Potential application of cell reprogramming techniques for cancer research
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Title
Potential application of cell reprogramming techniques for cancer research
Authors
Keywords
Cancer stem cells, Epigenetics, Induced pluripotent stem cells, Organoid culture, Reactive oxygen species, Somatic cell nuclear transfer
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 76, Issue 1, Pages 45-65
Publisher
Springer Nature
Online
2018-10-03
DOI
10.1007/s00018-018-2924-7
References
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Note: Only part of the references are listed.- Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene
- (2018) X. Shawn Liu et al. CELL
- Turning up the Heat with Therapeutic Epigenome Editing
- (2018) Alexandra Zezulin et al. Cell Stem Cell
- Enhancer reprogramming in tumor progression: a new route towards cancer cell plasticity
- (2018) Luca Fagnocchi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Inhibition of Pyruvate Dehydrogenase Kinase as a Therapeutic Strategy against Cancer
- (2018) Swatishree Sradhanjali et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs
- (2018) Christian Pflueger et al. GENOME RESEARCH
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
- (2018) Robert J. Ihry et al. NATURE MEDICINE
- CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
- (2018) Emma Haapaniemi et al. NATURE MEDICINE
- Vitamin C in Stem Cell Reprogramming and Cancer
- (2018) Luisa Cimmino et al. TRENDS IN CELL BIOLOGY
- Single-Cell RNA-Sequencing in Glioma
- (2018) Eli Johnson et al. Current Oncology Reports
- MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state
- (2018) Vittoria Poli et al. Nature Communications
- Cancer epigenetics: Moving forward
- (2018) Angela Nebbioso et al. PLoS Genetics
- Stem Cell Metabolism in Cancer and Healthy Tissues: Pyruvate in the Limelight
- (2018) Cyril Corbet Frontiers in Pharmacology
- Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling
- (2018) Justin A. Colacino et al. Stem Cell Reports
- ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression
- (2017) Huanyu Zhou et al. GENES & DEVELOPMENT
- Epigenetics of epithelial-to-mesenchymal transition in pancreatic carcinoma
- (2017) Max M. Träger et al. INTERNATIONAL JOURNAL OF CANCER
- Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma
- (2017) Fahim Ahmad et al. JOURNAL OF NEUROCHEMISTRY
- Epigenetics in cancer stem cells
- (2017) Tan Boon Toh et al. Molecular Cancer
- Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
- (2017) Michalis Agathocleous et al. NATURE
- Common genetic variation drives molecular heterogeneity in human iPSCs
- (2017) Helena Kilpinen et al. NATURE
- Single-cell spatial reconstruction reveals global division of labour in the mammalian liver
- (2017) Keren Bahar Halpern et al. NATURE
- SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters
- (2017) Robert T Nakayama et al. NATURE GENETICS
- Spatial heterogeneity in medulloblastoma
- (2017) A Sorana Morrissy et al. NATURE GENETICS
- Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
- (2017) Oliver G McDonald et al. NATURE GENETICS
- Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors
- (2017) Huipeng Li et al. NATURE GENETICS
- Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
- (2017) Alice Giustacchini et al. NATURE MEDICINE
- Refining strategies to translate genome editing to the clinic
- (2017) Tatjana I Cornu et al. NATURE MEDICINE
- Tumor Heterogeneity in Pancreatic Adenocarcinoma
- (2017) Jerome Cros et al. PATHOBIOLOGY
- Disease Modeling in Stem Cell-Derived 3D Organoid Systems
- (2017) Devanjali Dutta et al. TRENDS IN MOLECULAR MEDICINE
- Li–Fraumeni Syndrome Disease Model: A Platform to Develop Precision Cancer Therapy Targeting Oncogenic p53
- (2017) Ruoji Zhou et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons
- (2017) Qi-Jie Zhang et al. Oncotarget
- Sequencing of cancer cell subpopulations identifies micrometastases in a bladder cancer patient
- (2017) Kris Prado et al. Oncotarget
- The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma
- (2017) Fangfang Jin et al. Scientific Reports
- Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons
- (2017) Orly L. Wapinski et al. Cell Reports
- Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells
- (2017) Keriayn N. Smith et al. Stem Cell Reports
- JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors
- (2017) Veena Kochat et al. PLoS One
- Looking beyond drivers and passengers in cancer genome sequencing data
- (2016) S. De et al. ANNALS OF ONCOLOGY
- Enhancer deregulation in cancer and other diseases
- (2016) Hans-Martin Herz BIOESSAYS
- Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility
- (2016) Sarah K. Denny et al. CELL
- Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution
- (2016) Hannah K. Long et al. CELL
- Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming
- (2016) Yang Zhou et al. Cell Stem Cell
- The Effect of Fetal Bovine Serum (FBS) on Efficacy of Cellular Reprogramming for Induced Pluripotent Stem Cell (iPSC) Generation
- (2016) Daekee Kwon et al. CELL TRANSPLANTATION
- Epigenetic regulation of epithelial–mesenchymal transition
- (2016) Lidong Sun et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Single-Cell Transcriptomics of the Human Endocrine Pancreas
- (2016) Yue J. Wang et al. DIABETES
- YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK–STAT3 Signaling
- (2016) Ralph Gruber et al. GASTROENTEROLOGY
- Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication
- (2016) Samantha Kaufhold et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Conundrum of Genetic “Drivers” in Benign Conditions
- (2016) Shumei Kato et al. JNCI-Journal of the National Cancer Institute
- SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
- (2016) Xiaofeng Wang et al. NATURE GENETICS
- ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice
- (2016) Radhika Mathur et al. NATURE GENETICS
- Reprogramming Enhancers in Somatic Cell Nuclear Transfer, iPSC Technology, and Direct Conversion
- (2016) Daekee Kwon et al. Stem Cell Reviews and Reports
- Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer
- (2016) Kung-Kai Kuo et al. STEM CELLS
- Influence ofATM-Mediated DNA Damage Response on Genomic Variation in Human Induced Pluripotent Stem Cells
- (2016) Junjie Lu et al. STEM CELLS AND DEVELOPMENT
- Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer
- (2016) Sophie S.W. Wang et al. Oncotarget
- The Conundrum of Genetic “Drivers” in Benign Conditions
- (2016) Shumei Kato et al. JNCI-Journal of the National Cancer Institute
- Reprogramming Enhancers in Somatic Cell Nuclear Transfer, iPSC Technology, and Direct Conversion
- (2016) Daekee Kwon et al. Stem Cell Reviews and Reports
- H1foo Has a Pivotal Role in Qualifying Induced Pluripotent Stem Cells
- (2016) Akira Kunitomi et al. Stem Cell Reports
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- (2016) Li-Chun Lu et al. Liver Cancer
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- Driver and Passenger Mutations in Cancer
- (2015) Julia R. Pon et al. Annual Review of Pathology-Mechanisms of Disease
- Modeling Familial Cancer with Induced Pluripotent Stem Cells
- (2015) Dung-Fang Lee et al. CELL
- Organoid Models of Human and Mouse Ductal Pancreatic Cancer
- (2015) Sylvia F. Boj et al. CELL
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- (2015) Young Gie Chung et al. Cell Stem Cell
- The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
- (2015) Vicki Plaks et al. Cell Stem Cell
- Emerging roles of hypoxia-inducible factors and reactive oxygen species in cancer and pluripotent stem cells
- (2015) Shigeo Saito et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity
- (2015) Alexandra Van Keymeulen et al. NATURE
- PIK3CAH1047R induces multipotency and multi-lineage mammary tumours
- (2015) Shany Koren et al. NATURE
- Three-dimensional genome architecture: players and mechanisms
- (2015) Ana Pombo et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Unraveling the 3D genome: genomics tools for multiscale exploration
- (2015) Viviana I. Risca et al. TRENDS IN GENETICS
- Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons
- (2015) Houbo Jiang et al. Nature Communications
- Predicting involvement of polycomb repressive complex 2 in direct conversion of mouse fibroblasts into induced neural stem cells
- (2015) Moein Yaqubi et al. Stem Cell Research & Therapy
- Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b
- (2015) Kyung-Rok Yu et al. Cell Reports
- Epigenetic reprogramming of melanoma cells by vitamin C treatment
- (2015) Christopher B Gustafson et al. Clinical Epigenetics
- Improved Development of Somatic Cell Cloned Mouse Embryos by Vitamin C and Latrunculin A
- (2015) Anna Mallol et al. PLoS One
- Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell
- (2015) Mayuko Nishi et al. Oncotarget
- Generation of neural progenitor cells by chemical cocktails and hypoxia
- (2014) Lin Cheng et al. CELL RESEARCH
- Cyclin D1 acts as a barrier to pluripotent reprogramming by promoting neural progenitor fate commitment
- (2014) Chih-Lung Chen et al. FEBS LETTERS
- SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
- (2014) Soufiane Boumahdi et al. NATURE
- Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
- (2014) Barbara Treutlein et al. NATURE
- Transcriptional enhancers: from properties to genome-wide predictions
- (2014) Daria Shlyueva et al. NATURE REVIEWS GENETICS
- Inhibition of TGFβ Signaling Increases Direct Conversion of Fibroblasts to Induced Cardiomyocytes
- (2014) Jamie L. Ifkovits et al. PLoS One
- Induction of Cancer Stem Cell Properties in Colon Cancer Cells by Defined Factors
- (2014) Nobu Oshima et al. PLoS One
- Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
- (2014) Kosuke Funato et al. SCIENCE
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- (2014) D. A. Jaitin et al. SCIENCE
- Enhancing the efficiency of direct reprogramming of human primary fibroblasts into dopaminergic neuron-like cells through p53 suppression
- (2014) XinJian Liu et al. Science China-Life Sciences
- The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment
- (2014) Jun Ye et al. TUMOR BIOLOGY
- Role of tumor suppressor genes in the cancer-associated reprogramming of human induced pluripotent stem cells
- (2014) Ying-Chu Lin et al. Stem Cell Research & Therapy
- Nuclear function ofAlus
- (2014) Chen Wang et al. Nucleus
- Bright/Arid3A Acts as a Barrier to Somatic Cell Reprogramming through Direct Regulation of Oct4, Sox2, and Nanog
- (2014) Melissa Popowski et al. Stem Cell Reports
- Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis
- (2013) G S Wong et al. BRITISH JOURNAL OF CANCER
- EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
- (2013) Wendy Béguelin et al. CANCER CELL
- Cerebral Organoids in a Dish: Progress and Prospects
- (2013) Marina Bershteyn et al. CELL
- Progress in the Reprogramming of Somatic Cells
- (2013) Tianhua Ma et al. CIRCULATION RESEARCH
- Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
- (2013) Su Mi Choi et al. HEPATOLOGY
- Treating Cloned Embryos, But Not Donor Cells, with 5-aza-2’-deoxycytidine Enhances the Developmental Competence of Porcine Cloned Embryos
- (2013) Yan Jun HUAN et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies
- (2013) S N Khan et al. LEUKEMIA
- Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
- (2013) Mary Jo Cantoria et al. Metabolomics
- Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put
- (2013) Jeffrey A. Simon et al. MOLECULAR CELL
- Inhibition of PTEN Tumor Suppressor Promotes the Generation of Induced Pluripotent Stem Cells
- (2013) Jiyuan Liao et al. MOLECULAR THERAPY
- NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
- (2013) Yael Costa et al. NATURE
- Tumour heterogeneity and cancer cell plasticity
- (2013) Corbin E. Meacham et al. NATURE
- Biophysical regulation of epigenetic state and cell reprogramming
- (2013) Timothy L. Downing et al. NATURE MATERIALS
- Computational approaches to identify functional genetic variants in cancer genomes
- (2013) NATURE METHODS
- Emerging patterns of somatic mutations in cancer
- (2013) Ian R. Watson et al. NATURE REVIEWS GENETICS
- Mechanisms and models of somatic cell reprogramming
- (2013) Yosef Buganim et al. NATURE REVIEWS GENETICS
- Transcriptional regulation by Polycomb group proteins
- (2013) Luciano Di Croce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Induction of cells with cancer stem cell properties from nontumorigenic human mammary epithelial cells by defined reprogramming factors
- (2013) M Nishi et al. ONCOGENE
- Direct Induction of Chondrogenic Cells from Human Dermal Fibroblast Culture by Defined Factors
- (2013) Hidetatsu Outani et al. PLoS One
- Low Oxygen Tension and Relative Defined Culture Medium with 3, 4-Dihydroxyflavone are Beneficial for Yak-Bovine Interspecies Somatic Cell Nuclear Transfer Embryo
- (2013) X Xiong et al. REPRODUCTION IN DOMESTIC ANIMALS
- Circulating Tumor Cells
- (2013) V. Plaks et al. SCIENCE
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds
- (2013) P. Hou et al. SCIENCE
- Androgen receptor-mediated apoptosis in bovine testicular induced pluripotent stem cells in response to phthalate esters
- (2013) S-W Wang et al. Cell Death & Disease
- Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis
- (2013) S Tanigawa et al. Cell Death & Disease
- An iPSC Line from Human Pancreatic Ductal Adenocarcinoma Undergoes Early to Invasive Stages of Pancreatic Cancer Progression
- (2013) Jungsun Kim et al. Cell Reports
- A Novel Small Molecule Facilitates the Reprogramming of Human Somatic Cells into a Pluripotent State and Supports the Maintenance of an Undifferentiated State of Human Pluripotent Stem Cells
- (2012) Jungwoon Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples
- (2012) K. Kumano et al. BLOOD
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Cancer stem cell dynamics in tumor progression and metastasis: Is the microenvironment to blame?
- (2012) Evelyn Fessler et al. CANCER LETTERS
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- Piglets cloned from induced pluripotent stem cells
- (2012) Nana Fan et al. CELL RESEARCH
- Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal
- (2012) Jin Zhang et al. Cell Stem Cell
- Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor
- (2012) Karen L. Ring et al. Cell Stem Cell
- Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
- (2012) H Yang et al. ONCOGENE
- Serum Starvation Induced Cell Cycle Synchronization Facilitates Human Somatic Cells Reprogramming
- (2012) Mengfei Chen et al. PLoS One
- Increased cleavage rate of human nuclear transfer embryos after 5-aza-2′-deoxycytidine treatment
- (2012) Lei Sun et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Neural Stem Cells Directly Differentiated from Partially Reprogrammed Fibroblasts Rapidly Acquire Gliogenic Competency
- (2012) Takeshi Matsui et al. STEM CELLS
- iPSCs from cancer cells: challenges and opportunities
- (2012) Verónica Ramos-Mejia et al. TRENDS IN MOLECULAR MEDICINE
- Epigenetic modification of fetal fibroblasts improves developmental competency and gene expression in porcine cloned embryos
- (2012) B. Mohana Kumar et al. VETERINARY RESEARCH COMMUNICATIONS
- Vitamin C enhances in vitro and in vivo development of porcine somatic cell nuclear transfer embryos
- (2011) Yongye Huang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells
- (2011) J. Mathieu et al. CANCER RESEARCH
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
- (2011) Athanasia D Panopoulos et al. CELL RESEARCH
- Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells
- (2011) Lan-Lan Smith et al. Cell Stem Cell
- Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons
- (2011) Samuele Marro et al. Cell Stem Cell
- Scriptaid Improves In Vitro Development and Nuclear Reprogramming of Somatic Cell Nuclear Transfer Bovine Embryos
- (2011) Li-Jun Wang et al. Cellular Reprogramming
- Human pluripotent stem cells decouple respiration from energy production
- (2011) Ng Shyh-Chang et al. EMBO JOURNAL
- Breast cancer stem cells, cytokine networks, and the tumor microenvironment
- (2011) Hasan Korkaya et al. JOURNAL OF CLINICAL INVESTIGATION
- Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells
- (2011) J Yuan et al. LEUKEMIA
- Direct lineage conversions: unnatural but useful?
- (2011) Thomas Vierbuchen et al. NATURE BIOTECHNOLOGY
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- (2011) Paola Scaffidi et al. NATURE CELL BIOLOGY
- Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin
- (2011) Vanniarajan Ayyasamy et al. PLoS One
- Long-term culture following ES-like gene-induced reprogramming elicits an aggressive phenotype in mutated cholangiocellular carcinoma cells
- (2010) Ken-ichi Nagai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- AID in reprogramming: Quick and efficient
- (2010) Wenbin Deng BIOESSAYS
- Generation of iPSCs from cultured human malignant cells
- (2010) J. E. Carette et al. BLOOD
- Reprogramming cell fates in the mammary microenvironment
- (2010) Corinne A. Boulanger et al. CELL CYCLE
- Stem Cells and the Niche: A Dynamic Duo
- (2010) Justin Voog et al. Cell Stem Cell
- Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells
- (2010) Miguel Angel Esteban et al. Cell Stem Cell
- Will iPS Cells Enhance Therapeutic Applicability of Cord Blood Cells and Banking?
- (2010) Hal E. Broxmeyer Cell Stem Cell
- A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts
- (2010) Ronghui Li et al. Cell Stem Cell
- Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming
- (2010) Payman Samavarchi-Tehrani et al. Cell Stem Cell
- Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
- (2010) Rachel Sarig et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Distant metastasis occurs late during the genetic evolution of pancreatic cancer
- (2010) Shinichi Yachida et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- Advances in understanding cancer genomes through second-generation sequencing
- (2010) Matthew Meyerson et al. NATURE REVIEWS GENETICS
- Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer
- (2010) S Peng et al. ONCOGENE
- E-Cadherin-Mediated Cell-Cell Contact Is Critical for Induced Pluripotent Stem Cell Generation
- (2010) Taotao Chen et al. STEM CELLS
- The Biology of Chromatin Remodeling Complexes
- (2009) Cedric R. Clapier et al. Annual Review of Biochemistry
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
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- (2009) Krishanu Saha et al. Cell Stem Cell
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- (2009) Yoshinori Yoshida et al. Cell Stem Cell
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- (2009) Justin K. Ichida et al. Cell Stem Cell
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- (2009) Nimet Maherali et al. CURRENT BIOLOGY
- BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal
- (2009) M. Abdouh et al. JOURNAL OF NEUROSCIENCE
- The promises and perils of p53
- (2009) Valery Krizhanovsky et al. NATURE
- A role for Lin28 in primordial germ-cell development and germ-cell malignancy
- (2009) Jason A. West et al. NATURE
- Linking the p53 tumour suppressor pathway to somatic cell reprogramming
- (2009) Teruhisa Kawamura et al. NATURE
- A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
- (2009) Rosa M. Marión et al. NATURE
- Direct cell reprogramming is a stochastic process amenable to acceleration
- (2009) Jacob Hanna et al. NATURE
- Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
- (2009) Jochen Utikal et al. NATURE
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- (2009) Han Li et al. NATURE
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- (2009) Nidhi Bhutani et al. NATURE
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- (2009) Chunyuan Jin et al. NATURE GENETICS
- A chemical platform for improved induction of human iPSCs
- (2009) Tongxiang Lin et al. NATURE METHODS
- Defined factors induce reprogramming of gastrointestinal cancer cells
- (2009) N. Miyoshi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficiency of SCNT Buffalo (Bubalus bubalis) Embryos in Different Culture Medium and Analysis of mRNA Expression of Insulin-like Growth Factors During Embryogenesis
- (2009) A Pandey et al. REPRODUCTION IN DOMESTIC ANIMALS
- Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain
- (2009) S. Varum et al. Stem Cell Research
- Generation of Pig Induced Pluripotent Stem Cells with a Drug-Inducible System
- (2009) Zhao Wu et al. Journal of Molecular Cell Biology
- Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
- (2008) Stéphane Ansieau et al. CANCER CELL
- Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation
- (2008) Yang Zhao et al. Cell Stem Cell
- A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells
- (2008) Nimet Maherali et al. Cell Stem Cell
- Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors
- (2008) Wenlin Li et al. Cell Stem Cell
- Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell Survival
- (2008) Liping Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer
- (2008) Yupeng Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- (2008) Qiao Zhou et al. NATURE
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- Dissecting direct reprogramming through integrative genomic analysis
- (2008) Tarjei S. Mikkelsen et al. NATURE
- Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
- (2008) Yutaka Kondo et al. NATURE GENETICS
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
- Mitochondria in early mammalian development
- (2008) Jonathan Van Blerkom SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Co-evolution of tumor cells and their microenvironment
- (2008) Kornelia Polyak et al. TRENDS IN GENETICS
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