Selectins—The Two Dr. Jekyll and Mr. Hyde Faces of Adhesion Molecules—A Review
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Title
Selectins—The Two Dr. Jekyll and Mr. Hyde Faces of Adhesion Molecules—A Review
Authors
Keywords
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Journal
MOLECULES
Volume 25, Issue 12, Pages 2835
Publisher
MDPI AG
Online
2020-06-20
DOI
10.3390/molecules25122835
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Note: Only part of the references are listed.- Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms
- (2019) Geert van Weelden et al. Marine Drugs
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- (2019) Zhishuai Ye et al. MEDIATORS OF INFLAMMATION
- PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions
- (2019) Xiaona Huang et al. Protein & Cell
- Design and synthesis of glycomimetics: Recent advances
- (2019) Alice Tamburrini et al. MEDICINAL RESEARCH REVIEWS
- Cell Adhesion Molecules and Their Roles and Regulation in the Immune and Tumor Microenvironment
- (2019) Heidi Harjunpää et al. Frontiers in Immunology
- Altered Cell Adhesion and Glycosylation Promote Cancer Immune Suppression and Metastasis
- (2019) Heinz Läubli et al. Frontiers in Immunology
- Cancer glycan epitopes: biosynthesis, structure and function
- (2018) Oliver M T Pearce GLYCOBIOLOGY
- E-Selectin Ligands in the Human Mononuclear Phagocyte System: Implications for Infection, Inflammation, and Immunotherapy
- (2018) Mariana Silva et al. Frontiers in Immunology
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- (2018) Torben Heise et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sialylation is involved in cell fate decision during development, reprogramming and cancer progression
- (2018) Fenjie Li et al. Protein & Cell
- Selectins in cancer immunity
- (2017) Lubor Borsig GLYCOBIOLOGY
- Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
- (2017) Mariana Silva et al. JOURNAL OF IMMUNOLOGY
- Transition State-Based Sialyltransferase Inhibitors: Mimicking Oxocarbenium Ion by Simple Amide
- (2017) Jian Guo et al. JOURNAL OF MEDICINAL CHEMISTRY
- PSGL-1: A New Player in the Immune Checkpoint Landscape
- (2017) Roberto Tinoco et al. TRENDS IN IMMUNOLOGY
- P-, but not E- or L-, selectin-mediated rolling adhesion persistence in hemodynamic flow diverges between metastatic and leukocytic cells
- (2017) Erin Elizabeth Edwards et al. Oncotarget
- Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration
- (2016) Kai E. Moog et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Sialyltransferase inhibition and recent advances
- (2016) Libo Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Binding free energy calculations on E-selectin complexes with sLex oligosaccharide analogs
- (2016) Pabla A. Barra et al. Chemical Biology & Drug Design
- Uncharged nucleoside inhibitors of β-1,4-galactosyltransferase with activity in cells
- (2016) Jingqian Jiang et al. CHEMICAL COMMUNICATIONS
- Discovery of New E-Selectin Inhibitors by Virtual Screening, Fluorescence Binding Assays, and STD NMR Experiments
- (2016) Pabla A. Barra et al. ChemMedChem
- Aceclofenac: Species-Dependent Metabolism and Newer Paradigm Shift from Oral to Non-oral Delivery
- (2016) Gajanand Sharma et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Biological roles of glycans
- (2016) Ajit Varki GLYCOBIOLOGY
- Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force
- (2016) Padmaja Mehta-D'souza et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Different QM/MM Approaches To Elucidate Enzymatic Reactions: Case Study on ppGalNAcT2
- (2016) Pavel Janoš et al. Journal of Chemical Theory and Computation
- Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and Opportunities
- (2016) Rémi Szabo et al. MEDICINAL RESEARCH REVIEWS
- P-selectin is a nanotherapeutic delivery target in the tumor microenvironment
- (2016) Y. Shamay et al. Science Translational Medicine
- Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone
- (2016) Trevor T. Price et al. Science Translational Medicine
- Targeting Selectins and Their Ligands in Cancer
- (2016) Alessandro Natoni et al. Frontiers in Oncology
- Turning-Off Signaling by Siglecs, Selectins, and Galectins: Chemical Inhibition of Glycan-Dependent Interactions in Cancer
- (2016) Alejandro J. Cagnoni et al. Frontiers in Oncology
