Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

Published 2017 View Full Article

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Title
Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
Authors
Keywords
glutamine, glutamine synthetase, macrophages, succinate, HIF1α, metastasis, IL-10, starvation, metabolic rewiring
Journal
Cell Reports
Volume 20, Issue 7, Pages 1654-1666
Publisher
Elsevier BV
Online
2017-08-16
DOI
10.1016/j.celrep.2017.07.054

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