Multivalency as a Chemical Organization and Action Principle

Quantifying the rebinding effect in multivalent chemical ligand-receptor systems

(2012) Marcus Weber et al.   JOURNAL OF CHEMICAL PHYSICS

Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds

(2012) Ethan A. Englund et al.   Nature Communications

DNA-Controlled Bivalent Presentation of Ligands for the Estrogen Receptor

(2011) Frank Abendroth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

All-or-Nothing Cooperative Self-Assembly of an Annulene Sandwich

(2011) Johannes K. Sprafke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Allosteric, Chelate, and Interannular Cooperativity: A Mise au Point

(2011) Gianfranco Ercolani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA as a Molecular Ruler: Interrogation of a Tandem SH2 Domain with Self-Assembled, Bivalent DNA-Peptide Complexes

(2011) Hendrik Eberhard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of Multivalent Carbohydrate-Protein Interactions Studied by EPR Spectroscopy

(2011) Patrick Braun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescence Imaging with Multifunctional Polyglycerol Sulfates: Novel Polymeric near-IR Probes Targeting Inflammation

(2011) Kai Licha et al.   BIOCONJUGATE CHEMISTRY

Conformational Analysis of Bivalent Estrogen Receptor Ligands: From Intramolecular to Intermolecular Binding

(2011) Min Shan et al.   CHEMBIOCHEM

Inhibition of Influenza Virus Activity by Multivalent Glycoarchitectures with Matched Sizes

(2011) Ilona Papp et al.   CHEMBIOCHEM

Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds

(2011) Lukas M. Artner et al.   CHEMICAL COMMUNICATIONS

DNA-guided display of proteins and protein ligands for the interrogation of biology

(2011) Franziska Diezmann et al.   CHEMICAL SOCIETY REVIEWS

Towards a rational spacer design for bivalent inhibition of estrogen receptor

(2011) Alexander Bujotzek et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Relationship Between Conformational Flexibility and Chelate Cooperativity

(2011) M. Cristina Misuraca et al.   JOURNAL OF ORGANIC CHEMISTRY

Stepwise Effective Molarities in Porphyrin Oligomer Complexes: Preorganization Results in Exceptionally Strong Chelate Cooperativity

(2011) Hannah J. Hogben et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing Multivalent Interactions in a Synthetic Host–Guest Complex by Dynamic Force Spectroscopy

(2011) Alberto Gomez-Casado et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Using Covalent Dimers of Human Carbonic Anhydrase II To Model Bivalency in Immunoglobulins

(2011) Eric T. Mack et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chelate Cooperativity and Spacer Length Effects on the Assembly Thermodynamics and Kinetics of Divalent Pseudorotaxanes

(2011) Wei Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Role of Dimension in Multivalent Binding Events: Structure-Activity Relationship of Dendritic Polyglycerol Sulfate Binding to L-Selectin in Correlation with Size and Surface Charge Density

(2011) Marie Weinhart et al.   MACROMOLECULAR BIOSCIENCE

Gradient-driven motion of multivalent ligand molecules along a surface functionalized with multiple receptors

(2011) András Perl et al.   Nature Chemistry

Multivalent interaction and selectivities in selectin binding of functionalized gold colloids decorated with carbohydrate mimetics

(2011) Meike Roskamp et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

DNA-programmed spatial screening of carbohydrate–lectin interactions

(2011) Christian Scheibe et al.   Chemical Science

DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles

(2011) Jean Pierre Daguer et al.   Chemical Science

Solvent effects on chelate cooperativity

(2011) Christopher A. Hunter et al.   Chemical Science

Chemically Directed Immobilization of Nanoparticles onto Gold Substrates for Orthogonal Assembly Using Dithiocarbamate Bond Formation

(2010) Myoung-Hwan Park et al.   ACS Applied Materials & Interfaces

Synthesis, Reductive Cleavage, and Cellular Interaction Studies of Biodegradable, Polyglycerol Nanogels

(2010) Dirk Steinhilber et al.   ADVANCED FUNCTIONAL MATERIALS

A Synthetic “Tour de Force”: Well-Defined Multivalent and Multimodal Dendritic Structures for Biomedical Applications

(2010) Lars Röglin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Surface Chemistry of Metal-Organic Frameworks at the Liquid-Solid Interface

(2010) Denise Zacher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Carbohydrate-Functionalized Quantum Dots in Microreactors

(2010) Raghavendra Kikkeri et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semisynthetic DNA-Protein Conjugates for Biosensing and Nanofabrication

(2010) Christof M. Niemeyer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Clustered “Patchy” Nanoparticles for Modulated Cellular Uptake and In Vivo Tumor Targeting

(2010) Zhiyong Poon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Drug-Free Macromolecular Therapeutics: Induction of Apoptosis by Coiled-Coil-Mediated Cross-Linking of Antigens on the Cell Surface

(2010) Kuangshi Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanomaterials Based on DNA

(2010) Nadrian C. Seeman   Annual Review of Biochemistry

GABACReceptor Binding of Quantum-Dot Conjugates of Variable Ligand Valency

(2010) Hélène A. Gussin et al.   BIOCONJUGATE CHEMISTRY

Dendritic Polyglycerols with Oligoamine Shells Show Low Toxicity and High siRNA Transfection Efficiency in Vitro

(2010) Wiebke Fischer et al.   BIOCONJUGATE CHEMISTRY

Isolation of Potent and Specific Trypsin Inhibitors from a DNA-Encoded Chemical Library

(2010) Luca Mannocci et al.   BIOCONJUGATE CHEMISTRY

Multiple glycosylation of de novo designed α-helical coiled coil peptides

(2010) Jessica A. Falenski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ligand dimerization programmed by hybridization to study multimeric ligand–receptor interactions

(2010) Katarzyna Gorska et al.   CHEMICAL COMMUNICATIONS

Sugar-Decorated Sugar Vesicles: Lectin-Carbohydrate Recognition at the Surface of Cyclodextrin Vesicles

(2010) Jens Voskuhl et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly monodisperse water-dispersable iron oxide nanoparticles for biomedical applications

(2010) Andreas Hofmann et al.   JOURNAL OF MATERIALS CHEMISTRY

Structural Basis of Multivalent Binding to Wheat Germ Agglutinin

(2010) David Schwefel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dissection of Complex Molecular Recognition Interfaces

(2010) Christopher A. Hunter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Immobilization and Molecular Interactions between Bacteriophage and Lipopolysaccharide Bilayers

(2010) Hitesh Handa et al.   LANGMUIR

Structural DNA Nanotechnology: Growing Along withNano Letters

(2010) Nadrian C. Seeman   NANO LETTERS

Synthesis of glycopolymers and their multivalent recognitions with lectins

(2010) S. R. Simon Ting et al.   Polymer Chemistry

Dendritic polyglycerol sulfates as multivalent inhibitors of inflammation

(2010) J. Dernedde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide

(2010) Ethan A. Merritt et al.   PROTEIN SCIENCE

Hybrid strategies in nanolithography

(2010) Héctor M Saavedra et al.   REPORTS ON PROGRESS IN PHYSICS

Inhibition of Influenza Virus Infection by Multivalent Sialic-Acid-Functionalized Gold Nanoparticles

(2010) Ilona Papp et al.   Small

ssDNA templated assembly of oligonucleotides and bivalent naphthalene guests

(2010) Pim G. A. Janssen et al.   Soft Matter

A comparison of mono and multivalent linkers and their effect on the colloidal stability of nanoparticle and immunoassays performance

(2010) Vladimir Gubala et al.   TALANTA

Fabrication and Luminescence of Designer Surface Patterns with β-Cyclodextrin Functionalized Quantum Dots via Multivalent Supramolecular Coupling

(2009) Denis Dorokhin et al.   ACS Nano

Synthesis of Fluorescent Carbohydrate-Protected Au Nanodots for Detection of Concanavalin A andEscherichia coli

(2009) Chih-Ching Huang et al.   ANALYTICAL CHEMISTRY

Biocompatible Functionalized Polyglycerol Microgels with Cell Penetrating Properties

(2009) Adam L. Sisson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

(2009) Katarzyna Gorska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binding Mechanisms in Supramolecular Complexes

(2009) Hans-Jörg Schneider   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

What is Cooperativity?

(2009) Christopher A. Hunter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold Nanoparticle Arrangement on Viral Particles through Carbohydrate Recognition: A Non-Cross-Linking Approach to Optical Virus Detection

(2009) Kenichi Niikura et al.   BIOCONJUGATE CHEMISTRY

Inhibition of selectin binding by colloidal gold with functionalized shells

(2009) Jens Dernedde et al.   CHEMICAL COMMUNICATIONS

Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions

(2009) Narayanaswamy Jayaraman   CHEMICAL SOCIETY REVIEWS

Nucleic acid-guided assembly of aromatic chromophores

(2009) Vladimir L. Malinovskii et al.   CHEMICAL SOCIETY REVIEWS

Multivalency in the Assembly of Intrinsically Disordered Dynein Intermediate Chain

(2009) Justin Hall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Markovian milestoning with Voronoi tessellations

(2009) Eric Vanden-Eijnden et al.   JOURNAL OF CHEMICAL PHYSICS

Oligohis-tags: mechanisms of binding to Ni2+-NTA surfaces

(2009) Steven Knecht et al.   JOURNAL OF MOLECULAR RECOGNITION

Carbohydrate Cluster Microarrays Fabricated on Three-Dimensional Dendrimeric Platforms for Functional Glycomics Exploration

(2009) Xichun Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Multivalent ligand–receptor binding on supported lipid bilayers

(2009) Hyunsook Jung et al.   JOURNAL OF STRUCTURAL BIOLOGY

Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds

(2009) Berea A. R. Williams et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In VitroImaging andin VivoLiver Targeting with Carbohydrate Capped Quantum Dots

(2009) Raghavendra Kikkeri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multivalent Recognition of Peptides by Modular Self-Assembled Receptors

(2009) Joseph J. Reczek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Molecule Study on Intermolecular Interaction between C60and Porphyrin Derivatives: Toward Understanding the Strength of the Multivalency

(2009) Yiheng Zhang et al.   LANGMUIR

Constructing the equilibrium ensemble of folding pathways from short off-equilibrium simulations

(2009) Frank Noé et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From supramolecular chemistry to nanotechnology: Assembly of 3D nanostructures

(2009) Xing Yi Ling et al.   PURE AND APPLIED CHEMISTRY

EFFICIENT SIMULATION OF LIGAND–RECEPTOR BINDING PROCESSES USING THE CONFORMATION DYNAMICS APPROACH

(2009) ALEXANDER BUJOTZEK et al.   Journal of Bioinformatics and Computational Biology

Parallel kinetic analysis and affinity determination of hundreds of monoclonal antibodies using the ProteOn XPR36

(2008) Oded Nahshol et al.   ANALYTICAL BIOCHEMISTRY

The Influence of Ligand Valency on Aggregation Mechanisms for Inhibiting Bacterial Toxins

(2008) Cristina Sisu et al.   CHEMBIOCHEM

Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

(2008) Ilona Papp et al.   CHEMICAL COMMUNICATIONS

The Design of Polyvalent Therapeutics

(2008) Amit Joshi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Trends in Glycodendrimer Syntheses and Applications

(2008) Yoann Chabre et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Practical Routes to 2,6-Disubstituted Pyridine Derivatives

(2008) Lucie Vandromme et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Evidence for Partially Bound States in Cooperative Molecular Recognition Interfaces

(2008) Elena Chekmeneva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Small Molecule Chimera with Responsive Protein-Binding Ability

(2008) D. Calvin Harris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Architecture Effects on the Binding of Cholera Toxin by Helical Glycopolypeptides

(2008) Shuang Liu et al.   MACROMOLECULES

Controlling the activity of peptides and proteins with smart nucleic acid–protein hybrids

(2008) Lars Röglin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Switchable electrostatic interactions between gold nanoparticles and coiled coilpeptides direct colloid assembly

(2008) Sara C. Wagner et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Statistical Thermodynamics of the Stability of Multivalent Ligand-Receptor Complexes

(2008) D. J. Diestler et al.   PHYSICAL REVIEW LETTERS

The use of quantum dots in organic chemistry

(2008) Raquel E. Galian et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

The application of quantum dots, gold nanoparticles and molecular switches to optical nucleic-acid diagnostics

(2008) W. Russ Algar et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Self-Assembling Nanoparticles at Surfaces and Interfaces

(2007) Sachin Kinge et al.   CHEMPHYSCHEM

Rationally Designed Ligands that Inhibit the Aggregation of Large Gold Nanoparticles in Solution

(2007) Shishan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY