TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury

The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions

(2016) Douglas P. Dyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation, fibrosis, and modulation of the process by mesenchymal stem/stromal cells

(2016) Darwin J. Prockop   MATRIX BIOLOGY

Novel Role of Reactive Oxygen Species–ActivatedtrpMelastatin Channel-2 in Mediating Angiogenesis and Postischemic NeovascularizationSignificance

(2015) Manish Mittal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The development and function of lung-resident macrophages and dendritic cells

(2015) Manfred Kopf et al.   NATURE IMMUNOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Cooperative Signaling via Transcription Factors NF-κB and AP1/c-Fos Mediates Endothelial Cell STIM1 Expression and Hyperpermeability in Response to Endotoxin

(2014) Auditi DebRoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo

(2014) Ryang Hwa Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice

(2014) Yuki Takaoka et al.   Scientific Reports

Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungs

(2013) Andrea M. Foskett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation and Repair of the Alveolar-Capillary Barrier in Acute Lung Injury

(2013) Jahar Bhattacharya et al.   Annual Review of Physiology

TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity

(2013) D. J. Kota et al.   DIABETES

Identification of the HSPB4/TLR2/NF-κB axis in macrophage as a therapeutic target for sterile inflammation of the cornea

(2012) Joo Youn Oh et al.   EMBO Molecular Medicine

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

(2011) Darwin J Prockop et al.   MOLECULAR THERAPY

Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6

(2011) Svitlana Danchuk et al.   Stem Cell Research & Therapy

Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury

(2010) J. Y. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE