIENCE

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

(2016) Ekta Lachmandas et al.   Nature Microbiology

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

A Broken Krebs Cycle in Macrophages

(2015) Luke A.J. O’Neill   IMMUNITY

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

The Cellular and Molecular Basis of Translational Immunometabolism

(2015) Giuseppe Danilo Norata et al.   IMMUNITY

The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ

(2015) Rui Appelberg et al.   IMMUNOLOGY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The metabolic regulation of aging

(2015) Toren Finkel   NATURE MEDICINE

Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy

(2015) Pedro Escoll et al.   NATURE REVIEWS MICROBIOLOGY

Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs

(2015) Lanbo Shi et al.   Scientific Reports

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor

(2015) Esha Madan et al.   Oncotarget

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

The Macrophage Paradox

(2014) Jordan V. Price et al.   IMMUNITY

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tumor Suppressor p53 Alters Host Cell Metabolism to Limit Chlamydia trachomatis Infection

(2014) Christine Siegl et al.   Cell Reports

“Of Mice and Men”: Arginine Metabolism in Macrophages

(2014) Anita C. Thomas et al.   Frontiers in Immunology

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

(2013) A. Michelucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic host responses to infection by intracellular bacterial pathogens

(2013) Wolfgang Eisenreich et al.   Frontiers in Cellular and Infection Microbiology

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells

(2012) B. Everts et al.   BLOOD

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models

(2012) D. C. Lacey et al.   JOURNAL OF IMMUNOLOGY

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells

(2012) Jin Zhang et al.   Nature Protocols

Metabolic Responses of Primary and Transformed Cells to Intracellular Listeria monocytogenes

(2012) Nadine Gillmaier et al.   PLoS One

Developmental stage-specific metabolic and transcriptional activity of Chlamydia trachomatis in an axenic medium

(2012) A. Omsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling in Control of Cell Growth and Metabolism

(2012) P. S. Ward et al.   Cold Spring Harbor Perspectives in Biology

Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

(2012) Pavel Dolezal et al.   PLoS Pathogens

The mitochondrial citrate carrier: a new player in inflammation

(2011) Vittoria Infantino et al.   BIOCHEMICAL JOURNAL

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

Obstacles and opportunities for understanding macrophage polarization

(2011) P. J. Murray et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Metabolic Profiling of Lung Granuloma inMycobacterium tuberculosisInfected Guinea Pigs: Ex vivo1H Magic Angle Spinning NMR Studies

(2011) B. S. Somashekar et al.   JOURNAL OF PROTEOME RESEARCH

1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis

(2011) Ji-Hyun Shin et al.   JOURNAL OF PROTEOME RESEARCH

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Personalized versus evidence-based medicine with PET-based imaging

(2010) Sandip Basu   Nature Reviews Clinical Oncology

Noninvasive Pulmonary [18F]-2-Fluoro-Deoxy-D-Glucose Positron Emission Tomography Correlates with Bactericidal Activity of Tuberculosis Drug Treatment

(2009) S. L. Davis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Acquisition of nutrients by Chlamydiae: unique challenges of living in an intracellular compartment

(2009) Hector Alex Saka et al.   CURRENT OPINION IN MICROBIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY