Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity

Menopause-Related Estrogen Decrease and the Pathogenesis of HFpEF

(2020) Andrea Rodrigues Sabbatini et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling

(2020) Youwen Zhuang et al.   Nature Communications

Dual modulation of formyl peptide receptor 2 by aspirin‐triggered lipoxin contributes to its anti‐inflammatory activity

(2020) Yunjun Ge et al.   FASEB JOURNAL

Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

(2019) Andrew A. House et al.   KIDNEY INTERNATIONAL

Lipoxygenase drives lipidomic and metabolic reprogramming in ischemic heart failure

(2019) Ganesh V. Halade et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

(2019) Burkert Pieske et al.   EUROPEAN HEART JOURNAL

The acute kidney injury to chronic kidney disease transition in a mouse model of acute cardiorenal syndrome emphasizes the role of inflammation

(2019) Katsuyuki Matsushita et al.   KIDNEY INTERNATIONAL

Inhibition of FPR2 impaired leukocytes recruitment and elicited non-resolving inflammation in acute heart failure

(2019) Vasundhara Kain et al.   PHARMACOLOGICAL RESEARCH

Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure

(2019) Bochra Tourki et al.   Molecular Metabolism

Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology

(2018) Ganesh V. Halade et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Characterization of a mouse model of obesity-related fibrotic cardiomyopathy that recapitulates features of human Heart Failure with Preserved Ejection Fraction

(2018) Linda Alex et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation

(2018) Vasundhara Kain et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Macrophages and lipid metabolism

(2018) Anneleen Remmerie et al.   CELLULAR IMMUNOLOGY

Immune responsive resolvin D1 programs myocardial infarction–induced cardiorenal syndrome in heart failure

(2018) Ganesh V. Halade et al.   FASEB JOURNAL

Splenic leukocytes define the resolution of inflammation in heart failure

(2018) Ganesh V. Halade et al.   Science Signaling

Splenic leukocytes define the resolution of inflammation in heart failure

(2018) Ganesh V. Halade et al.   Science Signaling

The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF

(2018) Nazir Savji et al.   JACC-Heart Failure

Obesity-Related Heart Failure With a Preserved Ejection Fraction

(2018) Milton Packer et al.   JACC-Heart Failure

Targeted HFpEF therapy based on matchmaking of human and animal models

(2018) Arantxa Barandiarán Aizpurua et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiorenal Syndrome Revisited

(2018) Faiez Zannad et al.   CIRCULATION

Metabolism Plays a Key Role during Macrophage Activation

(2018) Marion I. Stunault et al.   MEDIATORS OF INFLAMMATION

Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes

(2017) Pietro Enea Lazzerini et al.   HEART

Gain-of-function mutation in SCN5A causes ventricular arrhythmias and early onset atrial fibrillation

(2017) Krystien V. Lieve et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Epidemiology of heart failure with preserved ejection fraction

(2017) Shannon M. Dunlay et al.   Nature Reviews Cardiology

Interaction of endothelial cells with macrophages—linking molecular and metabolic signaling

(2017) Joanna Kalucka et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Heart Failure with Preserved Ejection Fraction in Older Adults

(2017) Bharathi Upadhya et al.   Heart Failure Clinics

Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial Fibrillation

(2017) Ademuyiwa S. Aromolaran et al.   Frontiers in Physiology

Aging, Obesity, and Inflammatory Age-Related Diseases

(2017) Daniela Frasca et al.   Frontiers in Immunology

Targeting Obesity and Diabetes to Treat Heart Failure with Preserved Ejection Fraction

(2017) Raffaele Altara et al.   Frontiers in Endocrinology

Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing

(2017) Vasundhara Kain et al.   Scientific Reports

Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction

(2016) Ganesh V. Halade et al.   Aging-US

Symptom burden in heart failure: assessment, impact on outcomes, and management

(2016) Craig M. Alpert et al.   HEART FAILURE REVIEWS

Chronic Inflammatory Diseases and Endothelial Dysfunction

(2016) Xavier Castellon et al.   Aging and Disease

Altered Myocardial Calcium Cycling and Energetics in Heart Failure—A Rational Approach for Disease Treatment

(2015) Przemek A. Gorski et al.   Cell Metabolism

Association between obesity and glomerular hyperfiltration: the confounding effect of smoking and sodium and protein intakes

(2015) Adam Ogna et al.   EUROPEAN JOURNAL OF NUTRITION

Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function

(2015) Vasundhara Kain et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Patient Selection in Heart Failure With Preserved Ejection Fraction Clinical Trials

(2015) Jacob P. Kelly et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

FPR2/ALXR Agonists and the Resolution of Inflammation

(2014) Olivier Corminboeuf et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Variations in body weight, food intake and body composition after long-term high-fat diet feeding in C57BL/6J mice

(2014) Yongbin Yang et al.   Obesity

Reduced BDNF attenuates inflammation and angiogenesis to improve survival and cardiac function following myocardial infarction in mice

(2013) Ganesh V. Halade et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Immune System as a Sensor of the Metabolic State

(2013) Justin I. Odegaard et al.   IMMUNITY

Obesity, inflammation and the immune system

(2012) Fátima Pérez de Heredia et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Body Mass Index and Adverse Cardiovascular Outcomes in Heart Failure Patients With Preserved Ejection Fraction

(2011) Markus Haass et al.   Circulation-Heart Failure

Obesity Prevalence in the United States — Up, Down, or Sideways?

(2011) Susan Z. Yanovski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dilated Cardiomyopathy With Conduction Disease and Arrhythmia

(2010) Neal K. Lakdawala et al.   CIRCULATION

A Recurring Problem With the Analysis of Energy Expenditure in Genetic Models Expressing Lean and Obese Phenotypes

(2010) A. A. Butler et al.   DIABETES

Electrophysiological remodeling in heart failure

(2010) Yanggan Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac Metabolism and Arrhythmias

(2009) Andreas S. Barth et al.   Circulation-Arrhythmia and Electrophysiology