Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function

Defective Axonal Transport of Rab7 GTPase Results in Dysregulated Trophic Signaling

(2013) K. Zhang et al.   JOURNAL OF NEUROSCIENCE

Charcot–Marie–Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin

(2012) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Autophagy, neuron-specific degradation and neurodegeneration

(2012) Dong Wang et al.   Autophagy

Membrane trafficking in neuronal maintenance and degeneration

(2012) Dong Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Cause Delayed Growth Factor Receptor Transport and Altered Endosomal and Nuclear Signaling

(2012) Soumik BasuRay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The synaptic vesicle SNARE neuronal Synaptobrevin promotes endolysosomal degradation and prevents neurodegeneration

(2012) Adam Haberman et al.   JOURNAL OF CELL BIOLOGY

RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans

(2012) Olga Skorobogata et al.   PLoS One

Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos

(2012) Nobuyuki Kawamura et al.   Nature Communications

Systematic Discovery of Rab GTPases with Synaptic Functions in Drosophila

(2011) Chih-Chiang Chan et al.   CURRENT BIOLOGY

Clarifying lysosomal storage diseases

(2011) Mark L. Schultz et al.   TRENDS IN NEUROSCIENCES

CMT2B-associated Rab7 mutants inhibit neurite outgrowth

(2010) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

A dual function of V0-ATPase a1 provides an endolysosomal degradation mechanism inDrosophila melanogasterphotoreceptors

(2010) W. Ryan Williamson et al.   JOURNAL OF CELL BIOLOGY

The mood stabilizer valproic acid improves defective neurite formation caused by charcot-marie-tooth disease-associated mutant Rab7 through the JNK signaling pathway

(2010) Junji Yamauchi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Preparation of Developing and Adult Drosophila Brains and Retinae for Live Imaging

(2010) W. Ryan Williamson et al.   Jove-Journal of Visualized Experiments

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation

(2009) Brett A. McCray et al.   HUMAN MOLECULAR GENETICS

Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration

(2009) Yashodhan Chinchore et al.   PLoS Genetics

Electrophysiological Methods for Recording Synaptic Potentials from the NMJ of Drosophila Larvae

(2009) Wendy Imlach et al.   Jove-Journal of Visualized Experiments

Characterization of the Rab7K157N mutant protein associated with Charcot–Marie-Tooth type 2B

(2008) Azzurra De Luca et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY