Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival

Compensatory activation of ERK1/2 inAtg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death

(2014) Jong-Ok Pyo et al.   Autophagy

Oxidative Stress and Autophagy in Cardiovascular Homeostasis

(2013) Cyndi R. Morales et al.   ANTIOXIDANTS & REDOX SIGNALING

Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

(2013) Debapriya Dutta et al.   Autophagy

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

(2013) Joshua K. Salabei et al.   BIOCHEMICAL JOURNAL

Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: Distinct roles of superoxide anion and superoxide dismutases

(2013) Humberto Rodriguez-Rocha et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein oxidation seems to be linked to constitutive autophagy: A sex study

(2013) Ilaria Campesi et al.   LIFE SCIENCES

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impairment of Atg5-Dependent Autophagic Flux Promotes Paraquat- and MPP+-Induced Apoptosis But Not Rotenone or 6-Hydroxydopamine Toxicity

(2013) Aracely Garcia-Garcia et al.   TOXICOLOGICAL SCIENCES

Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death

(2012) Burton J. Mader et al.   ACS Chemical Neuroscience

Protein-Thiol Oxidation and Cell Death: Regulatory Role of Glutaredoxins

(2012) Erin M.G. Allen et al.   ANTIOXIDANTS & REDOX SIGNALING

Emerging Role of Protein-Protein Transnitrosylation in Cell Signaling Pathways

(2012) Tomohiro Nakamura et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

(2012) Yuqing Wang et al.   Autophagy

Autophagy

(2012) Ricky H. Bhogal et al.   Autophagy

Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation

(2012) Vitaliy O. Kaminskyy et al.   Autophagy

The end of autophagic cell death?

(2012) Shensi Shen et al.   Autophagy

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

(2012) Magdalena Frank et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

(2012) Ilaria Dando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage

(2012) Soo Han Bae et al.   Cell Metabolism

Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation

(2012) Lin Li et al.   CELLULAR SIGNALLING

Redox Signaling in Cardiac Physiology and Pathology

(2012) Joseph R. Burgoyne et al.   CIRCULATION RESEARCH

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

Mitofusins ‘bridge’ the gap between oxidative stress and mitochondrial hyperfusion

(2012) Michael T Ryan et al.   EMBO REPORTS

The intracellular redox state is a core determinant of mitochondrial fusion

(2012) Timothy Shutt et al.   EMBO REPORTS

Assurance of mitochondrial integrity and mammalian longevity by the p62–Keap1–Nrf2–Nqo1 cascade

(2012) Jeongho Kwon et al.   EMBO REPORTS

Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

(2012) Lin Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Transitory phases of autophagic death and programmed necrosis during superoxide-induced neuronal cell death

(2012) Gavin C. Higgins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

(2012) Annika Höhn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alterations in bioenergetic function induced by Parkinson’s disease mimetic compounds: lack of correlation with superoxide generation

(2012) Brian P. Dranka et al.   JOURNAL OF NEUROCHEMISTRY

Protein damage, repair and proteolysis

(2012) Niki Chondrogianni et al.   MOLECULAR ASPECTS OF MEDICINE

Keap1 degradation by autophagy for the maintenance of redox homeostasis

(2012) K. Taguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone-mediated autophagy: a unique way to enter the lysosome world

(2012) Susmita Kaushik et al.   TRENDS IN CELL BIOLOGY

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Redox Control of the Ubiquitin-Proteasome System: From Molecular Mechanisms to Functional Significance

(2011) Franziska Kriegenburg et al.   ANTIOXIDANTS & REDOX SIGNALING

Basic Principles and Emerging Concepts in the Redox Control of Transcription Factors

(2011) Regina Brigelius-Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitophagy: A Complex Mechanism of Mitochondrial Removal

(2011) Ivana Novak   ANTIOXIDANTS & REDOX SIGNALING

Conversation between apoptosis and autophagy: “Is it your turn or mine?”

(2011) Vincenzo Giansanti et al.   APOPTOSIS

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum

(2011) Dalibor Mijaljica et al.   Autophagy

Are mitochondrial reactive oxygen species required for autophagy?

(2011) Jianfei Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Necroptosis: An emerging form of programmed cell death

(2011) Wei Wu et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress

(2011) Tilman Grune et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell sensitivity to oxidative stress is influenced by ferritin autophagy

(2011) Tino Kurz et al.   FREE RADICAL BIOLOGY AND MEDICINE

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enhanced Autophagy from Chronic Toxicity of Iron and Mutant A53T α-Synuclein

(2011) Katherine C. M. Chew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alsin and SOD1G93AProteins Regulate Endosomal Reactive Oxygen Species Production by Glial Cells and Proinflammatory Pathways Responsible for Neurotoxicity

(2011) Qiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of Hepatic Nuclear Superoxide Production by Glucose 6-Phosphate Dehydrogenase and NADPH Oxidase-4

(2011) Netanya Y. Spencer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast

(2011) Yusuke Kurihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

On the role of autophagy in human diseases: a gender perspective

(2011) Pasquale Lista et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells

(2011) T. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

Complex Inhibitory Effects of Nitric Oxide on Autophagy

(2011) Sovan Sarkar et al.   MOLECULAR CELL

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

Starvation Induced Cell Death in Autophagy-Defective Yeast Mutants Is Caused by Mitochondria Dysfunction

(2011) Sho W. Suzuki et al.   PLoS One

2-Deoxy-D-Glucose Treatment of Endothelial Cells Induces Autophagy by Reactive Oxygen Species-Mediated Activation of the AMP-Activated Protein Kinase

(2011) Qilong Wang et al.   PLoS One

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts

(2011) Hyun Tae Kang et al.   PLoS One

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

(2011) H. Cheong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chelation of Lysosomal Iron Protects Dopaminergic SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide Toxicity by Precluding Autophagy and Akt Dephosphorylation

(2011) Roberta Castino et al.   TOXICOLOGICAL SCIENCES

Autophagy and Cancer

(2011) L. Y. Mah et al.   Cold Spring Harbor Perspectives in Biology

Autophagy During Cardiac Stress: Joys and Frustrations of Autophagy

(2010) Roberta A. Gottlieb et al.   Annual Review of Physiology

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy Signaling Through Reactive Oxygen Species

(2010) Ju Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

(2010) Derek Narendra et al.   Autophagy

The emerging role of autophagy in the pathophysiology of diabetes mellitus

(2010) Claudio D. Gonzalez et al.   Autophagy

Gender-related disparities in non-small cell lung cancer

(2010) Marco G. Paggi et al.   CANCER LETTERS

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Genetic control of necrosis—another type of programmed cell death

(2010) Kimberly McCall   CURRENT OPINION IN CELL BIOLOGY

Oxidative stress, insulin signaling, and diabetes

(2010) Justin L. Rains et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy, reactive oxygen species and the fate of mammalian cells

(2010) Irena Szumiel   FREE RADICAL RESEARCH

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration

(2010) Daniele Cartelli et al.   JOURNAL OF NEUROCHEMISTRY

Pathogenic Lysosomal Depletion in Parkinson's Disease

(2010) B. Dehay et al.   JOURNAL OF NEUROSCIENCE

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes

(2010) Emeric Deruy et al.   PLoS One

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Inhibition of PI3k Class III–Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells

(2010) Roberta Castino et al.   TOXICOLOGICAL SCIENCES

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling

(2010) Dong-Min Shin et al.   PLoS Pathogens

The late stage of autophagy: cellular events and molecular regulation

(2010) Jingjing Tong et al.   Protein & Cell

Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease

(2009) Betty S. van der Veen et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Activity Within the Lysosomal Compartment: Implications for Aging and Apoptosis

(2009) Tino Kurz et al.   ANTIOXIDANTS & REDOX SIGNALING

Apoptosis and glutathione: beyond an antioxidant

(2009) R Franco et al.   CELL DEATH AND DIFFERENTIATION

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

(2009) Andrea Hall et al.   FEBS Journal

Cell sex determines anoikis resistance in vascular smooth muscle cells

(2009) Elisabetta Straface et al.   FEBS LETTERS

Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes

(2009) Peter Schönfeld et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidized proteins: Mechanisms of removal and consequences of accumulation

(2009) Rachael A. Dunlop et al.   IUBMB LIFE

Constitutive Reactive Oxygen Species Generation from Autophagosome/Lysosome in Neuronal Oxidative Toxicity

(2009) Chisato Kubota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death

(2009) Kyou-Chan Choi et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy upregulation and loss of NF-κB in oxidative stress-related immunodeficient SAMP8 mice

(2009) Beatriz Caballero et al.   MECHANISMS OF AGEING AND DEVELOPMENT

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Oxidative Stress Induces Parallel Autophagy and Mitochondria Dysfunction in Human Glioma U251 Cells

(2009) Hongyu Zhang et al.   TOXICOLOGICAL SCIENCES

Protein S-nitrosylation in health and disease: a current perspective

(2009) Matthew W. Foster et al.   TRENDS IN MOLECULAR MEDICINE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Plasma Membrane Cholesterol Content Affects Nitric Oxide Diffusion Dynamics and Signaling

(2008) Shane Miersch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY