Activation of Glucagon-Like Peptide-1 Receptor Promotes Neuroprotection in Experimental Autoimmune Encephalomyelitis by Reducing Neuroinflammatory Responses

Exendin-4 Inhibits Matrix Metalloproteinase-9 Activation and Reduces Infarct Growth After Focal Cerebral Ischemia in Hyperglycemic Mice

(2016) Takuma Kuroki et al.   STROKE

Selective modulation of microglia polarization to M2 phenotype for stroke treatment

(2015) Cong-Yuan Xia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain

(2015) Simon C. Cork et al.   Molecular Metabolism

Neuroprotective Effect of 6-Paradol in Focal Cerebral Ischemia Involves the Attenuation of Neuroinflammatory Responses in Activated Microglia

(2015) Bhakta Prasad Gaire et al.   PLoS One

Activation of Spinal Glucagon-Like Peptide-1 Receptors Specifically Suppresses Pain Hypersensitivity

(2014) N. Gong et al.   JOURNAL OF NEUROSCIENCE

Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents

(2014) Takashi Iwai et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Exendin-4 Reduces Ischemic Brain Injury in Normal and Aged Type 2 Diabetic Mice and Promotes Microglial M2 Polarization

(2014) Vladimer Darsalia et al.   PLoS One

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: Targets for disease modification?

(2014) Fares Bassil et al.   PROGRESS IN NEUROBIOLOGY

Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes

(2014) Wing Yip Tam et al.   Scientific Reports

Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

(2013) Christian Hölscher   JOURNAL OF ENDOCRINOLOGY

Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF- B Signaling

(2013) Q.-Q. Yin et al.   JOURNAL OF IMMUNOLOGY

Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice

(2013) Jessica M. Crain et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation

(2013) Alessandra di Penta et al.   PLoS One

Exendin-4 Ameliorates Traumatic Brain Injury-Induced Cognitive Impairment in Rats

(2013) Katharine Eakin et al.   PLoS One

Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology

(2013) Conor Mc Guire et al.   TRENDS IN MOLECULAR MEDICINE

Retracted: Exendin-4 reverts behavioural and neurochemical dysfunction in a pre-motor rodent model of Parkinson's disease with noradrenergic deficit

(2012) N Rampersaud et al.   BRITISH JOURNAL OF PHARMACOLOGY

The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride

(2012) V. Darsalia et al.   DIABETES

The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain

(2012) Vadivel Parthsarathy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

GLP-1 secretion by microglial cells and decreased CNS expression in obesity

(2012) Camilla Kappe et al.   Journal of Neuroinflammation

Exendin-4 Improves Steatohepatitis by Increasing Sirt1 Expression in High-Fat Diet-Induced Obese C57BL/6J Mice

(2012) Jinmi Lee et al.   PLoS One

Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis

(2012) Yazhou Li et al.   PLoS One

Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer’s disease by exendin-4

(2011) Song Chen et al.   AGE

Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats

(2011) Vladimer Darsalia et al.   CLINICAL SCIENCE

Beneficial Effects of Exendin-4 on Experimental Polyneuropathy in Diabetic Mice

(2011) T. Himeno et al.   DIABETES

Exendin-4, a Glucagon-Like Peptide-1 Receptor Agonist, Provides Neuroprotection in Mice Transient Focal Cerebral Ischemia

(2011) Shinichiro Teramoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Fingolimod modulates microglial activation to augment markers of remyelination

(2011) Samuel J Jackson et al.   Journal of Neuroinflammation

The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease

(2011) P. L. McClean et al.   JOURNAL OF NEUROSCIENCE

Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia

(2011) Choong Hyun Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Amelioration of Experimental Autoimmune Encephalomyelitis by Plumbagin through Down-Regulation of JAK-STAT and NF-κB Signaling Pathways

(2011) Yan Jia et al.   PLoS One

Reversible neural stem cell niche dysfunction in a model of multiple sclerosis

(2010) Stine Rasmussen et al.   ANNALS OF NEUROLOGY

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

(2010) J. W. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease

(2009) Sehee Kim et al.   JOURNAL OF ENDOCRINOLOGY

Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system

(2009) Alison Hamilton et al.   NEUROREPORT

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

(2009) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FTY720 Rescue Therapy in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis: Expression of Central Nervous System Genes and Reversal of Blood-Brain-Barrier Damage

(2008) Carolyn A. Foster et al.   BRAIN PATHOLOGY

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

(2008) May H. Han et al.   NATURE

Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-β peptide (1–42)

(2008) Zhenxia Qin et al.   NEUROSCIENCE LETTERS