Y-box-binding protein 1 (YB-1) and its functions

A Multiprotein Binding Interface in an Intrinsically Disordered Region of the Tumor Suppressor Protein Interferon Regulatory Factor-1

(2011) Vikram Narayan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular YB-1 Blockade in Experimental Nephritis Upregulates Notch-3 Receptor Expression and Signaling

(2011) Ute Raffetseder et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification

(2011) A H Davies et al.   ONCOGENE

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis

(2010) David H. Lovett et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

YB-1 is capable of forming extended nanofibrils

(2010) O. M. Selivanova et al.   BIOCHEMISTRY-MOSCOW

Twist1 and Y-box-binding protein-1 promote malignant potential in bladder cancer cells

(2010) Masaki Shiota et al.   BJU INTERNATIONAL

Y-Box Binding Protein-1 Induces the Expression ofCD44andCD49fLeading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance

(2010) Karen To et al.   CANCER RESEARCH

P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistance

(2010) Masaki Shiota et al.   CANCER SCIENCE

Foxo3a Suppression of Urothelial Cancer Invasiveness through Twist1, Y-Box-Binding Protein 1, and E-Cadherin Regulation

(2010) M. Shiota et al.   CLINICAL CANCER RESEARCH

Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells

(2010) Yuji Basaki et al.   EUROPEAN JOURNAL OF CANCER

YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma

(2010) Regina Holzmüller et al.   INTERNATIONAL JOURNAL OF CANCER

A Novel Small Compound That Promotes Nuclear Translocation of YB-1 Ameliorates Experimental Hepatic Fibrosis in Mice

(2010) Kiyoshi Higashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Y-Box Binding Protein-1, a Predictive Marker of Prognosis, Is Correlated with Expression of HER2/ErbB2 and HER3/ErbB3 in Non-small Cell Lung Cancer

(2010) Masaki Kashihara et al.   Journal of Thoracic Oncology

Cotranscriptional exon skipping in the genotoxic stress response

(2010) Martin Dutertre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1

(2010) J Kalra et al.   ONCOGENE

Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

(2010) S Sengupta et al.   ONCOGENE

Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1

(2010) L C Cobbold et al.   ONCOGENE

A Conserved Stem Loop Motif in the 5′Untranslated Region Regulates Transforming Growth Factor-β1 Translation

(2010) Robert H. Jenkins et al.   PLoS One

Molecular Decoy to the Y-Box Binding Protein-1 Suppresses the Growth of Breast and Prostate Cancer Cells whilst Sparing Normal Cell Viability

(2010) Jennifer H. Law et al.   PLoS One

Contribution of proton linkage to the thermodynamic stability of the major cold-shock protein of Escherichia coli CspA

(2010) Susan A. Petrosian et al.   PROTEIN SCIENCE

RNA-binding specificity of Y-box protein 1

(2010) Jinjiang Dong et al.   RNA Biology

A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis

(2009) Minoru Hasegawa et al.   ARTHRITIS AND RHEUMATISM

HSP60 interacts with YB-1 and affects its polysome association and subcellular localization

(2009) Sachiyo Ohashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition

(2009) Valentina Evdokimova et al.   CANCER CELL

Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo

(2009) E Rognoni et al.   CANCER GENE THERAPY

Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth

(2009) M. Shiota et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen

(2009) Björn C Frye et al.   EMBO REPORTS

Nuclear expression of YB-1 in diffuse large B-cell lymphoma: correlation with disease activity and patient outcome

(2009) WenLing Xu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Y-Box Binding Protein-1 Down-Regulates Expression of Carbamoyl Phosphate Synthetase-I by Suppressing CCAAT Enhancer-Binding Protein-Alpha Function in Mice

(2009) Yen–Rong Chen et al.   GASTROENTEROLOGY

Role of Microtubules in Stress Granule Assembly

(2009) Konstantin G. Chernov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YB-1 Acts as a Ligand for Notch-3 Receptors and Modulates Receptor Activation

(2009) Thomas Rauen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YB-1 transcription in the postnatal brain is regulated by a bHLH transcription factor Math2 through an E-box sequence in the 5′-UTR of the gene

(2009) Sachiyo Ohashi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Transforming Growth Factor β1-mediated Activation of the Smooth Muscle α-Actin Gene in Human Pulmonary Myofibroblasts Is Inhibited by Tumor Necrosis Factor-α via Mitogen-activated Protein Kinase Kinase 1-dependent Induction of the Egr-1 Transcriptional Repressor

(2009) Xiaoying Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase

(2009) Y. Gao et al.   MOLECULAR CANCER THERAPEUTICS

The transcriptional induction of PIK3CA in tumor cells is dependent on the oncoprotein Y-box binding protein-1

(2009) A Astanehe et al.   ONCOGENE

Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells

(2009) M R Finkbeiner et al.   ONCOGENE

YB-1 promotes microtubule assembly in vitro through interaction with tubulin and microtubules

(2008) Konstantin G Chernov et al.   BMC BIOCHEMISTRY

Expression of HER2 and Estrogen Receptor   Depends upon Nuclear Localization of Y-Box Binding Protein-1 in Human Breast Cancers

(2008) T. Fujii et al.   CANCER RESEARCH

Targeting YB-1 in HER-2 Overexpressing Breast Cancer Cells Induces Apoptosis via the mTOR/STAT3 Pathway and Suppresses Tumor Growth in Mice

(2008) Cathy Lee et al.   CANCER RESEARCH

Twist Promotes Tumor Cell Growth through YB-1 Expression

(2008) M. Shiota et al.   CANCER RESEARCH

The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y-box-binding protein-1 overexpressing tumor cells

(2008) David Guay et al.   CANCER SCIENCE

Different expression profiles of Y-box-binding protein-1 and multidrug resistance-associated proteins between alveolar and embryonal rhabdomyosarcoma

(2008) Yoshinao Oda et al.   CANCER SCIENCE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation

(2008) Yuri V Svitkin et al.   EMBO JOURNAL

The pathological splicing mutation c.6792C > G inNF1exon 37 causes a change of tenancy between antagonistic splicing factors

(2008) Natasa Skoko et al.   FEBS LETTERS

The strand separation and nuclease activities associated with YB-1 are dispensable for cisplatin resistance but overexpression of YB-1 in MCF7 and MDA-MB-231 breast tumor cells generates several chemoresistance signatures

(2008) David Guay et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

RBBP6 Interacts with Multifunctional Protein YB-1 through Its RING Finger Domain, Leading to Ubiquitination and Proteosomal Degradation of YB-1

(2008) Moredreck Chibi et al.   JOURNAL OF MOLECULAR BIOLOGY

MBNL1 associates with YB-1 in cytoplasmic stress granules

(2008) Hayato Onishi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1

(2008) U.t.e. Raffetseder et al.   KIDNEY INTERNATIONAL

Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1

(2008) R. Chattopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma

(2007) M. Chatterjee et al.   BLOOD