Translating the Hypoxic Response—the Role of HIF Protein Translation in the Cellular Response to Low Oxygen
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Title
Translating the Hypoxic Response—the Role of HIF Protein Translation in the Cellular Response to Low Oxygen
Authors
Keywords
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Journal
Cells
Volume 8, Issue 2, Pages 114
Publisher
MDPI AG
Online
2019-02-02
DOI
10.3390/cells8020114
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Note: Only part of the references are listed.- miRNAs regulate the HIF switch during hypoxia: a novel therapeutic target
- (2018) Marcin Serocki et al. ANGIOGENESIS
- Prolyl Hydroxylase Inhibitors: A Breakthrough in the Therapy of Anemia Associated with Chronic Diseases
- (2018) Amit A. Joharapurkar et al. JOURNAL OF MEDICINAL CHEMISTRY
- PERK/eIF2α signaling inhibits HIF-induced gene expression during the unfolded protein response via YB1-dependent regulation of HIF1α translation
- (2018) Iglika G Ivanova et al. NUCLEIC ACIDS RESEARCH
- Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis
- (2018) Huichun Liang et al. ONCOGENE
- Cold-inducible RNA binding protein in cancer and inflammation
- (2018) Daniel A. Lujan et al. Wiley Interdisciplinary Reviews-RNA
- Regulation of microRNA function in animals
- (2018) Luca F. R. Gebert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin
- (2018) James A Smythies et al. EMBO REPORTS
- miRNA networks modulate human endothelial cell adaptation to cyclic hypoxia
- (2018) Kinga Kochan-Jamrozy et al. CELLULAR SIGNALLING
- Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia
- (2017) Guillaume Gauchotte et al. JOURNAL OF PATHOLOGY
- An emergency brake for protein synthesis
- (2017) Vladislava Hronová et al. eLife
- Role of Y Box Protein-1 in cancer: As potential biomarker and novel therapeutic target
- (2017) Pramod Kumar Maurya et al. Journal of Cancer
- MiR-150 regulates human keratinocyte proliferation in hypoxic conditions through targeting HIF-1α and VEGFA: Implications for psoriasis treatment
- (2017) Yongjian Li et al. PLoS One
- Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
- (2016) Caroline Wigerup et al. PHARMACOLOGY & THERAPEUTICS
- Translational control by 5'-untranslated regions of eukaryotic mRNAs
- (2016) A. G. Hinnebusch et al. SCIENCE
- Dysregulation of TTP and HuR plays an important role in cancers
- (2016) Hao Wang et al. TUMOR BIOLOGY
- Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
- (2016) Julianty Frost et al. Nature Communications
- Role of Mir-155 in Controlling HIF-1α Level and Promoting Endothelial Cell Maturation
- (2016) Deguang Yang et al. Scientific Reports
- miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells
- (2016) Anna Janaszak-Jasiecka et al. Scientific Reports
- Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis
- (2015) Amal M. El-Naggar et al. CANCER CELL
- HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
- (2015) T. Bishop et al. CIRCULATION RESEARCH
- The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop
- (2015) Sylwia Bartoszewska et al. FASEB JOURNAL
- YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1
- (2015) Syam Prakash Somasekharan et al. JOURNAL OF CELL BIOLOGY
- Translating the Untranslated Region
- (2015) Johannes Schwerk et al. JOURNAL OF IMMUNOLOGY
- Structural integration in hypoxia-inducible factors
- (2015) Dalei Wu et al. NATURE
- Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
- (2015) Jonas J. Staudacher et al. NUCLEIC ACIDS RESEARCH
- Genome-wide analysis of YB-1-RNA interactions reveals a novel role of YB-1 in miRNA processing in glioblastoma multiforme
- (2015) Shuai-Lai Wu et al. NUCLEIC ACIDS RESEARCH
- CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis
- (2015) K Nagaoka et al. ONCOGENE
- miR-497 suppresses angiogenesis in breast carcinoma by targeting HIF-1α
- (2015) ZHIHAO WU et al. ONCOLOGY REPORTS
- microRNA-18a regulates gastric carcinoma cell apoptosis and invasion by suppressing hypoxia-inducible factor-1α expression
- (2015) FUBING WU et al. Experimental and Therapeutic Medicine
- Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation
- (2015) Seong-Jun Cho et al. Oncotarget
- HIF Transcription Factors, Inflammation, and Immunity
- (2014) Asis Palazon et al. IMMUNITY
- Regulation of microRNA biogenesis
- (2014) Minju Ha et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axis
- (2014) D Zhang et al. Cell Death & Disease
- Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action
- (2013) Seth A. Brooks et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2 mRNA translation
- (2013) N. Wilkinson et al. BLOOD
- The eIF2α kinases: their structures and functions
- (2013) Neysan Donnelly et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- New Insights into Functional Roles of the Polypyrimidine Tract-Binding Protein
- (2013) Maria Romanelli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- RNPC1, an RNA-binding Protein and a p53 Target, Regulates Macrophage Inhibitory Cytokine-1 (MIC-1) Expression through mRNA Stability
- (2013) Tiffany Yin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Restricted Expression of miR-30c-2-3p and miR-30a-3p in Clear Cell Renal Cell Carcinomas Enhances HIF2 Activity
- (2013) L. K. Mathew et al. Cancer Discovery
- YB-1 protein: functions and regulation
- (2013) Dmitry N. Lyabin et al. Wiley Interdisciplinary Reviews-RNA
- Tristetraprolin: Roles in cancer and senescence
- (2012) Christina R. Ross et al. AGEING RESEARCH REVIEWS
- Y-box-binding protein 1 (YB-1) and its functions
- (2012) I. A. Eliseeva et al. BIOCHEMISTRY-MOSCOW
- Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction
- (2012) Seul Gi Kang et al. CARCINOGENESIS
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- An oxygen-regulated switch in the protein synthesis machinery
- (2012) James Uniacke et al. NATURE
- MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha
- (2012) H Zhang et al. ONCOGENE
- Passing the baton: the HIF switch
- (2012) Mei Yee Koh et al. TRENDS IN BIOCHEMICAL SCIENCES
- HIF-1 versus HIF-2 — Is one more important than the other?
- (2012) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- Principles of Translational Control: An Overview
- (2012) J. W. B. Hershey et al. Cold Spring Harbor Perspectives in Biology
- Hypoxia elicits broad and systematic changes in protein subcellular localization
- (2011) Robert Michael Henke et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The role of tristetraprolin in cancer and inflammation
- (2011) Sandhya Sanduja Frontiers in Bioscience-Landmark
- Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells
- (2011) Sandrine Chamboredon et al. MOLECULAR BIOLOGY OF THE CELL
- Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR
- (2011) Svetlana Lebedeva et al. MOLECULAR CELL
- Translational control is a major contributor to hypoxia induced gene expression
- (2011) Twan van den Beucken et al. RADIOTHERAPY AND ONCOLOGY
- The role of IREStrans-acting factors in regulating translation initiation
- (2010) Helen A. King et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The Connectivity Map Links Iron Regulatory Protein-1-Mediated Inhibition of Hypoxia-Inducible Factor-2a Translation to the Anti-inflammatory 15-deoxy- 12,14-Prostaglandin J2
- (2010) M. Zimmer et al. CANCER RESEARCH
- MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis
- (2010) Shih-Ting Cha et al. CANCER RESEARCH
- Role of the hypoxia inducible factors HIF in iron metabolism
- (2010) Carole Peyssonnaux et al. CELL CYCLE
- Biological functions of microRNAs: a review
- (2010) Yong Huang et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Inhibition of Hypoxia-Inducible Factor-1α (HIF-1α) Protein Synthesis by DNA Damage Inducing Agents
- (2010) Jessica Jie Wei Lou et al. PLoS One
- P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
- (2010) M. Yamakuchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development
- (2009) CHRISTINA NEIGAARD HANSEN et al. APMIS
- Tristetraprolin regulates the stability of HIF-1α mRNA during prolonged hypoxia
- (2009) Tae Woo Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition
- (2009) Valentina Evdokimova et al. CANCER CELL
- The mRNA-Destabilizing Protein Tristetraprolin Is Suppressed in Many Cancers, Altering Tumorigenic Phenotypes and Patient Prognosis
- (2009) S. E. Brennan et al. CANCER RESEARCH
- mRNA Localization: Gene Expression in the Spatial Dimension
- (2009) Kelsey C. Martin et al. CELL
- Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
- (2009) Nahum Sonenberg et al. CELL
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Factors Interacting with HIF-1α mRNA: Novel Therapeutic Targets
- (2009) Stefanie Galban et al. CURRENT PHARMACEUTICAL DESIGN
- Surviving hypoxia by modulation of mRNA translation rate
- (2009) Michael Fähling JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Regulation of HIF-1α and VEGF by miR-20b Tunes Tumor Cells to Adapt to the Alteration of Oxygen Concentration
- (2009) Zhang Lei et al. PLoS One
- Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells
- (2009) Shi-Hua Liao et al. PROTEOMICS
- Subcellular mRNA Localization in Animal Cells and Why It Matters
- (2009) C. E. Holt et al. SCIENCE
- Regulation of gene expression by hypoxia
- (2008) Niall Steven Kenneth et al. BIOCHEMICAL JOURNAL
- Cytoplasmic polyadenylation-element-binding protein (CPEB)1 and 2 bind to theHIF-1α mRNA 3′-UTR and modulate HIF-1α protein expression
- (2008) Sonja Hägele et al. BIOCHEMICAL JOURNAL
- Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein
- (2008) Kirsty Sawicka et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Identification of Hypoxia-Inducible Factor-1 as a Novel Target for miR-17-92 MicroRNA Cluster
- (2008) A. Taguchi et al. CANCER RESEARCH
- Hypoxia regulates TSC1/2 mTOR signaling and tumor suppression through REDD1-mediated 14 3 3 shuttling
- (2008) M. P. DeYoung et al. GENES & DEVELOPMENT
- Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism
- (2008) Regina M. Young et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small-Molecule Inhibitors of HIF-2a Translation Link Its 5′UTR Iron-Responsive Element to Oxygen Sensing
- (2008) Michael Zimmer et al. MOLECULAR CELL
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- Digoxin and other cardiac glycosides inhibit HIF-1 synthesis and block tumor growth
- (2008) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional responses to intermittent hypoxia
- (2008) Jayasri Nanduri et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
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