Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential Effects
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Title
Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential Effects
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-06-04
DOI
10.3389/fgene.2019.00514
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Note: Only part of the references are listed.- Control of metabolism by p53 – Cancer and beyond
- (2018) Christiaan F. Labuschagne et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells
- (2018) Pengfei Su et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling
- (2018) Hongbing Fu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2
- (2018) Sourav Banerjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The functional genomic studies of curcumin
- (2017) Lukasz Huminiecki et al. SEMINARS IN CANCER BIOLOGY
- Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway
- (2017) Cheng Gong et al. OncoTargets and Therapy
- Nano-formulated curcumin accelerates acute wound healing through Dkk-1-mediated fibroblast mobilization and MCP-1-mediated anti-inflammation
- (2017) Xinyi Dai et al. NPG Asia Materials
- Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a
- (2017) Huiqiang Dou et al. Frontiers in Pharmacology
- Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells
- (2017) Aida Rodriguez-Garcia et al. Redox Biology
- Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia
- (2016) Elena Ceccacci et al. BRITISH JOURNAL OF CANCER
- Role of p53 isoforms and aggregations in cancer
- (2016) SeJin Kim et al. MEDICINE
- Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence
- (2016) H Jin et al. Cell Death & Disease
- HDACs and HDAC Inhibitors in Cancer Development and Therapy
- (2016) Yixuan Li et al. Cold Spring Harbor Perspectives in Medicine
- Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer
- (2015) S. Toden et al. Cancer Prevention Research
- Differential expressions of cancer-associated genes and their regulatory miRNAs in colorectal carcinoma
- (2015) Murat Kara et al. GENE
- Curcumin Reactivates Silenced Tumor Suppressor Gene RARβ by Reducing DNA Methylation
- (2015) Apei Jiang et al. PHYTOTHERAPY RESEARCH
- Long Term Effect of Curcumin in Restoration of Tumour Suppressor p53 and Phase-II Antioxidant Enzymes via Activation of Nrf2 Signalling and Modulation of Inflammation in Prevention of Cancer
- (2015) Laxmidhar Das et al. PLoS One
- A preliminary study of the effect of curcumin on the expression of p53 protein in a human multiple myeloma cell line
- (2015) WEI LI et al. Oncology Letters
- Induction of MicroRNA-9 Mediates Cytotoxicity of Curcumin Against SKOV3 Ovarian Cancer Cells
- (2014) Song-Feng Zhao et al. Asian Pacific Journal of Cancer Prevention
- Curcumin exerts inhibitory effects on undifferentiated nasopharyngeal carcinoma by inhibiting the expression ofmiR-125a-5p
- (2014) Wei Gao et al. CLINICAL SCIENCE
- miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2
- (2014) Emanuel Kronski et al. Molecular Oncology
- Curcumin and Dimethoxycurcumin Induced Epigenetic Changes in Leukemia Cells
- (2014) Hazem E. Hassan et al. PHARMACEUTICAL RESEARCH
- Curcumin Modulates miR-19/PTEN/AKT/p53 Axis to Suppress Bisphenol A-induced MCF-7 Breast Cancer Cell Proliferation
- (2014) Xiaoting Li et al. PHYTOTHERAPY RESEARCH
- Curcumin Alleviates Neuropathic Pain by Inhibiting p300/CBP Histone Acetyltransferase Activity-Regulated Expression of BDNF and Cox-2 in a Rat Model
- (2014) Xiaoyan Zhu et al. PLoS One
- Pure curcumin increases the expression of SOCS1 and SOCS3 in myeloproliferative neoplasms through suppressing class Ι histone deacetylases
- (2013) Chi-qi Chen et al. CARCINOGENESIS
- Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor
- (2013) Hideaki Ogiwara et al. CARCINOGENESIS
- Molecular flexibility and the electrostatic moments of curcumin and its derivatives in the active site of p300: A theoretical charge density study
- (2013) B. Devipriya et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation - a novel mechanism suppressing liver fibrosis
- (2013) Jianjian Zheng et al. FEBS Journal
- Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion
- (2013) Shuang Gao et al. FOOD AND CHEMICAL TOXICOLOGY
- Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats
- (2013) Susana González-Reyes et al. Oxidative Medicine and Cellular Longevity
- Neuroprotection by Curcumin in Ischemic Brain Injury Involves the Akt/Nrf2 Pathway
- (2013) Jingxian Wu et al. PLoS One
- Curcumin Down-Regulates DNA Methyltransferase 1 and Plays an Anti-Leukemic Role in Acute Myeloid Leukemia
- (2013) Jianhua Yu et al. PLoS One
- Depletion of Cellular Iron by Curcumin Leads to Alteration in Histone Acetylation and Degradation of Sml1p in Saccharomyces cerevisiae
- (2013) Gajendra Kumar Azad et al. PLoS One
- Curcumin Modulates DNA Methylation in Colorectal Cancer Cells
- (2013) Alexander Link et al. PLoS One
- The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo
- (2013) Chuan He Yang et al. PLoS One
- Renoprotective effect of the antioxidant curcumin: Recent findings
- (2013) Joyce Trujillo et al. Redox Biology
- DNA Methylation Does Not Stably Lock Gene Expression but Instead Serves as a Molecular Mark for Gene Silencing Memory
- (2012) N. J.- M. Raynal et al. CANCER RESEARCH
- Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line
- (2012) Gaurav Parashar et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Reactivation of RASSF1A in Breast Cancer Cells by Curcumin
- (2012) Liping Du et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells
- (2011) Limin Shu et al. AAPS Journal
- Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation
- (2011) Tin Oo Khor et al. BIOCHEMICAL PHARMACOLOGY
- Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo
- (2011) Seung Joon Lee et al. BMC CANCER
- Amelioration of renal ischaemia-reperfusion injury by liposomal delivery of curcumin to renal tubular epithelial and antigen-presenting cells
- (2011) NM Rogers et al. BRITISH JOURNAL OF PHARMACOLOGY
- Curcumin Modulates MicroRNA-203-Mediated Regulation of the Src-Akt Axis in Bladder Cancer
- (2011) S. Saini et al. Cancer Prevention Research
- Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
- (2011) B. Bao et al. CANCER RESEARCH
- Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines
- (2011) He-Ping Yang Molecular Medicine Reports
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- (2011) Abdurazzag Abusnina et al. MOLECULAR NUTRITION & FOOD RESEARCH
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- (2011) Vivian Soetikno et al. Nutrition & Metabolism
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- (2010) Jian Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibiting NF-κB activation by small molecules as a therapeutic strategy
- (2010) Subash C. Gupta et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer
- (2010) Giridhar Mudduluru et al. BIOSCIENCE REPORTS
- Development of curcumin as an epigenetic agent
- (2010) Siqing Fu et al. CANCER
- Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
- (2010) Mathilde Bayet-Robert et al. CANCER BIOLOGY & THERAPY
- Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF
- (2010) Shadan Ali et al. CANCER RESEARCH
- The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy
- (2010) T. Jiang et al. DIABETES
- The NRF2–heme oxygenase-1 system modulates cyclosporin A-induced epithelial–mesenchymal transition and renal fibrosis
- (2010) Dong-ha Shin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Curcumin-induced histone acetylation in malignant hematologic cells
- (2010) Junbin Hu et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin
- (2010) Jung-Mi Yun et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach
- (2010) Jose L. Medina-Franco et al. MOLECULAR DIVERSITY
- A histone code for DNA repair
- (2010) Ralph Scully NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulation of microRNAs by Natural Agents: An Emerging Field in Chemoprevention and Chemotherapy Research
- (2010) Yiwei Li et al. PHARMACEUTICAL RESEARCH
- Effect of Curcumin on Nuclear Factor κB Signaling Pathways in Human Chronic Myelogenous K562 Leukemia Cells
- (2009) Simone Reuter et al. Annals of the New York Academy of Sciences
- Suppression of Interleukin 6 and 8 Production in Head and Neck Cancer Cells With Curcumin via Inhibition of Iκβ Kinase
- (2009) Alen N. Cohen et al. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
- Curcumin, a Potential Inhibitor of Up-regulation of TNF-alpha and IL-6 Induced by Palmitate in 3T3-L1 Adipocytes through NF-kappaB and JNK Pathway
- (2009) Shao-Ling WANG et al. BIOMEDICAL AND ENVIRONMENTAL SCIENCES
- Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
- (2009) Gamze Bora-Tatar et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation
- (2009) Dirk Kuck et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Modes of p53 Regulation
- (2009) Jan-Philipp Kruse et al. CELL
- Curcumin Binding to DNA and RNA
- (2009) Shohreh Nafisi et al. DNA AND CELL BIOLOGY
- Molecular Targets of Nutraceuticals Derived from Dietary Spices: Potential Role in Suppression of Inflammation and Tumorigenesis
- (2009) Bharat B. Aggarwal et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice
- (2009) Manchang Liu et al. KIDNEY INTERNATIONAL
- Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells
- (2009) Jie Yang et al. MEDICAL ONCOLOGY
- Many roads to maturity: microRNA biogenesis pathways and their regulation
- (2009) Julia Winter et al. NATURE CELL BIOLOGY
- Causes and consequences of microRNA dysregulation in cancer
- (2009) Carlo M. Croce NATURE REVIEWS GENETICS
- Clinical Outcomes and Correlates of TP53 Mutations and Cancer
- (2009) A. I. Robles et al. Cold Spring Harbor Perspectives in Biology
- DNA hypomethylation in cancer cells
- (2009) Melanie Ehrlich Epigenomics
- Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-κB
- (2008) Parvaneh Rafiee et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Curcumin Restores Corticosteroid Function in Monocytes Exposed to Oxidants by Maintaining HDAC2
- (2008) Koremu K. Meja et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Role of HDAC2 in the Pathophysiology of COPD
- (2008) Peter J. Barnes Annual Review of Physiology
- Curcumin is a potent DNA hypomethylation agent
- (2008) Zhongfa Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cathepsin L Proteolytically Processes Histone H3 During Mouse Embryonic Stem Cell Differentiation
- (2008) Elizabeth M. Duncan et al. CELL
- Curcumin: From ancient medicine to current clinical trials
- (2008) H. Hatcher et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells
- (2008) Faisal Thayyullathil et al. FREE RADICAL BIOLOGY AND MEDICINE
- Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-κB and STAT3 pathways in Hodgkin's lymphoma cells
- (2008) Gerardo G. Mackenzie et al. INTERNATIONAL JOURNAL OF CANCER
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats
- (2008) Tatsuya Morimoto et al. JOURNAL OF CLINICAL INVESTIGATION
- Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
- (2008) M. Sun et al. MOLECULAR CANCER THERAPEUTICS
- Dietary Components Impact Histone Modifications and Cancer Risk
- (2008) Cindy D. Davis et al. NUTRITION REVIEWS
- Evidence for dietary regulation of microRNA expression in cancer cells
- (2008) Cindy D Davis et al. NUTRITION REVIEWS
- Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets
- (2008) Bharat B. Aggarwal et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Recent advances in the investigation of curcuminoids
- (2008) Hideji Itokawa et al. Chinese Medicine
- Role of curcumin in health and disease
- (2008) Leelavinothan Pari et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Regulation of protein turnover by acetyltransferases and deacetylases
- (2007) Karin Sadoul et al. BIOCHIMIE
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