- Transition States and Transition State Analogue Interactions with Enzymes
- (2015) Vern L. Schramm ACCOUNTS OF CHEMICAL RESEARCH
- Transition state theory for enzyme kinetics
- (2015) Donald G. Truhlar ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Computational Evidence for the Catalytic Mechanism of Tyrosylprotein Sulfotransferases: A Density Functional Theory Investigation
- (2015) Tainah Dorina Marforio et al. BIOCHEMISTRY
- Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use
- (2015) M. J. Telen et al. BLOOD
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- (2015) Igor Tvaroška CARBOHYDRATE RESEARCH
- Selectins: initiators of leucocyte adhesion and signalling at the vascular wall
- (2015) Rodger P. McEver CARDIOVASCULAR RESEARCH
- Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential
- (2015) Farzaneh Atashrazm et al. Marine Drugs
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- (2015) Reza Abdi et al. STEM CELLS
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- (2015) Roland C. Preston et al. Journal of Molecular Cell Biology
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- (2015) Tomáš Trnka et al. PLoS Computational Biology
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- (2014) Dibyendu Samanta et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2014) Samy Cecioni et al. CHEMICAL REVIEWS
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- (2014) Matthew S. Macauley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fucoidan as a Marine Anticancer Agent in Preclinical Development
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- (2012) Florian P. C. Binder et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2012) Pedro Merino et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome
- (2012) Cory D Rillahan et al. Nature Chemical Biology
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- (2012) Mickael Calosso et al. ACS Medicinal Chemistry Letters
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- (2012) M. Labelle et al. Cancer Discovery
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- (2012) Craig T. Lefort et al. Frontiers in Immunology
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- (2011) Yue Geng et al. ANNALS OF BIOMEDICAL ENGINEERING
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- (2011) Robert Sackstein ANNALS OF BIOMEDICAL ENGINEERING
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- (2011) J. S. Merzaban et al. BLOOD
- Pre-organization of the Core Structure of E-Selectin Antagonists
- (2011) Daniel Schwizer et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2011) Catherine A. et al. Frontiers in Bioscience-Landmark
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- (2011) E. O. KOZLOWSKI et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
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- (2011) Sachie Hiratsuka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bases moleculares de las interacciones leucocito-endotelio durante la respuesta inflamatoria
- (2011) Olga Barreiro et al. REVISTA ESPANOLA DE CARDIOLOGIA
- Rolling Cell Adhesion
- (2010) Rodger P. McEver et al. Annual Review of Cell and Developmental Biology
- The Synergy of 6-O-Sulfation andN- or 3-O-Sulfation of Chitosan Is Required for Efficient Inhibition of P-Selectin-Mediated Human Melanoma A375 Cell Adhesion
- (2010) Ruifei WANG et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils
- (2010) Y. Kuwano et al. BLOOD
- Thermodynamics and chemical characterization of protein–carbohydrate interactions: The multivalency issue
- (2010) Michael Reynolds et al. COMPTES RENDUS CHIMIE
- Selectin inhibitors: a patent review
- (2010) Patricia W Bedard et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Current trends in the structure-activity relationships of sialyltransferases
- (2010) M. Audry et al. GLYCOBIOLOGY
- A novel sialyltransferase inhibitor AL10 suppresses invasion and metastasis of lung cancer cells by inhibiting integrin-mediated signaling
- (2010) Chi-Hsiang Chiang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- An Efficient Approach to the Discovery of Potent Inhibitors against Glycosyltransferases
- (2010) Kensaku Hosoguchi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural and mechanistic basis for a new mode of glycosyltransferase inhibition
- (2010) Thomas Pesnot et al. Nature Chemical Biology
- Selectins promote tumor metastasis
- (2010) Heinz Läubli et al. SEMINARS IN CANCER BIOLOGY
- Cancer Cells in Transit: The Vascular Interactions of Tumor Cells
- (2009) Konstantinos Konstantopoulos et al. Annual Review of Biomedical Engineering
- Glycoforms of human endothelial CD34 that bind L-selectin carry sulfated sialyl Lewis x capped O- and N-glycans
- (2009) G. H. Mir et al. BLOOD
- Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes
- (2009) H. Laubli et al. BLOOD
- Bisubstrate Analogues as Glycosyltransferase Inhibitors
- (2009) Masayuki Izumi et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migration
- (2009) Robert Sackstein IMMUNOLOGICAL REVIEWS
- Glycosylation in immune cell trafficking
- (2009) Markus Sperandio et al. IMMUNOLOGICAL REVIEWS
- Lymphocytes in the Peritoneum Home to the Omentum and Are Activated by Resident Dendritic Cells
- (2009) D. A. Carlow et al. JOURNAL OF IMMUNOLOGY
- Atomistic Simulation Combined with Analytic Theory To Study the Response of the P-Selectin/PSGL-1 Complex to an External Force
- (2009) Kim N. Gunnerson et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Hybrid Quantum Mechanical/Molecular Mechanical Investigation of the β-1,4-Galactosyltransferase-I Mechanism
- (2009) Martin Krupička et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Enzymatic transition states and dynamic motion in barrier crossing
- (2009) Steven D Schwartz et al. Nature Chemical Biology
- From carbohydrate leads to glycomimetic drugs
- (2009) Beat Ernst et al. NATURE REVIEWS DRUG DISCOVERY
- Structural insight into mammalian sialyltransferases
- (2009) Francesco V Rao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transmission of allostery through the lectin domain in selectin-mediated cell adhesion
- (2009) T. T. Waldron et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for selectin mechanochemistry
- (2009) T. A. Springer PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo
- (2009) Christian Ostrau et al. RADIOTHERAPY AND ONCOLOGY
- Synthesis of Glycosyltransferase Inhibitors
- (2009) Tetsuya Kajimoto et al. SYNTHESIS-STUTTGART
- Mechanisms for Flow-Enhanced Cell Adhesion
- (2008) Cheng Zhu et al. ANNALS OF BIOMEDICAL ENGINEERING
- Catch Bonds in Adhesion
- (2008) Wendy Thomas Annual Review of Biomedical Engineering
- Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets
- (2008) Laure Bachelet et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- The selectin–selectin ligand axis in tumor progression
- (2008) Isaac P. Witz CANCER AND METASTASIS REVIEWS
- DFT and Docking Study of Potential Transition State Analogue Inhibitors of Glycosyltransferases
- (2008) Lucie Sihelniková et al. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
- Replacing a Lectin Domain Residue in L-selectin Enhances Binding to P-selectin Glycoprotein Ligand-1 but Not to 6-Sulfo-sialyl Lewis x
- (2008) Arkadiusz G. Klopocki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deoxygenated Disaccharide Analogs as Specific Inhibitors of β1–4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis
- (2008) Jillian R. Brown et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel functions of the CD34 family
- (2008) J. S. Nielsen et al. JOURNAL OF CELL SCIENCE
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
- Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone
- (2008) Robert Sackstein et al. NATURE MEDICINE
- The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics
- (2008) B. L. Cantarel et al. NUCLEIC ACIDS RESEARCH
- Novel derivatives of UDP-glucose: concise synthesis and fluorescent properties
- (2008) Thomas Pesnot et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- CD44v4 Is a Major E-Selectin Ligand that Mediates Breast Cancer Cell Transendothelial Migration
- (2008) Ke Zen et al. PLoS One
- Two-directional total synthesis of efomycine M and formal total synthesis of elaiolide
- (2008) Roland Barth et al. TETRAHEDRON
- Glycosyltransferases: Structures, Functions, and Mechanisms
- (2007) L.L. Lairson et al. Annual Review of Biochemistry
- Monitoring Receptor-Ligand Interactions between Surfaces by Thermal Fluctuations
- (2007) Wei Chen et al. BIOPHYSICAL JOURNAL
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