HMGB1–C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis

HMGB1 enhances AGE-mediated VSMC proliferation via an increase in 5-LO-linked RAGE expression

(2019) Eun Jeong Jang et al.   VASCULAR PHARMACOLOGY

Mediatory roles of leukotriene B4 receptors in LPS-induced endotoxic shock

(2019) Sun-Young Kwon et al.   Scientific Reports

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of non-resolving inflammation in atherosclerosis

(2018) Canan Kasikara et al.   JOURNAL OF CLINICAL INVESTIGATION

Leukotriene biosynthetic enzymes as therapeutic targets

(2018) Jesper Z. Haeggström   JOURNAL OF CLINICAL INVESTIGATION

Association of serum/plasma high mobility group box 1 with autoimmune diseases

(2018) Bin Zhu et al.   MEDICINE

BLTR1 in Monocytes Emerges as a Therapeutic Target For Vascular Inflammation With a Subsequent Intimal Hyperplasia in a Murine Wire-Injured Femoral Artery

(2018) Seung E. Baek et al.   Frontiers in Immunology

LAIR‐1 overexpression and correlation with advanced pathological grade and immune suppressive status in oral squamous cell carcinoma

(2018) Lei‐Lei Yang et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and IRF5 Immune-Mediated Disease Risk Variants Modulate This Outcome

(2018) Matija Hedl et al.   JOURNAL OF IMMUNOLOGY

Role of the Specialized Proresolving Mediator Resolvin D1 in Systemic Lupus Erythematosus: Preliminary Results

(2018) Luca Navarini et al.   Journal of Immunology Research

C1q: A fresh look upon an old molecule

(2017) Nicole M. Thielens et al.   MOLECULAR IMMUNOLOGY

Pro-Resolving Mediators in Regulating and Conferring Macrophage Function

(2017) Jesmond Dalli et al.   Frontiers in Immunology

C1q and HMGB1 reciprocally regulate human macrophage polarization

(2016) M. Son et al.   BLOOD

Modulation of leukotriene B4 receptor 1 signaling by receptor for advanced glycation end products (RAGE)

(2016) Takako Ichiki et al.   FASEB JOURNAL

Resolvin D1, resolvin D2 and maresin 1 activate the GSK3β anti-inflammatory axis in TLR4-engaged human monocytes

(2016) Zhen Gu et al.   Innate Immunity

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

(2016) Jesmond Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon regulatory factor 5 in human autoimmunity and murine models of autoimmune disease

(2016) Hayley L. Eames et al.   Translational Research

Clinical significance of leukocyte-associated immunoglobulin-like receptor-1 expression in human cervical cancer

(2016) Yue Wang et al.   Experimental and Therapeutic Medicine

C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

(2016) Roberta Bulla et al.   Nature Communications

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

(2016) Gabrielle Fredman et al.   Nature Communications

IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation

(2016) Matija Hedl et al.   Cell Reports

Fundamental role of C1q in autoimmunity and inflammation

(2015) Myoungsun Son et al.   IMMUNOLOGIC RESEARCH

IRF5 Deficiency Ameliorates Lupus but Promotes Atherosclerosis and Metabolic Dysfunction in a Mouse Model of Lupus-Associated Atherosclerosis

(2015) Amanda A. Watkins et al.   JOURNAL OF IMMUNOLOGY

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

(2015) Elise Dalmas et al.   NATURE MEDICINE

Diagnosis, Monitoring, and Treatment of Systemic Lupus Erythematosus: A Systematic Review of Clinical Practice Guidelines

(2015) David J. Tunnicliffe et al.   ARTHRITIS CARE & RESEARCH

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins

(2014) Weston Spivia et al.   INFLAMMATION RESEARCH

Type I Interferon in the Pathogenesis of Lupus

(2014) M. K. Crow   JOURNAL OF IMMUNOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Interferon Regulatory Factor-5 Deficiency Ameliorates Disease Severity in the MRL/lpr Mouse Model of Lupus in the Absence of a Mutation in DOCK2

(2014) Kei Yasuda et al.   PLoS One

Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4synthesis by inhibiting a calcium-activated kinase pathway

(2014) Gabrielle Fredman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Advances in the Search for Novel 5-Lipoxygenase Inhibitors

(2013) Dieter Steinhilber et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

(2013) Matthew Spite et al.   Cell Metabolism

Leukotriene B4 receptor BLT2 negatively regulates allergic airway eosinophilia

(2013) Yuko Matsunaga et al.   FASEB JOURNAL

D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury

(2013) Takuya Miyahara et al.   FASEB JOURNAL

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

(2013) Cherilyn M. Sirois et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Irf5-deficient mice are protected from pristane-induced lupus via increased Th2 cytokines and altered IgG class switching

(2012) Di Feng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C1q limits dendritic cell differentiation and activation by engaging LAIR-1

(2012) M. Son et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

(2011) Rivka C. Stone et al.   ARTHRITIS AND RHEUMATISM

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

(2011) Esther Titos et al.   JOURNAL OF IMMUNOLOGY

Lipoxins as biomarkers of lupus and other inflammatory conditions

(2011) Undurti N Das   Lipids in Health and Disease

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation

(2010) Charles N. Serhan   AMERICAN JOURNAL OF PATHOLOGY

Leukotrienes and Atherosclerosis

(2010) Graziano Riccioni et al.   CURRENT DRUG TARGETS

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Phosphorylation of Serine 271 on 5-Lipoxygenase and Its Role in Nuclear Export

(2008) Nicolas Flamand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY