Rab GTPases: Switching to Human Diseases

Presenilins and γ-Secretase in Membrane Proteostasis

(2019) Naoto Oikawa et al.   Cells

The labyrinth unfolds: architectural rearrangements of the endolysosomal system in antigen-presenting cells

(2019) Priscillia Perrin et al.   CURRENT OPINION IN IMMUNOLOGY

The role of Rab GTPases in the pathobiology of Parkinson’ disease

(2019) Luis Bonet-Ponce et al.   CURRENT OPINION IN CELL BIOLOGY

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B

(2018) David Colecchia et al.   Autophagy

Rab and Arf proteins at the crossroad between membrane transport and cytoskeleton dynamics

(2018) Ingrid Kjos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals

(2018) Eugene Jennifer Jin et al.   CURRENT BIOLOGY

Rab GTPases and Membrane Trafficking in Neurodegeneration

(2018) Ferdi Ridvan Kiral et al.   CURRENT BIOLOGY

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

(2018) Anetta Härtlova et al.   EMBO JOURNAL

Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer’s Disease

(2018) Tingxiang Yan et al.   JOURNAL OF ALZHEIMERS DISEASE

RAB39A: a Rab small GTPase with a prominent role in cancer stemness

(2018) Tokuhiro Chano et al.   JOURNAL OF BIOCHEMISTRY

Rab 10-a traffic controller in multiple cellular pathways and locations

(2018) Christelle En Lin Chua et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

(2018) Jesús Madero-Pérez et al.   Molecular Neurodegeneration

Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration

(2018) Ga Ram Jeong et al.   Molecular Neurodegeneration

The emerging role of Rab GTPases in the pathogenesis of Parkinson's disease

(2018) Yujing Gao et al.   MOVEMENT DISORDERS

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

(2018) Yingxiao Shi et al.   NATURE MEDICINE

Molecular Insights into the Roles of Rab Proteins in Intracellular Dynamics and Neurodegenerative Diseases

(2018) Shobi Veleri et al.   NEUROMOLECULAR MEDICINE

Dysregulation of Rab5-mediated endocytic pathways in Alzheimer's disease

(2018) Wei Xu et al.   TRAFFIC

Rab35 GTPase and cancer: Linking membrane trafficking to tumorigenesis

(2018) Ronan Shaughnessy et al.   TRAFFIC

Rab GTPase Function in Endosome and Lysosome Biogenesis

(2018) Lars Langemeyer et al.   TRENDS IN CELL BIOLOGY

Prominent role of RAB39A-RXRB axis in cancer development and stemness

(2018) Tokuhiro Chano et al.   Oncotarget

Current Concepts of Antigen Cross-Presentation

(2018) Maria Embgenbroich et al.   Frontiers in Immunology

The Role of Rab GTPases in Alzheimer’s Disease

(2018) Xian Zhang et al.   ACS Chemical Neuroscience

The small GTPase Rab28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium

(2018) Guoxin Ying et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAB10: an Alzheimer’s disease resilience locus and potential drug target

(2018) Justina Tavana et al.   Clinical Interventions in Aging

Charcot Marie Tooth 2B Peripheral Sensory Neuropathy: How Rab7 Mutations Impact NGF Signaling?

(2017) Harry Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multivalent Rab interactions determine tether-mediated membrane fusion

(2017) Anna Lürick et al.   MOLECULAR BIOLOGY OF THE CELL

Rab5a is overexpressed in oral cancer and promotes invasion through ERK/MMP signaling

(2017) Di Zhang et al.   Molecular Medicine Reports

Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer’s Disease Pathogenesis

(2017) Katarzyna Marta Zoltowska et al.   MOLECULAR NEUROBIOLOGY

Rab GTPases: The Key Players in the Molecular Pathway of Parkinson’s Disease

(2017) Meng-meng Shi et al.   Frontiers in Cellular Neuroscience

Rab25 GTPase: Functional roles in cancer

(2017) Sisi Wang et al.   Oncotarget

Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

(2017) Perry G. Ridge et al.   Genome Medicine

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis

(2017) Martin Steger et al.   eLife

Rab GTPases in Immunity and Inflammation

(2017) Akriti Prashar et al.   Frontiers in Cellular and Infection Microbiology

Rab11-FIP2 promotes colorectal cancer migration and invasion by regulating PI3K/AKT/MMP7 signaling pathway

(2016) Chang-long Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP

(2016) Stefania Spanò et al.   Cell Host & Microbe

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

(2016) Chantal Sellier et al.   EMBO JOURNAL

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

(2016) Christopher P Webster et al.   EMBO JOURNAL

RAB2A controls MT1‐MMP endocytic and E‐cadherin polarized Golgi trafficking to promote invasive breast cancer programs

(2016) Hiroaki Kajiho et al.   EMBO REPORTS

Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment

(2016) Yuanyuan Li et al.   IMMUNITY

Bidirectional traffic between the Golgi and the endosomes – machineries and regulation

(2016) Cinzia Progida et al.   JOURNAL OF CELL SCIENCE

Rabs, Membrane Dynamics, and Parkinson's Disease

(2016) Bor Luen Tang   JOURNAL OF CELLULAR PHYSIOLOGY

Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway

(2016) Patricia Sheehan et al.   JOURNAL OF NEUROSCIENCE

Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth

(2016) Kotaro Furusawa et al.   JOURNAL OF NEUROSCIENCE

Charcot-Marie-Tooth 2b associated Rab7 mutations cause axon growth and guidance defects during vertebrate sensory neuron development

(2016) Olga Y. Ponomareva et al.   Neural Development

RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies

(2016) Kyndall Hodges et al.   NEUROBIOLOGY OF AGING

Broad clinical phenotype in Parkinsonism associated with a base pair deletion in RAB39B and additional POLG variant

(2016) Max Güldner et al.   PARKINSONISM & RELATED DISORDERS

Rab23 is overexpressed in human astrocytoma and promotes cell migration and invasion through regulation of Rac1

(2016) Minghao Wang et al.   TUMOR BIOLOGY

C9orf72’s Interaction with Rab GTPases—Modulation of Membrane Traffic and Autophagy

(2016) Bor L. Tang   Frontiers in Cellular Neuroscience

Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening

(2016) Kerstin Klinkert et al.   Nature Communications

Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis

(2016) Patricio Silva et al.   Oncotarget

shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity

(2016) Susana A. Gonçalves et al.   PLoS Genetics

Recycling at synapses

(2016) Owen P Gross et al.   eLife

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

(2016) Martin Steger et al.   eLife

Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS

(2015) Kai Y. Soo et al.   ACTA NEUROPATHOLOGICA

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

(2015) Y.-C. Lai et al.   EMBO JOURNAL

Inactivation of Rab23 inhibits the invasion and motility of pancreatic duct adenocarcinoma

(2015) Z.Z. Cai et al.   GENETICS AND MOLECULAR RESEARCH

Cellular functions of Rab GTPases at a glance

(2015) Y. Zhen et al.   JOURNAL OF CELL SCIENCE

A role for Rab23 in the trafficking of Kif17 to the primary cilium

(2015) Y. S. Lim et al.   JOURNAL OF CELL SCIENCE

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Rab40b upregulation correlates with the prognosis of gastric cancer by promoting migration, invasion, and metastasis

(2015) Yuanyuan Li et al.   MEDICAL ONCOLOGY

The RAB39B p.G192R mutation causes X-linked dominant Parkinson’s disease

(2015) Ignacio F. Mata et al.   Molecular Neurodegeneration

Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease

(2015) S Kim et al.   MOLECULAR PSYCHIATRY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Identification of an oncogenic RAB protein

(2015) D. B. Wheeler et al.   SCIENCE

Overexpression of Rab5a promotes hepatocellular carcinoma cell proliferation and invasion via FAK signaling pathway

(2015) Donghua Geng et al.   TUMOR BIOLOGY

Rab23 is overexpressed in human bladder cancer and promotes cancer cell proliferation and invasion

(2015) Yuanjun Jiang et al.   TUMOR BIOLOGY

The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition

(2015) Maria Lidia Mignogna et al.   Nature Communications

Aberrant amino acid signaling promotes growth and metastasis of hepatocellular carcinomas through Rab1A-dependent activation of mTORC1 by Rab1A

(2015) Bi-Hong Xu et al.   Oncotarget

RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport

(2015) Caitlin A. Taylor et al.   PLoS Genetics

Dopamine receptors reveal an essential role of IFT-B, KIF17, and Rab23 in delivering specific receptors to primary cilia

(2015) Alison Leaf et al.   eLife

Lpg0393 of Legionella pneumophila Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22

(2015) Young-Sik Sohn et al.   PLoS One

Mutations in RAB39B Cause X-Linked Intellectual Disability and Early-Onset Parkinson Disease with α-Synuclein Pathology

(2014) Gabrielle R. Wilson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prenatal findings in carpenter syndrome and a novel mutation inRAB23

(2014) Damien Haye et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Rab1A Is an mTORC1 Activator and a Colorectal Oncogene

(2014) Janice D. Thomas et al.   CANCER CELL

MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development

(2014) Xiao-Hui Xu et al.   CELL RESEARCH

Synaptic vesicle recycling: steps and principles

(2014) S. O. Rizzoli   EMBO JOURNAL

The small GTPase Rab11 co-localizes with  -synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity

(2014) O. Chutna et al.   HUMAN MOLECULAR GENETICS

Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour

(2014) Carlo Breda et al.   HUMAN MOLECULAR GENETICS

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

(2014) Manal A. Farg et al.   HUMAN MOLECULAR GENETICS

LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity

(2014) Patricia Gómez-Suaga et al.   HUMAN MOLECULAR GENETICS

Small GTPase Rab17 Regulates the Surface Expression of Kainate Receptors but Not α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors in Hippocampal Neurons via Dendritic Trafficking of Syntaxin-4 Protein

(2014) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration

(2014) M. Borg et al.   JOURNAL OF CELL SCIENCE

The role of the small GTPase Rab31 in cancer

(2014) Christelle En Lin Chua et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

JIP1 Mediates Anterograde Transport of Rab10 Cargos during Neuronal Polarization

(2014) C.-Y. Deng et al.   JOURNAL OF NEUROSCIENCE

Rab5 and Rab4 Regulate Axon Elongation in the Xenopus Visual System

(2014) J. Falk et al.   JOURNAL OF NEUROSCIENCE

The role of the LRRK2 gene in Parkinsonism

(2014) Jie-Qiong Li et al.   Molecular Neurodegeneration

α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner

(2014) Guowei Yin et al.   NEUROBIOLOGY OF DISEASE

Human Rab7 mutation mimics features of Charcot–Marie–Tooth neuropathy type 2B in Drosophila

(2014) Katrien Janssens et al.   NEUROBIOLOGY OF DISEASE

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

(2014) T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

(2014) A. Beilina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocytosis of Viruses and Bacteria

(2014) P. Cossart et al.   Cold Spring Harbor Perspectives in Biology

A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production

(2014) Vinod Udayar et al.   Cell Reports

The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs

(2013) Timothy P. Levine et al.   BIOINFORMATICS

Rab GTPase regulation of membrane identity

(2013) Suzanne R Pfeffer   CURRENT OPINION IN CELL BIOLOGY

A novel RAB7 mutation in a Chinese family with Charcot–Marie–Tooth type 2B disease

(2013) Xing Wang et al.   GENE

Mutation Spectrum inRAB3GAP1,RAB3GAP2, andRAB18and Genotype-Phenotype Correlations in Warburg Micro Syndrome and Martsolf Syndrome

(2013) Mark T. Handley et al.   HUMAN MUTATION

Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells

(2013) A. Jacob et al.   JOURNAL OF CELL SCIENCE

Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells

(2013) P. Mendoza et al.   JOURNAL OF CELL SCIENCE

Defective Axonal Transport of Rab7 GTPase Results in Dysregulated Trophic Signaling

(2013) K. Zhang et al.   JOURNAL OF NEUROSCIENCE

BDNF Regulates Rab11-Mediated Recycling Endosome Dynamics to Induce Dendritic Branching

(2013) O. M. Lazo et al.   JOURNAL OF NEUROSCIENCE

Endocytosis and Cancer

(2013) I. Mellman et al.   Cold Spring Harbor Perspectives in Biology

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development

(2013) Yang Liu et al.   Nature Communications

Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function

(2013) Smita Cherry et al.   eLife

Charcot–Marie–Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin

(2012) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Abnormal intestinal permeability in Crohn's disease pathogenesis

(2012) Christopher W. Teshima et al.   Annals of the New York Academy of Sciences

An emerging role for LRRK2 in the immune system

(2012) Nicolas Dzamko et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Rab25 Is a Tumor Suppressor Gene with Antiangiogenic and Anti-Invasive Activities in Esophageal Squamous Cell Carcinoma

(2012) M. Tong et al.   CANCER RESEARCH

Membrane trafficking in neuronal maintenance and degeneration

(2012) Dong Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rab11-Family of Interacting Protein 2 associates with chlamydial inclusions through its Rab-binding domain and promotes bacterial multiplication

(2012) Natalia Leiva et al.   CELLULAR MICROBIOLOGY

Gene expression signatures differentiate uterine endometrial stromal sarcoma from leiomyosarcoma

(2012) Ben Davidson et al.   GYNECOLOGIC ONCOLOGY

Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease

(2012) Joern R. Steinert et al.   HUMAN MOLECULAR GENETICS

Small GTPase Rab17 Regulates Dendritic Morphogenesis and Postsynaptic Development of Hippocampal Neurons

(2012) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkinson’s disease and immune system: is the culprit LRRKing in the periphery?

(2012) Elisa Greggio et al.   Journal of Neuroinflammation

Rab33a Mediates Anterograde Vesicular Transport for Membrane Exocytosis and Axon Outgrowth

(2012) H. Nakazawa et al.   JOURNAL OF NEUROSCIENCE

Rab10 GTPase regulates ER dynamics and morphology

(2012) Amber R. English et al.   NATURE CELL BIOLOGY

Coordination between RAB GTPase and phosphoinositide regulation and functions

(2012) Steve Jean et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Charcot–Marie–Tooth disease and intracellular traffic

(2012) Cecilia Bucci et al.   PROGRESS IN NEUROBIOLOGY

A Rab32-Dependent Pathway Contributes to Salmonella Typhi Host Restriction

(2012) S. Spano et al.   SCIENCE

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

(2012) K. McGourty et al.   SCIENCE

VipD of Legionella pneumophila Targets Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages

(2012) Bonsu Ku et al.   PLoS Pathogens

Loss-of-Function Mutations in RAB18 Cause Warburg Micro Syndrome

(2011) Danai Bem et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

The Cell Biology of Phagocytosis

(2011) Ronald S. Flannagan et al.   Annual Review of Pathology-Mechanisms of Disease

Erratum: Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

(2011) P Richards et al.   CELL DEATH AND DIFFERENTIATION

Endosome-mediated retrograde axonal transport of P2X3 receptor signals in primary sensory neurons

(2011) Xu-Qiao Chen et al.   CELL RESEARCH

Systematic Discovery of Rab GTPases with Synaptic Functions in Drosophila

(2011) Chih-Chiang Chan et al.   CURRENT BIOLOGY

Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning

(2011) M. W. Dodson et al.   HUMAN MOLECULAR GENETICS

DENN Domain Proteins: Regulators of Rab GTPases

(2011) Andrea L. Marat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

(2011) Stephen D. Ginsberg et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella

(2011) S. Spano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CMT2B-associated Rab7 mutants inhibit neurite outgrowth

(2010) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Mutations in the Small GTPase Gene RAB39B Are Responsible for X-linked Mental Retardation Associated with Autism, Epilepsy, and Macrocephaly

(2010) Maila Giannandrea et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome

(2010) Guntram Borck et al.   HUMAN GENETICS

The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes

(2010) Harald Husebye et al.   IMMUNITY

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

(2010) Shin-ichiro Yoshimura et al.   JOURNAL OF CELL BIOLOGY

Rab7b controls trafficking from endosomes to the TGN

(2010) C. Progida et al.   JOURNAL OF CELL SCIENCE

Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas

(2010) Ki Taek Nam et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative Analysis of Synaptic Vesicle Rabs Uncovers Distinct Yet Overlapping Roles for Rab3a and Rab27b in Ca2+-Triggered Exocytosis

(2010) N. J. Pavlos et al.   JOURNAL OF NEUROSCIENCE

Rab11 and Its Effector Rab Coupling Protein Contribute to the Trafficking of  1 Integrins during Axon Growth in Adult Dorsal Root Ganglion Neurons and PC12 Cells

(2010) R. Eva et al.   JOURNAL OF NEUROSCIENCE

Rab GTPases-Dependent Endocytic Pathways Regulate Neuronal Migration and Maturation through N-Cadherin Trafficking

(2010) Takeshi Kawauchi et al.   NEURON

Mycobacterial Nucleoside Diphosphate Kinase Blocks Phagosome Maturation in Murine Raw 264.7 Macrophages

(2010) Jim Sun et al.   PLoS One

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

New links between vesicle coats and Rab-mediated vesicle targeting

(2010) Cortney G. Angers et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion

(2009) S Hooper et al.   BRITISH JOURNAL OF CANCER

Anterograde Transport of TrkB in Axons Is Mediated by Direct Interaction with Slp1 and Rab27

(2009) Nariko Arimura et al.   DEVELOPMENTAL CELL

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation

(2009) Brett A. McCray et al.   HUMAN MOLECULAR GENETICS

Tumor suppressor function of Rab25 in triple-negative breast cancer

(2009) Ji-Ming Cheng et al.   INTERNATIONAL JOURNAL OF CANCER

APP Anterograde Transport Requires Rab3A GTPase Activity for Assembly of the Transport Vesicle

(2009) A. Szodorai et al.   JOURNAL OF NEUROSCIENCE

Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

(2009) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Regulation of endocytosis via the oxygen-sensing pathway

(2009) Yi Wang et al.   NATURE MEDICINE

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

(2009) Xueyi Li et al.   NEUROBIOLOGY OF DISEASE

Characterization of the Rab7K157N mutant protein associated with Charcot–Marie-Tooth type 2B

(2008) Azzurra De Luca et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Integrative Genomics Identifies RAB23 as an Invasion Mediator Gene in Diffuse-Type Gastric Cancer

(2008) Q. Hou et al.   CANCER RESEARCH

Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6

(2008) Sophia Semerdjieva et al.   JOURNAL OF CELL BIOLOGY

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE

Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes

(2008) Daisuke Satoh et al.   NATURE CELL BIOLOGY

Role of Rab27 in synaptic transmission at the squid giant synapse

(2008) E. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA