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Title
Mechanotransduction: from the cell surface to the nucleus via RhoA
Authors
Keywords
-
Journal
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
Volume 374, Issue 1779, Pages 20180229
Publisher
The Royal Society
Online
2019-07-01
DOI
10.1098/rstb.2018.0229
References
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- (2017) Sangkyun Cho et al. JOURNAL OF CELL BIOLOGY
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- (2017) Yekaterina A. Miroshnikova et al. JOURNAL OF CELL SCIENCE
- Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA
- (2017) Ketan Thakar et al. MOLECULAR BIOLOGY OF THE CELL
- Mechanotransduction and nuclear function
- (2016) David M Graham et al. CURRENT OPINION IN CELL BIOLOGY
- Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity
- (2016) Abhishek Kumar et al. JOURNAL OF CELL BIOLOGY
- p66 Shc Couples Mechanical Signals to RhoA through Focal Adhesion Kinase-Dependent Recruitment of p115-RhoGEF and GEF-H1
- (2016) Ru-Feng Wu et al. MOLECULAR AND CELLULAR BIOLOGY
- Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF
- (2016) David W. Scott et al. MOLECULAR BIOLOGY OF THE CELL
- ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
- (2016) M. Raab et al. SCIENCE
- Nuclear envelope rupture and repair during cancer cell migration
- (2016) C. M. Denais et al. SCIENCE
- Therapy for idiopathic pulmonary fibrosis: lessons from pooled data analyses
- (2015) Lauren K. Troy et al. EUROPEAN RESPIRATORY JOURNAL
- Extracellular rigidity sensing by talin isoform-specific mechanical linkages
- (2015) Katharina Austen et al. NATURE CELL BIOLOGY
- Mechanism of Focal Adhesion Kinase Mechanosensing
- (2015) Jing Zhou et al. PLoS Computational Biology
- The RhoA Guanine Nucleotide Exchange Factor, LARG, Mediates ICAM-1-Dependent Mechanotransduction in Endothelial Cells To Stimulate Transendothelial Migration
- (2014) E. C. Lessey-Morillon et al. JOURNAL OF IMMUNOLOGY
- Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus
- (2014) Christophe Guilluy et al. NATURE CELL BIOLOGY
- Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix
- (2014) R. J. Petrie et al. SCIENCE
- Nuclear Positioning
- (2013) Gregg G. Gundersen et al. CELL
- Nesprins: from the nuclear envelope and beyond
- (2013) Dipen Rajgor et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling
- (2013) Monika Zwerger et al. HUMAN MOLECULAR GENETICS
- Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
- (2013) Katarina Wolf et al. JOURNAL OF CELL BIOLOGY
- Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease
- (2013) D R Cook et al. ONCOGENE
- Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins
- (2013) J. Seong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- From Mechanical Force to RhoA Activation
- (2012) Elizabeth C. Lessey et al. BIOCHEMISTRY
- Localized Tensional Forces on PECAM-1 Elicit a Global Mechanotransduction Response via the Integrin-RhoA Pathway
- (2012) Caitlin Collins et al. CURRENT BIOLOGY
- Mechanosensitive mechanisms in transcriptional regulation
- (2012) Akiko Mammoto et al. JOURNAL OF CELL SCIENCE
- Microtubules regulate GEF-H1 in response to extracellular matrix stiffness
- (2012) Jessica N. Heck et al. MOLECULAR BIOLOGY OF THE CELL
- Nuclear Mechanics in Disease
- (2011) Monika Zwerger et al. Annual Review of Biomedical Engineering
- The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton
- (2011) Maria L. Lombardi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
- (2011) Christophe Guilluy et al. NATURE CELL BIOLOGY
- The 'invisible hand': regulation of RHO GTPases by RHOGDIs
- (2011) Rafael Garcia-Mata et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability
- (2010) Anna A. Birukova et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- p190 RhoGTPase-Activating Protein Links the β1 Integrin/Caveolin-1 Mechanosignaling Complex to RhoA and Actin Remodeling
- (2010) Baohua Yang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation
- (2010) Ana M. Pasapera et al. JOURNAL OF CELL BIOLOGY
- Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
- (2010) Carsten Grashoff et al. NATURE
- Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement
- (2010) E. S. Folker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement
- (2010) G. W. G. Luxton et al. SCIENCE
- Forcing form and function: biomechanical regulation of tumor evolution
- (2010) Hongmei Yu et al. TRENDS IN CELL BIOLOGY
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- (2009) T. A. Ulrich et al. CANCER RESEARCH
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- (2009) Fangfang Peng et al. CELLULAR SIGNALLING
- Plasticity of cell migration: a multiscale tuning model
- (2009) Peter Friedl et al. JOURNAL OF CELL BIOLOGY
- Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage
- (2009) P P Provenzano et al. ONCOGENE
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- (2009) J. C. Friedland et al. SCIENCE
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- (2008) Valerie L. R. M. Verstraeten et al. AGING CELL
- Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models
- (2008) Christopher M. Hale et al. BIOPHYSICAL JOURNAL
- Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
- (2008) P.J. Stewart-Hutchinson et al. EXPERIMENTAL CELL RESEARCH
- Mechanotransduction gone awry
- (2008) Diana E. Jaalouk et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
- (2008) Ning Wang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Rapid signal transduction in living cells is a unique feature of mechanotransduction
- (2008) S. Na et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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