Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms

Of dogs and hookworms: man’s best friend and his parasites as a model for translational biomedical research

(2018) Catherine Shepherd et al.   Parasites & Vectors

Tackling Hypotheticals in Helminth Genomes

(2018) Nikola Palevich et al.   TRENDS IN PARASITOLOGY

Cysteine proteases as digestive enzymes in parasitic helminths

(2018) Conor R. Caffrey et al.   PLoS Neglected Tropical Diseases

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

(2018) Rick M. Maizels et al.   IMMUNITY

WormBase ParaSite − a comprehensive resource for helminth genomics

(2017) Kevin L. Howe et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Revisiting the Ancylostoma Caninum Secretome Provides New Information on Hookworm-Host Interactions

(2017) Taylor Morante et al.   PROTEOMICS

Exploiting Helminth–Host Interactomes through Big Data

(2017) Javier Sotillo et al.   TRENDS IN PARASITOLOGY

Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults

(2017) David J. Diemert et al.   PLoS Neglected Tropical Diseases

Host parasite communications—Messages from helminths for the immune system

(2016) Gillian Coakley et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The genomic basis of parasitism in the Strongyloides clade of nematodes

(2016) Vicky L Hunt et al.   NATURE GENETICS

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

(2016) S. Navarro et al.   Science Translational Medicine

Advancing a vaccine to prevent hookworm disease and anemia

(2016) Peter J. Hotez et al.   VACCINE

Hookworm infection

(2016) Alex Loukas et al.   Nature Reviews Disease Primers

BRAKER1: Unsupervised RNA-Seq-Based Genome Annotation with GeneMark-ET and AUGUSTUS: Table 1.

(2015) Katharina J. Hoff et al.   BIOINFORMATICS

BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs

(2015) Felipe A. Simão et al.   BIOINFORMATICS

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families

(2015) Erich M Schwarz et al.   NATURE GENETICS

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Repbase Update, a database of repetitive elements in eukaryotic genomes

(2015) Weidong Bao et al.   Mobile DNA

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

InterProScan 5: genome-scale protein function classification

(2014) P. Jones et al.   BIOINFORMATICS

Secreted Proteomes of Different Developmental Stages of the Gastrointestinal NematodeNippostrongylus brasiliensis

(2014) Javier Sotillo et al.   MOLECULAR & CELLULAR PROTEOMICS

Genome of the human hookworm Necator americanus

(2014) Yat T Tang et al.   NATURE GENETICS

Proteogenomics: concepts, applications and computational strategies

(2014) Alexey I Nesvizhskii   NATURE METHODS

Helminth.net: expansions to Nematode.net and an introduction to Trematode.net

(2014) John Martin et al.   NUCLEIC ACIDS RESEARCH

Integration of mapped RNA-Seq reads into automatic training of eukaryotic gene finding algorithm

(2014) Alexandre Lomsadze et al.   NUCLEIC ACIDS RESEARCH

What helminth genomes have taught us about parasite evolution

(2014) MAGDALENA ZAROWIECKI et al.   PARASITOLOGY

Combining Results of Multiple Search Engines in Proteomics

(2013) David Shteynberg et al.   MOLECULAR & CELLULAR PROTEOMICS

MAKER-P: A Tool Kit for the Rapid Creation, Management, and Quality Control of Plant Genome Annotations

(2013) M. S. Campbell et al.   PLANT PHYSIOLOGY

The Human Hookworm Vaccine

(2013) Peter J. Hotez et al.   VACCINE

Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

(2013) James P. Hewitson et al.   PLoS Pathogens

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

Epidemiological and Genetic Data Supporting the Transmission of Ancylostoma ceylanicum among Human and Domestic Animals

(2012) Romano Ngui et al.   PLoS Neglected Tropical Diseases

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier

(2012) Sumaira Z. Hasnain et al.   PLoS Neglected Tropical Diseases

A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni

(2012) Anna V. Protasio et al.   PLoS Neglected Tropical Diseases

MAKER2: an annotation pipeline and genome-database management tool for second-generation genome projects

(2011) Carson Holt et al.   BMC BIOINFORMATICS

Hookworm products ameliorate dextran sodium sulfate-induced colitis in BALB/c mice

(2011) Guilherme Grossi Lopes Cançado et al.   INFLAMMATORY BOWEL DISEASES

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

(2011) James P. Hewitson et al.   Journal of Proteomics

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation

(2010) Zhengyuan Wang et al.   BMC GENOMICS

Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models

(2010) N. Borchert et al.   GENOME RESEARCH

Developing vaccines to combat hookworm infection and intestinal schistosomiasis

(2010) Peter J. Hotez et al.   NATURE REVIEWS MICROBIOLOGY

Massively Parallel Sequencing and Analysis of the Necator americanus Transcriptome

(2010) Cinzia Cantacessi et al.   PLoS Neglected Tropical Diseases

A portrait of the “SCP/TAPS” proteins of eukaryotes — Developing a framework for fundamental research and biotechnological outcomes

(2009) C. Cantacessi et al.   BIOTECHNOLOGY ADVANCES

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Proteolytic Degradation of Hemoglobin in the Intestine of the Human HookwormNecator americanus

(2009) Najju Ranjit et al.   JOURNAL OF INFECTIOUS DISEASES

Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity

(2009) James P. Hewitson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Hookworm and Poverty

(2008) Peter Hotez   Annals of the New York Academy of Sciences

Using native and syntenically mapped cDNA alignments to improve de novo gene finding

(2008) Mario Stanke et al.   BIOINFORMATICS

Proteomics Analysis of the Excretory/Secretory Component of the Blood-feeding Stage of the Hookworm,Ancylostoma caninum

(2008) Jason Mulvenna et al.   MOLECULAR & CELLULAR PROTEOMICS

A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus

(2008) Najju Ranjit et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 Hookworm Vaccine in unexposed adults

(2008) Jeffrey M. Bethony et al.   VACCINE

Hookworm-Related Anaemia among Pregnant Women: A Systematic Review

(2008) Simon Brooker et al.   PLoS Neglected Tropical Diseases