PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

(2016) Michelle D. Tate et al.   Scientific Reports

The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis

(2015) John C. Kash et al.   AMERICAN JOURNAL OF PATHOLOGY

Dissemination, divergence and establishment of H7N9 influenza viruses in China

(2015) Tommy Tsan-Yuk Lam et al.   NATURE

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Bird flu virus's promiscuity raises red flags

(2015) D. Normile   SCIENCE

Critical Role for the NLRP3 Inflammasome during Acute Lung Injury

(2014) J. J. Grailer et al.   JOURNAL OF IMMUNOLOGY

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

(2014) Bernardo S Franklin et al.   NATURE IMMUNOLOGY

Influenza A virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

(2014) Takuma Yoshizumi et al.   Nature Communications

Clinical, Virological, and Histopathological Manifestations of Fatal Human Infections by Avian Influenza A(H7N9) Virus

(2013) Liang Yu et al.   CLINICAL INFECTIOUS DISEASES

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

(2013) Julie L. McAuley et al.   PLoS Pathogens

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82

(2011) I. V. Alymova et al.   JOURNAL OF VIROLOGY

Differential Localization and Function of PB1-F2 Derived from Different Strains of Influenza A Virus

(2010) C.-J. Chen et al.   JOURNAL OF VIROLOGY

Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

(2010) M. D. Tate et al.   JOURNAL OF VIROLOGY

Current knowledge on PB1-F2 of influenza A viruses

(2010) Andi Krumbholz et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Influenza virus activates inflammasomes via its intracellular M2 ion channel

(2010) Takeshi Ichinohe et al.   NATURE IMMUNOLOGY

PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology

(2010) Julie L. McAuley et al.   PLoS Pathogens

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY