Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment

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Title
Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment
Authors
Keywords
Myeloperoxidase, Reactive oxygen species, Synucleinopathies, Nitration, Carbamylation, Hypochlorous acid, MPO-H, 2, O, 2, -chloride system, Parkinson's disease, Alpha synuclein, Hippocampus CA2 region, Dementia with lewy bodies, ER stress, Unfolded protein response
Journal
FREE RADICAL BIOLOGY AND MEDICINE
Volume 141, Issue -, Pages 115-140
Publisher
Elsevier BV
Online
2019-06-06
DOI
10.1016/j.freeradbiomed.2019.05.033

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