Fluctuations of Histone Chemical Modifications in Breast, Prostate, and Colorectal Cancer: An Implication of Phytochemicals as Defenders of Chromatin Equilibrium

From Genotype to Phenotype: Through Chromatin

(2019) Julia Romanowska et al.   Genes

Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

(2019) Rocio G Urdinguio et al.   NUCLEIC ACIDS RESEARCH

Dietary Phytochemicals Targeting Cancer Stem Cells

(2019) Alena Liskova et al.   MOLECULES

Green tea-induced epigenetic reactivation of tissue inhibitor of matrix metalloproteinase-3 suppresses prostate cancer progression through histone-modifying enzymes

(2019) Gauri Deb et al.   MOLECULAR CARCINOGENESIS

Controlling metastatic cancer: the role of phytochemicals in cell signaling

(2019) Andrea Kapinova et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Acetylation & Co: an expanding repertoire of histone acylations regulates chromatin and transcription

(2019) Claire E. Barnes et al.   Essays in Biochemistry

Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma in Vivo and in Vitro

(2019) Kubatka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of dietary phytochemicals in the carcinogenesis via the modulation of miRNA expression

(2019) Marek Samec et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Contribution of BRCA1 5382insC mutation in triple negative breast cancer in Tunisia

(2019) Wijden Mahfoudh et al.   Journal of Translational Medicine

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination

(2019) Marco Igor Valencia-Sánchez et al.   MOLECULAR CELL

Epigenetic Gene Regulation by Dietary Compounds in Cancer Prevention

(2019) McKale Montgomery et al.   Advances in Nutrition

ADP-ribosylation signalling and human disease

(2019) Luca Palazzo et al.   Open Biology

Resveratrol modulates epigenetic regulators of promoter histone methylation and acetylation that restores BRCA1, p53, p21 CIP1 in human breast cancer cell lines

(2019) Biji Chatterjee et al.   BIOFACTORS

Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer

(2019) Vladislav Korobeynikov et al.   BREAST CANCER RESEARCH AND TREATMENT

Natural products: An upcoming therapeutic approach to cancer

(2019) Sayanta Dutta et al.   FOOD AND CHEMICAL TOXICOLOGY

Inositol phosphates and core subunits of the Sin3L/Rpd3L histone deacetylase (HDAC) complex up-regulate deacetylase activity

(2019) Ryan Dale Marcum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential Effects

(2019) Faiz-ul Hassan et al.   Frontiers in Genetics

DNA Methylation Status in Cancer Disease: Modulations by Plant-Derived Natural Compounds and Dietary Interventions

(2019) Karin Jasek et al.   Biomolecules

Paederia foetida induces anticancer activity by modulating chromatin modification enzymes and altering pro-inflammatory cytokine gene expression in human prostate cancer cells

(2019) Nibedita Pradhan et al.   FOOD AND CHEMICAL TOXICOLOGY

Combinatorial Epigenetics Impact of Polyphenols and Phytochemicals in Cancer Prevention and Therapy

(2019) Arora et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNAs and Epigenetics Strategies to Reverse Breast Cancer

(2019) Mohammad Mijanur Rahman et al.   Cells

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

(2018) Yuanxin Xi et al.   BMC GENOMICS

Withaferin A and sulforaphane regulate breast cancer cell cycle progression through epigenetic mechanisms

(2018) Kendra J. Royston et al.   EXPERIMENTAL CELL RESEARCH

Curcumin suppressed the prostate cancer by inhibiting JNK pathways via epigenetic regulation

(2018) Wanli Zhao et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs

(2018) Adaobi Okonkwo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Interplay between long non-coding RNAs and epigenetic machinery: emerging targets in cancer?

(2018) David J. Hanly et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Transcriptomic and epigenetic analysis of breast cancer stem cells

(2018) Guochao Li et al.   Epigenomics

Tricaproin Isolated From Simarouba glauca Inhibits the Growth of Human Colorectal Carcinoma Cell Lines by Targeting Class-1 Histone Deacetylases

(2018) Asha Jose et al.   Frontiers in Pharmacology

Premenopausal breast cancer: potential clinical utility of a multi-omics based machine learning approach for patient stratification

(2018) Holger Fröhlich et al.   EPMA Journal

Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic–Mediating Machinery

(2018) Yifeng Gao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The dietary flavone luteolin epigenetically activates the Nrf2 pathway and blocks cell transformation in human colorectal cancer HCT116 cells

(2018) Qian Zuo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Interplay of Histone Marks with Serine ADP-Ribosylation

(2018) Edward Bartlett et al.   Cell Reports

Association Between BRCA Status and Triple-Negative Breast Cancer: A Meta-Analysis

(2018) Haixia Chen et al.   Frontiers in Pharmacology

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

(2018) A. Kapinova et al.   Environmental Health and Preventive Medicine

Ubiquitin Regulation: The Histone Modifying Enzyme′s Story

(2018) Jianlin Wang et al.   Cells

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Synergistic anticancer action of quercetin and curcumin against triple-negative breast cancer cell lines

(2018) Sai Kundur et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prognostic and Predictive Epigenetic Biomarkers in Oncology

(2018) Katarzyna Kamińska et al.   Molecular Diagnosis & Therapy

MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20

(2018) Penelope D. Ruiz et al.   Nature Communications

Improved Preventive Effects of Combined Bioactive Compounds Present in Different Blueberry Varieties as Compared to Single Phytochemicals

(2018) Simone van Breda et al.   Nutrients

Evidence of Some Natural Products with Antigenotoxic Effects. Part 2: Plants, Vegetables, and Natural Resin

(2018) David López-Romero et al.   Nutrients

Flavonoids in Cancer and Apoptosis

(2018) Mariam Abotaleb et al.   Cancers

Plant natural modulators in breast cancer prevention: status quo and future perspectives reinforced by predictive, preventive, and personalized medical approach

(2018) Sona Uramova et al.   EPMA Journal

A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells

(2017) Kendra Royston et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma

(2017) Peter Kubatka et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The impact of cruciferous vegetable isothiocyanates on histone acetylation and histone phosphorylation in bladder cancer

(2017) Besma Abbaoui et al.   Journal of Proteomics

The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage

(2017) Kelly R. Karch et al.   Molecular BioSystems

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication

(2017) Wan-Shan Yang et al.   PLoS Pathogens

RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

(2017) Whitney L Johnson et al.   eLife

SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites

(2017) Atsuhiko Fukuto et al.   Nucleus

SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites

(2017) Atsuhiko Fukuto et al.   Nucleus

Circulating Nucleosomes and Nucleosome Modifications as Biomarkers in Cancer

(2017) Peter McAnena et al.   Cancers

Post-Translational Modification of Human Histone by Wide Tolerance of Acetylation

(2017) Cuiling Li et al.   Cells

Postmenopausal breast cancer: European challenge and innovative concepts

(2017) Ivica Smokovski et al.   EPMA Journal

Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

(2016) Alessandra Bosutti et al.   Anti-Cancer Agents in Medicinal Chemistry

Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines

(2016) Ata Abbas et al.   Biochemistry and Cell Biology

DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers

(2016) Ching-Yu Yen et al.   CANCER LETTERS

An ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis

(2016) Ishfaq Ahmed et al.   CARCINOGENESIS

Editorial (Thematic Issue: Anticancer Natural Compounds: Molecular Mechanisms and Functions. Part I)

(2016) Edward Ratovitski   CURRENT GENOMICS

Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model

(2016) Peter Kubatka et al.   EUROPEAN JOURNAL OF NUTRITION

Differences in survival for patients with familial and sporadic cancer

(2016) Myeongjee Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer

(2016) Sabnam Parbin et al.   Molecular BioSystems

Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1

(2016) Hitoshi Aihara et al.   MOLECULAR CELL

Induction of cell cycle arrest and apoptosis with downregulation of Hsp90 client proteins and histone modification by 4β-hydroxywithanolide E isolated fromPhysalis peruviana

(2016) Eun-Jung Park et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Young Barley Indicates Antitumor Effects in Experimental Breast Cancer In Vivo and In Vitro

(2016) Peter Kubatka et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

An overview on the role of dietary phenolics for the treatment of cancers

(2016) Preethi G. Anantharaju et al.   Nutrition Journal

Epigenetic gene regulation by histone demethylases: emerging role in oncogenesis and inflammation

(2016) MK Kang et al.   ORAL DISEASES

The clinical phenotype of hereditary versus sporadic prostate cancer: HPC definition revisited

(2016) Ruben G. Cremers et al.   PROSTATE

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

(2016) Eswar Shankar et al.   SEMINARS IN CANCER BIOLOGY

Histone H3 lysine 23 acetylation is associated with oncogene TRIM24 expression and a poor prognosis in breast cancer

(2016) Li Ma et al.   TUMOR BIOLOGY

Histone Modifications and Cancer

(2016) James E. Audia et al.   Cold Spring Harbor Perspectives in Biology

Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes

(2016) Terri L. Messier et al.   Oncotarget

Targeting histone methylation for colorectal cancer

(2016) Tao Huang et al.   Therapeutic Advances in Gastroenterology

Medicine in the early twenty-first century: paradigm and anticipation - EPMA position paper 2016

