Resveratrol modulates epigenetic regulators of promoter histone methylation and acetylation that restores BRCA1, p53, p21 CIP1 in human breast cancer cell lines

Targeting Epigenetics in Cancer

(2018) Richard L. Bennett et al.   Annual Review of Pharmacology and Toxicology

Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics

(2018) Ibraheem Ali et al.   CHEMICAL REVIEWS

Protein Arginine Methyltransferase 5 (PRMT5) as an Anticancer Target and Its Inhibitor Discovery

(2018) Yuanxiang Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enhancer of zeste homolog 2 (EZH2) inhibitors

(2018) Nitya Gulati et al.   LEUKEMIA & LYMPHOMA

The persistent organochlorine pesticide endosulfan modulates multiple epigenetic regulators with oncogenic potential in MCF-7 cells

(2018) Krishna Ghosh et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways

(2018) Takahiro Ito et al.   Cell Reports

Curcumin-mediated demethylation of the proximal promoter CpG island enhances the KLF4 recruitment that leads to increased expression of p21Cip1 in vitro

(2018) Biji Chatterjee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells

(2018) Biji Chatterjee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Targeting protein arginine methyltransferase 5 in disease

(2017) André Richters   Future Medicinal Chemistry

Histone Deacetylase Inhibitors as Anticancer Drugs

(2017) Tomas Eckschlager et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target

(2017) Danielly Ferraz da Costa et al.   MOLECULES

The Effect of Resveratrol on Cell Viability in the Burkitt’s Lymphoma Cell Line Ramos

(2017) Paola Jara et al.   MOLECULES

Epigenetic Regulatory Mechanisms Induced by Resveratrol

(2017) Guilherme Fernandes et al.   Nutrients

Resveratrol inhibits cell cycle progression by targeting Aurora kinase A and Polo-like kinase 1 in breast cancer cells

(2016) RUBICELI MEDINA-AGUILAR et al.   ONCOLOGY REPORTS

A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells

(2016) Rishabh Kala et al.   PLoS One

The molecular targets of resveratrol

(2015) Sameer S. Kulkarni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

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(2015) Nicole Stopa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium

(2015) S. Chen et al.   DEVELOPMENT

Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation

(2015) Mehtap Kilic Eren et al.   PLoS One

Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells

(2015) Fangfang Lang et al.   PLoS One

Post-Translational Modifications of Histones That Influence Nucleosome Dynamics

(2014) Gregory D. Bowman et al.   CHEMICAL REVIEWS

Resveratrol induces cell cycle arrest via a p53-independent pathway in A549 cells

(2014) LONG YUAN et al.   Molecular Medicine Reports

BRCA1 promoter hypermethylation in sporadic epithelial ovarian carcinoma: Association with low expression of BRCA1, improved survival and co-expression of DNA methyltransferases

(2014) XUEFENG BAI et al.   Oncology Letters

Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase

(2013) Lilian S. Gomez et al.   BIOCHIMIE

BRCA1 is a negative modulator of the PRC2 complex

(2013) Lan Wang et al.   EMBO JOURNAL

Expression of DNA Methyltransferases in Breast Cancer Patients and to Analyze the Effect of Natural Compounds on DNA Methyltransferases and Associated Proteins

(2013) Sameer Mirza et al.   Journal of Breast Cancer

Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression

(2013) M C C Sachweh et al.   Cell Death & Disease

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression

(2010) G. Rank et al.   BLOOD

Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation

(2010) Margaret Rush et al.   Epigenetics

Epigenetics and gene expression

(2010) E R Gibney et al.   HEREDITY

Resveratrol Arrests Cell Cycle and Induces Apoptosis in Human Hepatocellular Carcinoma Huh-7 Cells

(2010) Pei-Chi Liao et al.   JOURNAL OF MEDICINAL FOOD

Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells

(2010) Andreas J. Papoutsis et al.   JOURNAL OF NUTRITION

Transcriptional regulation of BRCA1 expression by a metabolic switch

(2010) Li-Jun Di et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing

(2009) Quan Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bmi1 regulates memory CD4 T cell survival via repression of theNoxagene

(2008) Masakatsu Yamashita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Arginine methylation regulates the p53 response

(2008) Martin Jansson et al.   NATURE CELL BIOLOGY

Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing

(2008) Xudong Wu et al.   NUCLEIC ACIDS RESEARCH