Toll-Like Receptor Expression in the Blood and Brain of Patients and a Mouse Model of Parkinson's Disease

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

(2014) T. Raj et al.   SCIENCE

Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease

(2013) Natalja Funk et al.   MOVEMENT DISORDERS

Screening of Toll-Like Receptors Expression in Multiple System Atrophy Brains

(2013) Tomasz Brudek et al.   NEUROCHEMICAL RESEARCH

Elevated Alpha-Synuclein Impairs Innate Immune Cell Function and Provides a Potential Peripheral Biomarker for Parkinson's Disease

(2013) Shyra J. Gardai et al.   PLoS One

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

(2013) Changyoun Kim et al.   Nature Communications

MyD88 deficiency results in both cognitive and motor impairments in mice

(2012) J. Drouin-Ouellet et al.   BRAIN BEHAVIOR AND IMMUNITY

Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein

(2012) Melanie B. Watson et al.   EXPERIMENTAL NEUROLOGY

Reduced T helper and B lymphocytes in Parkinson's disease

(2012) Claire H. Stevens et al.   JOURNAL OF NEUROIMMUNOLOGY

A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice

(2012) Marie-Francoise Chesselet et al.   Neurotherapeutics

Inflammation and neurodegeneration: the story ‘retolled’

(2012) Janelle Drouin-Ouellet et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons

(2011) Nadia Stefanova et al.   AMERICAN JOURNAL OF PATHOLOGY

The critical role of the MyD88-dependent pathway in non-CNS MPTP-mediated toxicity

(2011) M. Côté et al.   BRAIN BEHAVIOR AND IMMUNITY

Circadian dysfunction in a mouse model of Parkinson's disease

(2011) Takashi Kudo et al.   EXPERIMENTAL NEUROLOGY

Effects of peripheral lymphocyte subpopulations and the clinical correlation with Parkinson's disease

(2011) Fumitoshi Niwa et al.   Geriatrics & Gerontology International

The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration

(2011) Janelle Drouin-Ouellet et al.   Journal of Neuroinflammation

Accumulation of Transactive Response DNA Binding Protein 43 in Mild Cognitive Impairment and Alzheimer Disease

(2011) Cyntia Tremblay et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Modelling of Parkinson's disease in mice

(2011) Marie-Françoise Chesselet et al.   LANCET NEUROLOGY

Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism

(2011) F. Ros-Bernal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of a TIR-less Splice Variant of TRIF Reveals an Unexpected Mechanism of TLR3-mediated Signaling

(2010) Ke-Jun Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1

(2010) E.-J. Lee et al.   JOURNAL OF IMMUNOLOGY

Circulating interleukin-10 and interleukin-12 in Parkinson’s disease

(2009) M. Rentzos et al.   ACTA NEUROLOGICA SCANDINAVICA

Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation

(2009) M. Lalancette-Hébert et al.   BRAIN

A central role for monocytes in Toll-like receptor-mediated activation of the vasculature

(2009) Jon R. Ward et al.   IMMUNOLOGY

TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients

(2009) M. Jagannathan et al.   JOURNAL OF IMMUNOLOGY

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar A -Stimulated Microglial Activation

(2009) E. G. Reed-Geaghan et al.   JOURNAL OF NEUROSCIENCE

Expression of TLR4 and CD14 in the Central Nervous System (CNS) in a MPTP Mouse Model of Parkinson's-Like Disease

(2008) Maria Antonietta Panaro et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease

(2008) Shaji Theodore et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Synuclein activates microglia in a model of Parkinson's disease

(2007) Xiaomin Su et al.   NEUROBIOLOGY OF AGING

Screening of innate immune receptors in neurodegenerative diseases: A similar pattern

(2007) Maryse Letiembre et al.   NEUROBIOLOGY OF AGING