(2016) Olga Golubnitschaja et al.   EPMA Journal

Molecular Basis for Histone Acetyltransferase Regulation by Binding Partners, Associated Domains, and Autoacetylation

(2015) Cheryl E. McCullough et al.   ACS Chemical Biology

Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1

(2015) Yue Guo et al.   BIOCHEMICAL PHARMACOLOGY

Cancer Therapy with Phytochemicals: Present and Future Perspectives

(2015) Muobarak J. Tuorkey   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

The role of epigenetics in personalized medicine: challenges and opportunities

(2015) Mahmood Rasool et al.   BMC Medical Genomics

Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy

(2015) L. L. Atwell et al.   Cancer Prevention Research

Histone methylation modifiers in cellular signaling pathways

(2015) Hunain Alam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ADP-Ribosyltransferases and Poly ADP-Ribosylation

(2015) Chao Liu et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Histone ubiquitylation and its roles in transcription and DNA damage response

(2015) Rithy Meas et al.   DNA REPAIR

Histone demethylases in chromatin biology and beyond

(2015) E. Dimitrova et al.   EMBO REPORTS

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle

(2015) S. P. Hergeth et al.   EMBO REPORTS

Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer

(2015) Peter Kubatka et al.   EUROPEAN JOURNAL OF NUTRITION

Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations

(2015) Özlem Önder et al.   Expert Review of Proteomics

Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis

(2015) Hyung Seok Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time

(2015) Rick van Nuland et al.   MOLECULAR & CELLULAR PROTEOMICS

Antineoplastic effects of Chlorella pyrenoidosa in the breast cancer model

(2015) Peter Kubatka et al.   NUTRITION

Curcumin Reactivates Silenced Tumor Suppressor Gene RARβ by Reducing DNA Methylation

(2015) Apei Jiang et al.   PHYTOTHERAPY RESEARCH

The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis

(2015) Xiao-Jian Sun et al.   Frontiers in Oncology

Actionable pharmacogenetic markers for prediction and prognosis in breast cancer

(2015) Keith Sacco et al.   EPMA Journal

Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70–Bax interaction in prostate cancer

(2014) Sanjeev Shukla et al.   APOPTOSIS

Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer

(2014) Anne Benard et al.   BMC CANCER

Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case–control EpiGEICAM study

(2014) A Castelló et al.   BRITISH JOURNAL OF CANCER

Epigenetic targeting in pancreatic cancer

(2014) Jasmijn G.M. van Kampen et al.   CANCER TREATMENT REVIEWS

Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer

(2014) Anne Benard et al.   HISTOPATHOLOGY

Sumoylated Human Histone H4 Prevents Chromatin Compaction by Inhibiting Long-range Internucleosomal Interactions

(2014) Abhinav Dhall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes

(2014) A. L. Nguyen et al.   JOURNAL OF CELL SCIENCE

A Comprehensive View of the Epigenetic Landscape. Part II: Histone Post-translational Modification, Nucleosome Level, and Chromatin Regulation by ncRNAs

(2014) Anna Sadakierska-Chudy et al.   NEUROTOXICITY RESEARCH

Methylation and miRNA Effects of Resveratrol on Mammary Tumors vs. Normal Tissue

(2014) Wenyi Qin et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

HDAC4: mechanism of regulation and biological functions

(2014) Zhengke Wang et al.   Epigenomics

Specific Phosphorylation of Histone Demethylase KDM3A Determines Target Gene Expression in Response to Heat Shock

(2014) Mo-bin Cheng et al.   PLOS BIOLOGY

Assay Development for Histone Methyltransferases

(2013) Kurumi Y. Horiuchi et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation

(2013) Chengyue Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motilityin vitroand drives tumor formationin vivo

(2013) Yuhki Yokoyama et al.   CANCER SCIENCE

Molecular Pathways: Environmental Estrogens Activate Nongenomic Signaling to Developmentally Reprogram the Epigenome

(2013) R. L. Y. Wong et al.   CLINICAL CANCER RESEARCH

Expression of Acetylated and Dimethylated Histone H3 in Colorectal Cancer

(2013) Toshio Hashimoto et al.   DIGESTIVE SURGERY

Assessment of Aurora a Kinase Expression in Breast Cancer: A Tool for Early Diagnosis?

(2013) Imen Ferchichi et al.   DISEASE MARKERS

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

(2013) Praveen Rajendran et al.   Epigenetics

Compound K, a metabolite of ginseng saponin, inhibits colorectal cancer cell growth and induces apoptosis through inhibition of histone deacetylase activity

(2013) KYOUNG AH KANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor

(2013) Denise A. Yardley et al.   JOURNAL OF CLINICAL ONCOLOGY

Sites of Acetylation on Newly Synthesized Histone H4 Are Required for Chromatin Assembly and DNA Damage Response Signaling

(2013) Zhongqi Ge et al.   MOLECULAR AND CELLULAR BIOLOGY

H3R42me2a is a histone modification with positive transcriptional effects

(2013) F. Casadio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase

(2012) Marco Gatti et al.   CELL CYCLE

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growthin vivo

(2012) Samir Attoub et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Histone ADP-Ribosylation Facilitates Gene Transcription by Directly Remodeling Nucleosomes

(2012) R. Martinez-Zamudio et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Effects ofThymus serpyllumExtract on Cell Proliferation, Apoptosis and Epigenetic Events in Human Breast Cancer Cells

(2012) Emir Bozkurt et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Tanshinones Inhibit the Growth of Breast Cancer Cells through Epigenetic Modification of Aurora A Expression and Function

(2012) Yi Gong et al.   PLoS One

Alterations of global histone H4K20 methylation during prostate carcinogenesis

(2012) Turang E Behbahani et al.   BMC Urology

Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity

(2012) Mitsuhiro Endoh et al.   PLoS Genetics

Histone Ubiquitination and Deubiquitination in Transcription, DNA Damage Response, and Cancer

(2012) Jian Cao et al.   Frontiers in Oncology

Thymoquinone: Potential cure for inflammatory disorders and cancer

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Histone tyrosine phosphorylation comes of age

(2011) Rakesh Kumar Singh et al.   Epigenetics

Cross Talk between Ubiquitination and Demethylation

(2011) X. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H3 Lysine 56 Acetylation and the Response to DNA Replication Fork Damage

(2011) H. Wurtele et al.   MOLECULAR AND CELLULAR BIOLOGY

Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: In vitro and in vivo study

(2011) Mitali Pandey et al.   MOLECULAR CARCINOGENESIS

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

(2011) John D. Clarke et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription

(2011) Q Zhang et al.   ONCOGENE

Methylation of H2AR29 is a novel repressive PRMT6 target

(2011) Tanja Waldmann et al.   Epigenetics & Chromatin

Role of histone methylation and demethylation in adipogenesis and obesity

(2011) Masashi Okamura et al.   Organogenesis

Global Levels of Specific Histone Modifications and an Epigenetic Gene Signature Predict Prostate Cancer Progression and Development

(2010) T. Bianco-Miotto et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Reciprocal epigenetic modification of histone H2B occurs in chromatin during apoptosis in vitro and in vivo

(2010) K Ajiro et al.   CELL DEATH AND DIFFERENTIATION

Physalis peruviana Linnaeus, the multiple properties of a highly functional fruit: A review

(2010) Luis A. Puente et al.   FOOD RESEARCH INTERNATIONAL

A crystal lapiferin derived fromFerula vesceritensisinduces apoptosis pathway in MCF-7 breast cancer cells

(2010) Amira M. Gamal-Eldeen et al.   NATURAL PRODUCT RESEARCH

Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation

(2010) D. Bungard et al.   SCIENCE

The Role of Functional Foods, Nutraceuticals, and Food Supplements in Intestinal Health

(2010) Avrelija Cencic et al.   Nutrients

Phase II, two-stage, single-arm trial of the histone deacetylase inhibitor (HDACi) romidepsin in metastatic castration-resistant prostate cancer (CRPC)

(2009) L. R. Molife et al.   ANNALS OF ONCOLOGY

Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer

(2009) Shahana Majid et al.   CANCER

Global Histone Modifications in Breast Cancer Correlate with Tumor Phenotypes, Prognostic Factors, and Patient Outcome

(2009) S. E. Elsheikh et al.   CANCER RESEARCH

BBAP Monoubiquitylates Histone H4 at Lysine 91 and Selectively Modulates the DNA Damage Response

(2009) Qingsheng Yan et al.   MOLECULAR CELL

Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6

(2009) A. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global levels of histone modifications predict prostate cancer recurrence

(2009) Jörg Ellinger et al.   PROSTATE

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

(2008) Yong Lin et al.   CURRENT CANCER DRUG TARGETS

Global Histone H4 Acetylation and HDAC2 Expression in Colon Adenoma and Carcinoma

(2008) Hassan Ashktorab et al.   DIGESTIVE DISEASES AND SCIENCES

Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers

(2008) Yongkun Wei et al.   MOLECULAR CARCINOGENESIS

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE