Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages

Krebs Cycle Reborn in Macrophage Immunometabolism

(2020) Dylan G. Ryan et al.   Annual Review of Immunology

Pharmacological targets of metabolism in disease: Opportunities from macrophages

(2020) Alessandra Castegna et al.   PHARMACOLOGY & THERAPEUTICS

Functional Annotation of the Transcriptome of the Pig, Sus scrofa, Based Upon Network Analysis of an RNAseq Transcriptional Atlas

(2020) Kim M. Summers et al.   Frontiers in Genetics

Establishment and Maintenance of the Macrophage Niche

(2020) Martin Guilliams et al.   IMMUNITY

Understanding the mechanisms that facilitate specificity, not redundancy, of chemokine‐mediated leukocyte recruitment

(2020) Douglas P. Dyer   IMMUNOLOGY

cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation

(2020) Hayley I. Muendlein et al.   SCIENCE

Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166

(2020) Henri-François Renard et al.   Nature Communications

ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function

(2019) Nelli Baal et al.   JOURNAL OF IMMUNOLOGY

Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1

(2019) Alex J. Freemerman et al.   JOURNAL OF IMMUNOLOGY

ENPP1 in the Regulation of Mineralization and Beyond

(2019) Fiona Roberts et al.   TRENDS IN BIOCHEMICAL SCIENCES

Characterization of Glucose Transporter 6 in Lipopolysaccharide-Induced Bone Marrow–Derived Macrophage Function

(2019) Beth T. Caruana et al.   JOURNAL OF IMMUNOLOGY

Phenotypic impacts of CSF1R deficiencies in humans and model organisms

(2019) David A. Hume et al.   JOURNAL OF LEUKOCYTE BIOLOGY

STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation

(2019) Saroj Nepal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus

(2019) Christopher A. Odhams et al.   Nature Communications

Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21

(2019) Valerie M. Harris et al.   Frontiers in Immunology

A Gene Expression Atlas of the Domestic Water Buffalo (Bubalus bubalis)

(2019) Rachel Young et al.   Frontiers in Genetics

Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

(2019) Larisa I Labzin et al.   EMBO JOURNAL

Free Fatty Acid Receptors in Health and Disease

(2019) Ikuo Kimura et al.   PHYSIOLOGICAL REVIEWS

Mice deficient in NKLAM have attenuated inflammatory cytokine production in a Sendai virus pneumonia model

(2019) Donald W. Lawrence et al.   PLoS One

A Mini-Atlas of Gene Expression for the Domestic Goat (Capra hircus)

(2019) Charity Muriuki et al.   Frontiers in Genetics

Analysis of the Progeny of Sibling Matings Reveals Regulatory Variation Impacting the Transcriptome of Immune Cells in Commercial Chickens

(2019) Lucy Freem et al.   Frontiers in Genetics

A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells

(2019) Hee Chan Yoo et al.   Cell Metabolism

TRIM21 controls Toll‐like receptor 2 responses in bone‐marrow‐derived macrophages

(2019) Maria Sjöstrand et al.   IMMUNOLOGY

Regulation of inflammatory gene expression in macrophages by epithelial-stromal interaction 1 (Epsti1)

(2018) Young-Hoon Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function

(2018) Verena M. Link et al.   CELL

The Human Transcription Factors

(2018) Samuel A. Lambert et al.   CELL

Neutrophil chemotaxis

(2018) Björn Petri et al.   CELL AND TISSUE RESEARCH

The multiple functions and mechanisms of osteopontin

(2018) Mehmet Arif Icer et al.   CLINICAL BIOCHEMISTRY

IL1β and TNFα promote RANKL-dependent adseverin expression and osteoclastogenesis

(2018) Yongqiang Wang et al.   JOURNAL OF CELL SCIENCE

Arginase: A Multifaceted Enzyme Important in Health and Disease

(2018) R. William Caldwell et al.   PHYSIOLOGICAL REVIEWS

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer

(2018) Cecilia Garlanda et al.   PHYSIOLOGICAL REVIEWS

Single cell analysis of kynurenine and System L amino acid transport in T cells

(2018) Linda V. Sinclair et al.   Nature Communications

A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

(2018) Gayatri Subramanian et al.   PLoS Pathogens

Downregulation of SLC7A7 Triggers an Inflammatory Phenotype in Human Macrophages and Airway Epithelial Cells

(2018) Bianca Maria Rotoli et al.   Frontiers in Immunology

S100 Proteins As an Important Regulator of Macrophage Inflammation

(2018) Chang Xia et al.   Frontiers in Immunology

Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken

(2018) Stephen J. Bush et al.   BMC GENOMICS

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

The Mononuclear Phagocyte System: The Relationship between Monocytes and Macrophages

(2018) David A. Hume et al.   TRENDS IN IMMUNOLOGY

ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages

(2018) Lindsey A. Waddell et al.   Frontiers in Immunology

Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned

(2017) Matthew T Drake et al.   ENDOCRINE REVIEWS

Foundations of Immunometabolism and Implications for Metabolic Health and Disease

(2017) Gökhan S. Hotamisligil   IMMUNITY

The functions and unique features of long intergenic non-coding RNA

(2017) Julia D. Ransohoff et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival

(2017) Konrad Buscher et al.   Nature Communications

Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4

(2017) Nina Van Opdenbosch et al.   Cell Reports

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

(2017) Erika M. Palmieri et al.   Cell Reports

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease

(2017) J. Kenneth Baillie et al.   PLoS Genetics

A high resolution atlas of gene expression in the domestic sheep (Ovis aries)

(2017) Emily L. Clark et al.   PLoS Genetics

TRIM23 mediates virus-induced autophagy via activation of TBK1

(2017) Konstantin M. J. Sparrer et al.   Nature Microbiology

Complexity and conservation of regulatory landscapes underlie evolutionary resilience of mammalian gene expression

(2017) Camille Berthelot et al.   Nature Ecology & Evolution

Glutamine transporters in mammalian cells and their functions in physiology and cancer

(2016) Yangzom D. Bhutia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Comparative transcriptome analysis of equine alveolar macrophages

(2016) A.E. Karagianni et al.   EQUINE VETERINARY JOURNAL

Glucose transporter expression differs between bovine monocyte and macrophage subsets and is influenced by milk production

(2016) M. Eger et al.   JOURNAL OF DAIRY SCIENCE

PFKFB3-Driven Macrophage Glycolytic Metabolism Is a Crucial Component of Innate Antiviral Defense

(2016) Hui Jiang et al.   JOURNAL OF IMMUNOLOGY

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury

(2016) Manish Mittal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C9orf72 is required for proper macrophage and microglial function in mice

(2016) J. G. ORourke et al.   SCIENCE

RNA editing generates cellular subsets with diverse sequence within populations

(2016) Dewi Harjanto et al.   Nature Communications

Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor

(2016) Abigail S. Krall et al.   Nature Communications

Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation

(2016) Amy R. Johnson et al.   Molecular Metabolism

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production

(2015) Md Jamal Uddin et al.   Cellular & Molecular Immunology

The biology of interleukin-27 reveals unique pro- and anti-inflammatory functions in immunity

(2015) Samadhi Aparicio-Siegmund et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Mouse and human FcR effector functions

(2015) Pierre Bruhns et al.   IMMUNOLOGICAL REVIEWS

Enhancer Turnover Is Associated with a Divergent Transcriptional Response to Glucocorticoid in Mouse and Human Macrophages

(2015) Alasdair W. Jubb et al.   JOURNAL OF IMMUNOLOGY

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

(2015) Yong Zhang et al.   NATURE IMMUNOLOGY

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

(2015) Shraddha Sharma et al.   Nature Communications

The Many Alternative Faces of Macrophage Activation

(2015) David A. Hume   Frontiers in Immunology

The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells

(2014) W. K. Chan et al.   BLOOD

Transcription and enhancer profiling in human monocyte subsets

(2014) C. Schmidl et al.   BLOOD

Akirin2 is critical for inducing inflammatory genes by bridging I B-  and the SWI/SNF complex

(2014) S. Tartey et al.   EMBO JOURNAL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Human macrophage polarization in vitro: Maturation and activation methods compared

(2014) Daphne Y.S. Vogel et al.   IMMUNOBIOLOGY

Transcriptomic analysis of mononuclear phagocyte differentiation and activation

(2014) David A. Hume et al.   IMMUNOLOGICAL REVIEWS

The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages

(2014) Zheng Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators

(2014) S. Raza et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

(2014) B. P. Fairfax et al.   SCIENCE

CSF-1 Receptor Signaling in Myeloid Cells

(2014) E. R. Stanley et al.   Cold Spring Harbor Perspectives in Biology

The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation

(2014) M S Rodriguez et al.   Cell Death & Disease

The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide

(2013) Ronan Kapetanovic et al.   BMC GENOMICS

Role of Macrophage Receptor with Collagenous Structure in Innate Immune Tolerance

(2013) J. Jing et al.   JOURNAL OF IMMUNOLOGY

Modulation of inflammation by interleukin-27

(2013) Markus Bosmann et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription

(2013) Minna U. Kaikkonen et al.   MOLECULAR CELL

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

The mammalian PYHIN gene family: Phylogeny, evolution and expression

(2012) Jasmyn A Cridland et al.   BMC EVOLUTIONARY BIOLOGY

Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1

(2012) Joseph E. Qualls et al.   Cell Host & Microbe

E3 ubiquitin ligase NKLAM is a macrophage phagosome protein and plays a role in bacterial killing

(2012) Donald W. Lawrence et al.   CELLULAR IMMUNOLOGY

Pig Bone Marrow-Derived Macrophages Resemble Human Macrophages in Their Response to Bacterial Lipopolysaccharide

(2012) R. Kapetanovic et al.   JOURNAL OF IMMUNOLOGY

Inflammasome-Activated Caspase 7 Cleaves PARP1 to Enhance the Expression of a Subset of NF-κB Target Genes

(2012) Süheda Erener et al.   MOLECULAR CELL

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(2012) K. Schroder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting negative regulation of Toll-like receptor signaling

(2012) Takeshi Kondo et al.   TRENDS IN IMMUNOLOGY

Ensembl BioMarts: a hub for data retrieval across taxonomic space

(2011) R. J. Kinsella et al.   Database-The Journal of Biological Databases and Curation

PNPASE Regulates RNA Import into Mitochondria

(2010) Geng Wang et al.   CELL

Functional clustering and lineage markers: Insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations

(2010) David A. Hume et al.   GENOMICS

The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A

(2009) Shao-Chun Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pregnancy, indoleamine 2,3-dioxygenase (IDO) and chlamydial abortion: An unresolved paradox

(2008) Gary Entrican et al.   VETERINARY MICROBIOLOGY