Multivalent Rab interactions determine tether-mediated membrane fusion

The HOPS/Class C Vps Complex Tethers High-Curvature Membranes via a Direct Protein-Membrane Interaction

(2016) Ruoya Ho et al.   TRAFFIC

The HabcDomain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion

(2015) Anna Lürick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity

(2015) Rik van der Kant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane

(2015) Ruoya Ho et al.   MOLECULAR BIOLOGY OF THE CELL

Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion

(2015) Amy Orr et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of Rab11–FIP3–Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11

(2015) Melanie Vetter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly

(2015) R. W. Baker et al.   SCIENCE

Structure of Rab11–FIP3–Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11

(2015) Melanie Vetter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Principles of membrane tethering and fusion in endosome and lysosome biogenesis

(2014) Daniel Kümmel et al.   CURRENT OPINION IN CELL BIOLOGY

The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes

(2014) M. Cabrera et al.   JOURNAL OF CELL SCIENCE

The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins

(2014) M. Wong et al.   SCIENCE

SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18

(2014) Braden T Lobingier et al.   eLife

Rab GTPases and membrane identity: Causal or inconsequential?

(2013) Francis A. Barr   JOURNAL OF CELL BIOLOGY

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

(2013) H. J. k. Balderhaar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release

(2012) Jörg Malsam et al.   EMBO JOURNAL

Phosphorylation of the effector complex HOPS by the vacuolar kinase Yck3p confers Rab nucleotide specificity for vacuole docking and fusion

(2012) Michael Zick et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

(2012) C. Brocker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic

(2011) Rachael L. Plemel et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of exocytosis by the exocyst subunit Sec6 and the SM protein Sec1

(2011) Francesca Morgera et al.   MOLECULAR BIOLOGY OF THE CELL

The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7

(2010) Mirjana Nordmann et al.   CURRENT BIOLOGY

Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering

(2010) Margarita Cabrera et al.   JOURNAL OF CELL BIOLOGY

HOPS Initiates Vacuole Docking by Tethering Membranes before trans-SNARE Complex Assembly

(2010) Christopher M. Hickey et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)

(2010) A. Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defined Subunit Arrangement and Rab Interactions Are Required for Functionality of the HOPS Tethering Complex

(2010) Clemens W. Ostrowicz et al.   TRAFFIC

Vps41 Phosphorylation and the Rab Ypt7 Control the Targeting of the HOPS Complex to Endosome–Vacuole Fusion Sites

(2009) Margarita Cabrera et al.   MOLECULAR BIOLOGY OF THE CELL

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes

(2009) Takeshi Ohya et al.   NATURE

Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components

(2009) C. Stroupe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab and Arl GTPase Family Members Cooperate in the Localization of the Golgin GCC185

(2008) Alondra Schweizer Burguete et al.   CELL

Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

(2008) Christopher L. Brett et al.   JOURNAL OF CELL BIOLOGY

HOPS Proofreads the trans-SNARE Complex for Yeast Vacuole Fusion

(2008) Vincent J. Starai et al.   MOLECULAR BIOLOGY OF THE CELL

Genome-wide Analysis of AP-3–dependent Protein Transport in Yeast

(2008) Vikram C. Anand et al.   MOLECULAR BIOLOGY OF THE CELL

Asymmetric Tethering of Flat and Curved Lipid Membranes by a Golgin

(2008) G. Drin et al.   SCIENCE