Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity

Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses

(2014) Nicole Joller et al.   IMMUNITY

Successful Administration of Ipilimumab to Two Kidney Transplantation Patients With Metastatic Melanoma

(2014) Evan J. Lipson et al.   JOURNAL OF CLINICAL ONCOLOGY

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

(2014) Christopher J Chan et al.   NATURE IMMUNOLOGY

Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers

(2013) Tsutomu Oshima et al.   Molecular Cancer

Functional Classification of Immune Regulatory Proteins

(2013) Rotem Rubinstein et al.   STRUCTURE

A role for PVRL4-driven cell–cell interactions in tumorigenesis

(2013) Natalya N Pavlova et al.   eLife

Receptors that interact with nectin and nectin-like proteins in the immunosurveillance and immunotherapy of cancer

(2012) Christopher J Chan et al.   CURRENT OPINION IN IMMUNOLOGY

The role of nectins in different types of cell-cell adhesion

(2012) Y. Rikitake et al.   JOURNAL OF CELL SCIENCE

Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226

(2012) J. Liu et al.   JOURNAL OF IMMUNOLOGY

Nectin ectodomain structures reveal a canonical adhesive interface

(2012) Oliver J Harrison et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4

(2012) Xiaoai Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion

(2012) D. Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering

(2012) K. F. Stengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thinking outside the cell: how cadherins drive adhesion

(2012) Julia Brasch et al.   TRENDS IN CELL BIOLOGY

Nectin 4 is the epithelial cell receptor for measles virus

(2012) Ryan S. Noyce et al.   TRENDS IN MICROBIOLOGY

Host factors and measles virus replication

(2012) Sebastien Delpeut et al.   Current Opinion in Virology

A Comprehensive Genetic Association Study of Alzheimer Disease in African Americans

(2011) Mark W. Logue   ARCHIVES OF NEUROLOGY

Ipilimumab: An Anti-CTLA-4 Antibody for Metastatic Melanoma

(2011) E. J. Lipson et al.   CLINICAL CANCER RESEARCH

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

(2011) Steven D. Levin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The cell adhesion gene PVRL3 is associated with congenital ocular defects

(2011) Salil A. Lachke et al.   HUMAN GENETICS

Crystal Structure of the cis-Dimer of Nectin-1

(2011) Hirotaka Narita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E–N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells

(2011) Beate K. Straub et al.   JOURNAL OF CELL BIOLOGY

Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia

(2011) M. Tanaka-Okamoto et al.   JOURNAL OF CELL SCIENCE

Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions

(2011) N. Joller et al.   JOURNAL OF IMMUNOLOGY

Nectins Establish a Checkerboard-Like Cellular Pattern in the Auditory Epithelium

(2011) H. Togashi et al.   SCIENCE

Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion

(2011) Na Zhang et al.   Nature Communications

Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1

(2011) Paolo Di Giovine et al.   PLoS Pathogens

Tumor Cell Marker PVRL4 (Nectin 4) Is an Epithelial Cell Receptor for Measles Virus

(2011) Ryan S. Noyce et al.   PLoS Pathogens

Mutations in PVRL4, Encoding Cell Adhesion Molecule Nectin-4, Cause Ectodermal Dysplasia-Syndactyly Syndrome

(2010) Francesco Brancati et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis

(2010) H. Morita et al.   DEVELOPMENT

Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth

(2010) Toshiyuki Yoshida et al.   DEVELOPMENTAL DYNAMICS

Adherens junctions: from molecules to morphogenesis

(2010) Tony J. C. Harris et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti–CTLA-4 Antibody Therapy: Immune Monitoring During Clinical Development of a Novel Immunotherapy

(2010) Margaret K. Callahan et al.   SEMINARS IN ONCOLOGY

Identification of Nectin-4 Oncoprotein as a Diagnostic and Therapeutic Target for Lung Cancer

(2009) A. Takano et al.   CANCER RESEARCH

Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese

(2009) Norihiro Takei et al.   GENOMICS

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

(2009) Tadepally Lakshmikanth et al.   JOURNAL OF CLINICAL INVESTIGATION

Linking molecular affinity and cellular specificity in cadherin-mediated adhesion

(2009) P. Katsamba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

(2009) N. Stanietsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Biochemistry of Cadherins and Catenins

(2009) L. Shapiro et al.   Cold Spring Harbor Perspectives in Biology

The Immunoglobulin-Like Cell Adhesion Molecule Nectin and Its Associated Protein Afadin

(2008) Yoshimi Takai et al.   Annual Review of Cell and Developmental Biology

CD226 Gly307Ser association with multiple autoimmune diseases

(2008) J P Hafler et al.   GENES AND IMMUNITY

Accelerated tumor growth in mice deficient in DNAM-1 receptor

(2008) Akiko Iguchi-Manaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

(2008) Xin Yu et al.   NATURE IMMUNOLOGY

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

(2008) Yoshimi Takai et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY