Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline

EEG, Activity, and Sleep Architecture in a Transgenic AβPPswe/PSEN1A246E Alzheimer's Disease Mouse

(2017) Amar Jyoti et al.   JOURNAL OF ALZHEIMERS DISEASE

Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum

(2016) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment

(2016) Elliott J. Mufson et al.   NEUROBIOLOGY OF AGING

Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology

(2016) David J. Koss et al.   NEUROBIOLOGY OF DISEASE

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

(2016) M. Fá et al.   Scientific Reports

Alzheimer’s disease cerebrospinal fluid biomarker in cognitively normal subjects

(2015) Jon B. Toledo et al.   BRAIN

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits

(2015) Dave J. Koss et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kinetic regime of dithiothreitol-induced aggregation of bovine serum albumin

(2015) Vera A. Borzova et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy

(2015) Nicholas M. Kanaan et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer´s disease: appealing for ESI-IM-MS

(2015) Rosa Pujol-Pina et al.   Scientific Reports

A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis

(2014) Susana Boluda et al.   ACTA NEUROPATHOLOGICA

Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease

(2014) Markus Mandler et al.   ACTA NEUROPATHOLOGICA

Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer’s disease

(2014) Ajeet Rijal Upadhaya et al.   BRAIN

Monoclonal Antibodies against Aβ42 Fibrils Distinguish Multiple Aggregation State Polymorphismsin Vitroand in Alzheimer Disease Brain

(2014) Asa Hatami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knock-In of Human BACE1 Cleaves Murine APP and Reiterates Alzheimer-like Phenotypes

(2014) K. Pluci ska et al.   JOURNAL OF NEUROSCIENCE

Memory deficits correlate with tau and spine pathology in P301SMAPTtransgenic mice

(2014) Hong Xu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Disruption of Amyloid Plaques Integrity Affects the Soluble Oligomers Content from Alzheimer Disease Brains

(2014) Sebastian Jimenez et al.   PLoS One

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Soluble amyloid beta levels are elevated in the white matter of Alzheimer’s patients, independent of cortical plaque severity

(2014) Lyndsey E Collins-Praino et al.   Acta Neuropathologica Communications

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples

(2013) Andrew D. Watt et al.   ACTA NEUROPATHOLOGICA

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

Hyperphosphorylation-Induced Tau Oligomers

(2013) Khalid Iqbal et al.   Frontiers in Neurology

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

(2012) Katherine L Youmans et al.   Molecular Neurodegeneration

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice

(2011) Paul J. Meakin et al.   BIOCHEMICAL JOURNAL

Heat Shock Protein 70 Prevents both Tau Aggregation and the Inhibitory Effects of Preexisting Tau Aggregates on Fast Axonal Transport

(2011) Kristina R. Patterson et al.   BIOCHEMISTRY

Characterization of Prefibrillar Tau Oligomersin Vitroand in Alzheimer Disease

(2011) Kristina R. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases

(2011) N. M. Kanaan et al.   JOURNAL OF NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Preparation and Characterization of Neurotoxic Tau Oligomers

(2010) Cristian A. Lasagna-Reeves et al.   BIOCHEMISTRY

BACE1 and BACE2 enzymatic activities in Alzheimer’s disease

(2009) Rachel R. Ahmed et al.   JOURNAL OF NEUROCHEMISTRY

How do surfactants and DTT affect the size, dynamics, activity and growth of soluble lysozyme aggregates?

(2008) Satish Kumar et al.   BIOCHEMICAL JOURNAL

Amyloidogenic Processing of Amyloid Precursor Protein: Evidence of a Pivotal Role of Glutaminyl Cyclase in Generation of Pyroglutamate-Modified Amyloid-β†

(2008) Holger Cynis et al.   BIOCHEMISTRY