Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer’s Disease

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson’s disease

(2017) Zhong-Can Chen et al.   Science Signaling

Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

(2017) Perry G. Ridge et al.   Genome Medicine

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson’s disease

(2017) Zhong-Can Chen et al.   Science Signaling

Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells

(2017) Kenneth Thirstrup et al.   Scientific Reports

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity

(2016) Sathish Kumar et al.   ACTA NEUROPATHOLOGICA

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

(2016) G. Ito et al.   BIOCHEMICAL JOURNAL

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

(2016) Martin Steger et al.   eLife

RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport

(2015) Caitlin A. Taylor et al.   PLoS Genetics

RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization

(2015) Wei Zou et al.   PLoS Genetics

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Tau protein kinases: Involvement in Alzheimer's disease

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes

(2012) Yu Chen et al.   JOURNAL OF CELL BIOLOGY

Lgl1 Activation of Rab10 Promotes Axonal Membrane Trafficking Underlying Neuronal Polarization

(2011) Tong Wang et al.   DEVELOPMENTAL CELL

Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles

(2010) K. E. Funk et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane

(2010) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LRRK2 variant associated with Alzheimer's disease

(2009) Yi Zhao et al.   NEUROBIOLOGY OF AGING