Secreted Proteomes of Different Developmental Stages of the Gastrointestinal NematodeNippostrongylus brasiliensis

Genome of the human hookworm Necator americanus

(2014) Yat T Tang et al.   NATURE GENETICS

Molecular cloning and characterisation of in vitro immune response against astacin-like metalloprotease Ace-MTP-2 from Ancylostoma ceylanicum

(2013) Piotr Bąska et al.   EXPERIMENTAL PARASITOLOGY

The transcriptome of Echinostoma caproni adults: Further characterization of the secretome and identification of new potential drug targets

(2013) Gagan Garg et al.   Journal of Proteomics

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis

(2013) Brian J Haas et al.   Nature Protocols

TIMPs of parasitic helminths – a large-scale analysis of high-throughput sequence datasets

(2013) Cinzia Cantacessi et al.   Parasites & Vectors

Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

(2013) James P. Hewitson et al.   PLoS Pathogens

Development of CD4 T Cell Dependent Immunity Against N. brasiliensis Infection

(2013) Marina Harvie et al.   Frontiers in Immunology

Helminth Infections and Host Immune Regulation

(2012) H. J. McSorley et al.   CLINICAL MICROBIOLOGY REVIEWS

The hookworm pharmacopoeia for inflammatory diseases

(2012) Severine Navarro et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: Implications for the development of vaccines against helminths

(2012) David J. Diemert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Deep Exploration of the Transcriptome and “Excretory/Secretory” Proteome of AdultFascioloides magna

(2012) Cinzia Cantacessi et al.   MOLECULAR & CELLULAR PROTEOMICS

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

(2012) Antonio Marcilla et al.   PLoS One

Hookworm SCP/TAPS protein structure—A key to understanding host–parasite interactions and developing new interventions

(2011) Asiah Osman et al.   BIOTECHNOLOGY ADVANCES

Characterization of Angiostrongylus cantonensis excretory–secretory proteins as potential diagnostic targets

(2011) Alessandra L. Morassutti et al.   EXPERIMENTAL PARASITOLOGY

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

(2011) James P. Hewitson et al.   Journal of Proteomics

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

HMMER web server: interactive sequence similarity searching

(2011) R. D. Finn et al.   NUCLEIC ACIDS RESEARCH

A calcium-activated apyrase from Teladorsagia circumcincta: an excretory/secretory antigen capable of modulating host immune responses?

(2011) A. J. NISBET et al.   PARASITE IMMUNOLOGY

Protist-Type Lysozymes of the Nematode Caenorhabditis elegans Contribute to Resistance against Pathogenic Bacillus thuringiensis

(2011) Claudia Boehnisch et al.   PLoS One

A Portrait of the Transcriptome of the Neglected Trematode, Fasciola gigantica—Biological and Biotechnological Implications

(2011) Neil D. Young et al.   PLoS Neglected Tropical Diseases

The Lung Is an Important Site for Priming CD4 T-Cell-Mediated Protective Immunity against Gastrointestinal Helminth Parasites

(2010) M. Harvie et al.   INFECTION AND IMMUNITY

Strongyloides stercoralis excretory/secretory protein strongylastacin specifically recognized by IgE antibodies in infected human sera

(2010) Ravi Varatharajalu et al.   MICROBIOLOGY AND IMMUNOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes

(2010) GILLIAN STEPEK et al.   PARASITOLOGY

A calcium-activated nucleotidase secreted from Ostertagia ostertagi 4th-stage larvae is a member of the novel salivary apyrases present in blood-feeding arthropods

(2010) D. S. ZARLENGA et al.   PARASITOLOGY

Excretory/secretory proteome of the adult stage of Echinostoma caproni

(2010) Javier Sotillo et al.   PARASITOLOGY RESEARCH

Scaffold: A bioinformatic tool for validating MS/MS-based proteomic studies

(2010) Brian C. Searle   PROTEOMICS

Massively Parallel Sequencing and Analysis of the Necator americanus Transcriptome

(2010) Cinzia Cantacessi et al.   PLoS Neglected Tropical Diseases

A portrait of the “SCP/TAPS” proteins of eukaryotes — Developing a framework for fundamental research and biotechnological outcomes

(2009) C. Cantacessi et al.   BIOTECHNOLOGY ADVANCES

Recombinant Ov-ASP-1, a Th1-Biased Protein Adjuvant Derived from the Helminth Onchocerca volvulus, Can Directly Bind and Activate Antigen-Presenting Cells

(2009) Y. He et al.   JOURNAL OF IMMUNOLOGY

Basophils Protect against Reinfection with Hookworms Independently of Mast Cells and Memory Th2 Cells

(2009) Caspar Ohnmacht et al.   JOURNAL OF IMMUNOLOGY

Rescuing the bottom billion through control of neglected tropical diseases

(2009) Peter J Hotez et al.   LANCET

Brugia malayi Excreted/Secreted Proteins at the Host/Parasite Interface: Stage- and Gender-Specific Proteomic Profiling

(2009) Sasisekhar Bennuru et al.   PLoS Neglected Tropical Diseases

The Hookworm Tissue Inhibitor of Metalloproteases (Ac-TMP-1) Modifies Dendritic Cell Function and Induces Generation of CD4 and CD8 Suppressor T Cells

(2009) Carmen Cuéllar et al.   PLoS Neglected Tropical Diseases

Hookworm-Induced Persistent Changes to the Immunological Environment of the Lung

(2008) J. J. Reece et al.   INFECTION AND IMMUNITY

Proteomics Analysis of the Excretory/Secretory Component of the Blood-feeding Stage of the Hookworm,Ancylostoma caninum

(2008) Jason Mulvenna et al.   MOLECULAR & CELLULAR PROTEOMICS

The secretome of the filarial parasite, Brugia malayi: Proteomic profile of adult excretory–secretory products

(2008) James P. Hewitson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Identification of antigenic proteins from Echinostoma caproni (Trematoda) recognized by mouse immunoglobulins M, A and G using an immunoproteomic approach

(2008) J. SOTILLO et al.   PARASITE IMMUNOLOGY

Necator americanus: The Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro

(2007) Molly A. Bower et al.   EXPERIMENTAL PARASITOLOGY