Nutraceuticals Targeting Generation and Oxidant Activity of Peroxynitrite May Aid Prevention and Control of Parkinson’s Disease

The Novel Dual GLP-1/GIP Receptor Agonist DA-CH5 Is Superior to Single GLP-1 Receptor Agonists in the MPTP Model of Parkinson’s Disease

(2020) Lingyu Zhang et al.   Journal of Parkinsons Disease

Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetes

(2020) Munehiro Kitada et al.   Aging-US

Docosahexaenoic acid protects motor function and increases dopamine synthesis in a rat model of Parkinson's disease via mechanisms associated with increased protein kinase activity in the striatum

(2020) Neha Milind Chitre et al.   NEUROPHARMACOLOGY

Astaxanthin suppresses endoplasmic reticulum stress and protects against neuron damage in Parkinson's disease by regulating miR-7/SNCA axis

(2020) Dong-Fang Shen et al.   NEUROSCIENCE RESEARCH

Comprehensive assessment of PINK1 variants in Parkinson's disease

(2020) Lynne Krohn et al.   NEUROBIOLOGY OF AGING

Gout and the risk of Parkinson’s disease in older adults: a study of U.S. Medicare data

(2019) Jasvinder A. Singh et al.   BMC Neurology

Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice

(2019) Zhiping Ren et al.   JOURNAL OF IMMUNOLOGY

Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson’s Disease Mice via Gut Microbiota and Metabolites

(2019) Zhi-Lan Zhou et al.   Neurotherapeutics

Methionine restriction prevents onset of type 2 diabetes in NZO mice

(2019) Teresa Castaño-Martinez et al.   FASEB JOURNAL

Evidence for a Role for Sestrin1 in Mediating Leucine-Induced Activation of mTORC1 in Skeletal Muscle

(2019) Dandan Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

GLP-1’s role in neuroprotection: a systematic review

(2019) Damla Erbil et al.   BRAIN INJURY

Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease

(2019) Runxiao Lv et al.   LIFE SCIENCES

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

(2019) Sunil Srivastav et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy

(2019) Matteo Bordi et al.   Cell Death & Disease

Neuroprotective Effects of Brain-Gut Peptides: A Potential Therapy for Parkinson’s Disease

(2019) Dong Dong et al.   Neuroscience Bulletin

Potential of Prebiotic Butyrogenic Fibers in Parkinson's Disease

(2019) Thaisa M. Cantu-Jungles et al.   Frontiers in Neurology

Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment

(2019) Richard A. Maki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Omega-3 Fatty Acids and Neurodegenerative Diseases: New Evidence in Clinical Trials

(2019) Rossella Avallone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sensors for the mTORC1 pathway regulated by amino acids

(2019) Xiu-zhi Li et al.   Journal of Zhejiang University-SCIENCE B

Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease

(2019) Paraskevi Krashia et al.   Nature Communications

Glucagon-Like Peptide-1: A Focus on Neurodegenerative Diseases

(2019) Maddalena Grieco et al.   Frontiers in Neuroscience

MiR-146b protects against the inflammation injury in pediatric pneumonia through MyD88/NF-κB signaling pathway

(2019) Lei Zhang et al.   Infectious Diseases

Glucagon-like peptide-1 receptor agonist exendin-4 mitigates lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages

(2019) Canrong Lu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neuroprotective effects of docosahexaenoic acid against sub-acute manganese intoxication induced dopaminergic and motor disorders in mice

(2019) Radouane El Fari et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Mechanism of the neuroprotective effect of GLP-1 in a rat model of Parkinson's with pre-existing diabetes

(2019) Eman A. Elbassuoni et al.   NEUROCHEMISTRY INTERNATIONAL

Diet in Parkinson's Disease: Critical Role for the Microbiome

(2019) Aeja Jackson et al.   Frontiers in Neurology

Higher spermidine intake is linked to lower mortality: a prospective population-based study

(2018) Stefan Kiechl et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Taurine protects noradrenergic locus coeruleus neurons in a mouse Parkinson’s disease model by inhibiting microglial M1 polarization

(2018) Liyan Hou et al.   AMINO ACIDS

Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson’s disease

(2018) Akio Nakashima et al.   BEHAVIOURAL PHARMACOLOGY

S100B polymorphisms are associated with age of onset of Parkinson’s disease

(2018) Camilla Fardell et al.   BMC Medical Genetics

Impaired CBS-H 2 S signaling axis contributes to MPTP-induced neurodegeneration in a mouse model of Parkinson’s disease

(2018) Yu-Qing Yuan et al.   BRAIN BEHAVIOR AND IMMUNITY

Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment

(2018) Shireen Chikara et al.   CANCER LETTERS

Beneficial Effects of Flavonoids Against Parkinson's Disease

(2018) Un Ju Jung et al.   JOURNAL OF MEDICINAL FOOD

Ferulic acid may target MyD88-mediated pro-inflammatory signaling – Implications for the health protection afforded by whole grains, anthocyanins, and coffee

(2018) Mark F. McCarty et al.   MEDICAL HYPOTHESES

Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs

(2018) Elisa Bisicchia et al.   MOLECULAR NEUROBIOLOGY

Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease

(2018) Simonetta Camandola et al.   NEUROCHEMICAL RESEARCH

Neuroprotective potential of spermidine against rotenone induced Parkinson's disease in rats

(2018) Sunaina Sharma et al.   NEUROCHEMISTRY INTERNATIONAL

RAGE and its emerging role in the pathogenesis of Parkinson’s disease

(2018) Xiuli Jiang et al.   NEUROSCIENCE LETTERS

Spermidine in health and disease

(2018) Frank Madeo et al.   SCIENCE

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

(2018) Yuning Che et al.   Cell Death & Disease

Ferulic Acid Supplementation Improves Lipid Profiles, Oxidative Stress, and Inflammatory Status in Hyperlipidemic Subjects: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

(2018) Akkarach Bumrungpert et al.   Nutrients

Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway

(2018) Liyan Hou et al.   Redox Biology

Cerebrospinal fluid markers analysis in the differential diagnosis of dementia with Lewy bodies and Parkinson’s disease dementia

(2018) Karin Gmitterová et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review

(2018) Suhn Kim et al.   Nutrients

Triglyceride Form of Docosahexaenoic Acid Mediates Neuroprotection in Experimental Parkinsonism

(2018) Maricel Gómez-Soler et al.   Frontiers in Neuroscience

Spermidine reduces cancer-related mortality in humans

(2018) Federico Pietrocola et al.   Autophagy

Glial GLP1R: A novel neuroprotector?

(2018) Aubrey M. Schonhoff et al.   MOVEMENT DISORDERS

Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation

(2018) Sara Hernando et al.   NEUROBIOLOGY OF DISEASE

Docosahexaenoic acid protection in a rotenone induced Parkinson's model: Prevention of tubulin and synaptophysin loss, but no association with mitochondrial function

(2018) Norma Serrano-García et al.   NEUROCHEMISTRY INTERNATIONAL

Endogenous hydrogen sulfide-mediated MAPK inhibition preserves endothelial function through TXNIP signaling

(2017) Danyang Tian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigallocatechin-3-gallate inhibits TLR4 signaling through the 67-kDa laminin receptor and effectively alleviates acute lung injury induced by H9N2 swine influenza virus

(2017) Ming-ju Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo

(2017) Zhongkun Ren et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Lower Affinity of Isradipine for L-Type Ca 2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease

(2017) Nadine J. Ortner et al.   JOURNAL OF NEUROSCIENCE

Epigallocatechin Gallate Has a Neurorescue Effect in a Mouse Model of Parkinson Disease

(2017) Qi Xu et al.   JOURNAL OF NUTRITION

Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1

(2017) Jiaming Liu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

One year safety and efficacy of inosine to increase the serum urate level for patients with Parkinson's disease in Japan

(2017) Hirotaka Iwaki et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Effects of MgSO 4 and magnesium transporters on 6-hydroxydopamine-induced SH-SY5Y cells

(2017) Ling Lin et al.   LIFE SCIENCES

The significance of uric acid in the diagnosis and treatment of Parkinson disease

(2017) Zhange Yu et al.   MEDICINE

MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling

(2017) Alberto Bartolomé et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of Glucagon-Like Peptide-1 Receptor Promotes Neuroprotection in Experimental Autoimmune Encephalomyelitis by Reducing Neuroinflammatory Responses

(2017) Chi-Ho Lee et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective Activities of Spirulina platensis in the 6-OHDA Model of Parkinson’s Disease Are Related to Its Anti-Inflammatory Effects

(2017) Francisco Arnaldo Viana Lima et al.   NEUROCHEMICAL RESEARCH

Gut–brain and brain–gut axis in Parkinson's disease models: Effects of a uridine and fish oil diet

(2017) Paula Perez-Pardo et al.   NUTRITIONAL NEUROSCIENCE

Neuroprotective effect of omega-3 polyunsaturated fatty acids in the 6-OHDA model of Parkinson's disease is mediated by a reduction of inducible nitric oxide synthase

(2017) Marco Aurélio Mori et al.   NUTRITIONAL NEUROSCIENCE

A 2B adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway

(2017) Stefania Merighi et al.   PHARMACOLOGICAL RESEARCH

SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway

(2017) Xin Gu et al.   SCIENCE

Astaxanthin is neuroprotective in an aged mouse model of Parkinson’s disease

(2017) Beth Grimmig et al.   Oncotarget

Targeted inhibition of RAGE in substantia nigra of rats blocks 6-OHDA–induced dopaminergic denervation

(2017) Juciano Gasparotto et al.   Scientific Reports

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models

(2017) Chang-Ki Oh et al.   Cell Reports

Protein-Restricted Diets for Ameliorating Motor Fluctuations in Parkinson's Disease

(2017) Luxi Wang et al.   Frontiers in Aging Neuroscience

Resolvin D1 Attenuates Mpp+-Induced Parkinson Disease via Inhibiting Inflammation in PC12 Cells

(2017) Jinyan Xu et al.   MEDICAL SCIENCE MONITOR

PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease

(2017) Francois Mouton-Liger et al.   Frontiers in Molecular Neuroscience

GYY4137, an H2S Slow-Releasing Donor, Prevents Nitrative Stress and α-Synuclein Nitration in an MPTP Mouse Model of Parkinson’s Disease

(2017) Xiaoou Hou et al.   Frontiers in Pharmacology

Decreased circulating Zinc levels in Parkinson’s disease: a meta-analysis study

(2017) Ke Du et al.   Scientific Reports

Alpha-synuclein activates BV2 microglia dependent on its aggregation state

(2016) Alana Hoffmann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

(2016) Lynne Chantranupong et al.   CELL

Calcium Channel Antagonists as Disease-Modifying Therapy for Parkinson’s Disease: Therapeutic Rationale and Current Status

(2016) Tara Swart et al.   CNS DRUGS

Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration

(2016) Shih-Heng Chen et al.   CURRENT OPINION IN PHARMACOLOGY

Medical Application ofSpirulina platensisDerived C-Phycocyanin

(2016) Qian Liu et al.   Evidence-based Complementary and Alternative Medicine

Anti-high mobility group box 1 antibody exerts neuroprotection in a rat model of Parkinson's disease

(2016) Tatsuya Sasaki et al.   EXPERIMENTAL NEUROLOGY

Hypochlorite converts cysteinyl-dopamine into a cytotoxic product: A possible factor in Parkinson's Disease

(2016) Nihar J. Mehta et al.   FREE RADICAL BIOLOGY AND MEDICINE

Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension

(2016) Qianqian Sun et al.   HYPERTENSION

Inhibitory effects of omega-3 fatty acids on early brain injury after subarachnoid hemorrhage in rats: Possible involvement of G protein-coupled receptor 120/β-arrestin2/TGF-β activated kinase-1 binding protein-1 signaling pathway

(2016) Jia Yin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases

(2016) Moonhee Lee et al.   Journal of Neuroinflammation

Partial neurorescue effects of DHA following a 6-OHDA lesion of the mouse dopaminergic system

(2016) Katherine Coulombe et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc

(2016) J. E. J. Hardyman et al.   Metallomics

Mechanism of arginine sensing by CASTOR1 upstream of mTORC1

(2016) Robert A. Saxton et al.   NATURE

In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin

(2016) Matteo Santoro et al.   NEUROBIOLOGY OF DISEASE

The protective mechanism of docosahexaenoic acid in mouse model of Parkinson: The role of heme oxygenase

(2016) Ayse Ozkan et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotection by caffeine in the MPTP model of parkinson’s disease and its dependence on adenosine A 2A receptors

(2016) K. Xu et al.   NEUROSCIENCE

Role of adenosine A2A receptor in cerebral ischemia reperfusion injury: Signaling to phosphorylated extracellular signal-regulated protein kinase (pERK1/2)

(2016) R.A. Mohamed et al.   NEUROSCIENCE

Exenatide (a GLP-1 agonist) expresses anti-inflammatory properties in cultured human monocytes/macrophages in a protein kinase A and B/Akt manner

(2016) Łukasz Bułdak et al.   Pharmacological Reports

Sestrin regulation of TORC1: Is Sestrin a leucine sensor?

(2016) Jun Hee Lee et al.   Science Signaling

Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons

(2016) Thomas M. Jeitner et al.   TOXICOLOGICAL SCIENCES

Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation

(2016) Rudolf Wedmann et al.   Chemical Science

Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health

(2016) Luigi Fontana et al.   Cell Reports

Environmental Exposures and Parkinson’s Disease

(2016) Sirisha Nandipati et al.   International Journal of Environmental Research and Public Health

TLR4 Signaling in MPP+-Induced Activation of BV-2 Cells

(2016) Peng Zhou et al.   NEURAL PLASTICITY

Sestrin regulation of TORC1: Is Sestrin a leucine sensor?

(2016) Jun Hee Lee et al.   Science Signaling

Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies

(2016) Alexandre N. Rcom-H'cheo-Gauthier et al.   Frontiers in Neuroscience

Ferulic Acid Regulates the Nrf2/Heme Oxygenase-1 System and Counteracts Trimethyltin-Induced Neuronal Damage in the Human Neuroblastoma Cell Line SH-SY5Y

(2016) Stefania Catino et al.   Frontiers in Pharmacology

Resolvin D2 recovers neural injury by suppressing inflammatory mediators expression in lipopolysaccharide-induced Parkinson's disease rat model

(2015) Yuguang Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intracellular magnesium level determines cell viability in the MPP+ model of Parkinson's disease

(2015) Yutaka Shindo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson’s disease

(2015) Aurelija Jucaite et al.   BRAIN

The Docosanoid Neuroprotectin D1 Induces TH-Positive Neuronal Survival in a Cellular Model of Parkinson’s Disease

(2015) Jorgelina M. Calandria et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Increased bilirubin levels inde novoParkinson's disease

(2015) M. Moccia et al.   EUROPEAN JOURNAL OF NEUROLOGY

Inducible nitric oxide synthase (iNOS) regulatory region variation in non-human primates

(2015) Morteza Roodgar et al.   INFECTION GENETICS AND EVOLUTION

Epigallocatechin Gallate (EGCG) Suppresses Lipopolysaccharide-Induced Toll-like Receptor 4 (TLR4) Activity via 67 kDa Laminin Receptor (67LR) in 3T3-L1 Adipocytes

(2015) Suqing Bao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary modifications in Parkinson’s disease: A neuroprotective intervention?

(2015) Shital P. Shah et al.   MEDICAL HYPOTHESES

Ferulic Acid Protects Against Lead Acetate-Induced Inhibition of Neurite Outgrowth by Upregulating HO-1 in PC12 Cells: Involvement of ERK1/2-Nrf2 Pathway

(2015) Chun-Lei Yu et al.   MOLECULAR NEUROBIOLOGY

Formation and Implications of Alpha-Synuclein Radical in Maneb- and Paraquat-Induced Models of Parkinson’s Disease

(2015) Ashutosh Kumar et al.   MOLECULAR NEUROBIOLOGY

Parkinson's disease research in a prospective cohort in China

(2015) Honglei Chen et al.   PARKINSONISM & RELATED DISORDERS

Gout is not associated with a lower risk of Parkinson's disease: A systematic review and meta-analysis

(2015) Patompong Ungprasert et al.   PARKINSONISM & RELATED DISORDERS

Ferulic acid pretreatment mitigates MPTP-induced motor impairment and histopathological alterations in C57BL/6 mice

(2015) Sangeetha Nagarajan et al.   PHARMACEUTICAL BIOLOGY

The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity

(2015) Buvana Ravishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration

(2015) Daniel A. Stevens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RAGE-ligands axis: A new ‘driving force’ for cigarette smoke-induced airway inflammation in COPD?

(2015) Min Li et al.   RESPIROLOGY

Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

(2015) Stefano G. Daniele et al.   Science Signaling

Neuroprotective potential of ferulic acid in the rotenone model of Parkinson’s disease

(2015) Emdadul Haque et al.   Drug Design Development and Therapy

Associations between Vitamin D Status, Supplementation, Outdoor Work and Risk of Parkinson’s Disease: A Meta-Analysis Assessment

(2015) Liang Shen et al.   Nutrients

Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

(2015) Stefano G. Daniele et al.   Science Signaling

Bilirubin inhibits the up-regulation of inducible nitric oxide synthase by scavenging reactive oxygen species generated by the toll-like receptor 4-dependent activation of NADPH oxidase

(2015) Gila Idelman et al.   Redox Biology

Toll-Like Receptor Expression in the Blood and Brain of Patients and a Mouse Model of Parkinson's Disease

(2015) J. Drouin-Ouellet et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Calcium signaling in Parkinson’s disease

(2014) Tito Calì et al.   CELL AND TISSUE RESEARCH

Lower Serum Bilirubin and Uric Acid Concentrations in Patients with Parkinson’s Disease in China

(2014) Xiao-ling Qin et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Dairy foods intake and risk of Parkinson’s disease: a dose–response meta-analysis of prospective cohort studies

(2014) Wenjie Jiang et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Epigallocatechin-3-gallate-mediated Tollip induction through the 67-kDa laminin receptor negatively regulating TLR4 signaling in endothelial cells

(2014) Eui-Baek Byun et al.   IMMUNOBIOLOGY

FGF21 is an endocrine signal of protein restriction

(2014) Thomas Laeger et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson's Disease

(2014) X. Hu et al.   JOURNAL OF IMMUNOLOGY

Regulatory Effect of 25-hydroxyvitamin D3on Nitric Oxide Production in Activated Microglia

(2014) Jinyoung Hur et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

GCN2 and FGF21 are likely mediators of the protection from cancer, autoimmunity, obesity, and diabetes afforded by vegan diets

(2014) Mark F. McCarty   MEDICAL HYPOTHESES

Hydrogen sulfide attenuates hypoxia-induced neurotoxicity through inhibiting microglial activation

(2014) Qun Zhang et al.   PHARMACOLOGICAL RESEARCH

Anti-Inflammatory Effects of α-Galactosylceramide Analogs in Activated Microglia: Involvement of the p38 MAPK Signaling Pathway

(2014) Yeon-Hui Jeong et al.   PLoS One

Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease

(2014) Michael A. Schwarzschild et al.   JAMA Neurology

Thioredoxin 1 Is Essential for Sodium Sulfide–Mediated Cardioprotection in the Setting of Heart Failure

(2013) Chad K. Nicholson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Comparison of (−)-Epigallocatechin-3-O-gallate (EGCG) and O-Methyl EGCG Bioavailability in Rats

(2013) Yukihiro Oritani et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease

(2013) Hui Qi et al.   Geriatrics & Gerontology International

Inhibition of RAGE signaling through the intracellular delivery of inhibitor peptides by PEI cationization

(2013) ENDY WIDYA PUTRANTO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The Redox Biochemistry of Protein Sulfenylation and Sulfinylation

(2013) Mauro Lo Conte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant effect of Spirulina (Arthrospira) maxima in a neurotoxic model caused by 6-OHDA in the rat striatum

(2013) J. C. Tobón-Velasco et al.   JOURNAL OF NEURAL TRANSMISSION

A further update on the role of excitotoxicity in the pathogenesis of Parkinson’s disease

(2013) Giulia Ambrosi et al.   JOURNAL OF NEURAL TRANSMISSION

Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies

(2013) Stefan Schildknecht et al.   JOURNAL OF NEUROCHEMISTRY

ATF4 Protects Against Neuronal Death in Cellular Parkinson's Disease Models by Maintaining Levels of Parkin

(2013) X. Sun et al.   JOURNAL OF NEUROSCIENCE

Astaxanthin Suppresses MPP+-Induced Oxidative Damage in PC12 Cells through a Sp1/NR1 Signaling Pathway

(2013) Qinyong Ye et al.   Marine Drugs

Does Restraining Nitric Oxide Biosynthesis Rescue from Toxins-Induced Parkinsonism and Sporadic Parkinson's Disease?

(2013) Satya Prakash Gupta et al.   MOLECULAR NEUROBIOLOGY

Deregulation of calcium homeostasis mediates secreted α–synuclein-induced neurotoxicity

(2013) Katerina Melachroinou et al.   NEUROBIOLOGY OF AGING

Dietary fat intake, pesticide use, and Parkinson's disease

(2013) Freya Kamel et al.   PARKINSONISM & RELATED DISORDERS

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

(2013) G. Curtale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease

(2013) Eleftheria K. Pissadaki et al.   Frontiers in Computational Neuroscience

Sulfhydration mediates neuroprotective actions of parkin

(2013) M. Scott Vandiver et al.   Nature Communications

Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease

(2013) Carmen Noelker et al.   Scientific Reports

Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress

(2012) Jing Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway

(2012) Kinnari Sathe et al.   BRAIN

Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury

(2012) T Katome et al.   CELL DEATH AND DIFFERENTIATION

Docosahexaenoic acid provides protective mechanism in bilaterally MPTP-lesioned rat model of Parkinson's disease

(2012) Gulay Hacioglu et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Exendin-4 inhibits iNOS expression at the protein level in LPS-stimulated Raw264.7 macrophage by the activation of cAMP/PKA pathway

(2012) Seo-Yoon Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Vitamin D Inhibits Monocyte/Macrophage Proinflammatory Cytokine Production by Targeting MAPK Phosphatase-1

(2012) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Microglial Activation and Antioxidant Responses Induced by the Parkinson’s Disease Protein α-Synuclein

(2012) Dawn Béraud et al.   Journal of Neuroimmune Pharmacology

Scavenging Capacity of Marine Carotenoids against Reactive Oxygen and Nitrogen Species in a Membrane-Mimicking System

(2012) Eliseu Rodrigues et al.   Marine Drugs

Habitual intake of dietary flavonoids and risk of Parkinson disease

(2012) X. Gao et al.   NEUROLOGY

A Spirulina-Enhanced Diet Provides Neuroprotection in an α-Synuclein Model of Parkinson's Disease

(2012) Mibel M. Pabon et al.   PLoS One

A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease

(2012) Feng-Jiao Li et al.   TheScientificWorldJOURNAL

Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins

(2011) Zenon Grabarek   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity

(2011) Dan Zhang et al.   Journal of Neuroinflammation

Parkin-Mediated Protection of Dopaminergic Neurons in a Chronic MPTP-Minipump Mouse Model of Parkinson Disease

(2011) Toru Yasuda et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

(2011) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

Dietary intake of metals and risk of Parkinson's disease: A case-control study in Japan

(2011) Yoshihiro Miyake et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The influence and the mechanism of docosahexaenoic acid on a mouse model of Parkinson’s disease

(2011) Ozlem Ozsoy et al.   NEUROCHEMISTRY INTERNATIONAL

Pilot dietary study with normoproteic protein-redistributed plant-food diet and motor performance in patients with Parkinson's disease

(2011) Luciana Baroni et al.   NUTRITIONAL NEUROSCIENCE

Intake of Japanese and Chinese teas reduces risk of Parkinson’s disease

(2011) Keiko Tanaka et al.   PARKINSONISM & RELATED DISORDERS

Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease

(2011) Dawn Béraud et al.   PARKINSONISM & RELATED DISORDERS

TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding

(2011) Masakiyo Sakaguchi et al.   PLoS One

Key Modulatory Role of Presynaptic Adenosine A2AReceptors in Cortical Neurotransmission to the Striatal Direct Pathway

(2011) César Quiroz et al.   TheScientificWorldJOURNAL

Acute effect of milk on serum urate concentrations: a randomised controlled crossover trial

(2010) N. Dalbeth et al.   ANNALS OF THE RHEUMATIC DISEASES

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

(2010) L Bouman et al.   CELL DEATH AND DIFFERENTIATION

Polyamine patterns in the cerebrospinal fluid of patients with Parkinson's disease and multiple system atrophy

(2010) Man-Jeong Paik et al.   CLINICA CHIMICA ACTA

MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits

(2010) Antonio Recchiuti et al.   FASEB JOURNAL

Astaxanthin protects against MPTP/MPP+-induced mitochondrial dysfunction and ROS production in vivo and in vitro

(2010) Dae-Hee Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease

(2010) Shankar J. Chinta et al.   FREE RADICAL RESEARCH

Antihypertensive Effect of Benifuuki Tea ContainingO-Methylated EGCG

(2010) Ikuko Kurita et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of inducible nitric oxide synthase expression and cell death by (−)-epigallocatechin-3-gallate, a green tea catechin, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease

(2010) Ji Seon Kim et al.   JOURNAL OF CLINICAL NEUROSCIENCE

TLR4 Signaling Inhibitory Pathway Induced by Green Tea Polyphenol Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor

(2010) E. Hong Byun et al.   JOURNAL OF IMMUNOLOGY

Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide

(2010) Izumi Kaji et al.   JOURNAL OF MOLECULAR HISTOLOGY

Low-protein and protein-redistribution diets for Parkinson's disease patients with motor fluctuations: A systematic review

(2010) Emanuele Cereda et al.   MOVEMENT DISORDERS

Low Dosage of Rasagiline and Epigallocatechin Gallate Synergistically Restored the Nigrostriatal Axis in MPTP-Induced Parkinsonism

(2010) Lydia Reznichenko et al.   Neurodegenerative Diseases

Caffeine attenuates lipopolysaccharide-induced neuroinflammation

(2010) Holly M. Brothers et al.   NEUROSCIENCE LETTERS

Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells

(2009) Shyamali Basuroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Serum uric acid levels in patients with Parkinson's disease: Their relationship to treatment and disease duration

(2009) Elisabeth Andreadou et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

The Treatment of Multiple Sclerosis with Inosine

(2009) Clyde E. Markowitz et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Effects of epigallocatechin gallate on rotenone-injured murine brain cultures

(2009) Rudolf Moldzio et al.   JOURNAL OF NEURAL TRANSMISSION

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling

(2008) Saurabh Jha et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

(2008) Seetal Dodd et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells

(2008) Yasutaka Ikeda et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation and Oxidation/Nitration of  -Synuclein Linked to Dopaminergic Neurodegeneration

(2008) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy

(2008) Mark F. McCarty et al.   MEDICAL HYPOTHESES

Uric acid in Parkinson's disease

(2008) Ilana Schlesinger et al.   MOVEMENT DISORDERS

Targeting reactive oxygen species, reactive nitrogen species and inflammation in MPTP neurotoxicity and Parkinson’s disease

(2008) Hironori Yokoyama et al.   NEUROLOGICAL SCIENCES

Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease

(2008) Mehmet Cansev et al.   NEUROSCIENCE RESEARCH

Complex I deficiency in Parkinson's disease frontal cortex

(2007) W. Davis Parker et al.   BRAIN RESEARCH