Occurrence and toxicity of a fusarium mycotoxin, zearalenone

Zearalenone Induces Estrogen-Receptor-Independent Neutrophil Extracellular Trap Release in Vitro

(2019) Jing-Jing Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Detoxification Strategies for Zearalenone Using Microorganisms: A Review

(2019) Nan Wang et al.   Microorganisms

Zearalenone-Promoted Follicle Growth through Modulation of Wnt-1/β-Catenin Signaling Pathway and Expression of Estrogen Receptor Genes in Ovaries of Postweaning Piglets

(2018) Li-Jie Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Zearalenone and alpha-zearalenol inhibit the synthesis and secretion of pig follicle stimulating hormone via the non-classical estrogen membrane receptor GPR30

(2018) Jing He et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen Receptor α Is Crucial in Zearalenone-Induced Invasion and Migration of Prostate Cancer Cells

(2018) Karolina Kowalska et al.   Toxins

Effects of Zearalenone Exposure on the TGF-β1/Smad3 Signaling Pathway and the Expression of Proliferation or Apoptosis Related Genes of Post-Weaning Gilts

(2018) Min Zhou et al.   Toxins

ROS-Mediated Cell Cycle Arrest and Apoptosis Induced by Zearalenone in Mouse Sertoli Cells via ER Stress and the ATP/AMPK Pathway

(2018) Wang-Long Zheng et al.   Toxins

Individual and Combined Occurrence of Mycotoxins in Feed Ingredients and Complete Feeds in China

(2018) Rui Ma et al.   Toxins

Zearalenone exposure elevated the expression of tumorigenesis genes in mouse ovarian granulosa cells

(2018) Rui-Qian Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Effects of Autophagy and PI3K/AKT/m-TOR Signaling Pathway on the Cell-Cycle Arrest of Rats Primary Sertoli Cells Induced by Zearalenone

(2018) Bing-jie Wang et al.   Toxins

Zearalenone Exposure Enhanced the Expression of Tumorigenesis Genes in Donkey Granulosa Cells via the PTEN/PI3K/AKT Signaling Pathway

(2018) Guo-Liang Zhang et al.   Frontiers in Genetics

Presence of Zearalenone in Cereal Grains and Its Exposure Risk Assessment in Indian Population

(2018) Ankita Rai et al.   JOURNAL OF FOOD SCIENCE

Zearalenone causes embryotoxicity and induces oxidative stress and apoptosis in differentiated human embryonic stem cells

(2018) Hanwen Cao et al.   TOXICOLOGY IN VITRO

Combined effects of deoxynivalenol and zearalenone on oxidative injury and apoptosis in porcine splenic lymphocytes in vitro

(2017) Zhihua Ren et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Evaluation of immunomodulatory effects of zearalenone in mice

(2017) Mohammad Rafiqul Islam et al.   Journal of Immunotoxicology

Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line

(2017) Diqi Yang et al.   REPRODUCTIVE TOXICOLOGY

The impact of Zearalenone on the meiotic progression and primordial follicle assembly during early oogenesis

(2017) Ke-Han Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative damage and disturbance of antioxidant capacity by zearalenone and its metabolites in human cells

(2017) Elena Tatay et al.   TOXICOLOGY IN VITRO

Individual and Combined Effects of Fumonisin B1, Deoxynivalenol and Zearalenone on the Hepatic and Renal Membrane Lipid Integrity of Rats

(2017) András Szabó et al.   Toxins

Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway

(2017) Miao Yu et al.   Toxins

Zearalenone (ZEN) and Its Influence on Regulation of Gene Expression in Carp (Cyprinus carpio L.) Liver Tissue

(2017) Constanze Pietsch   Toxins

Metabolism of Zearalenone and Its Major Modified Forms in Pigs

(2017) Sabina Binder et al.   Toxins

Biomonitoring of the mycotoxin Zearalenone: current state-of-the art and application to human exposure assessment

(2016) Angela Mally et al.   ARCHIVES OF TOXICOLOGY

Zearalenone as an endocrine disruptor in humans

(2016) Karolina Kowalska et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Effect of the Fusarium toxins, zearalenone and deoxynivalenol, on the mouse brain

(2016) Z.H. Ren et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cytotoxic effects of zearalenone and its metabolites and antioxidant cell defense in CHO-K1 cells

(2016) Elena Tatay et al.   FOOD AND CHEMICAL TOXICOLOGY

Regulation of oncogenes and gap junction intercellular communication during the proliferative response of zearalenone in TM3 cells

(2016) W Zheng et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Prepubertal exposure to an oestrogenic mycotoxin zearalenone induces central precocious puberty in immature female rats through the mechanism of premature activation of hypothalamic kisspeptin-GPR54 signaling

(2016) Rong Yang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

In vitro effects of deoxynivalenol and zearalenone major metabolites alone and combined, on cell proliferation, steroid production and gene expression in bovine small-follicle granulosa cells

(2016) Fabiola Pizzo et al.   TOXICON

Zearalenone and its metabolites in urine and breast cancer risk: A case-control study in Tunisia

(2015) H. Belhassen et al.   CHEMOSPHERE

Individual and combined effects of deoxynivalenol and zearalenone on mouse kidney

(2015) Zhen Liang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Invited review: Diagnosis of zearalenone (ZEN) exposure of farm animals and transfer of its residues into edible tissues (carry over)

(2015) Sven Dänicke et al.   FOOD AND CHEMICAL TOXICOLOGY

In vivo toxicity studies of fusarium mycotoxins in the last decade: A review

(2015) L. Escrivá et al.   FOOD AND CHEMICAL TOXICOLOGY

Zearalenone-induced changes in biochemical parameters, oxidative stress and apoptosis in cardiac tissue

(2015) I Ben Salem et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Endoplasmic Reticulum Stress Cooperates in Zearalenone-Induced Cell Death of RAW 264.7 Macrophages

(2015) Fenglei Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparative Toxicokinetics, Absolute Oral Bioavailability, and Biotransformation of Zearalenone in Different Poultry Species

(2015) Mathias Devreese et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Interactions of zearalenone with native and chemically modified cyclodextrins and their potential utilization

(2015) Miklós Poór et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Zearalenone metabolism in human placental subcellular organelles, JEG - 3 cells, and recombinant CYP19A1

(2015) Pasi Huuskonen et al.   PLACENTA

The nonsteroidal mycoestrogen zearalenone and its five metabolites suppress LH secretion from the bovine anterior pituitary cells via the estradiol receptor GPR30 in vitro

(2015) Urara Nakamura et al.   THERIOGENOLOGY

Biotransformation of zearalenone and zearalenols to their major glucuronide metabolites reduces estrogenic activity

(2015) Caroline Frizzell et al.   TOXICOLOGY IN VITRO

Estrogenicity of novel phase I and phase II metabolites of zearalenone and cis-zearalenone

(2015) Sarah S. Drzymala et al.   TOXICON

Zinc inhibits the reproductive toxicity of Zearalenone in immortalized murine ovarian granular KK-1 cells

(2015) Yijia Li et al.   Scientific Reports

In vitro screening of environmental chemicals identifies zearalenone as a novel substrate of the placental BCRP/ABCG2 transporter

(2015) Jingcheng Xiao et al.   Toxicology Research

Zearalenone induces oxidative damage involving Keap1/Nrf2/HO-1 pathway in hepatic L02 cells

(2015) Kejia Wu et al.   Molecular & Cellular Toxicology

Oxidative Stress Induced by Zearalenone in Porcine Granulosa Cells and Its Rescue by Curcumin In Vitro

(2015) Xunsi Qin et al.   PLoS One

Zearalenone Mycotoxin Affects Immune Mediators, MAPK Signalling Molecules, Nuclear Receptors and Genome-Wide Gene Expression in Pig Spleen

(2015) Gina Cecilia Pistol et al.   PLoS One

Zearalenone exposure affects mouse oocyte meiotic maturation and granulosa cell proliferation

(2014) Yan-Jun Hou et al.   ENVIRONMENTAL TOXICOLOGY

Hepatotoxic effects of mycotoxin combinations in mice

(2014) Lv-Hui Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

Zearalenone induced toxicity in SHSY-5Y cells: The role of oxidative stress evidenced by N-acetyl cysteine

(2014) M. Venkataramana et al.   FOOD AND CHEMICAL TOXICOLOGY

Natural occurrence of deoxynivalenol and zearalenone in wheat from Jiangsu province, China

(2014) Fang Ji et al.   FOOD CHEMISTRY

Biochemical changes and oxidative stress induced by zearalenone in the liver of pregnant rats

(2014) C Zhou et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Gene Expression Profile and Toxic Effects in Human Bronchial Epithelial Cells Exposed to Zearalenone

(2014) Mei Yu So et al.   PLoS One

Toxic Effects of Maternal Zearalenone Exposure on Intestinal Oxidative Stress, Barrier Function, Immunological and Morphological Changes in Rats

(2014) Min Liu et al.   PLoS One

Effect of zearalenone on reproductive parameters and expression of selected testicular genes in mice

(2014) E. Zatecka et al.   REPRODUCTIVE TOXICOLOGY

Multigenerational exposure to dietary zearalenone (ZEA), an estrogenic mycotoxin, affects puberty and reproduction in female mice

(2014) Fei Zhao et al.   REPRODUCTIVE TOXICOLOGY

Phytoestrogenα-Zearalanol Improves Memory Impairment and Hippocampal Neurogenesis in Ovariectomized Mice

(2014) Yilong Dong et al.   TheScientificWorldJOURNAL

Assessing the effect of food mycotoxins on aromatase by using a cell-based system

(2014) Yanfei Wang et al.   TOXICOLOGY IN VITRO

Zearalenone inhibits testosterone biosynthesis in mouse Leydig cells via the crosstalk of estrogen receptor signaling and orphan nuclear receptor Nur77 expression

(2014) Qing Liu et al.   TOXICOLOGY IN VITRO

Zearalenone induces apoptosis and cytoprotective autophagy in primary Leydig cells

(2014) Yajun Wang et al.   TOXICOLOGY LETTERS

Zearalenone, an Estrogenic Mycotoxin, Is an Immunotoxic Compound

(2014) Isis Hueza et al.   Toxins

Natural feed contaminant zearalenone decreases the expressions of important pro- and anti-inflammatory mediators and mitogen-activated protein kinase/NF-κB signalling molecules in pigs

(2013) Gina Cecilia Pistol et al.   BRITISH JOURNAL OF NUTRITION

Significance of regulation limits in mycotoxin contamination in Asia and risk management programs at the national level

(2013) Nampeung Anukul et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Effect of zeranol on expression of apoptotic and cell cycle proteins in murine placentae

(2013) Yanfei Wang et al.   TOXICOLOGY

Cellular mechanisms of the cytotoxic effects of the zearalenone metabolites α-zearalenol and β-zearalenol on RAW264.7 macrophages

(2013) Jia Lu et al.   TOXICOLOGY IN VITRO

Co-occurrence of aflatoxins B1, B2, G1and G2, ochratoxin A, zearalenone, deoxynivalenol, and citreoviridin in rice in Brazil

(2012) M.I. Almeida et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

(2012) Ann Osselaere et al.   FOOD AND CHEMICAL TOXICOLOGY

Contamination of maize with deoxynivalenol and zearalenone in Croatia

(2012) Jelka Pleadin et al.   FOOD CONTROL

Occurrence of fumonisins and zearalenone in maize stored in family farm in Minas Gerais, Brazil

(2012) Valéria Aparecida Vieira Queiroz et al.   FOOD CONTROL

Transgenerational toxicity of Zearalenone in pigs

(2012) Eric J. Schoevers et al.   REPRODUCTIVE TOXICOLOGY

Zearalenone exposure modulates the expression of ABC transporters and nuclear receptors in pregnant rats and fetal liver

(2012) Farah Koraichi et al.   TOXICOLOGY LETTERS

Genotoxicity and inactivation of catechol metabolites of the mycotoxin zearalenone

(2012) Stefanie C. Fleck et al.   Mycotoxin Research

Occurrence of zearalenone, an oestrogenic mycotoxin, in Catalonia (Spain) and exposure assessment

(2011) G. Cano-Sancho et al.   FOOD AND CHEMICAL TOXICOLOGY

The levels of zearalenone and its metabolites in plasma, urine and faeces of horses fed with naturally, Fusarium toxin-contaminated oats

(2011) P. Songsermsakul et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Effect on hepatonephric organs, serum metabolites and oxidative stress in post-weaning piglets fed purified zearalenone-contaminated diets with or without Calibrin-Z

(2011) S. Z. Jiang et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells

(2011) Ratana Banjerdpongchai et al.   Journal of Hematology & Oncology

Dose-response effects of estrogenic mycotoxins (zearalenone, alpha- and beta-zearalenol) on motility, hyperactivation and the acrosome reaction of stallion sperm

(2011) Angela Filannino et al.   Reproductive Biology and Endocrinology

A note on the occurrence of mycotoxins in cereals and animal feedstuffs in Kwazulu Natal, South Africa 1984-1993

(2011) MF Dutton et al.   SOUTH AFRICAN JOURNAL OF ANIMAL SCIENCE

Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis

(2011) C. Frizzell et al.   TOXICOLOGY LETTERS

17β-Estradiol Regulates Cultured Immature Boar Sertoli Cell Proliferation via the cAMP-ERK1/2 Pathway and the Estrogen Receptor β

(2010) Xian-zhong WANG et al.   Agricultural Sciences in China

Co-occurrence of Aflatoxins, Ochratoxin A, Fumonisins, and Zearalenone in Cereals and Feed, Determined by Competitive Direct Enzyme-Linked Immunosorbent Assay and Thin-Layer Chromatography

(2010) Maja Klarić et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Co-occurrence of aflatoxins, ochratoxin A and zearalenone in Capsicum powder samples available on the Spanish market

(2010) L. Santos et al.   FOOD CHEMISTRY

Glucuronidation of zearalenone, zeranol and four metabolites in vitro: Formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms

(2010) Erika Pfeiffer et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of zearalenone and its derivatives on the innate immune response of swine

(2010) Daniela E. Marin et al.   TOXICON

Expression profiling of the genes responding to zearalenone and its analogues using estrogen-responsive genes

(2009) Meher Parveen et al.   FEBS LETTERS

Occurrence of Fusarium mycotoxins in maize imported into the UK, 2004–2007

(2009) K.A. Scudamore et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Oestrogenic mycotoxin exposures and precocious pubertal development

(2009) F. Massart et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

In Vitro Cytochrome P450 Formation of a Mono-Hydroxylated Metabolite of Zearalenone Exhibiting Estrogenic Activities: Possible Occurrence of This Metabolite in Vivo

(2009) Frederique Bravin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disposition, Oral Bioavailability, and Tissue Distribution of Zearalenone in Rats at Various Dose Levels

(2009) Beom Soo Shin et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Physiologically Based Pharmacokinetics of Zearalenone

(2009) Beom Soo Shin et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro

(2009) Erika Pfeiffer et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mycobiota and mycotoxins in fermented feed, wheat grains and corn grains in Southeastern Buenos Aires Province, Argentina

(2009) Marcela Beatriz Roigé et al.   REVISTA IBEROAMERICANA DE MICOLOGIA

Raphanus sativus extract protects against Zearalenone induced reproductive toxicity, oxidative stress and mutagenic alterations in male Balb/c mice

(2009) Jalila Ben Salah-Abbès et al.   TOXICON

The toxic effects and fate of intravenously administered zearalenone in goats

(2009) M. Dong et al.   TOXICON

Co-occurrence of deoxynivalenol and zearalenone in crops marketed in Portugal

(2008) M.F. Marques et al.   Food Additives & Contaminants Part B-Surveillance

Contaminants and microorganisms in Dutch organic food products: a comparison with conventional products

(2008) L.A.P. Hoogenboom et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Incidence of zearalenone and fumonisins in Bulgarian cereal production

(2008) Radostina Manova et al.   FOOD CONTROL

High Growth Rate of Girls with Precocious Puberty Exposed to Estrogenic Mycotoxins

(2008) Francesco Massart et al.   JOURNAL OF PEDIATRICS

Influence of in vitro exposure to mycotoxin zearalenone and its derivatives on swine sperm quality

(2008) E. Benzoni et al.   REPRODUCTIVE TOXICOLOGY

Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells

(2008) Chayma Bouaziz et al.   TOXICOLOGY