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Title
Insulin and Autophagy in Neurodegeneration
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-05-22
DOI
10.3389/fnins.2019.00491
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Note: Only part of the references are listed.- Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease
- (2019) Dilan Athauda et al. JAMA Neurology
- Diabetes Mellitus in a Patient With Lafora Disease: Possible Links With Pancreatic β-Cell Dysfunction and Insulin Resistance
- (2019) Ramona C. Nicolescu et al. Frontiers in Pediatrics
- Hypermetabolism in ALS is associated with greater functional decline and shorter survival
- (2018) Frederik J Steyn et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Association between TBK1 mutations and risk of amyotrophic lateral sclerosis/frontotemporal dementia spectrum: a meta-analysis
- (2018) Rongrong Cui et al. NEUROLOGICAL SCIENCES
- Protective effects of the GLP-1 mimetic exendin-4 in Parkinson's disease
- (2018) Dilan Athauda et al. NEUROPHARMACOLOGY
- Elevated nuclear phosphatase and tensin homolog (PTEN) and altered insulin signaling in substantia nigral region of patients with Parkinson’s disease
- (2018) Sathiya Sekar et al. NEUROSCIENCE LETTERS
- Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
- (2018) Diego Grassi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity
- (2018) Soh Yamamoto et al. Cell Reports
- Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy
- (2018) Joji M. Y. Teves et al. Frontiers in Neuroscience
- The Role of Insulin/IGF-1/PI3K/Akt/GSK3β Signaling in Parkinson's Disease Dementia
- (2018) Liying Yang et al. Frontiers in Neuroscience
- Inhibition of mTORC1 Signaling Reverts Cognitive and Affective Deficits in a Mouse Model of Parkinson’s Disease
- (2018) Débora Masini et al. Frontiers in Neurology
- The Therapeutic Potential of Metformin in Neurodegenerative Diseases
- (2018) Carola Rotermund et al. Frontiers in Endocrinology
- Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
- (2018) Dagmar E. Ehrnhoefer et al. Acta Neuropathologica Communications
- 6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway
- (2018) Yasuomi Urano et al. Autophagy
- Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice
- (2018) Yoelvis García-Mesa et al. JOURNAL OF ALZHEIMERS DISEASE
- A C9orf72–CARM1 axis regulates lipid metabolism under glucose starvation-induced nutrient stress
- (2018) Yang Liu et al. GENES & DEVELOPMENT
- Insulin deficiency: A possible link between obesity and cognitive function
- (2017) Ghazaleh Nameni et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats
- (2017) Emanuel Candeias et al. MOLECULAR NEUROBIOLOGY
- Polyglutamine tracts regulate beclin 1-dependent autophagy
- (2017) Avraham Ashkenazi et al. NATURE
- Insulin expression in cultured astrocytes and the decrease by amyloid β
- (2017) Katsura Takano et al. NEUROCHEMISTRY INTERNATIONAL
- Metformin lowers α-synuclein phosphorylation and upregulates neurotrophic factor in the MPTP mouse model of Parkinson's disease
- (2017) Nikita Katila et al. NEUROPHARMACOLOGY
- Treadmill Exercise Attenuates α-Synuclein Levels by Promoting Mitochondrial Function and Autophagy Possibly via SIRT1 in the Chronic MPTP/P-Induced Mouse Model of Parkinson’s Disease
- (2017) Jung-Hoon Koo et al. NEUROTOXICITY RESEARCH
- A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease
- (2017) Altea Rocchi et al. PLoS Genetics
- Risk of Incident Alzheimer's Disease in Diabetic Patients: A Systematic Review of Prospective Trials
- (2017) Daniel Kopf et al. JOURNAL OF ALZHEIMERS DISEASE
- Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline
- (2016) David J. Koss et al. ACTA NEUROPATHOLOGICA
- Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability
- (2016) Cristina García-Cáceres et al. CELL
- Gut Permeability and Microbiota in Parkinson’s Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatonergic Pathways
- (2016) George Anderson et al. CURRENT PHARMACEUTICAL DESIGN
- Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I
- (2016) Ana M. Fernandez et al. DIABETES
- The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy
- (2016) Christopher P Webster et al. EMBO JOURNAL
- Caloric restriction and the precision-control of autophagy: A strategy for delaying neurodegenerative disease progression
- (2016) C. Ntsapi et al. EXPERIMENTAL GERONTOLOGY
- Metformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson’s Disease via Autophagy and Mitochondrial ROS Clearance
- (2016) Ming Lu et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Characterization of axonal transport defects in Drosophila Huntingtin mutants
- (2016) Kurt R. Weiss et al. JOURNAL OF NEUROGENETICS
- Insulin resistance and Parkinson’s disease: A new target for disease modification?
- (2016) D. Athauda et al. PROGRESS IN NEUROBIOLOGY
- The Parkinson’s disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway
- (2016) Carla F. Bento et al. Nature Communications
- Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling
- (2016) Janet Ugolino et al. PLoS Genetics
- Insulin-Like Growth Factor-1 but Not Insulin Predicts Cognitive Decline in Huntington’s Disease
- (2016) Linda Salem et al. PLoS One
- Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment
- (2016) Isabel Onofre et al. Scientific Reports
- Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD
- (2015) Antonella Tramutola et al. JOURNAL OF NEUROCHEMISTRY
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- Brain GLP-1 and insulin sensitivity
- (2015) Darleen Sandoval et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Huntingtin facilitates selective autophagy
- (2015) Amir Gelman et al. NATURE CELL BIOLOGY
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
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- (2015) Frank Roloff et al. PLoS One
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
- (2015) E. T. Cirulli et al. SCIENCE
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- (2015) Pui-Mun Wong et al. Nature Communications
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- (2015) Xigui Chen et al. Scientific Reports
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- (2015) Marianthi-Anna Kioumourtzoglou et al. JAMA Neurology
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- (2015) Marc Schneeberger et al. Scientific Reports
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- (2014) G Filomeni et al. CELL DEATH AND DIFFERENTIATION
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells
- (2014) Ismail Ismailoglu et al. DEVELOPMENTAL BIOLOGY
- Prior medical conditions and the risk of amyotrophic lateral sclerosis
- (2014) Meinie Seelen et al. JOURNAL OF NEUROLOGY
- The Regulation of Autophagosome Dynamics by Huntingtin and HAP1 Is Disrupted by Expression of Mutant Huntingtin, Leading to Defective Cargo Degradation
- (2014) Y. C. Wong et al. JOURNAL OF NEUROSCIENCE
- Exercise matters in patients with PD—another piece of evidence
- (2014) Georg Ebersbach Nature Reviews Neurology
- Comparison of the independent and combined effects of sub-chronic therapy with metformin and a stable GLP-1 receptor agonist on cognitive function, hippocampal synaptic plasticity and metabolic control in high-fat fed mice
- (2014) Rachael Lennox et al. NEUROPHARMACOLOGY
- Neuroprotective effect of metformin in MPTP-induced Parkinson’s disease in mice
- (2014) S.P. Patil et al. NEUROSCIENCE
- Back to the basics: Regular exercise matters in Parkinson's disease: Results from the National Parkinson Foundation QII Registry study
- (2014) O. Oguh et al. PARKINSONISM & RELATED DISORDERS
- Reducing Igf-1r Levels Leads To Paradoxical and Sexually Dimorphic Effects in HD Mice
- (2014) Silvia Corrochano et al. PLoS One
- Huntingtin Is Critical Both Pre- and Postsynaptically for Long-Term Learning-Related Synaptic Plasticity in Aplysia
- (2014) Yun-Beom Choi et al. PLoS One
- Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism
- (2013) Congcong He et al. CELL
- IGF-1 receptor antagonism inhibits autophagy
- (2013) Maurizio Renna et al. HUMAN MOLECULAR GENETICS
- Rapamycin protects the mitochondria against oxidative stress and apoptosis in a rat model of Parkinson’s disease
- (2013) JIANHUA JIANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease
- (2013) Giselle M Petzinger et al. LANCET NEUROLOGY
- IGF-1 Intranasal Administration Rescues Huntington's Disease Phenotypes in YAC128 Mice
- (2013) Carla Lopes et al. MOLECULAR NEUROBIOLOGY
- The epidemiology of ALS: a conspiracy of genes, environment and time
- (2013) Ammar Al-Chalabi et al. Nature Reviews Neurology
- Prediagnostic body fat and risk of death from amyotrophic lateral sclerosis: The EPIC cohort
- (2013) V. Gallo et al. NEUROLOGY
- Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells
- (2013) Y. Liu et al. NEUROSCIENCE
- Six Weeks of Voluntary Exercise don’t Protect C57BL/6 Mice Against Neurotoxicity of MPTP and MPP+
- (2013) Aderbal S. Aguiar et al. NEUROTOXICITY RESEARCH
- Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy
- (2013) Y. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Shared dysregulated pathways lead to Parkinson's disease and diabetes
- (2013) Jose A. Santiago et al. TRENDS IN MOLECULAR MEDICINE
- Insulin signaling regulates neurite growth during metamorphic neuronal remodeling
- (2013) T. Gu et al. Biology Open
- The molecular basis of the frontotemporal lobar degeneration–amyotrophic lateral sclerosis spectrum
- (2012) Tim van Langenhove et al. ANNALS OF MEDICINE
- Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production
- (2012) Arya E. Mehran et al. Cell Metabolism
- Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue
- (2012) X. Julia Xu et al. JOURNAL OF LIPID RESEARCH
- Dementia is associated with Insulin Resistance in patients with Parkinson's Disease
- (2012) Domenico Bosco et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
- (2012) Holly B. Kordasiewicz et al. NEURON
- Physical training exerts neuroprotective effects in the regulation of neurochemical factors in an animal model of Parkinson’s disease
- (2012) T. Tuon et al. NEUROSCIENCE
- Rapamycin treatment augments motor neuron degeneration in SOD1G93Amouse model of amyotrophic lateral sclerosis
- (2011) Xiaojie Zhang et al. Autophagy
- Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease
- (2011) Isabel Nascimento-Ferreira et al. BRAIN
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- Multimodality Imaging of -Cells in Mouse Models of Type 1 and 2 Diabetes
- (2011) J. Yong et al. DIABETES
- Diabetes and the Risk of Developing Parkinson's Disease in Denmark
- (2011) E. Schernhammer et al. DIABETES CARE
- Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb
- (2011) Tomoko Kuwabara et al. EMBO Molecular Medicine
- Insulin Receptor Substrate 2 Expression and Involvement in Neuronal Insulin Resistance in Diabetic Neuropathy
- (2011) C. W. Grote et al. Experimental Diabetes Research
- Soluble Aβ oligomer production and toxicity
- (2011) Megan E. Larson et al. JOURNAL OF NEUROCHEMISTRY
- Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
- (2011) Cristian A Lasagna-Reeves et al. Molecular Neurodegeneration
- Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis
- (2011) Sabrina Paganoni et al. MUSCLE & NERVE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- Short-term fasting induces profound neuronal autophagy
- (2010) Mehrdad Alirezaei et al. Autophagy
- Impaired autophagy in Lafora disease
- (2010) Erwin Knecht et al. Autophagy
- Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice
- (2010) A. Maida et al. DIABETOLOGIA
- Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein
- (2010) Barry Boland et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau
- (2010) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- Pathogenic Lysosomal Depletion in Parkinson's Disease
- (2010) B. Dehay et al. JOURNAL OF NEUROSCIENCE
- The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
- (2010) Maria Filimonenko et al. MOLECULAR CELL
- Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
- (2010) Marta Martinez-Vicente et al. NATURE NEUROSCIENCE
- Insulin receptor signaling in the development of neuronal structure and function
- (2010) Shu-Ling Chiu et al. Neural Development
- High insulinlike growth factor I is associated with cognitive decline in Huntington disease
- (2010) N. Saleh et al. NEUROLOGY
- Caloric Restriction Shortens Lifespan through an Increase in Lipid Peroxidation, Inflammation and Apoptosis in the G93A Mouse, an Animal Model of ALS
- (2010) Barkha P. Patel et al. PLoS One
- Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex
- (2010) Philipp A. Jaeger et al. PLoS One
- The impact of dietary energy intake on cognitive aging
- (2010) Mattson Frontiers in Aging Neuroscience
- Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
- (2009) Fiona M. Menzies et al. BRAIN
- The Protein Kinase IKKɛ Regulates Energy Balance in Obese Mice
- (2009) Shian-Huey Chiang et al. CELL
- TANK-binding kinase 1 mediates phosphorylation of insulin receptor at serine residue 994: a potential link between inflammation and insulin resistance
- (2009) Marina C Muñoz et al. JOURNAL OF ENDOCRINOLOGY
- Enhanced NMDA Receptor-Mediated Synaptic Transmission, Enhanced Long-Term Potentiation, and Impaired Learning and Memory in Mice Lacking IRSp53
- (2009) M.-H. Kim et al. JOURNAL OF NEUROSCIENCE
- Discovery of Atg5/Atg7-independent alternative macroautophagy
- (2009) Yuya Nishida et al. NATURE
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- (2008) Chie Ebato et al. Cell Metabolism
- Prospective Cohort Study of Type 2 Diabetes and the Risk of Parkinson's Disease
- (2008) J. A. Driver et al. DIABETES CARE
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- (2008) Elizabeth L. Axe et al. JOURNAL OF CELL BIOLOGY
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
- (2008) Fiona Pickford et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
- Regulation of TORC1 by Rag GTPases in nutrient response
- (2008) Eunjung Kim et al. NATURE CELL BIOLOGY
- Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
- (2008) L. Dupuis et al. NEUROLOGY
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